• Journal of Nutrition and Health
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• 제34권2호
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• pp.198-212
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• 2001

This study was designed to compare the prevalence rate of obesity, food attitude, food frequency and food habits between children in Kangnung and Seoul areas. 1,005 children aged 9-12 were included in this study. They were composed of 343 children living in Kangnung from one elementary school, and 662 children in Seoul from two elementary schools. The body weight, height, waist and hip circumferences of children were measured and food frequency scores of Korean and Western foods were examined by questionnaire. And questionnaires about food attitude, food habits and life style were administered to the mother of each child. There was no significant difference in body weight and obesity index among three groups(one school of Kangnung area and two schools of Seoul area). The male children\`s prevalence rates of obesity in Kangnung and two schools(A, B) of Seoul were 10.3%, 10.3% and 7.3%, respectively. Female children\`s prevalence rate were 5.4%, 4.7%, and 6.3%, respectively. Children in Seoul turned out to more frequently eat such Korean foods like pulkogi, kalbi and fried rice and such western foods like butter, margarine, hamburger, pizza, and fried chicken. Children in Seoul had more tendency to eat regularly and spent less time in sleeping and watching TV and more time in exercise than the respondents in Kangnung. The obesity index of parents had a significantly positive correlation with that of children. These results suggest that children in Seoul have tendency to eat high-energy food frequently and to have more energy expenditure than children in Kangnung. In conclusion, further studies on the evaluation of energy intake and energy expenditure of obese and normal children different in area should be conducted. (Korean J Nutrition 34(1) : 198∼212, 2001)

• 대한한방소아과학회지
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• 제32권3호
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• pp.26-43
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• 2018

Objectives The purpose of this study was to analyze recent traditional Chinese medicine clinical studies for treatment of childhood obesity. Methods We analyzed 11 clinical studies from January, 2000 to March, 2018 about childhood obesity from the China Academic Journal (CAJ) and China National Knowledge Infrastructure (CNKI). All selected studies were Randomized Controlled Trials and analyzed in order of publication year, demographic information, treatment method, evaluation methods, results, adverse reactions and relapse after treatment discontinuation. Results The main Traditional Chinese Medicine (TCM) treatment was the herbal decoctions, granules and pills. In most studies, the total efficacy of the treatment group was reported to be higher than that of the control group. Adverse reactions were found in small number of studies. Frequently used medical herbs were Crataegi Fructus (山?), Atractylodis Rhizoma (蒼朮), Citri Pericarpium (陳皮), Poria (茯?), and Nelumbinis Folium (荷葉). Also, Water-draining and swelling-dispersing medicinal (利水退腫藥), Qi-regulating medicinal (理氣藥), Resolving dampness with aroma medicinal (芳香化濕藥), Blood-activating and stasis-dispelling medicinal (活血祛瘀藥), Qi-tonifying medicinal (補氣藥), and Digestant medicinal (消食藥) were commonly used. Conclusions This study showed that traditional Chinese medicine, especially herbal medicine treatment can be effective and safe option for treating childhood obesity. These research results can be utilized in other clinical studies as well as in treatment of childhood obesity. Additional well-designed randomized controlled trials and systematic reviews are need to confirm the conclusion.

• 한국산학기술학회논문지
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• 제12권2호
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• pp.746-752
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• 2011

본 연구는 BMI와 체지방율을 이용하여 비만도를 평가하고, 관상동맥질환위험인자들과 비만도와의 관련성을 검토하고자 2008년 1월부터 2009년 12월까지 2년 동안에 한 대학병원 건강검진센타에 내원하여 종합건강검진을 받았던 30세 이상의 일반 시민 3,731명(남자 2,312명, 여자 1,419명)을 분석대상으로 하였다. 연구결과 BMI와 체지방율을 대비하여 평가한 비만도는 "정상군"30.2%, "외관형 비만군"8.9%, "체지방형 비만군"31.2%, "비만군"29.8%이었다. 남성은 여성에 비해 "정상군"과 "외관형 비만군"의 비율이 높은 반면, 여성은 남성에 비해 "체지방형 비만군"과 "비만군"의 비율이 유의하게 높았으며, 연령별로는 40대와 50대 연령군에서 "비만군"의 비율이 유의하게 높았다. CRF치의 변화에서 SBP, DBP, TC, HDL-C, LDL-C 및 TG는 "정상군"보다 "외관형 비만군"과 "비만군"에서 유의하게 높았고, SBP, TC 및 LDL-C는 "정상군"보다 "체지방형 비만군"과 "비만군"에서 유의하게 높았다. 비만도에 따른 CRF 증가의 위험비는 "정상군"에 비해 "비만군"에서 가장 높았으며, 다음은 "외관형 비만군", "체지방형 비만군"의 순으로 위험비가 높아졌다.

