• Journal of mucopolysaccharidosis and rare diseases
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• v.1 no.2
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• pp.35-39
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• 2015

Sleep problems occur frequently among patients with Prader-Willi syndrome (PWS). The most common problem is excessive daytime sleepiness (EDS) that are closely related to of sleep-related breathing disorder (SRBD) such as obstructive sleep apnea (OSA) and congenital hypoventilation syndrome. Obesity, craniofacial dysmorphism and muscular hypotonia of patients with PWS may increase the risk of SRBD. Sleep apneas can interrupt the continuity of sleep, and these disruptions result in a decrease in both the quality and quantity of sleep. In addition to SRBD, other sleep disorders have been reported, such as hypersomnia, a primary abnormality of the rapid eye movement (REM) sleep and narcolepsy traits at sleep onset REM sleep. Patients with PWS have intrinsic abnormalities of sleep-wake cycles due to hypothalamic dysfunction. The treatment of EDS and other sleep disorders in PWS are similar to standard treatments. Correction of sleep hygiene such as sufficient amount of sleep, maintenance of regular sleep-wake rhythm, and planned naps are important. After comprehensive evaluation of sleep disturbances, CPAP or surgery should be recommended for treatment of SRBD. Remaining EDS or narcolepsy-like syndrome are controlled by stimulant medication. Bright light therapy might be beneficial for disturbed circadian sleep-wake rhythm caused by hypothalamic dysfunction.

• Journal of the East Asian Society of Dietary Life
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• v.22 no.1
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• pp.68-74
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• 2012

This study was performed to process Tofu as an hypolipidemic food using black ginseng. Before processing we performed the ameliorating effect of black ginseng on the serum levels of triglyceride and total cholesterol in diabetic mice (db/db mice). As a result, the diabetic mice, whose diet was supplemented with black ginseng has a reduced level of serum lipid total cholesterol ($124.58{\pm}10.59mg/dL$) compared to non-supplemented diabetic mice, The supplemented mice exhibited a significant decrease (p<0.05) in serum lipid triglycerides ($80.32{\pm}35.40mg/dL$), which provided the efficacy of black ginseng in reducing hyperlipemia, thus indirectly proving the prevention and treatment of obesity. Then we processed Tofu as a hypolipidemic food using 0~8% black ginseng extract. We evaluated the quality characteristic after producing black ginseng Tofu. For color value, as the addition level of color increases, the value of L (lightness) decreased and a (redness), b (yellowness) increased. With increase in black ginseng concentrate additional level increases, the hardness, gumminess, and chewiness values increased (p<0.05), but the springiness and cohesiveness showed no significant differences. In case of sensory evaluation, Tofu with the addition of 2% black ginseng concentrate (BGT2) showed the highest preference overall. To sum up, black ginseng demonstrated pharmacological effects in treating diabetic complications like hyperlipidemia and reducing body deposit fat.

• Preventive Nutrition and Food Science
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• v.7 no.1
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• pp.62-66
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• 2002

As inhibitors of carbohydrate-digesting enzymes can prevent hyperglycemia that is known to cause many macrovascular complications, they may prove a useful adjunct to hypocaloric diets in patients with type 2 diabetes and obesity. Inhibitory activities of two hundred and fifteen kinds of medicinal herb extracts against $\alpha$-glucosidase (EC 3.2.1.20) and $\alpha$-amylase (EC 3.2.1.1) have been investigated in vitro. Adenophora triphylla, Aneilema keisak, and Morus bombysis significantly suppressed rat intestinal $\alpha$-glucosidase activity iu vitro. Porcine pancreatic amylase was efficiently inhibited by methanol extracts of Epimedium koreanum, Campsis grandiflora and Salvia plebeia. Methanol extract of Epimedium koreanum among the medicinal herbs tested showed the strongest inhibitory activity against porcine pancreatic $\alpha$-amylase with 0.1 mg/ML of $IC_{50}$/. The herb extract also improved glucose tolerance in ICR mice when loaded with 0.9 g soluble starch per kg body weight. Taken together, Epimedium koreanum merits further evaluation as a therapeutic measure.

