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Radiotherapic Valuation of Paraffin Wax for Patients with Oral Cancer (구강암 환자 치료시 치과용 기초상 왁스(Paraffin Wax)의 유용성 평가)

  • Na, Kyoung-Su;Seo, Seuk-Jin;Lee, Je-Hee;Yoo, Sook-Heun
    • The Journal of Korean Society for Radiation Therapy
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    • v.23 no.1
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    • pp.41-49
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    • 2011
  • Purpose: This study is designed to investigate radiotherapic valuation of Paraffin Wax, which is newly formed for this study and generally utilized in dentistry, and Mouth Piece and Putty impression, which are commonly used in radiotherapy, for oral cavity as a compensator. Materials and Methods: Each compensator was formed by $10{\times}10{\times}1cm$ and measured radiation dose attenuation ratio with reference of water phantom which is made of tissue-equivalent materials. Two patients with oral cancer underwent DRR (Digitally Reconstructed Radiogrph) of Offline Review Program of Aria System and Portal vision for 5 times for each material to evaluate reproducibility by each filling materials. Moreover, MU (monitor unit) changes by dose absorption were considered in the case of inevitable implication of an filling materials in the range for radiotherapy. Results: Radiation dose attenuation ratios were shown -0.7~+3.7% for Mouth Piece, +0.21~+0.39% for Paraffin Wax and -2.71~-1.76% for Putty impression. Error ranges of reproducibility of positions were measured ${\pm}3mm$ for Mouth Piece, ${\pm}2mm$ for Paraffin Wax and ${\pm}2mm$ mm for Putty impression. Difference of prescription MU from dose absorption with an filling material increased +7.8% (250 MU) in Putty impression and -0.9% (230 MU) in Paraffin Wax as converted into a percentage from the standard phantom, Water 232 MU. Conclusion: Dose reduction of boundary between cavity and tissue was observed for Mouth Piece. Mouth Piece also had low reproducibility of positions as it had no reflection of anatomy of oral cavity even though it was a proper material to separate Maxilla and Mandible during therapy. On the other hand, Putty impression was a suitable material to correctly re-position oral cavity as before. However, it risked normal tissues getting unnecessary over irradiation and it caused radiation dose decrease by -2.5% for 1cm volume in comparison of it of water phantom. Dose reduction in Paraffin Wax, Fat Tissue-Equivalent Material, was smaller than other impressions and position reproducibility of it was remarkable as it was possible to make an anatomy reflected impression. It was also well fitted to oral cavity to transfer radiation dose planned in radiotherapy. Thus, Paraffin Wax will be an ideal material in radiotherapy for patients with oral cancer.

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Predictive Modeling of Bacillus cereus on Carrot Treated with Slightly Acidic Electrolyzed Water and Ultrasonication at Various Storage Temperatures (미산성 차아염소산수와 초음파를 처리한 당근에서 저장 중 Bacillus cereus 균의 생육 예측모델)

  • Kim, Seon-Young;Oh, Deog-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.8
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    • pp.1296-1303
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    • 2014
  • This study was conducted to develop predictive models for the growth of Bacillus cereus on carrot treated with slightly acidic electrolyzed water (SAcEW) and ultrasonication (US) at different storage temperatures. In addition, the inactivation of B. cereus by US with SAcEW was investigated. US treatment with a frequency of 40 kHz and an acoustic energy density of 400 W/L at $40^{\circ}C$ for 3 min showed the maximum reduction of 2.87 log CFU/g B. cereus on carrot, while combined treatment of US (400 W/L, $40^{\circ}C$, 3 min) with SAcEW reached to 3.1 log CFU/g reduction. Growth data of B. cereus on carrot treated with SAcEW and US at different temperatures (4, 10, 15, 20, 25, 30, and $35^{\circ}C$) were collected and used to develop predictive models. The modified Gompertz model was found to be more suitable to describe the growth data. The specific growth rate (SGR) and lag time (LT) obtained from the modified Gompertz model were employed to establish the secondary models. The newly developed secondary models were validated using the root mean square error, bias factor, and accuracy factor. All results of these factors were in the acceptable range of values. After compared SGR and LT of B. cereus on carrot, the results showed that the growth of B. cereus on carrot treated with SAcEW and US was slower than that of single treatment. This result indicates that shelf life of carrot treated with SAcEW and US could be extended. The developed predictive models might also be used to assess the microbiological risk of B. cereus infection in carrot treated with SAcEW and US.

