• Title/Summary/Keyword: Evans

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Evans' Syndrome Induced by Rabies Vaccination in a Dog

  • Yeji Kim;Jihyun Kim;Yunji Song;Songju Oh;Ha-Jung Kim
    • Journal of Veterinary Clinics
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    • v.40 no.4
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    • pp.288-293
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    • 2023
  • A 11-year-old neutered male Maltese dog was vaccinated with a rabies vaccine (Rabisin®, Boehringer Ingelheim International GmbH, Germany) subcutaneously at a local animal hospital. One hour after vaccination, purpura with edema was observed at the injection site and severe thrombocytopenia (0 K/μL) was noted on a complete blood count (CBC). No specific findings were found in serum chemistry, electrolyte, blood gas analysis, and coagulation tests. The patient was hospitalized and administered antihemorrhagic agents (vitamin K, desmopressin), antihistamines (chlorpheniramine) and corticosteroids (methylprednisolone sodium succinate). On a repeat CBC, mild anemia had developed, thrombocytopenia was still noted, and autoagglutination was observed on a saline agglutination test (SAT). A polymerase chain reaction panel for infectious agents (e.g., Babesia spp.) was negative. The diagnosis was secondary immune-mediated thrombocytopenia (IMT) with immune-mediated hemolytic anemia (IMHA) associated with vaccination. Therefore, the immunosuppressants (prednisolone, and mycophenolate mofetil) were administered. Six days after drug administration, new lesion was not observed, and the previous lesions were significantly improved. It gradually improved and 4 weeks after hematocrit and platelet recovered to normal levels. It was maintained for 6 months without recurrence of related symptoms. Based on patient's history and test results, the patient was diagnosed with Evans' syndrome associated with rabies vaccine.

Antihistamine Effects of Triprolidine from the Transdermal Administration of the TPX Matrix in Rats

  • Shin Sang-Chul;Choi Jun-Shik
    • Archives of Pharmacal Research
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    • v.28 no.1
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    • pp.111-114
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    • 2005
  • The antihistamine effects of the triprolidine were studied in rats to determine the feasibility of their enhanced transdermal delivery from the poly (4-methyl-1-pentene) (TPX) matrix system containing penetration enhancer and plasticizer. The antihistamine effects were determined by the Evans blue dye procedure by comparing the changes in vascular permeability increase following the transdermal administration. The vascular permeability increase was significantly reduced by transdermal administration of the triprolidine-TPX system containing triethyl citrate (TEC) and polyoxyethylene-2-oleyl ether (POE). Both the plasticizer and penetration enhancer played an important role in the skin permeation of triprolidine and increased the antihistamine effects. These results showed that the triprolidine-TPX matrix system containing plasticizer and penetration enhancer could be a transdermal delivery system providing the increased antihistamine effects.

Operative Treatment of Adult Flexible Flatfoot with Young's Tenosuspension -Case Report- (Young의 건체공술을 이용한 성인의 유연성 편평족의 수술적 치료 -증례보고-)

  • Kim, Byung-Cheol;Choi, Sung-Jong;Yoo, Chong-Il;Eun, Il-Soo;Kim, Jong-Kyun
    • Journal of Korean Foot and Ankle Society
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    • v.9 no.1
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    • pp.110-112
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    • 2005
  • We present the case of an adult flexible flatfoot that was managed with dynamic and multiplarnar approaches which consist of Young's tenosuspension, Evans osteotomy, posterior tibialis tendon advancement with flexor digitorum longus tendon transfer and Lapidus procedure.

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Introduction of a New Chiral Oxazolidin-2-one Derived from D-Mannitol and Its Applications as a Chiral Auxiliary

  • Kim, Si-Min;Jin, Hyun-Yong;Jun, Jong-Gab
    • Bulletin of the Korean Chemical Society
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    • v.23 no.5
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    • pp.749-757
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    • 2002
  • Chiral oxazolidin-2-one is easily prepared from D-mannitol and demonstrated to undergo highly diastereoselective alkylation reactions via lithium imide Z-enolates of its N-acyl derivatives to afford ${\alpha}-branched$ products. Evans syn and non-Evans sy n aldol products were also selectively obtained using this new auxiliary in high diastereomeric purity by simply changing the stoichiometry of TiCl4 and the nature of the amine base. Also, this new auxiliary is employed in diastereoselective Staudinger-type ${\beta}-lactam$ syntheses. Using 2-chloro-1-methylpyridinium iodide as the dehydrating agent, the reaction of auxiliary tethered acetic acid with trans imines gave the desired ${\beta}-lactams$ with cis-selectivity.

A LIST OF HEPATICAE COLLECTED IN THE CRATER OF MT. HANLA, WITH 6 NEW ADDITIONS TO THE KOREAN FLORA (말기녹종을 포함한 한나산화구벽의 태류)

  • Hong, Won-Shic;Kim, Byong-Tak
    • Journal of Plant Biology
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    • v.4 no.1
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    • pp.13-15
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    • 1961
  • 1. This study was made on the flora of Hepaticae in the crater of Mt. Hanla ($33^{\circ}$20' N. Lat. $126^{\circ}$4' E. Long), Isl. Quelpart. 2. the total fo the occurring species of the crater are twelve, out of which the following 6 species are new to the Korean flora. (1) Bazzania tricrenata (Wahlenb.) Trev. (2) Plagiochila satoi Hatt. (3) Scapania ampliata St. (4) Radula boryana (Web.) Nees. (5) Cololejeunea kodamae Kamimura. (6) C. macounii (Spruce) Evans. 3. The hepaticae flora of the crater consists of the following elements: Holarctic element. 4 species (33%), East Asiatic element. 2. species (16%), Korean-Japan element. 5. species (41%), North-Pacific element. 1 species (8%).

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Improving visualization in shoulder arthroscopy

  • Emily R. McDermott;David J. Tennent;Daniel J. Song
    • Clinics in Shoulder and Elbow
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    • v.26 no.4
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    • pp.455-461
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    • 2023
  • Arthroscopic shoulder procedures are one of the most common procedures used to restore function through minimally invasive techniques. With the demand for shoulder arthroscopic procedures comes the need for safe, effective, and efficient surgery that maximizes patient outcomes while minimizing complications. Many variables contribute to visualization in shoulder arthroscopy including vascular anatomy, blood pressure control, arthroscopic pump systems, turbulence control, epinephrine, and tranexamic acid. Furthermore, patient positioning can have a dramatic effect on visualization with both the beach chair position and lateral decubitus positioning having various strengths and weaknesses depending on the intended procedure being performed. The purpose of this review is to examine the benefits and complications reported in the literature for improving visualization in shoulder arthroscopy.