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Characterization of Differentiation of the Supernumerary Dental Pulp Stem Cells toward the Odontoblast by Application Period of Additives (과잉치 치수유래 줄기세포의 분화제 처리 기간에 따른 상아모세포 발현 특성)

  • Kim, Jongsoo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.42 no.4
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    • pp.312-318
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    • 2015
  • The aim of this study was to investigate the possibility of the supernumerary teeth for the stem cell source in dentistry. The Real Time Quantitative Reverse Transcription Polymerase Chain Reaction (Real Time qRT-PCR) method was used to evaluate the differentiation toward the odontoblast of the supernumerary dental pulp stem cells (sDPSCs). Supernumerary dental pulp stem cells were obtained from 3 children (2 males and 1 female, age 7 to 9) diagnosed that the eruption of permanent teeth was disturbed by supernumerary teeth. The common genes for odontoblasts are alkaline phosphatase (ALP), osteocalcin (OC), osteonectin (ON), dentin matrix acidic phosphoprotein 1 (DMP-1), dentin sialophosphoprotein (DSPP). The sDPSCs were treated for 0 days, 8 days and 14 days with additives and then Real Time qRT-PCR was performed in intervals of 0 days, 8 days and 14 days. The alizarin-red solution staining was performed to visualize the stained color for the degree of calcification at 7 days, 14 days, 21 days and 28 days after treating additives to the sDPSCs. From the result of the Real Time qRT-PCR, the manifestation exhibit maximum value at 8 days after additive treatment and shifted to a decrease trend at 14 days. Alizarin-red solution staining exhibit light results at 7 days after staining and generalized dark result at 14 days. Consequently, in studies with sDPSCs, appropriate treatment time of additives for Real Time qRT-PCR is 8 days. Also, a suitable period of Alizarin-red solution staining is 14 days.

An Alternative Explanation for Anti-Japanese Sentiment in China: Shifting State-Society Interaction in China's Japan Policy

  • Zhou, Min
    • Journal of Contemporary Eastern Asia
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    • v.11 no.2
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    • pp.61-75
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    • 2012
  • The historical turbulence between China and Japan started from the First Sino-Japanese War in 1895, and culminated in Japan's invasion of China during World War Two (the Second Sino-Japanese War) between 1937 and 1945. A series of wars caused huge human and material losses in both countries, and both experienced comprehensive transformations during and after the wars. The impact of this historical turbulence is so long-lasting that it still influences both countries' social psyche. Moreover, it continues casting a long shadow upon the current Sino-Japanese relations. The recent turbulence in Sino-Japanese relations partly stems from the historical turbulence. It is much less violent but can also be emotional and worrisome. It started from the early 1980s (the Japanese history textbook controversy in 1982 and the 1985 anti-Japanese student protests in China), and culminated in the anti-Japanese mass demonstrations in multiple Chinese cities in 2005 (Bush 2010; Gries 2005; Reilly 2012; Stockmann 2010; Weiss 2008). In addition to dramatic demonstrations on streets, there are also other forms of movements, such as war reparations movements, in which Chinese war victims demand reparations from the Japanese state and companies (Rose 2005; Xu and Fine 2010; Xu and Pu 2010). Although the tension has existed for many years and surfaced from time to time, the eruption of the nationwide anti-Japanese movements in China in 2005 still shocked many outside observers. Many scholars have tried to explain the anti-Japanese sentiment within current Chinese society that underlies and drives these social movements. Through careful reexamination of the existing literature, this article proposes an explanation for the anti-Japanese sentiment from a perspective that stresses the shifting state-society interaction in China's Japan policy. Specifically, the totalitarian Chinese state's neglect and suppression of genuine social concerns regarding Japan in earlier years, followed by a relatively liberalized state that tolerates societal participation in Sino-Japanese relations, are an importance source of the anti-Japanese sentiment recently observed in China.

