• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10739-10743
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• 2015

The present study aimed at evaluating and comparing the diagnostic performance of B-mode ultrasound (US), elastography score (ES), and strain ratio (SR) for the differentiation of breast lesions. This retrospective study enrolled 431 lesions from 417 in-hospital patients. All patients were examined with both conventional ultrasound and elastography. Two experienced radiologists reviewed ultrasound and elasticity images. The histopathologic result obtained from ultrasound-guided core biopsy or operation excisions were used as the reference standard. Pathologic examination revealed 276 malignant lesions (64%) and 155 benign lesions (36%). A cut-off point of 4.15 (area under the curve, 0.891) allowed significant differentiation of malignant and benign lesions. ROC (receiver-operating characteristic) curves showed a higher value for combination of B-mode ultrasound and elastography for the diagnosis of breast lesions. Conventional ultrasound combined elastography showed high sensitivity, specificity, and accuracy for group II lesions (10mm${\leq}20mm$). Elastography combined with conventional ultrasound show high specificity and accuracy for differentiation of benign and malignant breast lesions. Elastography is particularly important for the diagnosis of BI-RADS 4 and small breast lesions.

• 정보교육학회논문지
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• 제15권2호
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• pp.307-317
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• 2011

영재교육에 있어서 가장 중요한 문제 중의 하나는 영재성에 대한 정의와 영재를 정확하게 판별하는 것이다. 영재의 판별은 영재성의 정의에 근거해야 하는데, 영재성의 정의는 사회의 가치관에 따라 다르며, 영재성은 개념적인 용어이므로 직접적으로 측정하기 어렵기 때문에 영재를 판별하는 것도 명확한 기준에 따른 객관적이고 절대적인 도구는 존재하지 않는다. 최근 영재교육이 상위학교 진학에 도움이 된다고 하여 많은 학부모들이 영재교육을 특목고와 명문대 진학을 위한 발판이나 수단으로 생각하고 있다. 본 연구는 미래사회가 요구하는 영재를 판별할 방안을 개발하기 위하여 영재선발에 대한 기초적인 이해를 바탕으로, 현행 영재 선발 방법의 문제점을 분석하고 시사점을 도출한 다음, 이를 활용한 판별 전략과 선발 절차 및 방법 등을 제안하고 있다. 본 논문에서는 미래사회에 성공할 가능성이 많은 영재를 선발하기 위해서는 인지적인 요소 외에 정의적인 요소에 대한 평가가 이루어져야 하며, 영재성을 가진 모든 영재들에게 영재교육의 기회를 확대하고, 영재 프로그램 배치 후에도 영재성에 대한 평가가 지속적으로 이루어져야 함을 밝히고 있다.

• 한국산학기술학회논문지
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• 제14권6호
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• pp.2767-2772
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• 2013

균형은 일상생활의 기본적인 요소이며 균형능력의 평가는 무게중심의 측정으로 한다. 본 연구에서는 뇌졸중 환자를 대상으로 균형 능력을 평가하기 위한 Balancia 프로그램의 신뢰도와 타당도를 측정하고자 하였다. COP의 측정을 위한 장비로는 Wii Balance Board를 이용하였다. 연구는 39명의 뇌졸중 환자들 대상으로 하였다. 신뢰도 검사는 동요거리, 동요속도, area95% 결과값의 검사자간 신뢰도와 검사자내 신뢰도를 실시하였다. 검사자내 신뢰도는 검사-재검사의 방법으로 급간내 상관계수를 측정하여 ICC .793-.939로 높은 신뢰도를 보였고, 검사자간 신뢰도에서도 ICC .791-.955로 높은 신뢰도를 보였다. 타당도는 Accusway와 비교하여 ICC .851-.955로 매우 높은 일치도를 보였다. 따라서 본 연구를 통해 Balancia 프로그램이 뇌졸중 환자의 균형 능력을 평가하는데 높은 신뢰도와 타당도를 가진 프로그램으로 입증되었다.

