• Title/Summary/Keyword: Estimating the validity

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A Rapid Method for Estimating the Levels of Urinary Thiobarbituric Acid Reactive Substances for Environmental Epidemiologic Survey

  • Kil, Han-Na;Eom, Sang-Yong;Park, Jung-Duck;Kawamoto, Toshihiro;Kim, Yong-Dae;Kim, Heon
    • Toxicological Research
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    • v.30 no.1
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    • pp.7-11
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    • 2014
  • Malondialdehyde (MDA), used as an oxidative stress marker, is commonly assayed by measuring the thiobarbituric acid reactive substances (TBARS) using HPLC, as an indicator of the MDA concentration. Since the HPLC method, though highly specific, is time-consuming and expensive, usually it is not suitable for the rapid test in large-scale environmental epidemiologic surveys. The purpose of this study is to develop a simple and rapid method for estimating TBARS levels by using a multiple regression equation that includes TBARS levels measured with a microplate reader as an independent variable. Twelve hour urine samples were obtained from 715 subjects. The concentration of TBARS was measured at three different wavelengths (fluorescence: ${\lambda}-_{ex}$ 530 nm and ${\lambda}-_{em}$ 550 nm; ${\lambda}-_{ex}$ 515 nm and ${\lambda}-_{em}$ 553 nm; and absorbance: 532 nm) using microplate reader as well as HPLC. 500 samples were used to develop a regression equation, and the remaining 215 samples were used to evaluate the validity of the regression analysis. The induced multiple regression equation is as follows: TBARS level (${\mu}M$) = -0.282 + 1.830 ${\times}$ (TBARS level measured with a microplate reader at the fluorescence wavelengths ${\lambda}-_{ex}$ 530 nm and ${\lambda}-_{em}$ 550 nm, ${\mu}M$) -0.685 ${\times}$ (TBARS level measured with a microplate reader at the fluorescence wavelengths ${\lambda}-_{ex}$ 515 nm and ${\lambda}-_{em}$ 553 nm, ${\mu}M$) + 0.035 ${\times}$ (TBARS level measured with a microplate reader at the absorbance wavelength 532 nm, ${\mu}M$). The estimated TBARS levels showed a better correlation with, and are closer to, the corresponding TBARS levels measured by HPLC compared to the values obtained by the microplate method. The TBARS estimation method reported here is simple and rapid, and that is generally in concordance with HPLC measurements. This method might be a useful tool for monitoring of urinary TBARS level in environmental epidemiologic surveys with large sample sizes.

Study on Measurement Condition Effects of CRP-based Structure Monitoring Techniques for Disaster Response (재해 대응을 위한 CRP기반 시설물 모니터링 기법의 계측조건 영향 분석)

  • Lee, Donghwan;Leem, Junghyun;Park, Jihwan;Yu, Byoungjoon;Park, Seunghee
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.30 no.6
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    • pp.541-547
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    • 2017
  • Climate change has become the main cause of the exacerbation in natural disasters. Social Overhead Capital(SOC) structure needs to be checked for displacement and crack periodically to prevent damage and the collapse caused by natural disaster and ensure the safety. For efficient structure maintenance, the optical image technology is applied to the Structure Health Monitoring(SHM). However, optical image is sensitive to environmental factors. So it is necessary to verify its validity. In this paper, the accuracy of estimating the vertical displacement was verified with respect to environmental condition such as natural light, measurement distance, and the number of image sheets. The result of experiments showed that the effect of natural light on accuracy of estimating vertical displacement was the greatest of all. The measurement angle which was affected by the change in measurement distance was also important to check the vertical displacement. These findings will be taken into account by applying appropriate environmental condition to minimize errors when the bridge was measured by camera. It will also enable the application of optical images to the SHM.

Scanning Determination & Observation Features by Sex shown in the Process of Acquiring Visual Information - With the Object of Subway Station Hall Space - (시각정보획득과정에 나타난 주사판정과 성별 주시특성 - 지하철 홀 공간을 대상으로 -)

