• Title/Summary/Keyword: Exact test

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Accuracy and Precision of Three-dimensional Imaging System of Children's Facial Soft Tissue (소아 얼굴 연조직의 3차원 입체영상의 정확성 및 재현성 평가)

  • Choi, Kyunghwa;Kim, Misun;Lee, Koeun;Nam, Okhyung;Lee, Hyo-seol;Choi, Sungchul;Kim, Kwangchul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.47 no.1
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    • pp.17-24
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    • 2020
  • The purpose of this study was to evaluate the accuracy and precision of the three-dimensional (3D) imaging system of children's facial soft tissue by comparing linear measurements. The subjects of the study were 15 children between the ages of 7 and 12. Twenty-three landmarks were pointed on the face of each subject and 16 linear measurements were directly obtained 2 times using an electronic caliper. Two sets of 3D facial images were made by the 3D scanner. The same 16 measurements were obtained on each 3D image. In the accuracy test, the total average difference was 0.9 mm. The precision of 3D photogrammetry was almost equivalent to that of direct measurement. Thus, 3D photogrammetry by the 3D scanner in children had sufficient accuracy and precision to be used in clinical setting. However, the 3D imaging system requires the subject's compliance for exact images. If the clinicians provide specific instructions to children while obtaining 3D images, the 3D device is useful for investigating children's facial growth and development. Also the device can be a valuable tool for evaluating the results of orthodontic and orthopedic treatments.

Analyzing the Cognition of CPR by College Students Who Major in Public Health or Not (보건계열과 비보건계열 대학생의 심폐소생술에 대한 인지도)

  • Kwon, Hayrran
    • The Korean Journal of Emergency Medical Services
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    • v.4 no.1
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    • pp.35-46
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    • 2000
  • The results of analyzing the cognition of CPR by college students who major in public health or not order to enhance the educational efficiency of first aid ability and its expansion are as follows. 1. In case of students majoring in public health, the students who have the knowledge of term 'CPR' are 95.3% of total 300 students and 62.6% of the students who don't major in public health know it. In the item test of examining the degree of theoretical knowledge of CPR, the cases who know all 12 items are 5.2% and 1.6% respectively in cases who major in public health and don't major in it and it is judged that the extension of educational opportunity for them should be urgent. 2. The students who have experienced the practice of CPR are 20.6% in case who major in public health and 7.4% in other case. Therefore it seems to desirable that indirect field experience should be obtained by strengthening practice centered education. 3. The order of practice to examine the CPR ability is asked and the students who show very good remark are just 21~22% in both cases and they conducted very ineffective CPR and it is examined that they did first aid which may a serious damage to patients. Then the cases who recovered pulse and respiration after CPR were very low as 28.8% in the students who major in public health and 35.7% in others. It is therefore considered that the exact education of conducting the maintenance of respiratory trace, artificial respiration and CPR is necessary. 4. The cases who had the education of CPR were 51% in the students who major in public health and 39.4% in others, who had little opportunities to have CPR and 92.5~93.2% in both groups fee the necessity of continuous education and it is very encouraging to extend the education of CPR. 5. The education of CPR is mainly done at school (70.3~79.4%) and from teachers (52.7~55.4%) and 71.2% of the students majoring in public health responded that it is good for them to have education of CPR at school and lecture by first-aider and 58.9% of others did it. The cases who ask for lecture by the Professors of Dept. of First-Aid are 11.8 in students majoring in public health and 13.1% in others and it is judged that lecture by them having the theoretical foundation and first-aider with practical ability will be desirable. 6. On teaching methods, 57.5% of the cases majoring in public health and 63.3% of others ask for practice and 20% of both groups need theory centered teaching. 7. On lecture fee, 83% of the cases majoring in public health and 83.3% of others consider it should be free and 8~11.8% who are to pay for 10,000 won and it is judged that it should be opened and operated as liberal arts by college in the dimension of lifelong education. 8. On the objects of education, 83% of cases majoring in public health and 66.6% of others consider it should be conducted in people of all ages and both sexes and it is known that everyone recognizes the necessity of popularizing the education of first-aid.