• Korean Journal of Pharmacognosy
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• v.45 no.1
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• pp.88-92
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• 2014

Lysimachia foenum-graecum (LF) has been used for home remedy of common cold and headache in China. Foenumoside B from LF has been reported for anti-obesity effects. We used foenumoside B as a marker for content evaluation of different parts of LF. Ethanol extract of LF was used for isolation of foenumoside B and purified further by column chromatography. The structure was identified as foenumoside B by interpretation of spectroscopic analysis, including $^1H$-, $^{13}C$-NMR and FT-ICR-MS. High-performance liquid chromatography (HPLC) method was used to compare the quantitative level of foenumoside B in different parts of LF. Foenumoside B contents in the leaf, stem, and aerial part showed significant differences. Contents of foenumoside B was detected highly in the leaf extracts. The results would be useful for efficient extraction of foenumoside B in LF.

• Fashion & Textile Research Journal
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• v.21 no.6
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• pp.830-836
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• 2019

A diverse range of products are currently being sold; however, it is very difficult to purchase All-in-One patterns that reflect the body types of the elderly stage in the open market. This study is to develop specialized All-in-One patterns by assessing obese body types characteristics of the elderly social class. Five healthy women with typical obese body types in the elderly stage with busts, waists, and hips surpassing 100 cm were chose as test subjects. The three subjects for the wearing experiment are those with more than one year of experience wearing a bodysuit. A self-evaluation was made three times by looking in the mirror. The data from this study was processed to find averages and deviations; in addition, and a t-test was performed using the SPSS 24 statistical software. A total of 13 body parts were measured prior to and while wearing the specialized All-in-One patterns. Significant results were obtained from all 12 items. All-in-One for research appears to have produced a high level of satisfaction for subjects. This study can provide basic data on elevating the levels of satisfaction of the consumers in their elderly stages with special body types that deviate from standard body types at the time of wearing garments as well as for inner-wear companies to graft this market as a high-value-added niche market.

• Biomolecules & Therapeutics
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• v.25 no.2
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• pp.165-170
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• 2017

Cordyceps bassiana is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. This mushroom has recently demonstrated to have an ability to reduce 2,4-dinitrofluorobenzene-induced atopic dermatitis symptoms in NC/Nga mice. In this study, we further examined phytochemical properties of this mushroom by column chromatography and HPLC analysis. By chromatographic separation and spectroscopic analysis, 8 compounds, such as 1,9-dimethylguanine (1), adenosine (2), uridine (3), nicotinamide (4), 3-methyluracil (5), 1,7-dimethylxanthine (6), nudifloric acid (7), and mannitol (8) were identified from 6 different fractions and 4 more subfractions. Through evaluation of their anti-inflammatory activities using reporter gene assay and mRNA analysis, compound 1 was found to block luciferase activity induced by $NF-{\kappa}B$ and AP-1, suppress the mRNA levels of cyclooxygenase (COX)-2 and tumor necrosis factor $(TNF)-{\alpha}$. Therefore, our data strongly suggests that compound 1 acts as one of major principles in Cordyceps bassiana with anti-inflammatory and anti-atopic dermatitis activities.

• The Korean Journal of Food And Nutrition
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• v.27 no.5
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• pp.921-928
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• 2014

This study investigated the quality characteristics of cookies containing capsaicin, the main source of spicy taste in pepper, which is well known for its various functions such as anti-oxidant, anti-cancer, anti-inflammatory, and anti-obesity activities, as well as pain-relief effect. Cookie samples were made by adding the capsaicin powder at different levels, including 40 mg% (C1), 85 mg% (C2), and 150 mg% (C3). In this study, measurement of the moisture, pH, color, spread factor, hardness, anti-oxidant activity, and sensory evaluation of the cookies was carried out. The results showed that the anti-oxidant activity increased when more capsaicin powder was added to the cookies (p<0.001). The moisture also increased with increasing capsaicin powder content (p<0.05), while the pH did not show any significant changes. As for the colors, the L value and b value decreased as more capsaicin powder was added, while the a value increased. The spread factor also increased significantly with the increase of capsaicin powder (p<0.01). Although the hardness increased with capsaicin powder content, no statistically significant differences were observed among the various cookies. In the sensory evaluation, Cookies containing 40 mg of capsaicin obtained the highest score in color, while cookies containing 150 mg of capsaicin showed the highest score in taste, texture, and overall acceptability.

