• Genomics & Informatics
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• 제11권4호
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• pp.211-217
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• 2013

Many biobanks were established as biorepositories for biomedical research, and a number of biobanks were founded in the 1990s. The main aim of the biobank is to store and to maintain biomaterials for studying chronic disease, identifying risk factors of specific diseases, and applying personalized drug therapies. This report provides a review of biobanks, including Korean biobanks and an analysis of sample volumes, regulations, policies, and ethical issues of the biobank. Until now, the top 6 countries according to the number of large-scale biobanks are the United Kingdom, United States, Sweden, France, the Netherlands, and Italy, and there is one major National Biobank of Korea (NBK) and 17 regional biobanks in Korea. Many countries have regulations and guidelines for the biobanks, and the importance of good management of biobanks is increasing. Meanwhile, according to a first survey of 456 biobank managers in the United States, biobankers are concerned with the underuse of the samples in their repositories, which need to be advertised for researchers. Korea Biobank Network (KBN) project phase II (2013-2015) was also planned for the promotion to use biospecimens in the KBN. The KBN is continuously introducing for researchers to use biospecimens in the biobank. An accreditation process can also be introduced for biobanks to harmonize collections and encourage use of biospecimens in the biobanks. KBN is preparing an on-line application system for the distribution of biospecimens and a biobank accreditation program and is trying to harmonize the biobanks.

• 한국지역지리학회지
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• 제19권1호
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• pp.130-146
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• 2013

이 글은 다크투어리즘의 일환인 재난관광이 지닌 포스트모더니즘적 특성에 주목하여, 진정성 문제를 통해 이를 분석하는 것을 목적으로 하였다. 이를 위해 지난 2011년 발생한 동일본대지진을 구체적 사례로 선정하여, 재난관광의 전개 과정을 분석하였다. 재난 직후, 관광의 영역은 해체되고 일시적으로 재해 공동체가 형성된다. 이후 사회공헌형 관광이 등장하는데, 이 속에서 게스트(관광객)와 호스트(현지주민)는 모두 삶과 죽음의 문제를 공유하게 되고, 실존적 진정성은 관광동기와 경험에서 핵심요소가 된다. 그러나 시간이 지나면서 실존적 진정성은 재해재건의 정치경제적 맥락 속에서 이데올로기적으로 재편되고, 구성적 진정성으로 대체됨으로써 반근대적 성찰에 기반한 대안관광이라는 재난관광의 가능성에 한계가 나타나게 된다. 재난관광의 상품화 이면에 존재하는 윤리적 이슈를 고찰하기 위해서는 재난관광을 진정성 및 포스트모더니즘의 대안관광 틀 속에서 고찰하는 실증연구가 지속되어야 할 것이다.

• 기술혁신학회지
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• 제11권2호
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• pp.219-240
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• 2008

본 연구는 새로운 국가자원인 생물자원에 대한 최근의 국제적인 이슈와 주요국의 정책의지 및 관리 체계 등을 살펴 본 것이다. 그렇지만 논의의 전개를 위해 생물자원과 관련된 이론적인 논의, 역사 등을 먼저 검토하였다. 생물자원과 관련된 최근의 이슈는 지적재산권, 보관과 배송의 안전과 관련된 국제규약의 강화, 생물자원의 생물학적 표준강화, 생물자원센터의 윤리문제 등으로 특징지어진다. 이러한 논의를 바탕으로 본고는 생물자원정책의 방향, 체계 및 내용을 간단히 권고하였다. 특히 범부처적 차원에서의 생물자원의 관리와 확보를 위한 종합 조정과 시스템 구축의 필요성을 강조하였다.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제3권6호
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• pp.197-208
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• 2014

정보사회에 있어서 개인정보보호는 가장 중요한 윤리적 이슈 중 하나이다. 특히 업무특성상 진료를 목적으로 민감한 개인의 의료정보를 수집, 저장 및 처리하고 있는 의료기관의 경우 정보 유출시 개인의 사생활에 심각한 피해를 야기할 수 있다. 본 연구는 의료기관 소비자 관점에서 개인의료정보에 대한 일반적인 고객의 염려를 측정하기 위한 개인의료정보 프라이버시 염려 측정도구를 개발하고 타당도를 검증하는 것이다. 이를 위해 선행연구를 기초로 개인의료정보 프라이버시 염려 측정도구를 개발하였으며, 개발된 측정도구에 대한 탐색적 요인분석과 확인적 요인분석을 실시하여 신뢰도와 타당도를 검증하였다. 본 연구를 통해 개발된 측정도구는 국민의 개인의료정보보호에 대한 염려수준 및 관심 영역을 파악하여 적절한 개인정보보호 정책을 수립하는 데 유용하게 활용될 것으로 기대되며, 의료기관의 경우 의료서비스 소비자가 우려하는 해당 의료기관의 개인의료정보보호 문제점 및 그 수준을 파악하여 합리적인 대책을 도출하는 데 유용할 것으로 기대된다.