Priority Data Handling in Pipeline-based Workflow (파이프라인 기반 워크플로우의 우선 데이터 처리 방안)

  • Jeon, Wonpyo;Heo, Daeyoung;Hwang, Suntae
    • KIISE Transactions on Computing Practices
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    • v.23 no.12
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    • pp.691-697
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    • 2017
  • Volcanic ash has been predicted to be the main source of damage caused by a potential volcanic disaster around Mount Baekdu and the regions of the Korean peninsula. Computer simulations to predict the diffusion of volcanic ash should be performed according to prevalent meteorological situations within a predetermined time. Therefore, a workflow using pipelining is proposed to parallelize the software used for this computation. Due to the nature of volcanic calamities, the simulations need to be carried out for various plausible conditions given that the parameters cannot be precisely determined during the simulations, even at the time of a volcanic eruption. Among the given conditions, computations need to be first performed for the condition with the highest probability so that a response to the volcanic disaster can be provided using these results. Further action can then be performed later based on subsequent results. The computations need to be performed using a volcanic disaster damage prediction system on a computing server with limited computing performance. Hence, an optimal distribution of the computing resources is required. We propose a method through which specific data can be provided first to the proposed pipeline-based workflow.

DIAGNOSIS AND TREATMENT PLAN OF MAXILLARY IMPACTED CANINE (상악매복견치의 진단 및 처치)

  • Kyung, Seung-Hyun;Hwang, Chung-Ju
    • The korean journal of orthodontics
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    • v.23 no.2 s.41
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    • pp.165-177
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    • 1993
  • Upper canine is important because it protects and maintains the stability of the dental arch and also, joins the anterior with the posterior teeth. The incidence of impaction of upper canine is the second most frequent next to the third molar because it takes a long period of time to develop, and has a complicated path of eruption, and erupts lately. After the age of 10, clinical and radioglaphic examination can be used in revealing the possibility of impaction and efforts should be put to reduce the side effects. To prevent impaction, selective extraction of primary canine at the age of 8 to 9 could be considered and prolonged retention of primary canine in oral cavity should be avoided at this time. Once the impaction is iden, the first stage of the treatment is to lcocalize the lesion by radiographic examination and According to the severity, orthodontic traction or autotransplantation should be considered and comprehensive diagnosis and treatment plan of malocclusion should be established. Generally, labial impaction is due to arch length discrepancy and palatal impaction is due to malposition or morphologic pathosis of lateral incisors rather than arch length discrepancy. In surgical procedure, peridontal problems should be considered and the minimum amount of bone and soft tissue should be reduced and direct bonding method of many attachment methods should be recommended. Especially in traction of labially impacted canine, it should be guided to erupt through the keratinized zone and proper forced magnitude should be applied. The importance of periodontal condition should always be in mind following the patient education to mintain the good oral hygiene at each stage of treatment. Properly managed impacted canine can provide function and esthetic by proper diagnosis and treatment if extraction of canine is not indicated.

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SHRIMP U-Pb Dating and Volcanic History of the Jipum Volcanics, Western Yeongdeok, Korea (영덕 서부 지품화산암층의 SHRIMP U-Pb 연대측정과 화산과정)

  • Hwang, Sang Koo
    • The Journal of the Petrological Society of Korea
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    • v.26 no.4
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    • pp.341-352
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    • 2017
  • The Jipum Volcanics, occurred in western Yeongdeok, are a stratigraphic unit that is composed of rhyolitic pyroclastic rocks, tuffites, andesitic hyaloclastites, rhyolite lavas, tuffaceous conglomerates and andesite lavas. The SHRIMP U-Pb zircon dating yielded eruption ages of $68.5{\pm}1.6Ma$ from the rhyolitic pyroclastic rocks. Around the time, the unit was generated by dominant rhyolitic volcanisms and locally added by concomitant andesitc volcanisms from another vents. The rhyolitic volcanisms first produced the pyroclastic rocks by phreatomagmatic explosions from rhyolitic magma, later made of the rhyolite lava dome by lava effusions from reopening of the rhyolitc magma at the existing vent. At the time between first and second rhyolitic volcanisms, the tuffites were deposited at a shallow depression in the distal volcanic edifice, and andesitic volcanisms first made of the hyaloclastites by quench fragmentation when hot andesite lavas flew into the depression to contact with cold water. and the Jipum volcano was finally covered with the thin andesitic lavas by lava effusions from another vent.