• International Journal of Fluid Machinery and Systems
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• 제2권4호
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• pp.353-362
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• 2009

In the process of turbine modernizations, the investigation of the influences of water passage roughness on radial flow machine performance is crucial and validates the efficiency step up between reduced scale model and prototype. This study presents the specific losses per component of a Francis turbine, which are estimated by CFD simulation. Simulations are performed for different water passage surface roughness heights, which represents the equivalent sand grain roughness height. As a result, the boundary layer logarithmic velocity profile still exists for rough walls, but moves closer to the wall. Consequently, the wall friction depends not only on roughness height but also on its shape and distribution. The specific losses are determined by CFD numerical simulations for each component of the prototype, taking into account its own specific sand grain roughness height. The model efficiency step up between reduced scale model and prototype value is finally computed by the assessment of specific losses on prototype and by evaluating specific losses for a reduced scale model with smooth walls. Furthermore, surveys of rough walls of each component were performed during the geometry recovery on the prototype and comparisons are made with experimental data from the EPFL Laboratory for Hydraulic Machines reduced scale model measurements. This study underlines that if rough walls are considered, the CFD approach estimates well the local friction loss coefficient. It is clear that by considering sand grain roughness heights in CFD simulations, its forms a significant part of the global performance estimation. The availability of the efficiency field measurements provides an unique opportunity to assess the CFD method in view of a systematic approach for turbine modernization step up evaluation. Moreover, this paper states that CFD is a very promising tool for future evaluation of turbine performance transposition from the scale model to the prototype.

• 대한의용생체공학회:의공학회지
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• 제29권5호
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• pp.400-407
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• 2008

A health index was proposed that evaluates personal health state from both measured physiological variables and survey questions. Four health indices were defined such as cardiovascular index, stress index, obesity index, and management index. The total health index was calculated by summing these four health indices. Physiological variables such as blood pressure, heart rate variability(HRV), accelerated photoplethysmograph(APG), and body fat percentage were non-invasively measured and a survey questionnaire that asks personal health state, exercise intensity, and food preference was developed. The suggested health index was applied to thirty eight persons including 30 patients and 8 normal persons with an average age of 51.8. The average health index was estimated to be 75.1 out of 100 points. Young age group(below 50) and men group showed higher health indices than the aged(over 50) and women groups. The correlation coefficient between the cardiovascular index and stress index was found to be 0.513, which means stress is related to cardiovascular health state. The correlation coefficient between the measurements and survey questions was 0.385 for the cardiovascular index. It was as low as 0.182 for the stress index. More case studies may improve correlations between measurements and survey questions, and then, the current health index system may develop as an effective tool to evaluate personal health state.

• 대한후두음성언어의학회지
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• 제28권2호
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• pp.84-88
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• 2017

Background and Objectives : The purpose of this study was to compare the usefulness of Cepstral peak prominence (CPP) with parameter of Multiple Dimensional Voice Program (MDVP) in evaluating unilateral vocal fold paraylsis patients with subjective voice impairment. Materials and Methods : From July 2014 to August 2016, 37 patients with unilateral vocal fold paralysis who had been diagnosed with unilateral vocal fold paralysis and had received two or more voice tests before and after the diagnosis were evaluated for maximum phonation time (MPT), MDVP and CPP. Respectively. Voice tests were performed with short vowel /a/ and paragraph reading. Results : The CPP-a (CPP with vowel /a/) and CPP-s (CPP with paragraph reading) of the Cepstrum were statistically negatively correlated with G, R, B, and A before the voice therapy. Jitter, Shimmer, and NHR of MDVP were positively correlated with G, R, B. Jitter, Shimmer, and NHR of the MDVP were significantly correlated with the Cepstrum index. G, B, A and CPP-a and CPP-s showed a statistically significant negative correlation and a somewhat higher correlation coefficient between 0.5 and 0.78. On the other hand, in MDVP index, there was a positive correlation with G and B only with Jitter of 0.4. Conclusion : CPP can be an important evaluation tool in the evaluation of speech in the unilateral vocal cord paralysis when speech energy changes or the cycle is not constant during speech.