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Surgical Results for Perforated Gastric Cancer (천공성 위암의 수술 방법과 치료 결과)

  • Lee, Moon-Soo;Chae, Man-Kyu;Kim, Tae-Yun;Cho, Gyu-Seok;Kim, Sung-Yong;Baek-Moo-Jun;Chung-Il-Kwon;Park, Kyung-Kyu;Kim, Chang-Ho;Song-Ok-Pyung;Cho, Moo-Sik
    • Journal of Gastric Cancer
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    • v.2 no.2
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    • pp.85-90
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    • 2002
  • Purpose: Perforated gastric cancer (PGC) is rare and occurs in $1\∼4\%$ of all gastric cancers. Possible dissemination of tumor cells at the time of perforation of the gastric carcinoma has been a matter of concern. The intraoperative determination of what kind of operation should be done and how extensive the lymphnode dissection should be still remains controversial. The purpose of this study is to evaluate the factors influencing the survival and to determine the optimal treatment for PGC. Materials and Methods: A total of 42 patients were operated on for a perforated gastric carcinoma at Soonchunhyang University Chunan Hospital from 1983 to 2000. the age and the sexes of the patients, the location of perforation, the diameter of perforation, the histologic type of the tumor, the depth of wall invasion, the absence or presence of lymph node metastasis / distant metastasis, the stage of disease, the type of operation, and the outcomes were examined. Statistically significant differences were analyzed by using Fisher's exact test. Results: The stage distributions according to the UICC classification were 1 case of stage I, 6 cases of stage II, 17 cases of stage III, and 11 cases of stage IV. An emergency gastrectomy was done in 26 patients ($61.9\%$), with a 5-yr survival rate of $44\%$. The survival of patients was significantly influenced by the depth of wall invasion, the lymphnode metastasis, distant metastasis, the stage of disease, and the type of operation. Conclusions: an emergency gastrectomy is the treatment of choice for most patients with resectable PGC. Choosing more a optimistic surgical approach for potentially curative cases of PGC should be one way to increase the patient's survival rate.

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Census Population vs. Registration Population: Which Population Denominator Should be used to Calculate Geographical Mortality (센서스인구 대 주민등록인구: 지역별 사망률 연구에서 어느 인구를 분모로 사용하여야 하나?)

  • Hwang, In-A;Yun, Sung-Cheol;Lee, Moo-Song;Lee, Sang-Il;Jo, Min-Woo;Lee, Min-Jung;Khang, Young-Ho
    • Journal of Preventive Medicine and Public Health
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    • v.38 no.2
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    • pp.147-153
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    • 2005
  • Objectives: Studies on the geographical differences in mortality tend to use a census population, rather than a registration population, as the denominator of mortality rates in South Korea. However, an administratively determined registration population would be the logical denominator, as the geographical areas for death certificates (numerator) have been determined by the administratively registered residence of the deceased, rather than the actual residence at the time of death. The purpose of this study was to examine the differences in the total number of a district population, and the associated district-specific mortality indicators, when two different measures as a population denominator (census and registration) were used. Methods: Population denominators were obtained from census and registration population data, and the numbers of deaths (numerators) were calculated from raw death certificate data. Sex- and 5-year age-specific numbers for the populations and deaths were used to compute sex- and age-standardized mortality rates (by direct standardization methods) and standardized mortality ratios (by indirect standardization methods). Bland-Altman tests were used to compare district populations and district-specific mortality indicators according to the two different population denominators. Results : In 1995, 9 of 232 (3.9%) districts were not included in the 95% confidence interval (CI) of the population differences. A total of 8 (3.4%) among 234 districts had large differences between their census and registration populations in 2000, which exceeded the 95% CI of the population differences. Most districts (13 of 17) exceeding the 95% CI were rural. The results of the sex- and age-standardized mortality rates showed 15 (6.5%) and 16 (6.8%) districts in 1995 and 2000, respectively, were not included in the 95% CI of the differences in their rates. In addition, the differences in the standardized mortality ratios using the two different population denominators were significantly greater among 14 districts in 1995 and 11 districts in 2002 than the 95% CI. Geographical variations in the mortality indicators, using a registration population, were greater than when using a census population. Conclusion: The use of census population denominators may provide biased geographical mortality indicators. The geographical mortality rates when using registration population denominators are logical, but do not necessarily represent the exact mortality rate of a certain district. The removal of districts with large differences between their census and registration populations or associated mortality indicators should be considered to monitor geographical mortality rates in South Korea.