Effect of the Nishinoshima Volcanic Eruption on Fine Particulate Concentration in Busan in Early August 2020 (일본 니시노시마 화산 분출이 2020년 8월 초 부산지역의 미세먼지 농도에 미치는 영향)

  • Byung-Il Jeon
    • Journal of Environmental Science International
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    • v.31 no.12
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    • pp.1079-1087
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    • 2022
  • This study investigated the effect of volcanic materials that erupted from the Nishinoshima volcano, Japan, 1,300 km southeast of the Busan area at the end of July 2020, on the fine particle concentration in the Busan area. Backward trajectory analysis from the HYSPLIT model showed that the air parcel from the Nishinoshima volcano turned clockwise along the edge of the North Pacific high pressure and reached the Busan area. From August 4 to August 5, 2020, the concentration of PM10 and PM2.5 in Busan started to increase rapidly from 1000 LST on August 4, and showed a high concentration for approximately 13 hours until 2400 LST. The PM2.5/PM10 ratio showed a relatively high value of 0.7 or more, and the SO2 concentration also showed a high value at the time when the PM10 and PM2.5 concentrations were relatively high. The SO42- concentration in PM2.5 in Busan showed a similar trend to the change in PM10 and PM2.5 concentrations. It rose sharply from 1300 LST on August 4, at the time where it was expected to have been affected by the Nishinoshima Volcano. This study has shown that the occurrence of high concentration fine particle in Busan in summer has the potential to affect Korea not only due to anthropogenic factors but also from natural causes such as volcanic eruptions in Japan.

The Study of Formation for Dokdo Seamounts at the Northeastern Part of the Ulleung Basin Using Gravity and Magnetic Data (중력 및 자력자료 분석에 의한 울릉분지 북동부 독도 및 주변 해산들의 형성 연구)

  • Kim, Chang-Hwan;Park, Chan-Hong;Ko, Young-Tak;Jung, Eui-Young;Kwak, Jun-Young;Yoo, Sang-Hoon;Min, Kyung-Duck
    • Economic and Environmental Geology
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    • v.40 no.2 s.183
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    • pp.153-170
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    • 2007
  • Loading time and loading environment of the Dokdo seamounts were studied from flexure model and VGP(Virtual Geomagnetic Pole) determined by gravity and magnetic data. In spite of their similarity in size. a large difference about 50 mGal between gravity anomaly peaks of Dokdo and the Isabu Tablemount suggests different compensation degrees. Flexural modeling results show that the flexural rigidity(effective elastic thickness) of lithosphere for Dokdo is stronger(thicker) than that for the Isabu Tablemount. Also, it implies that the age of lithosphere at the time of loading of the Isabu Tablemount may be younger than that of Dokdo. Magnetic anomalies occur complicated over the Dokdo seamounts. Paleomagnetism was studied from VGP estimated by the least square and the seminorm magnetization methods with 1500 m upward continued magnetic anomalies. Age dating of Dokdo from previous study, flexural modeling, VGP, and geomagnetic polarity time scale suggest that after the cease of spreading in the Ulleung Basin, the Isabu Tablemount was formed first in normal polarity interval and followed by Dokdo. Also, they indicate that the fist large eruption of Dokdo was in normal polarity interval and the second large eruption in reversed polarity interval. The Simheungtaek Tablemount was formed in normal polarity interval between the formations of the Isabu Tablemount and Dokdo. These loading times for the Dokdo seamounts show a good coherence with the compressive stress period after the end of the opening of the East Sea. The Dokdo seamounts probably was caused by volcanism associated with the compressive stress.