• Mass Spectrometry Letters
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• 제5권4호
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• pp.110-114
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• 2014

The method of direct mass spectrometry profiling is reliable and reproducible for the rapid identification of clinical isolates of bacteria and fungi. This is the first study evaluating the approach of MALDI-TOF mass spectrometry profiling for rapid identification of carbapenemase-resistant enterobacteriaceae (CRE). Proof of concept was achieved by the discrimination of CRE using MALDI Biotyper MS based on the protein. This profiling appears promising by the visual observation of consistent unique peaks, albeit low intensity, that could be picked up from the mean spectra (MSP) method. The Biotyper MSP creation and identification methods needed to be optimized to provide significantly improved differences in scores to allow for subspecies identification with and without carbapenemases. These spectra were subjected to visual peak picking and in all cases; there were pertinent differences in the presence or absence of potential biomarker peaks to differentiate isolates. We also evaluated this method for potential discrimination between different carbapenemases bacteria, utilizing the same strategy. Based on our data and pending further investigation in other CREs, MALDI-TOF MS has potential as a diagnostic tool for the rapid identification of even closely related carbapenemases but would require a paradigm shift in which Biotyper suppliers enable more flexible software control of mass spectral profiling methods.

• Archives of Plastic Surgery
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• 제39권3호
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• pp.227-231
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• 2012

Background : The ankle brachial pressure index (ABI) is a simple, useful method for diagnosing peripheral artery disease (PAD). Although the ABI is an objective diagnostic method, it has limited reliability in certain scenarios. The aim of the present study was to determine the accuracy and reliability of the toe brachial index (TBI) as a diagnostic tool for detecting stenosis in PAD, associated with normal or low ABI values. Methods : ABI and TBI values were measured in 15 patients with diabetic gangrene who were suspected of having lower extremity arterial insufficiency. The ABI and TBI values were measured using a device that allowed the simultaneous measurement of systolic blood pressure in the upper and lower extremities. In addition, the ABI and TBI values were compared pre- and post-angiography. Results : Patients with an ABI of 0.9-1.3 showed almost no difference between the 2 measurements. The patients with TBI >0.6 had no arterial insufficiency. The patients with TBI <0.6 required vascular intervention with ballooning. After the angiography, the gangrenous wounds decreased in size more rapidly than they did prior to the intervention. Conclusions : Our findings suggest that TBI is the method of choice for evaluating lower limb perfusion disorders. This result requires further studies of TBI in a larger number of patients. Future long-term studies should therefore evaluate the utility of TBI as a means of screening for PAD and the present findings should be regarded as preliminary outcomes.

• 한국도로학회논문집
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• 제14권1호
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• pp.73-83
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• 2012

본 연구에서는 하이패스 차로의 속도감소를 유도하기 위한 적절한 노면표시를 도출하기 위하여 감성공학적 분석방법을 활용하여 연구를 수행하였다. 현재 고속도로 영업소에서는 감속유도를 위하여 하이패스 차로에 갈매기 노면표시를 설치하여 운영하고 있다. 본 연구에서는 하이패스 차로의 감속유도를 위하여 갈매기 노면표시 및 Peripheral Transverse Bar(PT bar)에 대한 효과평가를 실시하고, 두 가지 노면표시를 조합하여 6가지 시나리오를 도출하였다. 도출된 시나리오에 대하여 이용자의 Perception 측정 및 분석을 통한 노면표시 설계 시 Human Factor를 반영할 수 있는 방법론을 제시하였다. 분석결과 빗살무늬의 PT bar 및 $60^{\circ}$ 각도의 갈매기 노면표시의 조합시나리오가 가장 적절한 노면표시로 선정되었다. 본 연구의 결과는 하이패스 차량들의 통과속도를 감소시켜 고속도로의 안전성을 높일 수 있을 것으로 기대된다.

• 대한핵의학회지
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• 제28권1호
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• pp.31-36
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• 1994

$^{201}Tl-^{99m}Tc$ 감영스캔이 시행되었던 65명의 환자에서 $^{201}Tl-^{99m}Tc$ 감영스캔의 진단적 가치와 위 음성과 위 양성의 원인에 대해 조사하였다. 이들 중 21예가 부갑상선선종으로 확진되었고, 이들에서 $^{201}Tl-^{99m}Tc$ 감영스캔의 예민도는 90.5%, 특이도는 97.6%였다. 위 음성을 보인 예는 낭종성 괴사를 보인 부갑상선선종과 크기가 $1.5{\times}1{\times}0.8 cm$ 정도로 작은 종양이었다. 위 양성을 보인 1예는 무 기능성 갑상선종이었다. 결론적으로 $^{201}Tl-^{99m}Tc$ 감영스캔은 부갑상선 종괴를 찾아내는데 특이도와 예민도가 높은 검사로 생각된다.