• Genomics & Informatics
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• v.7 no.2
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• pp.131-135
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• 2009

Domains are the building blocks of proteins. Exon shuffling is an important mechanism accounting for combination of a limited repertoire of protein domains in the evolution of multicellular species. A relative excess of domains encoded by symmetric exons in metazoan phyla has been presented as evidence of exon shuffling, and symmetric domains can be divided into old and new domains by determining the ages of the domains. In this report, we compare the spread, versatility, and subcellular localization of old and new domains by analyzing eight metazoan genomes and their respective annotated proteomes. We found that new domains have been expanding as multicellular organisms evolved, and this expansion was principally because of increases in class 1-1 domains amongst several classes of domain families. We also found that younger domains have been expanding in membranes and secreted proteins along with multi-cellular organism evolution. In contrast, old domains are located mainly in nuclear and cytoplasmic proteins. We conclude that the increasing mobility and versatility of new domains, in contrast to old domains, plays a significant role in metazoan evolution, facilitating the creation of secreted and transmembrane multidomain proteins unique to metazoa.

• Journal of Microbiology
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• v.35 no.1
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• pp.47-52
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• 1997

To examine whether the xylene component of BTX (benzene, toluene, xylene) mixture is cometabolized and residues are produced in soil, $\^$14/C-labeled-0-xylene was added to sandy loam in combination with unlabeled benzene and toluene. After 4 weeks of incubation in a sealed system connected to an oxygen reservoir, 55.1% of the radiocarbon was converted to $\^$14/CO$\sub$2/, 3.0% was to 95.8% radiocarbon recovery. Biomass incorporation of o-xylene radiocarbon which was detected by fumigation/extraction was usually low (5.6%), but 32.1% radiocarbon became associated with soil humus. Most of the numus-bound radiocarbon was found in humin fraction. In addition to o-xylene, p-xylene and toluene also showed similar results. The evidence shows that some of their reactive methylcatechol biodegradation intermediates attach to the humic metrix in soil in preference to mineralization and biomass incorporation.

• Clinical and Experimental Pediatrics
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• v.45 no.5
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• pp.664-668
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• 2002

A twenty six months-old boy developed hemophagocytic syndrome during the course of Kawasaki disease. Despite the appropriate treatment modalities for Kawasaki disease, he developed thrombocytopenia, hepatomegaly, high-grade fever, hypertriglyceridemia, peripheral gangrene, and evidence of hemophagocytosis in bone marrow biopsy. Although the course was stormy, he responded well to a combination therapy of corticosteroid and etoposide.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.11
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• pp.1401-1409
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• 1999

In this paper, a conceptual framework of a new concept of protectability is proposed, which indicates the protection level of the system. Evaluation attributes have been identified and a hierarchical evaluation model has been established. Dempster-Shafer Theory of Evidence is applied in combining multiple uncertain judgements to produce an aggregated evaluation.

• Proceedings of the Korean Information Science Society Conference
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• 2005.07b
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• pp.634-636
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• 2005

지능형 로봇 기술이 발전하면서 영상에서 장면을 이해하는 연구가 많은 관심을 받고 있으며, 최근에는 불확실한 환경에서도 좋은 성능을 발휘할 수 있는 확률적 접근 방법이 많이 연구되고 있다. 본 논문에서는 확률적 모델링이 가능한 베이지안 네트워크(BN)를 이용해서 장면 인식 추론 모듈을 설계하고, 실제 환경에서 얻어진 증거 및 베이지안 추론 결과를 결합하여 분류 성능을 향상시키기 위한 방법을 제안한다. 영상 정보는 시간에 대해 연속성을 가지고 있기 때문에, 증거 정보와 베이지안 추론 결과들을 적절히 결합하면 더 좋은 결과를 예상할 수 있으며, 본 논문에서는 확신 요소(Certainty Factor: CF) 분석에 의한 결합 방법을 사용하였다. 성능 평가 실험을 위해서 SET (Scale Invariant Feature Transform) 기법을 이용하여 물체 인식 처리를 수행하고, 여기서 얻어진 데이터를 베이지안 추론의 증거로 사용하였으며, 전문가의 CF 값 정의에 의한 베이지안 네트워크 설계 방법을 이용하였다.