• Journal of The Korean Society of Integrative Medicine
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• v.1 no.4
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• pp.67-74
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• 2013

Purpose : The purpose of this study was to investigate the effect of horseback riding exercise for BMI(body mass index) and waist circumference in the obese women. Method : 20 subjects in Y-equestrian were randomly divided two group, horseback machine exercise(HME) group and horseback-riding exercise(HRE) group. Each group carried out 30 minutes exercise two times a week for 8 weeks. BMI were measured for body composition, and evaluation of waist circumference. Result : The results were as follows, the BMI(body mass index) between horseback machine exercise and horseback-riding exercise groups in post-test, were significantly different in measures(p<.05). And there were significant in two group after exercise(p<.05). The waist circumference between horseback machine exercise and horseback-riding exercise groups in post-test, were significantly different in measures(p<.05). And there were significant in two group after exercise(p<.05). Conclusion : These finding revealed that horseback-riding exercise was effective on BMI and waist circumrerence of obese women so that these exercise can be new altematives exercise for obesity management in the obese women.

• Korean Journal of Community Nutrition
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• v.4 no.4
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• pp.539-545
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• 1999

This study was intended to develop food and nutrition cyberclass contents for nonmajor students at university. We investigated universities which offered food and nutrition related courses in 1998 by a telephone survey in order to select the most appropriate lecture contents for the nonmajor university students. We investigated to select the most needed lecture contents for the students, 15 questions on evaluation of cyberclasses which they took. The number of subjects were 140 students of ‘C’university who registered for nonmajor food and nutrition course in 1998. Among 140 students, 80 were cyberclass students and 60 were non cyberclass students. The results of the survey were as following : Fifty-five universities out of 62 had curriculums on food and nutrition in 1998 and 36,802 students attended the non major food and nutrition lectures. 84.9% of the respondents had their own computes and the main application mostly used was word processing. Additionally, 33.3% of them used on-line communications and 81.4% of them used internet. The most interesting subject of the respondents was ‘disease and nutrition management’. The male respondents were concerned more about ‘alcohol and health’, whereas the females were concerned about ‘obesity and weight control’.

• The Korean Journal of Food And Nutrition
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• v.17 no.4
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• pp.356-367
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• 2004

This study was performed to evaluate the effectiveness of a nutritional education program conducted by public health center in Jinju city for obese women. The subjects of this study consisted of 27 obese women(BMI $\geq$ 25) aged 35∼55 years in Jinju area, and the educational period was 6 weeks. We evaluated the anthropometric parameters and biochemical indices, dietary habits, dietary behaviors, nutritional attitude of obese women before and after the nutritional education. And also daily intake during the educational period were measured. Weight, obesity index, BMT, waist circumferences and hip circumferences of obese women were significantly decreased(p<0.001) after nutritional education, but changes of WHR, systolic blood pressure and diastolic blood pressure were not significant. There were no significant difference in total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, LDH and blood glucose level in serum before and after the nutritional education, but the indices tend to decrease after the nutritional education. There was significantly different change of dietary behaviors in 3 items among the dietary behavior after the nutritional education. Their dietary habit, dietary behavior and nutritional attitude scores were significantly improved after the nutritional education. Mean daily energy intakes was low compared with the RDA as 78.88%. The average carbohydrates, protein, fat ratio on the energy intakes was 63 : 17 : 20. The proportion of energy intake from snacks the was 12.91${\pm}$6.15%.