• 한국수자원학회논문집
• /
• 제37권2호
• /
• pp.133-144
• /
• 2004

토양수분 저류구조를 갖는 4단 탱크모형에 SCE-UA전역최적화 기법을 사용하여 목적함수에 따라 보정자료 기간을 달리하여 대청댐 유역에 332회, 소양강댐 유역에 대해 472회의 보정 및 검증을 수행하였다. 그리고 증발산량 산정방법에 따른 매개변수 추정 영향을 검토하기 위해 소형 증발계 증발량, 1963 Penman, FAO-24 Penman-Monteith, FAO-56 Penman-Monteith 방법을 사용하였다. 토양수분 저류구조를 갖는 탱크모형은 표준 4단 모형보다 우수한 결과를 나타내었다. 토양수분 저류구조를 갖는 탱크모형의 매개변수 추정에 적합한 목적함수 두 가지를 확인하였다. 매개변수 추정을 위해 적절한 자료기간은 3년 정도이었으며, 평균강수량 이상인 해와 가물었던 해를 포함하는 것이좋은 결과를 보였다. 그리고 유출률이 적절하지 않은 해를 포함하는 경우에는 8년 이상으로 하는 것이 적절하다고 판단된다. 4가지 증발산량 산정 방법에 의해 추정된 증발산량을 입력으로 모형을 보정한 결과 유사한 매개변수를 나타내었으며, 1963 Penman 방법만이 근소하게 열등하였다.

• 한국분무공학회지
• /
• 제17권3호
• /
• pp.113-120
• /
• 2012

It is being more serious problems that the pollutant and the greenhouse gas emitted from the internal combustion engines due to the increasing demand of automobiles. To counteract this, as one of the ways has been studied, GDI type engine, which is directly injected into the combustion chamber and burns by a spark ignition that chose the merits of both gasoline engine and diesel engine, was appeared. The combustion phenomena in this GDI engine is known to contribute to combustion stability, fuel consumption reduction and reductions of harmful substances of exhaust gas emission, when the fuel spray of atomization being favorable and the mixture formation being promoted. Accordingly, this study analyzed the affection of ambient temperature and fuel injection pressure to the fuel by investigate the visualization of combustion, combustion pressure and the characteristic of emission, by applying GDI system on the constant combustion chamber. As a result, as the fuel injection pressure increases, the fuel distribution in the combustion chamber becomes uniform due to the increase of penetration and atomization. And when ambient temperatures in the combustion chamber become increase, the fuel evaporation rate being high but the penetration was reduced due to the reduction of volume flux, and confirmed that the optimized fuel injection strategy is highly needed.

• Bulletin of the Korean Chemical Society
• /
• 제32권3호
• /
• pp.867-872
• /
• 2011

For the prolonged delivery and sustained release rates of low molecular weight drugs, poly(lactic-co-glycolic acid) (PLGA) microparticles containing the drug SKL-2020 have been investigated. On increasing polyvinyl alcohol (PVA) concentration (from 0.2% to 5%), the size of microparticles decreased (from $48.02{\mu}m$ to $10.63{\mu}m$) and more uniform size distribution was noticeable due to the powerful emulsifying ability of PVA. A higher drug loading (from 5% to 20%) caused a larger concentration gradient between 2 phases at the polymer precipitation step; this resulted in decreased encapsulation efficiency (from 34.19% to 25.67%) and a greater initial burst (from 61.71% to 70.05%). SKL-2020-loaded PLGA microparticles prepared with different fabrication conditions exhibited unique release patterns of SKL-2020. High PVA concentration and high drug loading led to an initial burst effect by rapid drug diffusion through the polymer matrix. Since PLGA microparticles enabled the slow release of SKL-2020 over 1 week in vitro and in vivo, more convenient and comfortable treatment could be facilitated with less frequent administration. It is feasible to design a release profile by mixing microparticles that were prepared with different fabrication conditions. By this method, the initial burst could be repressed properly and drug release rate could decrease.