  • Kim, Jong-Ha;Choi, Gae-Young
    • Korean Institute of Interior Design Journal
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    • v.23 no.6
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    • pp.115-124
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    • 2014
  • This study has carried out scanning tests in order to figure out the features of scanning search by sex of space users, with the result of which the validity of data has been estimated. In this research, the scanning patterns were set up for verifying the typology of scanning paths and then the reason for determining scanning paths and the validity of estimation method were reviewed. Since the observation features depends on sex, the analysis of visual activities for acquiring any information in a space will reveal the intention and purpose of space users. The findings by analyzing the features of scanning pattern by sex which were found at the determination of scanning patterns can be defined as the followings. First, for estimating the process of space-information search, the movement distance at each point of continuative-observation data from the angle of eye-movement has been extracted, on the ground of which the fixation and movement of eye have been defined for the establishment of scanning-cut characteristics. Second, the scanning times were estimated for the extraction of effective observation data that would be used for comparative analysis, which showed that men had more data (3,398.2/64.4%) than women (2,998.2/55.6%). This enables the acknowledgment that the scanning cut of men was relatively less, which indicates that men will acquire more information on space than women in the process of observing any space. Third, men's scanning times (58.0 times/2.02 seconds) were less than those of women (71.9 times/1.39 seconds) while the scanning time of the former was longer than that of the latter, which shows the feature that it takes longer for men than women in scanning while the scanning times of the former is less than those of the latter. Fourth, the observation features can be determined that the combination of this result with the predominance character by sex for a general viewpoint to be employed indicates that while men employ mixed-scanning for observation activities to acquire space-information spending for longer time, women, by concentrated-scanning, focus on a single point for shorter time or stay at one location for a considerably long time for space-information acquirement.

Relational Commitment, Performance, and the Franchiser's Management Characteristics and Fairness in Food Service Distribution (외식프랜차이즈 가맹본부의 관리특성과 공정성이 관계결속과 성과에 미치는 영향)

  • Kwon, Young-Sik;Mun, Jang-Sil;Kwon, Jae-Kuk
    • Journal of Distribution Science
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    • v.12 no.12
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    • pp.119-130
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    • 2014
  • Purpose - Franchise industries are significant both socially and economically. However, with increasing interest, there are manifold problems. It is necessary to seek measures for mature operation constantly despite unprepared franchisors, negative perceptions of the media and society toward franchise, and rapid changes in business start-up trends and propensity to consume that make business start-ups difficult. The paper aims to explain the effects of relational commitment and performance on the franchisor's management characteristics and justice in the food service franchise system. Research design, data, and methodology - This is an exploratory survey examining franchising in Korea. Based on a literature synthesis, we extract five constructs: managerial characteristics, support, fairness, trust, and satisfaction. We hypothesize that these factors influence the trust, satisfaction, and performance of franchisees. To examine these hypotheses empirically, we conducted a survey on the database of the Franchising Council of Korea. The study employs data from May to September 2014. In total, 135 completed questionnaires were received, of which 128 were usable. The data was analyzed with SPSS/PC 22.0. First, to test unidimensionality and nomological validity of the measures of each construct, we employed a scale refinement procedure. The result of a reliability test with Cronbach's α and factor analysis warranted unidimensionality of the measures for each construct. In addition, nomological validity of the measures was warranted from the result of the correlation and regression analysis. By analyzing the data, we can confirm most hypotheses. Results - Frist, franchisor characteristics have a positive effect on trust and satisfaction. Second, franchisor fairness has an effect on trust and satisfaction. Third, franchisor support has an effect on satisfaction. Further, the franchisee trust has an effect on satisfaction. Fourth, the satisfaction of a franchisee with a franchisor affects the performance of a franchisee. Finally, there is a possibility that not only franchisee performance but also increasing the credibility and improving the image of the franchisor through communication between franchisor and franchisee can improve franchisees' performance and satisfaction by motivating the franchisee for sustainable growth. Franchisers should endeavor for franchisees to obtain stable revenue with continuous and practical support. They should recognize that they can expand their business by supporting their franchisees. Franchisors should not only instantly respond to franchisees' troubles with interactive communications but also raise the ability of supervisors for better support. Franchisors should share their visions and goals with their franchisees and provide systematic and continuous support based on trust and clear company management. Franchisees should understand franchisors' position as well as participate in establishing the basic franchise system. Contributions - The paper contributes to understanding franchising in Korea. It offers insights and assistance to franchisors hoping to start franchises. This paper explores measurement issues related to franchisee performance by estimating its determinant factors (managerial characteristics, support, fairness, trust, and satisfaction). This study provides franchisors and practitioners planning to extend their franchising business with some practical knowledge.

