• Title/Summary/Keyword: Evidence Based Design

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A Study on the Build of a QbD Six Sigma System to Promote Quality Improvement(QbD) Based on Drug Design (의약품 설계 기반 품질 고도화(QbD)를 위한 QbD 6시그마 체계 구축에 관한 연구)

  • Kim, Kang Hee;Kim, Hyun-jung
    • Journal of Korean Society for Quality Management
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    • v.50 no.3
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    • pp.373-386
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    • 2022
  • Purpose: This study proposes the application of Six Sigma management innovation method for more systematically enhanced execution of Quality by Design (QbD) activities. QbD requires a deeper understanding of the product and process at the design and development stage of the drug, and it is very important to ensure that no fault is fundamentally generated through thorough process control. Methods: Analyzing the background and specific procedures of quality improvement based on the drug design basis, and analyzing the key contents of each step, we have differentated and common points from the 6 Sigma methodology. We propose a new model of Six Sigma management innovation method suitable for pharmaceutical industry. Results: Regulatory agencies are demanding results from statistical analysis as a scientific basis in developing medicines to treat human life through quality improvement activities based on drug design. By utilizing the education system to improve the statistical analysis capacity in the Six Sigma activities and operating the 6 Sigma Belt system in conjunction, it helped systematically strengthen the execution power of quality improvement activities based on pharmaceutical design based on the members of the pharmaceutical industry. Conclusion: By using QbD Six Sigma, which combines quality enhancement based on pharmaceutical design basis and Six Sigma methodology suitable for pharmaceutical industry, it is possible to obtain satisfactory results both by pharmaceutical companies and regulators by using appropriate statistical analysis methods for preparing scientific evidence data required by regulatory.

A Systematic Study on the Effect of Social StoryTM Intervention for Individual with Autism Spectrum Disorder (자폐스펙트럼장애 아동을 위한 상황이야기 중재의 효과 연구에 대한 체계적 고찰)

  • Bae, Won-Jin;Park, Ju-Young
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.2
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    • pp.131-140
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    • 2021
  • Purpose : The purpose of this study was to systematically review the studies on the effects of social story intervention on the individuals with autism spectrum disorders(ASD) to provide the basis for evidence-based practice. Methods : In order to find out the studies on the effect of social story intervention on individuals with ASD, studies published from 2011 to December 2020 were searched on Google Academic Search. The keywords used were "autism spectrum disorder AND social story". A total of 16,900 studies were searched, and from these, 12 studies were selected based on the application of the selection and exclusion criteria. The included studies comprised of 10 single subject design studies and 2 randomized controlled trials design studies. The included studies were analyzed in accordance to population, intervention, outcome measures and results. Results : As a result of analysing the subjects of the included studies, we found out that pre-school children and adolescents were the most common groups of individuals diagnozsed with ASD. In addition to ASD, the diagnosis of the subjects included intellectual disability, Asperger, and Prader-willi. We found out that there were more interventions that were mixed with other interventions, than just the pure social story interventions. In particular, video modeling was found to be the most frequent intervention. This was followed by photo-based social stories. For outcome measure, autism social skills profile was found to be the most often used standardized assessment. For a non-standardized assessment, social desired behavior was found to be the most frequently evaluated behavior, followed by personal problem behavior. Of all the dependent variables, the dependent variable reported as "effective" was the most, followed by "some effective". Conclusion : This study is organized to help the individuals with ASD, families, researchers, and therapists understand the effects of social story intervention on the individuals with ASD in an easy fashion. Further, therapists can use this study as the basic data for evidence-based practice.