Camera Motion Estimation using Geometrically Symmetric Points in Subsequent Video Frames (인접 영상 프레임에서 기하학적 대칭점을 이용한 카메라 움직임 추정)

  • Jeon, Dae-Seong;Mun, Seong-Heon;Park, Jun-Ho;Yun, Yeong-U
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.39 no.2
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    • pp.35-44
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    • 2002
  • The translation and the rotation of camera occur global motion which affects all over the frame in video sequence. With the video sequences containing global motion, it is practically impossible to extract exact video objects and to calculate genuine object motions. Therefore, high compression ratio cannot be achieved due to the large motion vectors. This problem can be solved when the global motion compensated frames are used. The existing camera motion estimation methods for global motion compensation have a large amount of computations in common. In this paper, we propose a simple global motion estimation algorithm that consists of linear equations without any repetition. The algorithm uses information .of symmetric points in the frame of the video sequence. The discriminant conditions to distinguish regions belonging to distant view from foreground in the frame are presented. Only for the distant view satisfying the discriminant conditions, the linear equations for the panning, tilting, and zooming parameters are applied. From the experimental results using the MPEG test sequences, we can confirm that the proposed algorithm estimates correct global motion parameters. Moreover the real-time capability of the proposed technique can be applicable to many MPEG-4 and MPEG-7 related areas.

Analysis of dental hygiene records applied by dental hygiene process (치위생과정을 적용한 치위생관리 기록부 분석)

  • Lee, Joon-Mee;Chung, Won-Gyun;Yoo, Jae-Ha;Kim, Nam-Hee
    • Journal of Korean society of Dental Hygiene
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    • v.9 no.4
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    • pp.768-783
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    • 2009
  • Objectives : The purpose of this study was to analyze dental records performed through a dental hygiene process and provide basic data on clinical training education for dental hygienists. Methods : The dental hygiene records of 440 senior dental hygiene students in Y University from March 2005 to September 2008, were examined. The needs of the clients confirmed by the dental hygiene diagnosis was based on Human Need Theory. The client's needs and the number of visits were analyzed according to the general characteristics(gender, age). The contents of the dental hygiene implementation performed according to the needs were divided into dental hygiene care and oral health education. The dental hygiene evaluation was classified into 'Met of Goal', 'Partially Met of Goal', and 'Unmet of Goal' according to the dental hygiene diagnosis. Data analysis was performed for the Frequency statistics and a Fisher's exact test using SPSS 12.0K for Windows. Results : 1. The clients were mostly aged in their 20's(307 clients). 2. The dental hygiene care usually performed was 'Scaling' and 'Recommendation to visit a dental clinic', and the education performed was 'How to brush teeth'. The implementation result from the need to Freedom of Stress was as simple as 'Be careful when treating' and 'Explanation of medical treatment and tools'. 3. The dental hygiene evaluation showed a higher met rate in the field of education than in that of the dental hygiene care. The reason for unmet the goal was 'Lack of the client's efforts and they didn't visit dental clinic'. Conclusions : The search for a range of clients for dental hygiene process should be made through effective connections between the local community institutions and schools. It was suggested that they should be strength the practical exercises for clients suffering dental anxiety and stress in dental treatments. In addition, education and attempts to motivate the clients should be performed according to their characteristics.