Numerical Prediction for Fluidized Bed Chlorination Reaction of Ilmenite Ore (일메나이트광의 유동층 염화반응에 대한 수치적 예측)

  • Chung, Dong-Kyu;Jung, Eun-Jin;Lee, Mi Sun;Kim, Jinyoung;Song, Duk-Yong
    • Clean Technology
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    • v.25 no.2
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    • pp.107-113
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    • 2019
  • Numerical model that considered the shrinking core model and elutriation and degradation of particles was developed to predict selective chlorination of ilmenite and carbo-chlorination of $TiO_2$ in a two stage fluidized bed chlorination furnace. It is possible to analyze the fluidized bed chlorination reaction to be able to reflect particle distribution for mass balances and the chlorination reaction. The numerical model showed an accuracy with error less than 6% compared with fluidized bed experiments. The chlorination degree with particle size change was greater with a smaller particle size, and there was a 100 min difference to obtain a chlorination degree of 1 between $75{\mu}m$ and $275{\mu}m$. This was not shown to such a great extent with variation of temperature ($800{\sim}1000^{\circ}C$), and there was only a 10 min difference to obtain a chlorination degree of 0.9. In the first selective chlorination process, the mass reduction rate approached to the theoretical value of 0.4735 after 180 min, and chlorination changed the Fe component into $FeCl_2$ or $FeCl_3$ and showed nearly 1. In the second carbo-chlorination process, the chlorination degree of $TiO_2$ approached 0.98 and the mass fraction reached 0.02 with conversion into $TiCl_4$. In the first selective chlorination process, 98% of $TiO_2$ was produced at 180 min, and this was changed into 99% of $TiCl_4$ after an additional 90 min. Also the mass reduction rate of $TiO_2$ was reduced to 99% in the second continuous carbo-chlorination process.

Comparison and evaluation between 3D-bolus and step-bolus, the assistive radiotherapy devices for the patients who had undergone modified radical mastectomy surgery (변형 근치적 유방절제술 시행 환자의 방사선 치료 시 3D-bolus와 step-bolus의 비교 평가)

  • Jang, Wonseok;Park, Kwangwoo;Shin, Dongbong;Kim, Jongdae;Kim, Seijoon;Ha, Jinsook;Jeon, Mijin;Cho, Yoonjin;Jung, Inho
    • The Journal of Korean Society for Radiation Therapy
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    • v.28 no.1
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    • pp.7-16
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    • 2016
  • Purpose : This study aimed to compare and evaluate between the efficiency of two respective devices, 3D-bolus and step-bolus when the devices were used for the treatment of patients whose chest walls were required to undergo the electron beam therapy after the surgical procedure of modified radical mastectomy, MRM. Materials and Methods : The treatment plan of reverse hockey stick method, using the photon beam and electron beam, had been set for six breast cancer patients and these 6 breast cancer patients were selected to be the subjects for this study. The prescribed dose of electron beam for anterior chest wall was set to be 180 cGy per treatment and both the 3D-bolus, produced using 3D printer(CubeX, 3D systems, USA) and the self-made conventional step-bolus were used respectively. The surface dose under 3D-bolus and step-bolus was measured at 5 measurement spots of iso-center, lateral, medial, superior and inferior point, using GAFCHROMIC EBT3 film (International specialty products, USA) and the measured value of dose at 5 spots was compared and analyzed. Also the respective treatment plan was devised, considering the adoption of 3D-bolus and stepbolus and the separate treatment results were compared to each other. Results : The average surface dose was 179.17 cGy when the device of 3D-bolus was adopted and 172.02 cGy when step-bolus was adopted. The average error rate against the prescribed dose of 180 cGy was -(minus) 0.47% when the device of 3D-bolus was adopted and it was -(minus) 4.43% when step-bolus was adopted. It was turned out that the maximum error rate at the point of iso-center was 2.69%, in case of 3D-bolus adoption and it was 5,54% in case of step-bolus adoption. The maximum discrepancy in terms of treatment accuracy was revealed to be about 6% when step-bolus was adopted and to be about 3% when 3D-bolus was adopted. The difference in average target dose on chest wall between 3D-bolus treatment plan and step-bolus treatment plan was shown to be insignificant as the difference was only 0.3%. However, to mention the average prescribed dose for the part of lung and heart, that of 3D-bolus was decreased by 11% for lung and by 8% for heart, compared to that of step-bolus. Conclusion : It was confirmed through this research that the dose uniformity could be improved better through the device of 3D-bolus than through the device of step-bolus, as the device of 3D-bolus, produced in consideration of the contact condition of skin surface of chest wall, could be attached to patients' skin more nicely and the thickness of chest wall can be guaranteed more accurately by the device of 3D-bolus. It is considered that 3D-bolus device can be highly appreciated clinically because 3D-bolus reduces the dose on the adjacent organs and make the normal tissues protected, while that gives no reduction of dose on chest wall.