• Journal of Korean Society of Forest Science
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• v.95 no.5
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• pp.539-542
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• 2006

This study confirmed econometrically the causality of forest inventory and roundwood supply using Korean data. In general, forest inventory is included as explanatory variable in roundwood supply function. We checked whether each series is stationary or not before using it in the model, and determined whether the combination of the series is comtegrated. The relationship between forest inventory and roundwood supply was represented by bivariate vector autoregressive model. The causality of forest evidence of the causal relationship between change in forest inventory and change in roundwood supply in Korea. That is, change in forest inventory does not cause change in roundwood supply in Korea. It seems reasonable not to include forest inventory as explanatory variable in roundwood supply function in Korea.

• Cross-Cultural Studies
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• v.32
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• pp.5-28
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• 2013

In this paper, a style-based approach to translating literary texts is introduced and used. The aim of the study is to work out a stylistic approach to translating literary texts from Arabic into English. The approach proposed in the current study is a combination of four major stylistic approaches, namely linguistic stylistics, literary stylistics, affective stylistics and cognitive stylistics. It has been shown from data analysis that by adopting a style-based approach that can draw from the four stylistic approaches, translators, as special text readers, can easily derive a better understanding and appreciation of texts, in particular literary texts. Further, it has been shown that stylistics as an approach is objective in terms of drawing evidence from the text to support the argument for the important stylistic features and their functions. However, it loses some of its objectivity and becomes dependent and subjective.

• Proceedings of the Korea Society for Simulation Conference
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• 1992.10a
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• pp.8-8
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• 1992

Through a simulation experiment, often an experimenter is concerned with estimating the system parameters of the linear model consisting of m design points from the outputs oft the simulation model. To improve the estimation of the system parameters and reliability of these estimators, appropriate simulation techniques have been developed. For the first order linear model, Schruben and Margolin (1978) exploited the random number assignment rules which uses a combination of common random numbers and antithetic streams in a simulation experiment designed to estimate the system parameters when the design matrix of simulation model admits orthogonal blocking into two blocks. Nozari, Arnold and Pegden (1984) developed a method for appliying the method of control variates to the situation of the linear model having multiple design points. This talk deals with a different way of utilizing controls under the correlation induction strategy of Schruben and Margolin's to improve the simulation efficiency, and presents a procedure for obtaining the estimators of the system parameters analytically. Simulation results on a selected simulation model indicate a promising evidence that a proposed method may yield better results than Schruben and Margolin's method.

• Journal of The Korean Society of Clinical Toxicology
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• v.6 no.2
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• pp.142-145
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• 2008

Lamotrigine is a newer anti-epileptic drug for adjunctive treatment of refractory epilepsy, partial seizures, generalized tonic-clonic seizures, and bipolar disorder. Lamotrigine overdose causes serious central nervous and cardiovascular problems, but reports are uncommon. Few lamotrigine overdoses have been described because anti-epileptic drug use is limited and usually used with combination of other anti-epileptic drugs. In addition, most patients visit emergency departments with multi-drug overdoses, so few cases of lamotrigine poisoning alone exist. We had a female patient visit our emergency department a couple of hours after a lamotrigine overdose treated with intravenous hydration and urine alkalization by NaHCO3. She recovered successfully without any evidence of renal injury. However, she developed profound rhabdomyolysis, a previously unreported complication of this medication. We suggest that serial creatine kinase levels should be measured after lamotrigine poisoning.

• Communications for Statistical Applications and Methods
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• v.28 no.6
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• pp.583-594
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• 2021

In this paper, we propose wavelet-based procedures to identify the difference between images, including portraits and handwriting. The proposed methods are based on a novel combination of multiscale methods with a regularization technique. The multiscale method extracts the local characteristics of an image, and the distinct features are obtained through the regularized regression of the local characteristics. The regularized regression approach copes with the high-dimensional problem to build the relation between the local characteristics. Lytle and Yang (2006) introduced the detection method of forged handwriting via wavelets and summary statistics. We expand the scope of their method to the general image and significantly improve the results. We demonstrate the promising empirical evidence of the proposed method through various experiments.