• Annals of Clinical Neurophysiology
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• v.3 no.2
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• pp.136-142
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• 2001

Background : Nervous system dysfunction is a major complication of end stage renal disease. Although severe neurologic symptoms are partially or completely reversed by adequate hemodialysis, even optimally dialyzed patients will usually not return to normal neurocognitive function. To investigate the influence of chronic renal failure and hemodialysis on higher cognitive function electrophysiologically, we studied auditory P300 event-related potentials in 14 hemodialysis patients and 14 age- and sex-matched normal healthy controls. Methods : The subjects consisted of 14 patients(M: 6, F: 8) with chronic renal failure(CRF) for 1 to 10 years and 14 age- and sex-matched healthy controls(M: 5, F: 9). For the reliability of study, patients with diabetes mellitus, abnormal brain CT findings, or low mini-mental state score(below 20) were excluded. Event related potentials(ERPs) for hemodialysis patients were performed at pre- and post-hemodialysis. To obtain ERPs, subjects underwent 2-tone auditory discrimination test(oddball paradigm). Results : Although the age(control: $48.79{\pm}10.31years$, CRF: $51.21{\pm}7.61years$) and mini-mental state score(control: $27.00{\pm}1.71points$, predialysis CRF: $25.07{\pm}3.58points$) were not different in normal control and CRF groups significantly(P>0.05), P300 latencies at Cz(control: $288.11{\pm}17.36msec$, predialysis CRF: $332.35{\pm}42.34msec$) were significantly delayed(P<0.05)and the duration of Trail making test A was significantly prolonged(control: $64.2{\pm}24.2sec$, CRF: $118.9{\pm}101sec$) in CRF group. P300 latencies between pre- and post-hemodialysis CRF patients(predialysis CRF: $332.35{\pm}42.34msec$, postdialysis CRF: $325.82{\pm}38.69msec$) were not significantly different. The P300 latency was not related with the duration of CRF(Spearman's correlation test, r=0.25, P>0.05) and the frequency of hemodialysis(Spearman's correlation test, r=0.28, P>0.05). Conclusions : From these results, we suggest that P300 latency is valuable in evaluating cognitive brain dysfunction in patients with CRF and hemodialysis does not have a significant effect on cognitive brain dysfunction in patients with CRF.

• Journal of the Korean Institute of Intelligent Systems
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• v.20 no.3
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• pp.388-393
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• 2010

Cultural Content Technology(CT, Culture Technology) for the development of cultural industry and the commercialization of technology, cultural contents, media, mount, pass the value chain process and increase the added value of cultural products that are good for all forms of intangible technology. In the field of Culture Technology, Music by analyzing the characteristics of the development of a variety of applications has been studied. Associated with EEG measures and the results of their research in response to musical stimuli are used to detect and study is getting attention. In this paper, the musical stimuli in EEG signals by amplifying the corresponding reaction to the averaging method, ERP (Event-Related Potentials) experiments based on the process of extracting sound methods for removing noise from the ICA algorithm to extract the tone and noise removal according to the results are applied to analyze the characteristics of EEG.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.2
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• pp.131-138
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• 2020

Purpose : The purpose of this study was to investigate the effects of the frequency band pass filter on the P300 event-related potential in the working memory. Methods : The subjects were 20 women in their 20s who applied for participation in the experiment. Event-related potentials (ERPs) were elicited using 3-back tasks for the working memory, and were recorded from Fz, Cz, and Pz scalp electrodes. The high-pass filters were set to 0.01, 0.1, and 0.3 Hz for analysis purposes, and the low-pass filters were set to 30 and 15 Hz. The 3-back task was presented for a total of 100 times, among which 30 times were designated for the target stimulation (a matched number) and 70 times for the non-target stimulation (an unmatched number). The temporal interval between each stimulation was set at 1 second, while each time duration was randomly presented between 2 to 4 seconds. ERP were analyzed for the P300 recorded from Fz, Pz and Cz scalp electrodes. Results : Latency and amplitude had no significant interaction effects in both the high- and low-pass filters. For the main effects, the latency and amplitude of the P300 event-related potential had no significant difference in the high-pass filters, but the latency had a significant difference in the low-pass filter of Fz, and the amplitude had a significant difference in the low-pass filter of Pz. Conclusion : The results of this study showed that the less than 0.3 Hz high filters had no effects on the differences between the latency and amplitude of the P300 event-related potential in the working memory. The 30Hz low-pass filter, however, was found to be useful for recording the P300 event-related potential in the working memory.

• Phonetics and Speech Sciences
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• v.2 no.4
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• pp.3-10
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• 2010

The present study aims to investigate neural activations according to the level of code switching in English proficient bilinguals and to find the relationship between the performance of language switching and proficiency level using ERPs (event-related potentials). First, when comparing high-proficient (HP) with low-proficient (LP) bilingual performance in a native language environment, the activation level of N2 was observed to be higher in the HP group than in the LP group, but only under two conditions: 1) the language switching (between-language) condition known as indexing attention of code switching and 2) the inhibition of current language for L1. Another effect of N400 can be shown in both groups only in the language non-switching (within-language) condition. This effect suggests that both groups completed the semantic acceptability task well in their native language environment without the burden of language switching, irrespective of high or low performance. The latencies of N400 are only about 100ms earlier in the HP group than in the LP group. This difference can be interpreted as facilitation of the given task. These results suggest that HP showed the differential activation in inhibitory system for L1 in switching condition of L1-to-L2 to be contrary to inactivation of inhibitory system for the LP group. Despite the absence of an N400 effect at the given task in both groups, differential latencies between the peaks were attributed to the differences of efficiency in semantic processing.