A Systematic Review of Evidence for Education and Training Interventions in Microsurgery

  • Ghanem, Ali M.;Hachach-Haram, Nadine;Leung, Clement Chi Ming;Myers, Simon Richard
    • Archives of Plastic Surgery
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    • v.40 no.4
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    • pp.312-319
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    • 2013
  • Over the past decade, driven by advances in educational theory and pressures for efficiency in the clinical environment, there has been a shift in surgical education and training towards enhanced simulation training. Microsurgery is a technical skill with a steep competency learning curve on which the clinical outcome greatly depends. This paper investigates the evidence for educational and training interventions of traditional microsurgical skills courses in order to establish the best evidence practice in education and training and curriculum design. A systematic review of MEDLINE, EMBASE, and PubMed databases was performed to identify randomized control trials looking at educational and training interventions that objectively improved microsurgical skill acquisition, and these were critically appraised using the BestBETs group methodology. The databases search yielded 1,148, 1,460, and 2,277 citations respectively. These were then further limited to randomized controlled trials from which abstract reviews reduced the number to 5 relevant randomised controlled clinical trials. The best evidence supported a laboratory based low fidelity model microsurgical skills curriculum. There was strong evidence that technical skills acquired on low fidelity models transfers to improved performance on higher fidelity human cadaver models and that self directed practice leads to improved technical performance. Although there is significant paucity in the literature to support current microsurgical education and training practices, simulated training on low fidelity models in microsurgery is an effective intervention that leads to acquisition of transferable skills and improved technical performance. Further research to identify educational interventions associated with accelerated skill acquisition is required.

Do Perceived Choice Attributes in Traditional Market Influence Perceived Value, Satisfaction, and Loyalty? (전통시장의 지각된 선택속성 지각이 지각된 가치, 만족, 그리고 충성도에 미치는 영향 )

  • Yong Jae RIM;Yong Ki LEE;Jae Youl KIM
    • The Korean Journal of Franchise Management
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    • v.14 no.4
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    • pp.17-33
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    • 2023
  • Purpose: This study divides choice attributes that can help strengthen the competitiveness of traditional markets into product, price, personnel, and physical evidence. This study also examines which choice attributes affect customer value perception, satisfaction, and loyalty. Research design, data, and methodology: The data were collected from 542 traditional customers aged 20 or older who frequently visit traditional markets across the country and analyzed using the Smart PLS 4.0 program. The survey was conducted with the help of an online survey company for a total of 14 days from April 7, 2023 to April 20, 2023. Result: First, product, price, and employee quality have a positive impact on utilitarian and hedonic value, but physical evidence does not. Second, product, price, and employee quality have a positive impact on hedonic and hedonic value. Second, utilitarian value has a positive impact on satisfaction and revisit intention. Third, hedonic value has a positive impact on satisfaction, but does not on revisit intention. Lastly, satisfaction has a positive impact on revisit intention. Conclusions: Based on the S-O-R model and the theory of consumption value, this study proposed and examined an integrated framework in which satisfaction leads to revisit intention through selection attributes acting on perceived value.

The Influence of Information Retrieval Skill on Evidence Based Practice Competency in Clinical Nurses (상급 종합병원 간호사의 정보검색능력이 근거기반실무 역량에 미치는 영향)

  • Son, Youn-Jung;Kim, Sun-Hee;Park, Young-Su;Lee, Soo-Kyoung;Lee, Yun-Mi
    • Korean Journal of Adult Nursing
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    • v.24 no.6
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    • pp.635-646
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    • 2012
  • Purpose: The purpose of this study was to understand clinical nurses' level of information retrieval skill and its influence on evidence based practice (EBP). Methods: A cross-sectional design was used. Data were collected from a convenient sample of 492 nurses working at 5 university hospitals in Korea. The Data were analyzed using descriptive statistics, t-test, one-way ANOVA, and hierarchical multiple linear regression. Results: The mean score for information retrieval skill and EBP competency were respectively $2.81{\pm}0.64$ and $3.98{\pm}0.86$. Two step hierarchical regression analysis showed that attendance at academic conference (p = .036) and information retrieval skill (p<.001) were significant factors of EBP competency, information retrieval skill explained about 19% of total variance of EBP competency. Conclusion: Nurse need to increased fundamental information retrieval skill for EBP competency. Therefore, it is important to increase nurses' information retrieval skills by tailoring continuing EBP education modules. It would be also advisable to develop centralized systems for the internal dissemination of research findings for the use of nursing staff.