• Journal of Nutrition and Health
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• 제47권6호
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• pp.403-415
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• 2014

본 연구는 국민건강영양조사 데이터를 활용하여 우리나라 성인에서 성별 허리둘레를 기준으로 한 복부비만 여부에 따른 혈액지표, 생활습관, 식사섭취 상태 및 식사의 질을 분석한 결과, 남성과 여성 모두에서 허리둘레 기준 복부비만군의 경우 정상군에 비해 대사적 지표 (혈중 콜레스테롤, 중성지방, 혈당 및 혈압)가 모두 유의적으로 높게 나타났으며, 여성 허리둘레 기준 복부비만군에서 비타민 $B_2$, 칼슘, 인 및 칼륨 등 미량영양소 섭취의 질이 정상군에 비해 유의적으로 낮았고, 식품 섭취의 다양성을 의미하는 식품군 점수 및 총 식품점수도 비만군이 정상군에 비해 유의적으로 낮게 나타났다. 또한 여성의 경우 식품 섭취의 다양성 (총 식품점수)이 증가할수록 허리둘레 기준 복부비만 위험도가 유의적으로 낮게 나타난 의미 있는 결과를 도출하였다. 이와 같은 결과는 비만의 관리 및 예방을 위해 영양소의 과부족이 없고 미량영양소의 적절한 공급을 가능하게 하는 다양한 식품의 섭취를 권장할 수 있는 근거자료 및 영양교육의 기초자료로 활용할 수 있을 것으로 사료된다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제23권4호
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• pp.179-192
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• 2023

Obstructive sleep apnea (OSA) is a common sleep-breathing disorder associated with significant comorbidities and perioperative complications. This narrative review is aimed at comprehensively overviewing preoperative risk evaluation and perioperative management strategies for patients with OSA. OSA is characterized by recurrent episodes of upper airway obstruction during sleep leading to hypoxemia and arousal. Anatomical features, such as upper airway narrowing and obesity, contribute to the development of OSA. OSA can be diagnosed based on polysomnography findings, and positive airway pressure therapy is the mainstay of treatment. However, alternative therapies, such as oral appliances or upper airway surgery, can be considered for patients with intolerance. Patients with OSA face perioperative challenges due to difficult airway management, comorbidities, and effects of sedatives and analgesics. Anatomical changes, reduced upper airway muscle tone, and obesity increase the risks of airway obstruction, and difficulties in intubation and mask ventilation. OSA-related comorbidities, such as cardiovascular and respiratory disorders, further increase perioperative risks. Sedatives and opioids can exacerbate respiratory depression and compromise airway patency. Therefore, careful consideration of alternative pain management options is necessary. Although the association between OSA and postoperative mortality remains controversial, concerns exist regarding adverse outcomes in patients with OSA. Understanding the pathophysiology of OSA, implementing appropriate preoperative evaluations, and tailoring perioperative management strategies are vital to ensure patient safety and optimize surgical outcomes.

• 한방비만학회지
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• 제19권1호
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• pp.12-23
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• 2019

Objectives: Obesity is associated with a high mortality risk and impairment in health-related quality of life (HRQOL). The aim of this article is to examine the impact of weight loss on HRQOL and which questionnaires sensitively reflect weight loss effects on HRQOL. Methods: PubMed, Scopus, Research Information Sharing Service, and Korean Studies Information Service System were searched for the studies related to weight loss and HRQOL, published from 2009 to 2018. A total of 28 studies were eligible for inclusion. HRQOL results after weight loss from selected studies were classified and reported according to questionnaires. Results: Twenty-two studies reported statistically significant HRQOL improvements after weight loss and especially, all of studies with weight loss of more than 5% reported HRQOL improvements. HRQOL questionnaires were classified as generic, obesity-related and depression questionnaires. The most commonly used questionnaires were Short-Form health survey 36 (SF-36), Impact of Weight on Quality Life-Lite (IWQOL-Lite) and Beck Depression Inventory (BDI) respectively. SF-36 had a tendency to reflect physical health. IWQOL-Lite score was tended to be changed sensitively according to weight change. Depression questionnaires including BDI reported improvement of depression while mental aspects of SF-36 not changed in same studies. Conclusions: Improvements of HRQOL were noted in studies with weight loss of more than 5%. The main questionnaires for evaluating HRQOL were SF-36, IWQOL-Lite and BDI. It is suggested to use these questionnaires together for evaluating multiple aspects of impact of weight loss on HRQOL.