• Journal of Advanced Marine Engineering and Technology
• /
• 제32권4호
• /
• pp.534-541
• /
• 2008

This paper deals with the heat transfer characteristics of R-290 (Propane), R-600a (Iso-butane) and R-1270 (Propylene) as an environment friendly refrigerant and R-22 as a HCFC's refrigerant for evaporating. The experimental apparatus has been set-up as conventional vapor compression type refrigeration and air-conditioning system. The test section is a horizontal double pipe heat exchanger. Evaporating heat transfer measurements were performed for smooth tube with the outer diameters of 12.70, 9.52 and 6.35 mm and micro-fin tube 12.70 mm, respectively. For the smooth and micro-fin tubes measured in this study, the evaporating heat transfer coefficient was enhanced according to the increase of the mass flux and decrease of the tube diameter. The local evaporating heat transfer coefficients of hydrocarbon refrigerants were superior to those of R-22 and the maximum increasing rate of heat transfer coefficient was found in R-1270. The average evaporating heat transfer coefficients in hydrocarbon refrigerants showed 20 to 28% higher values than those of R-22. Also, the evaporating heat transfer coefficients of R-22 in the tube diameter of the 12.70 mm smooth and micro-fin tube were compared. Generally, the local heat transfer coefficients for both types of tubes increased with an increase of the mass flux. The heat transfer enhancement factor (EF) between smooth and micro-fin tube varied from 1.9 to 2.7 in all experimental conditions.

• 한국결정학회지
• /
• 제9권1호
• /
• pp.30-38
• /
• 1998

주파수 무게센서를 장착한 자동직경제어 방식에 의해 Bi12GeO20 단결정을 쵸크랄스키법으로 육성하였다. 회전속도에 따른 계면모양의 변화를 관찰하기 위해, 회전속도를 변화시키면서 육성한 결과, 23-21rpm에서 평평한 계면이 형성되었다. Bi2O3의 휘발에 의한 화학 양론적 조성으로부터 이탈에 따른 Bi4Ge3O12의 생성과 이로 인한 색 변화를 관찰하기 위해, Bi2O3의 함량을 0.1-1mol% 보충한 결과, 0.3mol% 증발 보상을 하였을 때, 내포물이 적은 연한 갈색의 광학용 단결정을 육성할 수 있었다. 이러한 성장조건 하에서 직경 25mm x 길이 70mm 인 거의 일정한 직경을 갖는 단결정이 육성되었고 결함밀도는 103개/cm2를 나타내었다. XRD및 TEM에 의해 단결정의 우선 성장방향을 측정한 결과<110>이었다.

• KSBB Journal
• /
• 제20권1호
• /
• pp.46-49
• /
• 2005

생분해성인 curdlan을 아세틸화하여 소수성 약물인 IND의 치료효과를 증진시킬 수 있는 약물전달시스템 개발을 위한 실험을 수행한 결과, IND가 포함된 CAMs를 제조할 수 있었고, IND의 loading efficiency는 $58.44\%$였다. 약물 방출 거동에 영향을 미치는 요인 중 제조한 CAMs의 swelling 특성은 처음 1시간 동안 pH 1.4에서는 아무런 변화가 없었고 PH 7.4에서는 $30\%$의 swelling을 보였고 pH 1.4에서보다 pH 7.4에서의 swelling이 약 3배 높았다. 또한 CAMs로부터 IND의 방출은 pH 1.4에서보다 pH 7.4에서 약 15배 이상 증가하였다. 이러한 결과로 CAMs는 IND의 약물전달시스템으로 유용할 것이며 특히 pH에 의존하는 약물방출 경향을 보였다.

• 한국표면공학회:학술대회논문집
• /
• 한국표면공학회 2001년도 추계학술발표회 초록집
• /
• pp.35-35
• /
• 2001

agnesium Oxide (MgO) with a NaCI structure is well known to exhibit high secondary electron emission, excellent high temperature chemical stability, high thermal conductance and electrical insulating properties. For these reason MgO films have been widely used for a buffer layer of high $T_c$ superconducting and a protective layer for AC-plasma display panels to improve discharge characteristics and panel lifetime. Up to now MgO films have been synthesized by lE-beam evaporation, Molecular Beam Epitaxy (MBE) and Metalorganic Chemical Vapor Deposition (MOCVD), however there have been some limitations such as low film density and micro-cracks in films. Therefore magnetron sputtering process were emerged as predominant method to synthesis high density MgO films. In previous works, we designed and manufactured unbalanced magnetron source with high power density for the deposition of high quality MgO films. The magnetron discharges were sustained at the pressure of O.lmtorr with power density of $110W/\textrm{cm}^2$ and the maximum deposition rate was measured at $2.8\mu\textrm{m}/min$ for Cu films. In this study, the syntheses of MgO films were carried out by unbalanced magnetron sputtering with various $O_2$ partial pressure and specially target power densities, duty cycles and frequency using pulsed DC power supply. And also we investigated the plasma states with various $O_2$ partial pressure and pulsed DC conditions by Optical Emission Spectroscopy (OES). In order to confirm the relationships between plasma states and film properties such as microstructure and secondary electron emission coefficient were analyzed by X-Ray Diffraction(XRD), Transmission Electron Microscopy(TEM) and ${\gamma}-Focused$ Ion Beam (${\gamma}-FIB$).