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Characteristic Evaluation of Bending Strength Distributions on Revised Korean Visual Grading Rule (개정된 육안등급 구분에 따른 휨강도 특성 평가)

  • Pang, Sung-Jun;Oh, Jung-Kwon;Park, Chun-Young;Park, Joo-Saeng;Park, Mun-Jae;Lee, Jun-Jae
    • Journal of the Korean Wood Science and Technology
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    • v.39 no.1
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    • pp.1-7
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    • 2011
  • Recently, the visual grading rule of Korea Forest Research Institute (KFRI) was revised and it is necessary to investigate the distribution characteristics of visual graded lumber in accordance with the revised rule. Therefore, in this study, the distribution characteristics of bending strength was investigated with revised visual grading rule and changed prior rule, respectively. The size of specimens was $38{\times}140{\times}3,000$ (mm) and the species were $Larix$ $kaempferi$ and $Pinus$ $koraiensis$. The moisture content was under 18% and the specimens were tested in accordance with ASTM D-198. The number of No. 1 and 2 grades, suitable for structural lumber, was increased when the revised visual grading rule was applied. Moreover, the revised rule was more effective to distinguish sharply between No. 1 and 2 grades and below No. 3 grade. Meanwhile, the lower 5% exclusion limit and allowable stresses were generally decreased when revised visual grading rule had been applied. However, the announcement of Korea Forest Service, tested with small clear specimen, was much lower than the allowable stresses of this test, tested with structural lumber. Therefore, the revision of allowable design values should be considered for more exact use and effective structural design.

Clinical Evaluation of Risk Factors Affection Postoperative Morbidity and Mortality in the Surgical Treatment of Tuberculous Destroyed Lung (결핵성 파괴폐의 수술적 치료에 대한 술후 이환율과 사망률에 영향을 미치는 위험 인자에 대한 임상고찰)

  • Shin, Sung-Ho;Chung, Won-Sang;Jee, Heng-Ok;Kang, Jung-Ho;Kim, Young-Hak;Kim, Hyuck
    • Journal of Chest Surgery
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    • v.33 no.3
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    • pp.231-239
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    • 2000
  • Background: This retrospective study tries to identify specific risk factors that may increase complication rates after the surgical treatment of tuberculous destroyed lung. Material and method: A retrospective study was performed on forty-seven patients, who received surgical treatment for tuberculous destroyed lung in the Department of Thoracic and Cardiovascular Surgery at Hanyang University Hospital from 1988 to 1998, to identify specific preoperative risk factors related to postoperative complications. Fisher's exact test was used to identify the correlations between the complications and right pneumonectomy, preoperative FEV1, predicted postoperative FEV1, massive hemoptysis, postoperative persistent empyema. Result: Hospital mortality and morbidity rates of the patients who received surgical treatment for tuberculous destroyed lung were 6.4% and 29.7%, respectively. In view of the hospital mortality and morbidity rates as a whole, predicted postoperative FEV1 less than 0.8L(p<0.005), preoperative FEV1 less than 1.8L(p=0.01), massive hemoptysis(p<0.005), postoperative persistent positive sputum cultures(p<0.0005), and the presence of multi drug resistant tuberculosis(p<0.05) presented statistically significant correlations. Among the postoperative complications, bronchopleural fistula, the most common complication, was found to have statistically significant corrleations with the preoperative empyema(p<0.05) and postoperative persistent positive sputum cultures(p<0.05). Conclusion: Although mortality and morbidity rates after surgical treatment of tuberculous destroyed lung were relatively low, when predicted postoperative FEV1 was less than 0.8L, when preoperative FEV1 was less than 1.8L, when massive hemoptysis was present, when postoperative sputum cultures were persistently positive, and when multi drug resistant tuberculosis was present, the rates were significantly higher.