Factors Influencing Evidence-Based Practice Readiness for Tertiary General Hospital Nurses (상급 종합병원 간호사의 근거기반실무 준비도에 대한 영향요인)

  • Kim, Jeong-Sook;Gu, Mee-Ock;Jo, Sun-Yon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.6
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    • pp.2945-2957
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    • 2013
  • This study was conducted to investigate factors contributing to Evidence-Based Practice Readiness(Knowledge/Skill, Attitudes, Organizational culture) for nurses. A descriptive correlational study design was used. The data were collected from Mar. 21 to Mar. 29 of 2013. The subject were 160 nurses who were working in the 2 Tertiary General Hospital. Factors influencing EBP Knowledge/Skill were critical thinking disposition, which explained about 34.7% of total variance. and EBP Attitudes were EBP Knowledge/Skill, surgical unit, Which explained about 14.2% of total variance. and Organizational culture for EBP were Innovation-oriented culture, Relational-oriented culture, Which explained about 24.6% of total variance. Therefore, For introduction and activated of EBP, Nursing organization-dimentional required at the critical thinking disposition and EBP Knowledge/Skill training programs development and to be applied. Also, Systematic support system for the nursing organization to create a culture of Innovation-oriented culture is required.

Development and effects of a nursing information literacy competency education program for undergraduate nursing students (간호대학생을 위한 간호정보활용역량 교육프로그램 개발 및 효과 검증)

  • Jo, Mean Jung;Gu, Mee Ock
    • The Journal of Korean Academic Society of Nursing Education
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    • v.27 no.2
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    • pp.210-222
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    • 2021
  • Purpose: This study was conducted to develop and test the effects of a nursing information literacy competency education program for undergraduate nursing students. Methods: A non-equivalent control group pretest-posttest design was used. The subjects consisted of 42 sophomore undergraduate nursing students who had completed a fundamental nursing course (experimental group: n=21, control group n=21). The nursing information literacy competency education program consisted of 8 steps in 8 sessions, taught over 4 weeks, which was 20 hours in total. Data were collected between January 23 and March 14, 2019 and were analyzed using Chi-square test, Fisher's exact test, t-test, paired t-test, and repeated measure ANOVA with SPSS/WIN 23.0. Results: Significant differences were shown between the experimental and control groups regarding nursing information literacy competency (F=91.74, p<.001), problem-solving ability (F=52.43, p<.001), self-directed learning ability (F=36.61, p<.001), and evidence-based practice competency (F=59.66, p<.001). Conclusion: The nursing information literacy competency education program was effective in improving the nursing information literacy competency, problem-solving ability, self-directed learning ability, and evidence-based practice competency of nursing students. Hence, we recommend the nursing information literacy education program will be included as an independent course in the nursing curriculum for undergraduate nursing students to promote a needed proficiency in nursing information literacy competency.

Trends in Health Education and Promotion Research Published in the Korean Journal of Health Education and Promotion from 2009 to 2011 (최근 보건교육건강증진학회지 게재논문 동향 (2009-2011년))