• Journal of Pharmaceutical Investigation
• /
• 제38권2호
• /
• pp.99-104
• /
• 2008

PLGA micro/nano particles encapsulating ranitidine as a hydrophilic model drug were prepared by the double-emulsion solvent evaporation method. Surface morphology investigation by scanning electron microscope (SEM) showed that the emulsification by sonication could produce nanoparticles, whereas microparticles were prepared using high speed homogenizer. Moreover, while nanohalf-shell structure instead of spherical nanoparticle could be produced by adding poloxamer into oil phase (MC) with PLGA 504H, the addition of poloxamer didn't change particle shape in case of PLGA 502H. On the other hand, microparticle with poloxamer had more surface pores than those without poloxamer. The size and polydispersity (PDI) of particles were determined by particle size analyzer. Effective diameters of particles were in the range of $400{\sim}800\;nm$ and $1200{\sim}3300\;nm$ in case of nanoparticles and microparticles, respectively. Encapsulation efficiencies were in the range of $1.2{\sim}2.9%$. The addition of poloxamer produced the particles with higher encapsulation efficiency. In vitro release study in phosphate buffer (pH 7.4) at $37^{\circ}C$ showed common large initial burst release. However, the relative slower release profile could be observed in case of microparticles. Poloxamer addition increased the release rate, which was thought to be related to the increased surface area of particles.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 2006년도 하계학술대회 논문집 Vol.7
• /
• pp.169-170
• /
• 2006

In this study, ultra thin films of ferroelectric vinylidene fluoride-trifluoroethylene (VF2-TrFE) copolymer were fabricated on degenerated Si (n+, $0.002\;{\Omega}{\cdot}cm$) using by spin coating method. A 1~5 wt% diluted solution of purified vinylidene fluoride-trifluoroethylene (VF2:TrFE=70:30) in a dimethylformamide (DMF) solvent were prepared and deposited on silicon wafers at a spin rate of 2000~5000rpm for 30 seconds. After annealing in a vacuum ambient at $200^{\circ}C$ for 60 min, upper gold electrodes were deposited by vacuum evaporation for electrical measurement. X-ray diffraction results showed that the VF2-TrFE films on Si substrates had $\beta$-phase of copolymer structures. The capacitance on $n^+$-Si(100) wafer showed hysteresis behavior like a butterfly shape and this result indicates clearly that the dielectric films have ferroelectric properties. The typical measured remnant polarization (2Pr) and coercive filed (EC) values measured using a computer controlled a RT-66A standardized ferroelectric test system (Radiant Technologies) were about $0.54\;C/cm^2$ and 172 kV/cm, respectively, in an applied electric field of ${\pm}0.75\;MV/cm$.

• Nuclear Engineering and Technology
• /
• 제27권4호
• /
• pp.503-517
• /
• 1995

강제대류 천이비등 열유속을 보다 실제 적으로 예측하기 위한 역학적 모델을 개발하였다. 이 모델은 가열된 벽면 근처를 어떤 기포기둥(Vapor Blanket)이 통과할 때 일어나는 다단계 비등과정 즉, 임계 기포기둥의 형성, 기포기둥밑의 미소액막(Macrolayer)의 기화 및 고갈, 그리고 얇은 기체막에서 일어나는 불안정한 막비등과정에 기초하였다. 핵비등이탈점 (DNB )과 막비등이탈점 (DFB)사이의 천이비등 곡선상의 열유속은 임계 기포기둥이 주어진 벽면을 통과할 동안 상기한 각 비등과정의 지속 시간비(Time Fraction)를 각 비등열유속에 곱한 후 그것을 합하여 정량화하였다. 이 모델의 예측치를 현재까지 발표된 문헌들에 나타난 실험치와 비교한 결과, 본 모델은 저건도 및 10 bar 근처의 고압조건의 실험치를 잘예측하는 것으로 나타났다.