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FCAnalyzer: A Functional Clustering Analysis Tool for Predicted Transcription Regulatory Elements and Gene Ontology Terms

  • Kim, Sang-Bae;Ryu, Gil-Mi;Kim, Young-Jin;Heo, Jee-Yeon;Park, Chan;Oh, Berm-Seok;Kim, Hyung-Lae;Kimm, Ku-Chan;Kim, Kyu-Won;Kim, Young-Youl
    • Genomics & Informatics
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    • v.5 no.1
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    • pp.10-18
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    • 2007
  • Numerous studies have reported that genes with similar expression patterns are co-regulated. From gene expression data, we have assumed that genes having similar expression pattern would share similar transcription factor binding sites (TFBSs). These function as the binding regions for transcription factors (TFs) and thereby regulate gene expression. In this context, various analysis tools have been developed. However, they have shortcomings in the combined analysis of expression patterns and significant TFBSs and in the functional analysis of target genes of significantly overrepresented putative regulators. In this study, we present a web-based A Functional Clustering Analysis Tool for Predicted Transcription Regulatory Elements and Gene Ontology Terms (FCAnalyzer). This system integrates microarray clustering data with similar expression patterns, and TFBS data in each cluster. FCAnalyzer is designed to perform two independent clustering procedures. The first process clusters gene expression profiles using the K-means clustering method, and the second process clusters predicted TFBSs in the upstream region of previously clustered genes using the hierarchical biclustering method for simultaneous grouping of genes and samples. This system offers retrieved information for predicted TFBSs in each cluster using $Match^{TM}$ in the TRANSFAC database. We used gene ontology term analysis for functional annotation of genes in the same cluster. We also provide the user with a combinatorial TFBS analysis of TFBS pairs. The enrichment of TFBS analysis and GO term analysis is statistically by the calculation of P values based on Fisher’s exact test, hypergeometric distribution and Bonferroni correction. FCAnalyzer is a web-based, user-friendly functional clustering analysis system that facilitates the transcriptional regulatory analysis of co-expressed genes. This system presents the analyses of clustered genes, significant TFBSs, significantly enriched TFBS combinations, their target genes and TFBS-TF pairs.

Genomic partitioning of growth traits using a high-density single nucleotide polymorphism array in Hanwoo (Korean cattle)

  • Park, Mi Na;Seo, Dongwon;Chung, Ki-Yong;Lee, Soo-Hyun;Chung, Yoon-Ji;Lee, Hyo-Jun;Lee, Jun-Heon;Park, Byoungho;Choi, Tae-Jeong;Lee, Seung-Hwan
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.10
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    • pp.1558-1565
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    • 2020
  • Objective: The objective of this study was to characterize the number of loci affecting growth traits and the distribution of single nucleotide polymorphism (SNP) effects on growth traits, and to understand the genetic architecture for growth traits in Hanwoo (Korean cattle) using genome-wide association study (GWAS), genomic partitioning, and hierarchical Bayesian mixture models. Methods: GWAS: A single-marker regression-based mixed model was used to test the association between SNPs and causal variants. A genotype relationship matrix was fitted as a random effect in this linear mixed model to correct the genetic structure of a sire family. Genomic restricted maximum likelihood and BayesR: A priori information included setting the fixed additive genetic variance to a pre-specified value; the first mixture component was set to zero, the second to 0.0001×σ2g, the third 0.001×σ2g, and the fourth to 0.01×σ2g. BayesR fixed a priori information was not more than 1% of the genetic variance for each of the SNPs affecting the mixed distribution. Results: The GWAS revealed common genomic regions of 2 Mb on bovine chromosome 14 (BTA14) and 3 had a moderate effect that may contain causal variants for body weight at 6, 12, 18, and 24 months. This genomic region explained approximately 10% of the variance against total additive genetic variance and body weight heritability at 12, 18, and 24 months. BayesR identified the exact genomic region containing causal SNPs on BTA14, 3, and 22. However, the genetic variance explained by each chromosome or SNP was estimated to be very small compared to the total additive genetic variance. Causal SNPs for growth trait on BTA14 explained only 0.04% to 0.5% of the genetic variance Conclusion: Segregating mutations have a moderate effect on BTA14, 3, and 19; many other loci with small effects on growth traits at different ages were also identified.