• Journal of Biomedical Engineering Research
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• v.23 no.4
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• pp.301-308
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• 2002

This research was performed to analyze quantitatively how spiritual stress affects some ERPs on human through sight stimulus after the settlement of visual and auditory integration environment in three dimension space. We measured ERPs in the normal state and spiritual stress sessions separately. The subjects were 10 normal men and women and vital signs was recorded from Fpl, Fz, Cz, Pz, O1, O2's scalps. The experiment was done in isolated room where electro-magnetic effect do not affect. The result showed that P300's amplitude was a little higher under stress session and latent period in this resulted in longer time. We recorded through voltage variation the activity of brain which is in charge of human's perception. cognition, process of action and evaluated the effect of spiritual stress. We expected that the result of this research can be used to evaluate the malfunction of brain.

• Annual Conference on Human and Language Technology
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• 2004.10d
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• pp.259-263
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• 2004

본 연구는 머리어-후행언어(head-final language)로 분류되는 한국어의 통사 및 의미 처리 과정의 언어간(cross linguistic) 일반성과 언어내(intra-language) 특이성을 ERP(event- related potentials) 실험결과를 통해 알아보고자 하였다. 한국어 문장처리 과정에서의 통사 및 의미 처리특성은, 우선 이들을 지표하는 각각의 오류문을 통해 P600과 N400 이라는 언어일반의 처리과정을 보이면서도 각 성분의 영역분포는 오류가 출현된 위치에 따라 분기하고 있음을 관찰할 수 있었다. 곧, 문미위치의 술어오류에서 중심-두정 부위의 활성화 우세로 각 오류간 영역분화를 보이는 패턴을 새롭게 확인하였다. 이로써 오류의 유형별 재분류과정으로 드러난 오류출현 위치가 오류의 유형 내에 영향을 끼치는 한 변수가 될 수 있으며. 이는 이들 보어 및 술어를 구성하는 고유의 범주 특성으로 해석할 수 있는 근거가 될 수 있음도 아울러 확인하였다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.2
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• pp.689-695
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• 2010

The effect of the code conversion process of Korean script (Hangul), also known as words for numbers, was investigated using event-related potentials (ERPs) during mental arithmetic operations. Study subjects were asked to determine whether the arithmetic results of a given target stimuli were correctly matched. Visual inspection and statistics of mean ERPs showed stimulus type-dependent processing rather than task-dependent processing. Results of addition and multiplication tasks revealed that the overall temporal profiles of the Arabic numerals were similar to the Hangul words for numbers. The only exception to this observation was a delayed positive-slope peak occurring around 300 ms, which was likely related to the encoding process of Hangul words for numbers to Arabic-digits, defined as a 'transcoding-related potential.' Source analysis confirmed that the topography of different waveforms for the two conditions was attributed to a single dipole located in the left temporo-parietal area; this area is known to be involved in Hangul words for number processing. These results suggest that the initial processing for encoding words for numbers was followed by arithmetic operations without direct access of internal number representation. Korea Academia-Industrial cooperation Society. The Korea Academia-Industrial cooperation Society. The Korea Academia-Industrial cooperation Society. The Korea Academia-Industrial cooperation Society.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.5003-5011
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• 2013

This paper measured whether neural and behavior responses to attention-emotion task were reflected to emotion regulation capacities. For this purpose, Nineteen healthy right-handed graduates participated in the emotion-attention task three times for three days. Before and after the negative and positive video clips were shown, the participants performed emotion-attention task. EEG and response time were recorded during emotion-attention task. There was positive correlation between ERP P100 and P300 component. The larger the P100 amplitudes at the specific positions, the longer the P300 latencies at these same positions during attention-emotion task. The longer the P300 latencies at the specific positions, the longer the delay in response time. Also, there is and individual differences in ERP components and response time during attention-emotion integration task. Individuals who had lower amplitude and shorter latency of ERP showed faster response time during attention-emotion task, regardless of the type of video clips. This characteristic was interpreted to the lower emotional controls due to premature response for target identification.

• Science of Emotion and Sensibility
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• v.20 no.2
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• pp.149-160
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• 2017

In hypothesis testing, the interpretation of a statistic obtained from the data analysis relies on a probabilistic distribution of the statistic constructed according to several statistical theories. For instance, the statistical significance of a mean difference between experimental conditions is determined according to a probabilistic distribution of the mean differences (e.g., Student's t) constructed under several theoretical assumptions for population characteristics. The present study explored the logic and advantages of random-resampling approach for analyzing event-related potentials (ERPs) where a hypothesis is tested according to the distribution of empirical statistics that is constructed based on randomly resampled dataset of real measures rather than a theoretical distribution of the statistics. To motivate ERP researchers' understanding of the random-resampling approach, the present study further introduced a specific example of data analyses where a random-permutation procedure was applied according to the random-resampling principle, as well as discussing several cautions ahead of its practical application to ERP data analyses.

• Korean Journal of Cognitive Science
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• v.20 no.2
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• pp.155-181
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• 2009

Psychophysiologists are often interested in the EEG signals that accompany certain psychological events. When one is interested in a time series of event-related changes in EEG, one focuses on examining how the waveforms recorded at individual electrode sites vary over time across one or more experimental conditions. This is an analysis of event-related potentials (ERPs). In addition to such a classical EEG analysis in the time domain, the EEG measures can be investigated in the frequency domain. Moreover, it has been demonstrated that spectral analyses can often yield significant insight into the functional cognitive correlations of the signals. Therefore, this review paper tries to summarize essential concepts (e.g. phase-locking) and conventional methods (e.g. wavelet transformation) for understanding spectral analyses of brain oscillatory activity. Phase-coherence is also introduced in relation to functional connectivity of the brain.