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A Study on the Patient Exposure Doses from the Panoramic Radiography using Dentistry (치과 파노라마 촬영에서 환자의 피폭선량에 관한 연구)

  • Park, Ilwoo;Jeung, Wonkyo;Hwang, Hyungsuk;Lim, Sunghwan;Lee, Daenam;Im, Inchul;Lee, Jaeseung;Park, Hyonghu;Kwak, Byungjoon;Yu, Yunsik
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.17-24
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    • 2013
  • This study estimate radiation biological danger factor by measuring patient's exposed dose and propose the low way of patient's exposed dose in panoramic radiography. We seek correcting constant of OSL dosimeter for minimize the error of exposed dose's measurement and measure the Left, Right crystalline lens, thyroid, directly included upper, lower lips, the maxillary bone and the center of photographing that indirect included in panoramic radiography by using the human body model standard phantom advised in ICRP. In result, the center of photographing's level of radiation maximum value is $413.67{\pm}6.53{\mu}Gy$ and each upper, lower lips is $217.80{\pm}2.98{\mu}Gy$, $215.33{\pm}2.61{\mu}Gy$. Also in panoramic radiography, indirect included Left, Right crystalline lens's level of radiation are $30.73{\pm}2.34{\mu}Gy$, $31.87{\pm}2.50{\mu}Gy$, and thyroid's level of measured exposed dose can cause effect of radiation biological and we need justifiable analysis about radiation defense rule and substantiation advised international organization for the low way of patient's exposed dose in panoramic radiography of dental clinic and we judge need the additional study about radiation defense organization for protect the systematize protocol's finance and around internal organs for minimize until accepted by many people that is technological, economical and social fact by using panoramic measurement.

Evaluate the Change of Body Shape and the Patient Alignment State During Image-Guided Volumetric Modulated Arc Therapy in Head and Neck Cancer Patients (두경부 환자의 VMAT 시 체형변화와 환자 정렬과의 상관관계 고찰)

  • Seo, Se Jeong;Kim, Tae Woo;Choi, Min Ho;Son, Jong Gi
    • The Journal of Korean Society for Radiation Therapy
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    • v.29 no.2
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    • pp.109-117
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    • 2017
  • Objectives: The purpose of this study was to evaluate the change of body shape and the patient alignment state during image-guided volumetric modulated arc therapy in head and neck cancer patients, Materials and Methods: We performed a image-guided volumetric modulated arc therapy plan for 89 patients with head and neck cancer who underwent curative radiotherapy. Ten of them were evaluated for set up error. The landmarks of the ramus, chin, posterior neck, and clavicle were specified using ARIA software (Offline review), and the positional difference was analyzed. Results: The re-CT simulation therapy was performed in 60 men with $17{\pm}4$ cycles of treatment. The weight loss rate was $-6.47{\pm}3.5%$. 29 women performed re-CT simulation at $17{\pm}5$ cycles As a result, weight loss rate was $-5.73{\pm}2.7%$. The distance from skin to C1, C3, and C5 was measured, and both clavicle levels were observed to measure the skin shrinkage changes. The skin shrinkage standard deviations were C1 (${\pm}0.44cm$), C3 (${\pm}0.83cm$), and C5 (${\pm}1.35cm$), which is about 1 mm shrinkage per 0.5 kg reduction. Skin shrinkage according to the number of treatments was 1 ~ 4 fractions (no change), 5 ~ 13 fractions (-2 mm), 14 ~ 22 fractions (-4 mm) and 23 ~ 30 fractions (-6 mm). Conclusion: When the body shape changes about 5 mm, the central dose starts to differ about 3 % or more. Therefore, the CT simulation treatment for the adaptive therapy should be additionally performed. In addition, it is necessary to actively study the CT simulation therapy method and set up method of the lower neck and to examine the use of a new immobilization device.