• 디지털융복합연구
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• 제19권10호
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• pp.367-376
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• 2021

본 연구는 작업치료사의 직업윤리와 교육에 대한 인식이 직무스트레스와 직무몰입에 미치는 영향을 파악하기 위한 조사연구이다. 이를 위하여 작업치료사 173명을 대상으로 직업윤리와 교육에 대한 인식, 직무스트레스와 직무몰입을 평가하였으며, 본 연구의 결과는 다음과 같다. 첫째, 직업윤리와 교육에 대한 인식, 직무스트레스와 직무몰입(p<.01) 간에는 유의한 상관관계가 있었다. 둘째, 직업윤리와 교육에 대한 인식의 하위요인 중 교육경험(p<.01)과 윤리문제의 심각성(p<.05)은 직무스트레스에 영향을 미치는 것으로 나타났다. 셋째, 직업윤리와 교육에 대한 인식의 하위요인 중 교육경험(p<.05)은 직무몰입에 영향을 미치는 것으로 나타났다. 본 연구의 결과들을 통하여 직업윤리의 중요성을 인식하고, 이를 향상하기 위한 체계적인 교육이 필요할 것이다.

• 철학연구
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• 제123호
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• pp.239-264
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• 2018

덕인식론과 지행론의 전체적인 구도를 이해하기 위한 선행 과제로서 나는 이 글에서 덕(德)과 관련한 개념들 가운데 역량과 성품이 지적 덕성과 어떤 연관에 놓여 있는지 정리하고자 한다. 애초 이 글은 똑똑하다고 칭찬받는 사람들이 왜 나쁜 일들을 스스럼없이 저지르는가에 대한 소박한 의문에서 출발한다. 이런 의문은 윤리적인 문제일 수도, 인식론적인 주제일 수도 있다. 왜냐하면무엇을 어떻게 인식할 것인가라는 인식론적인 질문은 결국 인식론이 규범적인영역에 속하며 인식론적인 평가에서 지적인 행위자와 그 공동체를 중시해야 한다는 것을 의미하기 때문이다. 이것은 '덕인식론'의 핵심적인 관점이다. 지식의정당화에 있어서 덕인식론이 '덕성'에 초점을 맞추고 있다는 점은 동아시아 전통의 '지행론'과 닮았지만 그 문제의식은 다르다. 따라서 덕인식론과 지행론의같고 다른 점을 우선 살펴보고 "논어"를 중심으로 역량, 성품, 지적 덕성의 관계를 검토할 것이다. 이 작업에서 나는 역량과 성품이 규범적인 가치의 문맥으로 조율되지 않으면 올바른 행위를 산출하는 지적 덕성이 되기에 부족함을 말할 것이다.

• 한국동물위생학회지
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• 제41권4호
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• pp.263-269
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• 2018

Developing drugs targeting respiratory pathogen is essential to control respiratory diseases. Many experiments have been performed under in vivo situation. However, in vivo experiments have economical and ethical issues. The objective of this study was to determine the possibility of developing an ex vivo lung culture system with possible application for respiratory infection studies. After isolating lungs from naïve pigs, agarose-inflated lung tissues were prepared and sliced manually. These sliced lung tissues were then subsequently placed on 24-well plates. Eight different combinations of media were used to determine the optimum ex vivo lung culture condition. In addition, lung tissues were infected with porcine reproductive and respiratory syndrome (PRRS) virus at a titer of $1{\times}10^4\;TCID_{50}/mL$. Virus growth was confirmed by titration in MARC-145 cells at 2, 4, 6 days post infection (dpi). We found that ex vivo lung culture in physiological environment was not media specific based on histopathology and cytotoxicity. However, under virus-infected condition, thickened alveolar walls in the lung tissues and stable virus titers at 2, 4, 6 dpi were shown in F12K medium suggesting that it was useful for tissue maintenance and virus infection using PRRS virus infected lung tissues. The present study shows the possibility of using porcine ex vivo lung model for respiratory infection studies.