Timing for Removal of Mesiodens in Relation to the Maxillary Cental Incisors (과잉치 발거시기에 따른 상악 중절치의 위치 변화)

  • Park, Kibong;Lee, Daewoo;Kim, Jaehwan;Yang, Yeonmi;Kim, Jaegon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.43 no.3
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    • pp.246-253
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    • 2016
  • The optimal time for the removal of supernumerary teeth can be divided into two groups; early removal and late removal. While each group has its own advantages, the effects on maxillary central incisor can be significant. The purpose of this study was to determine the ideal time for the removal of the supernumerary teeth by evaluating 166 patients for three months after surgical removal of supernumerary teeth. Relatively young patients in early Hellman's dental stage with less developed or unerupted maxillary central incisor had less midline deviation. No statistical significance was found in diastema, rotation of the maxillary incisors and their changes during a follow-up period. Removal of supernumerary teeth should be considered as a preventative measure prior to eruption of the maxillary incisors when the midline deviation is observed in panoramic radiographic examination. This study will be useful in determining the optimal time for the removal of supernumerary teeth depending on the location of the maxillary incisors. This study will be informative on deciding the optimal time to remove the supernumerary teeth depending on the various positions of the maxillary central incisor. (this sentence is better to use)

Effect of Jeseupwiryeongtang-Kamibang(JWRTK) on atopic dermatitis-like skin lesions induced in NC/Nga mice by mite antigen stimulation (제습위령탕가미방(除濕胃笭湯加味方)이 NC/Nga mice의 아토피 발진 억제에 미치는 실험적 연구)

  • Na, Dong-Kyu;Kim, Yun-Hee;Han, Jae-Kyung;Kim, Yun-Hee
    • Journal of Haehwa Medicine
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    • v.16 no.1
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    • pp.93-105
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    • 2007
  • Objective : We wished to examine closely effect that Kami-JeSeubUilYeongTang medicines used to atopy dermatitis disease patient get in atopy eruption control experimentally. Materials and Methods : Atopic dermatitis (AD) usually develops in patients with an individual or family history of allergic diseases, and is characterized by chronic relapsing inflammation seen specially in childhood, association with IgE hyperproduction and precipitation by environmental factors. However, the exact etiology of AD has been unclear. To further explore the pathogenesis and treatment of AD, a suitable animal model is required. We found that skin lesions, which were clinically and histologically very similar to human AD, mite antigen-induced dermatitis on the face, neck, ears and dorsal skin of inbred NC/Nga mice. Result and Conclusion : Kami-jeseupwiryeongtang(JWRTK) medicines controlled CD3+/CD69+, CD4+/CD25+, B220+/IgE+, and B220+/CD23+ revelation that an experiment that motive allergy immune reponse because an in vitro experiment stimulates splenocytes of a NC/Nga mouse same time by PWM, and interleukin-4, eotaxin 2, CCR3, TARC mRNA outturn that bear in splenocytes decreased remarkably by Jeseupwiryeongtang-Kamibang(JWRTK) medicines. Th1 cell and Th2 cell observe to be shifted by secretion amount of IL-4 and IFN-$\gamma$ by Jeseupwiryeongtang-Kamibang(JWRTK) medicines could know that Jeseupwiryeongtang-Kamibang(JWRTK) medicines can use usefully in allergy autoimmnune diease.

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Analysis of Factors that Affect the Follow-up Pattern after Dental Treatment under Conscious Sedation in Children (어린이의 진정법 하 치과치료 후 정기검진에 영향을 미치는 요인 분석)

  • Hwang, Inkyung;Mah, Yonjoo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.45 no.3
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    • pp.324-333
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    • 2018
  • Children need regularly dental check-ups after dental treatment because there are a lot of changes of oral conditions such as tooth exfoliation and eruption, occlusion, and recurrence of dental caries. The purpose of this study is to determine the factors that affect the follow-up pattern after dental treatment under conscious sedation. Patients who were treated under sedation at the department of pediatric dentistry of Ewha Womans University Mokdong Hospital from 2009 to 2013 were included in this study. The final samples comprised of 562 patients that were classified into 4 groups according to the number of visits during 3 years. The chi-square test was used to determine the factors affecting regular follow-up. There were statistically significant differences between each treatment groups and factors such as the change of doctor, overall treatment time, the number of treated teeth under sedation, restorative treatment, minor operation, and preventive treatment (p < 0.05). This study identified factors that affect regular follow-up after dental treatment under conscious sedation. It is recommended to educate the importance of regular check-ups to parents who are less likely to return.