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Study of Motion Effects in Cartesian and Spiral Parallel MRI Using Computer Simulation (컴퓨터 시뮬레이션을 이용한 직각좌표 및 나선주사 방식의 병렬 자기공명 영상에서 움직임 효과 연구)

  • Park, Sue-Kyeong;Ahn, Chang-Beom;Sim, Dong-Gyu;Park, Ho-Chong
    • Investigative Magnetic Resonance Imaging
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    • v.12 no.2
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    • pp.123-130
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    • 2008
  • Purpose : Motion effects in parallel magnetic resonance imaging (MRI) are investigated. Parallel MRI is known to be robust to motion due to its reduced acquisition time. However, if there are some involuntary motions such as heart or respiratory motions involved during the acquisition of the parallel MRI, motion artifacts would be even worse than those in conventional (non-parallel) MRI. In this paper, we defined several types of motions, and their effects in parallel MRI are investigated in comparisons with conventional MRI. Materials and Methods : In order to investigate motion effects in parallel MRI, 5 types of motions are considered. Type-1 and 2 are periodic motions with different amplitudes and periods. Type-3 and 4 are segment-based linear motions, where they are stationary during the segment. Type-5 is a uniform random motion. For the simulation, Cartesian and spiral grid based parallel and non-parallel (conventional) MRI are used. Results : Based on the motions defined, moving artifacts in the parallel and non-parallel MRI are investigated. From the simulation, non-parallel MRI shows smaller root mean square error (RMSE) values than the parallel MRI for the periodic (type-1 and 2) motions. Parallel MRI shows less motion artifacts for linear(type-3 and 4) motions where motions are reduced with shorter acquisition time. Similar motion artifacts are observed for the random motion (type-5). Conclusion : In this paper, we simulate the motion effects in parallel MRI. Parallel MRI is effective in the reduction of motion artifacts when motion is reduced by the shorter acquisition time. However, conventional MRI shows better image quality than the parallel MRI when fast periodic motions are involved.

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Influence of Fly Ash Application on Growth and Yield of Corn(Zea mays L.) (석탄회(石炭灰)(Fly Ash) 시용(施用)이 옥수수의 생육(生育) 및 수량(收量)에 미치는 영향(影響))

  • Kim, Jeong-Je;Yang, Jae-Eui;Cho, Byong-Ok;Choi, Byeong-Seon;Park, Jong-Hyun
    • Korean Journal of Soil Science and Fertilizer
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    • v.25 no.3
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    • pp.249-254
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    • 1992
  • This research was conducted to investigate the effects of fly ash applications on growth and yield parameters of corn (Zea mays L.), and soil chemical properties. Corn height at silking stage, and height and dry matter ratio at harvesting stage were enhanced by applications of fly ashes derived from bituminous coal and anthracite, respectively. Effects of fly ash treatment on growth parameters of corn were varied with kinds and levels of fly ash application and growth periods, but relatively small without revealing a major negative effect as compared to the control. Yield of corn was increased by applying fly ash of anthracite origin, but other yield components were not influenced negatively by fly ash treatment. Soil total carbon contents, cation exchange capacity, and phosphorus contents of soils sampled after harvest of corn were significantly increased by fly ash treatment, although there were slightly different effects according to kinds and levels of fly ash application. Exchangeable cations of soils were varied within an experimental error range. Phosphorus taken up by corn was enhanced by treating fly ash of the bituminous coal to the soil and there were a positive correlation between phosphorus uptake and soil Phosphorus level. Cation uptake by corn was changed a little, but no significant reduction was observed in cation uptake due to fly ash treatment. It seems to be difficult to figure out the mechanism of fly ash effects on growth and nutrient uptake by corn with one year field experiment, however treatment of fly ash enhanced some parameters of growth and yield, and nutrient uptake by corn without revealing any major negative effects. To determine the value of fly ash as a fertilizer source, continuous researches under various soil and crop conditions were considered to be necessary.