• Laboraroty Animal Research
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• 제34권4호
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• pp.232-238
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• 2018

Animal models have been used to elucidate the pathophysiology of varying diseases and to provide insight into potential targets for therapeutic intervention. Although alternatives to animal testing have been proposed to help overcome potential drawbacks related to animal experiments and avoid ethical issues, their use remains vital for the testing of new drug candidates and to identify the most effective strategies for therapeutic intervention. Particularly, the study of metabolic diseases requires the use of animal models to monitor whole-body physiology. In line with this, the National Institute of Food and Drug Safety Evaluation (NIFDS) in Korea has established their own animal strains to help evaluate both efficacy and safety during new drug development. The objective of this study was to characterize the response of C57BL/6NKorl mice from the NIFDS compared with that of other mice originating from the USA and Japan in a chemical-induced diabetic condition. Multiple low-dose treatments with streptozotocin were used to generate a type-1 diabetic animal model which is closely linked to the known clinical pathology of this disease. There were no significantly different responses observed between the varying streptozotocin-induced type-1 diabetic models tested in this study. When comparing control and diabetic mice, increases in liver weight and disturbances in serum amino acids levels of diabetic mice were most remarkable. Although the relationship between type-1 diabetes and BCAA has not been elucidated in this study, the results, which reveal a characteristic increase in diabetic mice of all origins are considered worthy of further study.

• 연구윤리
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• 제2권2호
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• pp.21-24
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• 2021

Purpose: This paper aims to evaluate and reinstate preventative guidelines necessary for a sound academic journal (or academic conference) for the articles published by KODISA and its branch journals. As questionable or predatory academic journals and academic conferences are rapidly increasing, preemptively establishing preventative standards have become essential to obviate questionable academic activities. Research design, data and methodology: This is an analytical study that explores and examines research, publication ethics, and misconducts. For this purpose, research ethics related data in overseas and domestic academic journals have been examined and analyzed. Results: The issues identified from this research are as follows: enhancing the expertise of editor-inchief (no concurrent jobs for major and non-major area); clarifying the index; complying with the review policy (The review policy should be publicly announced); complying with anonymous review process; complying with 3 peer-review policy, complying with the publication policy as per field of study; avoiding conference hosting at holiday resorts unless unavoidable; complying with the planned programs and cancelling events if not feasible; following proper review standards and management for all journals, including the journals publishing large number of articles (all materials should be prepared in case explanatory data is required); complying with the marketing policy standards; complying with the impact factor; excluding personal solicitation; and complying with the general policy. Conclusions: Questionable and predatory academic activities by academic organizations and journals will continue, and it is the responsibility of the individual scholars to identify and reject these types of dubious academic activities. This study provides standards to prevent the possibility of questionable academic activities that have been conducted in the past. The analysis and findings will strengthen the continued efforts of KODISA as it strives to be a transparent, ethical, and professional academic association, and the association will continue to foster an academic environment that is well-respected by scholars and practitioners throughout the world.

• 한국임상보건과학회지
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• 제8권2호
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• pp.1426-1435
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• 2020

Objective: This study aims to develop CFT, a screening test for dementia that can be conducted on patients with mild cognitive impairment or early dementia. Methods: This study was conducted on therapists working at occupational therapy hospital in Gyeongsangnam-do. The data collection period is two months from July to September 2020, and the research participants were briefed on the purpose, significance, and anonymity of the research in consideration of ethical issues. A total of 33 copies of the data were finally analyzed, excluding those containing insufficient answers and errors, by distributing 40 copies of the data. SPSS Data Access pack 8.0 was used for data analysis, Cronbach's α value was evaluated for internal consistency reliability of each item, and Pearson Correlation coeffient between the lower scales of the assessment tool was measured. Results: The Cronbach's α value of the CFT was shown as .892 and the reliability of the assessment paper was shown to be quite high. The Cronbach's α value for each item in the cognitive assessment tool was the highest at .899 in the subtraction item, with exercise control (mook Chi Pa) at 888, visual memory, plus .887. The correlation of each item of cognitive assessment tools was found to be most correlated with the number of sustained concentrates and word2 to .934; in the stop word-numeric item and visual memory to be .85; and in the addition to the auditory memory item .739. Conclusion: Therefore, this study developed cognitive evaluation tools that can distinguish the diversity and cognitive level of screening tests and clarify standards, which are different from the existing dementia screening tools in Korea. Furthermore, the cognitive assessment tools of this study can be verified by applying them to patients with mild cognitive impairment and early dementia, and the criteria for generalization can be established.