  • Kim, Hye-Kyeong;Kwon, Eun-Joo
    • Korean Journal of Health Education and Promotion
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    • v.29 no.4
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    • pp.1-13
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    • 2012
  • Objectives: By analysing the recent trends of published papers in the Korean Journal of Health Education and Promotion, this study aims to identify and discuss some challenging issues, and to provide recommendations for quality improvement of the research papers. Methods: One hundred and sixty five papers published between 2009 and 2011 were examined and categorized according to selected standards. Results are displayed in frequencies and percentages. Results: The volume of articles published has increased by two-folds in three decades since the publication of the first issue. More than 90% of the papers were original articles. Cross-sectional research design was most frequently applied, while only 11.5 % of the articles were intervention studies. For cross-sectional research articles, limitation in generalizability of the study findings was mentioned as one of the major issues, in relation with the frequent use of convenient sampling methods and lack of theoretical evidence in inclusion of variables. Consideration of internal and external validity of the study, utilization of scientific evaluation design and mixed evaluation methods were recommended for intervention research to improve the quality of the research results. Conclusion: To serve as a key resource for evidence-based practices in health promotion, more strict scientific research criteria should be applied to the articles published in the Korean Journal of Health Education and Promotion.

An Analysis of the Healing Effects by Types of Forest Space - Focused on Psychological Restorativeness and Satisfaction - (숲 공간유형별 특성에 따른 치유효과 분석 - 심리적 회복감과 만족도를 중심으로 -)

  • Park, Sun-A;Lee, Myungwoo
    • Journal of the Korean Institute of Landscape Architecture
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    • v.44 no.4
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    • pp.75-85
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    • 2016
  • In recent years, natural healing space studies have been done in health care and forestry. However, previous studies have focused on healing effects of natural elements in interior space or natural landscape view. And there is a limit to using the evidence for healing space design. The aim of this study is to discover the relationship between types and effects of healing space for evidence-based design. This study compares and analyzes the mayor images, psychological restorativeness, and satisfaction to identify the effects and differences of natural trail, designed trail, natural shelter, and designed shelter by types of forest space. Collected data is analyzed with a factorial analysis, valiance analysis and multiple regression analysis in SPSS 18.0. The results of this study are as follows: 1) Among five factors consisting psychological restorativeness, natural trail can be achieved with 'being away' and 'compatibility' and designed shelter can be achieved with 'fascination' and 'coherence'., 2) Psychological restorativeness values higher in images with higher excitement, brightness, vitality, and beautifulness as well as in images with lower level of disorder., 3) Among five factors consisting psychological restorativeness, higher forest satisfaction can be achieved with a higher level of 'being away' and 'coherence'. In conclusion, this study contributes to providing fundamental information for design guidelines of healing spaces through identifying the characteristics of healing environment by types of forest space.

The effect of motor learning in children with cerebral palsy: A systemic review (뇌성마비 아동의 운동학습 효과 체계적 고찰)

  • Kim, Jung-Hyun
    • Journal of Korean Physical Therapy Science
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    • v.28 no.1
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    • pp.33-45
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    • 2021
  • Background: Children with cerebral palsy have difficulty acquiring motor skills through motor learning due to lack of motor planning of the central nervous system and musculoskeletal dysfunction. Motor learning is the acquisition or modification of movements with the aim of developing skilled movements and behaviors. Cerebral palsy improve motor function through motor learning, and effective motor learning mainly depends on practice parameters such as learning feedback. Therefore, we investigate the effect of motor learning in children with cerebral palsy and try to present the possibility of clinical application. Design: A systemic review. Methods: Research papers were published from Jan, 2010 to Dec, 2020 and were searched using PubMed and Medline. The search terms are 'task specific training' OR 'motor learning' OR 'feedback(Mesh term)' OR 'goal activity' AND 'cerebral palsy(Mesh term)'. A total of eight papers were analyzed in this study. The paper presented the quality level based on the research evidence, and also presented PEDro (Physiotherapy Evidence Database) scores to evaluate the quality of design studies in randomized clinical trials. Results: The results showed that motor learning coaching in children with cerebral palsy improved motor function in post and follow up tests. Also, self-control feedback of motor learning is more effective than external control feedback. 100% external control feedback of motor learning is effective in the acquisition phase and 50% external feedback of motor learning is effective in the retain phase. Conclusion: These results suggest that it will be an important data for establishing evidence on the effect of motor learning arbitration methods in children with cerebral palsy to develop clinical applicability and protocols.