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Thin Layer Drying and Quality Characteristics of Ainsliaea acerifolia Sch. Bip. Using Far Infrared Radiation (원적외선을 이용한 단풍취의 박층 건조 및 품질 특성)

  • Ning, Xiao Feng;Li, He;Kang, Tae Hwan;Lee, Jun Soo;Lee, Jeong Hyun;Ha, Chung Su
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.6
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    • pp.884-892
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    • 2014
  • The purpose of this study was to investigate the drying characteristics and drying models of Ainsliaea acerifolia Sch. Bip. using far-infrared thin layer drying. Far-infrared thin layer drying test on Ainsliaea acerifolia Sch. Bip. was conducted at two air velocities of 0.6 and 0.8 m/sec, as well as three drying temperatures of 40, 45, and $50^{\circ}C$ respectively. The drying models were estimated using coefficient of determination and root mean square error. Drying characteristics were analyzed based on factors such as drying rate, leaf color changes, antioxidant activity, and contents of polyphenolics and flavonoids. The results revealed that increases in drying temperature and air velocity caused a reduction in drying time. The Thompson model was considered suitable for thin layer drying using far-infrared radiation for Ainsliaea accerifolia Sch. Bip. Greenness and yellowness values decreased and lightness values increased after far-infrared thin layer drying, and the color difference (${\Delta}E$) values at $40^{\circ}C$ were higher than those at $45^{\circ}C$ and $50^{\circ}C$. The antioxidant properties of Ainsliaea acerifolia Sch. Bip. decreased under all far-infrared thin layer drying conditions, and the highest polyphenolic content (37.9 mg/g), flavonoid content (22.7 mg/g), DPPH radical scavenging activity (32.5), and ABTS radical scavenging activity (31.1) were observed at a drying temperature of $40^{\circ}C$ with an air velocity of 0.8 m/sec.

Comparison between Manifest Refraction and Cycloplegic Refractin for the First-time Spectacle Wearers (최초 안경착용자의 현성굴절검사(MR)와 조절마비굴절검사(CR)의 비교)

  • Kim, Hye-Ran;Choi, Sun-Mi
    • Journal of Korean Ophthalmic Optics Society
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    • v.13 no.4
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    • pp.145-149
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    • 2008
  • Purpose: To study the difference between refractive errors obtained from manifest refraction (MR) and cycloplegic refraction (CR) in first-time spectacle wearers. To study the difference between manifest refractive errors and cycloplegic refractive errors in first-time spectacle wearers. Methods: From January 2002 to December 2002, manifest and cycloplegic refractions were carried out on the patients who visited an ophthalmology clinic for a spectacle prescription for the first-time. The patients were 509 male and 499 female patients aged between from 3 to 15 years old. Results: The cycloplegic refraction showed a less myopia and a more hyperopia compared with the non-cycloplegic refraction. The differences were more in female patients. The CR showed a less myopic and a more hyperopic refractive errors than the MR. The differences were more in female patients. The average results from a pre- and a post-cycloplegic refraction showed a reduction of -0.22D in male, and -0.20D in female for the myopic group. For the myopic group, the myopic refractive errors by MR were -0.22D in male and -0.20D in female higher than the refractive errors by CR. Hyperopic group showed an increase of +0.37D in male, and +0.56D in female. For hyperopic group the hypropic refractive errors by CR were +0.37D in male and +0.56D in female higher than the refractive errors by CR. This difference between the results of a preand a post-cycloplegic refraction was more if the patients were younger. This difference between refractive errors by MR and by CR showed the younger the more and the proportions of pseudo-myopia and or latent hyperopia were also higher with younger patents age. The amounts of with-the-rule astigmatism and the oblique astigmatism were increased for the post-cycloplegic refraction in the CR refraction. Simple astigmatism reduced, but there was no difference found in the amount of astigmatism. The prevalence of simple astigmatism reduced, but there was no difference in the amount of astigmatism. Conclusions: The difference between manifest refraction and cycloplegic refraction was more in younger group. The difference of refrative error between by MR and CR increases with ageing decrease. Pseudo-myopia and latent hyperopia was also found in the younger group. Simple astigmatism reduced after cycloplegic refraction, there was no difference found in the amount of astigmatism. The prevalence of simple astigmatism reduced, but there was no difference in the amount of astigmatism.

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