Hypoxia Estimation of Coastal Bay through Estimation of Stratification Degree (성층강도 산정을 통한 내만의 Hypoxia 산정)

  • Jung, Woo-Sung;Lee, Won-Chan;Hong, Sok-Jin;Kim, Jin-Lee;Kim, Dong-Myung
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.20 no.5
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    • pp.511-525
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    • 2014
  • Goal of this study is estimating of validity of calculated vertical diffusion coefficient for Masan bay is semi-enclosed bay by using eco-hydrodynamic model that is used to analysis of physical structure of coastal waters and calculates the vertical diffusion coefficient. physical structure of coastal waters is calculated by EFDC model, vertical diffusion coefficient calculated as the density gradient is bigger, the vertical diffusion coefficient as density gradient is increases, the vertical diffusion coefficient is decreased. Validity of vertical diffusion coefficient estimated by reproducibility of concentration of dissolved oxygen that calculated in ecosystem model is constructed by Stella program. The Results of model in 2008~2009 were $R^2$ value of 2008 is 0.529~0.700 and $R^2$ value is 0.542~0.791. This results were similar to observed data and simulated to hypoxia at that time. The 'vertical diffusion coefficient' represents stratification and physical stable of a water body, and will be useful for prediction of Hypoxia outbreak.

The Reliability and Validity Studies of the Korean Version of the Perceived Stress Scale (한글판 스트레스 자각척도의 신뢰도와 타당도 연구)

  • Lee, Jongha;Shin, Cheolmin;Ko, Young-Hoon;Lim, JaeHyung;Joe, Sook-Haeng;Kim, SeungHyun;Jung, In-Kwa;Han, Changsu
    • Korean Journal of Psychosomatic Medicine
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    • v.20 no.2
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    • pp.127-134
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    • 2012
  • Objectives : Perceived stress scale is a self-report inventory to estimate the degree of individual perceived stress in daily life. The aim of this study was to introduce this scale and test the reliability and validity of the Korean version of PSS. Methods : The total of 154 female hospital workers were included in this study. The survey questionnaires were conducted for demographic information. All participants were required to complete PSS, Hamilton Anxiety scale and Beck Depression Inventory. Reliability and validity studies were conducted and internal consistency was examined. Results : The mean score of the PSS reported in this sample was $20.69{\pm}4.56$. The overall Cronbach's alpha was 0.819, and the test-retest reliability coefficient was 0.66. PSS had a significant positive correlation with the HAM-A(r=0.49, p<0.01), and the BDI(r=0.55, p<0.01). Factor analysis yielded 2 factors with eigenvalues of 3.924 and 2.608, accounting for 65 percent of variance. Factor 1 represented "stress" and factor 2 represented "control of stress". Conclusions : This study indicates that the PSS is appropriate for estimating the perceived stress levels. These results support the use of PSS in large sections of the population in Korea.

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Risk assessment for inland flooding in a small urban catchment : Focusing on the temporal distribution of rainfall and dual drainage model (도시 소유역 내 내수침수 위험도 평가 : 강우 시간분포 및 이중배수체계 모형을 중심으로)

  • Lee, Jaehyun;Park, Kihong;Jun, Changhyun;Oh, Jeill
    • Journal of Korean Society of Water and Wastewater
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    • v.35 no.6
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    • pp.389-403
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    • 2021
  • In this study, dual drainage system based runoff model was established for W-drainage area in G-si, and considering the various rainfall characteristics determined using Huff and Mononobe methods, the degree of flooding in the target area was analyzed and the risk was compared and analyzed through the risk matrix method. As a result, the Monobe method compared to the Huff method was analyzed to be suitable analysis for flooding of recent heavy rain, and the validity of the dynamic risk assessment considering the weight of the occurrence probability as the return period was verified through the risk matrix-based analysis. However, since the definition and estimating criteria of the flood risk matrix proposed in this study are based on the return period for extreme rainfall and the depth of flooding according to the results of applying the dual drainage model, there is a limitation in that it is difficult to consider the main factors which are direct impact on inland flooding such as city maintenance and life protection functions. In the future, if various factors affecting inland flood damage are reflected in addition to the amount of flood damage, the flood risk matrix concept proposed in this study can be used as basic information for preparation and prevention of inland flooding, as well as it is judged that it can be considered as a major evaluation item in the selection of the priority management area for sewage maintenance for countermeasures against inland flooding.