• 한국보건간호학회지
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• 제18권2호
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• pp.299-311
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• 2004

Purpose: Somatotype drawing developed by Sorensen et al.(1983) has been evaluated as a simple instrument of obesity level without real somatic measuring as height and weight. This study was designed to validate somatotype drawings for obesity assessment by bioelectrical impedance body component analysis. Method: At first questionnaire of somatotype drawing was done. Subjects were measured body component by bioelectrical impedance analysis as weight, BMI(body mass index), WHR(waist-hip ratio), body water, protein mass, mineral mass, body fat mass, skeletal muscle mass, soft lean mass, fat free mass and percent body fat. We evaluated correlations between these data and somatotype drawings and tried to grouping of somatotype drawings with the means of major body component value. Result: The data were collected from 205 college women whose height and weight were $161.2\pm4.8,\;55\pm8.3$. Spearman's correlation coefficients of somatotype drawing were 0.74 with BMI, 0.68 with weight 0.69 with body fat mass, 0.65 with WHR. 0.64 with percent body fat after adiusted age. The grade of somatotype drawings were grouped as 1-2, 3-4, 5-6. 7-9 by BMI, body fat mass, weight, 1, 2-4, 5-6, 7-9 by WHR and 1-2, 3-4, 5-9 by percent body fat(ANOVA and Duncan's method). Conclusion: So quick instrument using somatotype drawings were useful tools for evaluation of obesity level and is applicable to screen degree of body fat in self-administered questionnaire survey.

• Korean Chemical Engineering Research
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• 제54권2호
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• pp.223-228
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• 2016

본 논문은 PDMS을 기반으로 한 미세접촉인쇄법을 사용하여 보다 효율적으로 지방세포를 선택적으로 배양접시에 부착시켰으며 패터닝 된 배양접시에서 지방세포가 빠르게 지방분화를 가능하게 하였다. PDMS을 이용한 선택적 표면 처리 방법은 기존의 세포칩 제작과 달리 소량의 유기용매사용, 저가의 장비 사용, 또한 효율적으로 특정 지역 안에서 지방세포를 고정화하고 성장시킬 수 있으며 이를 통해 지방세포의 생리학적 상태를 손쉽게 관찰할 수 있는 분석 기술로 활용된다. 이렇게 구성된 지방세포칩 위에 대표적인 비만 억제제 약물인 Orlistat을 $0.2{\mu}M{\sim}5.0{\mu}M$ 농도로 처리하였을 때 대조군에 비하여 최대 26.5%의 억제 효과가 나타남을 확인하였다. 따라서, 본 논문에서 제안하는 방법을 통하여 다양한 비만 억제제 약물 탐색을 위한 세포칩으로 활용이 가능할 것으로 기대된다.

• 디지털융복합연구
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• 제13권9호
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• pp.479-487
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• 2015

본 연구는 20대 여성의 외모만족도, 외모지향성, 외모평가 및 자아존중감을 파악하고 각 요인들이 비만스트레스에 미치는 영향을 알아보고자 시행되었다. 분석결과 20대 여성은 실제 BMI(Body Mass Index)보다 주관적 체형을 더 크게 인식하고 있었다. 대상자의 제 변수간의 상관관계를 살펴본 결과, 외모지향성(r=.386, p=<.001), 자아존중감(r=.324, p=<.001)으로 정적상관성을, 외모평가(r=-453, p=<.001), 외모만족도(r=-.560, p=<.001)는 부적상관성을 보였다. 위계적 회귀방법으로 비만스트레스에 영향을 미치는 요인을 분석한 결과, 1단계 모형에서 외모만족도 31.3%, 2단계 모형에서 외모지향성, 외모평가, 외모만족도가 45.3%, 3단계 모형에서 주관적 체형, BMI 및 제 변수가 54.7%를 설명하였다. 분석결과를 토대로 20대 여성에게 실제 정상BMI를 가진 체형이 가장 이상적인 체형임을 인식하는 교육과 삶의 지표를 외형보다 내면에 둘 수 있도록 다양한 프로그램을 마련하는 것이 20대 여성의 비만스트레스를 다소나마 줄여 줄 수 있을 것으로 사료된다.

• 한국식품위생안전성학회지
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• 제25권1호
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• pp.30-35
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• 2010

식품 중 비만치료제 시부트라민의 유사물질인 데스메틸시부트라민을 규명하였다. 데스메틸시부트라민 함유 시료로부터 메탄올을 이용하여 대상성분을 추출하고 핵산으로 세척 등을 통하여 정제한 후 HPLC/PDA, HPLC/MS, HPLC/MSIMS 및 NMR로 확인 및 분석하였다. 또한, 식품 중 시부트라민 및 데스메틸시부라민을 분석하기 위하여 균질화한 시료를 디클로로메탄으로 추출하여 여과, 농축하고 메탄올로 희석하여 HPLC/UV로 분석하였다. 평균 회수 87~91%이었으며, 정량한계는 $2.5\;{\mu}g/kg$이었다. 분석 결과 식품시료 54건에서 시부트라민 및 데스메틸시부트라민이 검출되지는 않았다.