Validity of the dietary reference intakes for determining energy requirements in older adults

  • Ndahimana, Didace;Go, Na-Young;Ishikawa-Takata, Kazuko;Park, Jonghoon;Kim, Eun-Kyung
    • Nutrition Research and Practice
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    • v.13 no.3
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    • pp.256-262
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    • 2019
  • BACKGROUND/OBJECTIVES: The objectives of this study were to evaluate the accuracy of the Dietary Reference Intakes (DRI) for estimating the energy requirements of older adults, and to develop and validate new equations for predicting the energy requirements of this population group. MATERIALS/METHODS: The study subjects were 25 men and 23 women with a mean age of $72.2{\pm}3.9\;years$ and $70.0{\pm}3.3\;years$, and mean BMI of $24.0{\pm}2.1$ and $23.9{\pm}2.7$, respectively. The total energy expenditure (TEE) was measured by using the doubly labeled water (DLW) method, and used to validate the DRI predictive equations for estimated energy requirements (EER) and to develop new EER predictive equations. These developed equations were cross-validated by using the leave-one-out technique. RESULTS: In men, the DRI equation had a -7.2% bias and accurately predicted the EER (meaning EER values within ${\pm}10%$ of the measured TEE) for 64% of the subjects, whereas our developed equation had a bias of -0.1% and an accuracy rate of 84%. In women, the bias was -6.6% for the DRI equation and 0.2% for our developed equation, and the accuracy rate was 74% and 83%, respectively. The predicted EER was strongly correlated with the measured TEE, for both the DRI equations and our developed equations (Pearson's r = 0.915 and 0.908, respectively). CONCLUSIONS: The DRI equations provided an acceptable prediction of EER in older adults and these study results therefore support the use of these equations in this population group. Our developed equations had a better predictive accuracy than the DRI equations, but more studies need to be performed to assess the performance of these new equations when applied to an independent sample of older adults.

Economical & Technological Ripple Effects in Acquiring New Weapon System : Focused on Ground·Sea·Air Weapon System (국방무기체계 연구개발 기반 경제적·기술적 파급효과 : 지상·해상·공중 무기체계를 중심으로)

  • Shin, Sang-Wook;Oh, Cheon-Kyun;Yim, Dong-Soon;Choi, Bong-Wan
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.41 no.4
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    • pp.111-122
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    • 2018
  • The private sector is currently reviewing the feasibility of the project or deciding economic policies by analyzing the economic ripple effects. However, the arms acquisition project focuses on the need for the national defense weapons system by analyzing the costs and the effectiveness of the analysis and reviewing the necessity and feasibility of the project. In order to analyze the economic ripple effects, KB (the Bank of Korea) prepares and publishes an analysis table of industrial associations in a given unit. IAAR (the industrial association analysis report) is difficult to apply directly to the defense weapons system. Therefore, research on the economic ripple effects applicable to the defense arms procurement project was needed. In this study, we propose the generic methodology for estimating economical and technical ripple effects resulted in acquiring new weapon systems. Based on the analysis of inter-industrial relations, economical ripple effects are estimated with production inducing effects, value-induced effects, employment-induced effects and export-induced effects. Also, the technological ripple effects are estimated with technological intensity represented by investment cost in research and development. To show the validity of proposed methodology, a case study of acquiring new weapon systems such as GR (guided rocket), destroyer, and helicopter is accomplished. From the case study, it is concluded that these economical & technological ripple effects can be used as a reference to decision making in the course of acquiring major future defense weapons systems.

Tension Measurement of Stay Cables in Consideration with Image Including Vehicle (차량이 포함된 이미지를 고려한 사장재 케이블의 장력 측정 )

  • Sung-Wan Kim;Dong-Uk Park;Jin-Soo Kim;Seung-Su Park;Jae-Bong Park
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.27 no.2
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    • pp.58-66
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    • 2023
  • In this study, cable tension was measured using the vibration method, and a vision-based system was applied as a sensor to measure the displacement response of a cable in a non-contact method. In the vision-based system, the camera is installed in a location that considers the target structure and the field of view of the camera. However, it can be difficult to recognize the control points required to measure the displacement response of a structure as the target structure and other structures such as vehicles may be included in the image at the intended installation location. In this study, a distorted image including a vehicle shows inaccurate results in image analysis due to the installation position of the vision-based system. Accordingly, the image including the vehicle was eliminated by calculating the similarity between the two images. To verify the validity of the method of estimating the cable tension of cable-stayed bridges using the proposed method, the vibration method was applied to cable-stayed bridges in service to measure the tension.