• Korean Journal of Clinical Laboratory Science
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• v.37 no.2
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• pp.65-70
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• 2005

Those specifications of the CLIA analytical tolerance limits are consistent with the performance goals in Six Sigma Quality Management. Six sigma analysis determines performance quality from bias and precision statistics. It also shows if the method meets the criteria for the six sigma performance. Performance standards calculates allowable total error from several different criteria. Six sigma means six standard deviations from the target value or mean value and about 3.4 failures per million opportunities for failure. Sigma Quality Level is an indicator of process centering and process variation total error allowable. Tolerance specification is replaced by a Total Error specification, which is a common form of a quality specification for a laboratory test. The CLIA criteria for acceptable performance in proficiency testing events are given in the form of an allowable total error, TEa. Thus there is a published list of TEa specifications for regulated analytes. In terms of TEa, Six Sigma Quality Management sets a precision goal of TEa/6 and an accuracy goal of 1.5 (TEa/6). This concept is based on the proficiency testing specification of target value +/-3s, TEa from reference intervals, biological variation, and peer group median mean surveys. We have found rules to calculate as a fraction of a reference interval and peer group median mean surveys. We studied to develop total error allowable from peer group survey results and CLIA 88 rules in US on 19 items TP, ALB, T.B, ALP, AST, ALT, CL, LD, K, Na, CRE, BUN, T.C, GLU, GGT, CA, phosphorus, UA, TG tests in chematology were follows. Sigma level versus TEa from peer group median mean CV of each item by group mean were assessed by process performance, fitting within six sigma tolerance limits were TP ($6.1{\delta}$/9.3%), ALB ($6.9{\delta}$/11.3%), T.B ($3.4{\delta}$/25.6%), ALP ($6.8{\delta}$/31.5%), AST ($4.5{\delta}$/16.8%), ALT ($1.6{\delta}$/19.3%), CL ($4.6{\delta}$/8.4%), LD ($11.5{\delta}$/20.07%), K ($2.5{\delta}$/0.39mmol/L), Na ($3.6{\delta}$/6.87mmol/L), CRE ($9.9{\delta}$/21.8%), BUN ($4.3{\delta}$/13.3%), UA ($5.9{\delta}$/11.5%), T.C ($2.2{\delta}$/10.7%), GLU ($4.8{\delta}$/10.2%), GGT ($7.5{\delta}$/27.3%), CA ($5.5{\delta}$/0.87mmol/L), IP ($8.5{\delta}$/13.17%), TG ($9.6{\delta}$/17.7%). Peer group survey median CV in Korean External Assessment greater than CLIA criteria were CL (8.45%/5%), BUN (13.3%/9%), CRE (21.8%/15%), T.B (25.6%/20%), and Na (6.87mmol/L/4mmol/L). Peer group survey median CV less than it were as TP (9.3%/10%), AST (16.8%/20%), ALT (19.3%/20%), K (0.39mmol/L/0.5mmol/L), UA (11.5%/17%), Ca (0.87mg/dL1mg/L), TG (17.7%/25%). TEa in 17 items were same one in 14 items with 82.35%. We found out the truth on increasing sigma level due to increased total error allowable, and were sure that the goal of setting total error allowable would affect the evaluation of sigma metrics in the process, if sustaining the same process.

• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.1
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• pp.27-40
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• 2013

This study is about development of technology system for an advanced deep-sea unmanned underwater robot of S. Korea analysed by the application of scenario planning. It was developed a 6000m class next-generation deep-sea unmanned underwater vehicle(or robot, UUV) system, soonly ROV 'Hemire' and Depressor 'Henuvy' in 2006 at S. Korea and motion control, adaptive control algolithm, a work-space manipulator control algolithm, especially the underwater inertial-acoustic navigation system robust to initial errors and sensor failures. But there are remained matters on position tracking of the USBL, inertial-acoustic navigation system, attitude sensor, designed sonar sensors. So this study suggest the new idea for settle the matters and then this idea help the development of the underwater inertial-acoustic navigation system robust to initial errors and sensor failures, such as acoustic signal drop-out, by modifying the error covariance of the failed sonar signal when drop-out occurs. As a result, the future policy for deep-sea unmanned underwater robot of S. Korea is to further spur the development of new technology and more improvement of the technology level for deep-sea unmanned underwater robot system with indicator and imaginary wall as external device.

• Tuberculosis and Respiratory Diseases
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• v.78 no.4
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• pp.315-320
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• 2015

Background: The efficacy of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy can be measured based on the rate of treatment response, based on the Response Evaluation Criteria in Solid Tumors (RECIST) criteria or progression-free survival (PFS). However, there are some patients harboring sensitive EGFR mutations who responded poorly to EGFR-TKI therapy. In addition, there is variability in the PFS after EGFR-TKI treatment. Methods: We performed a retrospective analysis of the medical records of 85 patients with non-small cell lung cancer, who had achieved a stable disease or better response at the first evaluation of treatment response, after receiving a 2-month course of gefitinib. We calculated the tumor shrinkage rate (TSR) by measuring the longest and perpendicular diameter of the main mass on computed tomography before, and 2 months after, gefitinib therapy. Results: There was a significant positive correlation between the TSR and PFS (R=0.373, p=0.010). In addition, a simple linear regression analysis showed that the TSR might be an indicator for the PFS ($B{\pm}standard$ error, $244.54{\pm}66.79$; p=0.001). On univariate analysis, the sex, histologic type, smoking history and the number of prior chemotherapy regimens, were significant prognostic factors. On multivariate regression analysis, both the TSR (${\beta}$=0.257, p=0.029) and adenocarcinoma (${\beta}$=0.323, p=0.005) were independent prognostic factors for PFS. Conclusion: Our results showed that the TSR might be an early prognostic indicator for PFS in patients receiving EGFRTKI therapy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.7
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• pp.4528-4535
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• 2014

In this paper, a distributed evacuation system based on the positioning information of subway passengers is proposed. Recently, the subway station is becoming complicated by combining with shopping malls, and movie theaters. Compared to the increasing complexity of subway stations, evacuation systems are less complex. Subway passengers in each cell were estimated to use the access point in the subway cells and statistics information. The evacuation route is provided through a direction indicator and push alarm of a smart phone based on estimated the number of passengers and exit information of the subway station. Based on this schemes, a quick and safe evacuation system of subway passengers was proposed. The number of connection passengers was estimated using AP with OpenWrt embedded OS installed. The average error rate of the number of passenger was confirmed to be 15%, 17% and 23% at the confidence parameter of $1{\sigma}$, $2{\sigma}$, and $3{\sigma}$, respectively, through a simulation. The possibility of the system through a simple experiment was examined.

• Journal of the Korea Convergence Society
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• v.8 no.1
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• pp.19-23
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• 2017

Energy is a vital resource for the economic growth and the social development for any country. As the industry becomes more sophisticated and the economy more grows, the electricity demand is increasing. So forecasting electricity demand is an important for electricity suppliers. Forecasting electricity demand makes it possible to distribute electricity demand. As the market for Negawatt market began to grow in Korea from 2014, the prediction of electricity consumption demand becomes more important. Moreover, power consumption forecasting provides a way for demand management to be directly or indirectly participated by consumers in the electricity market. We use Genetic Algorithms to predict the energy demand of the fishing industry in Jeju Island by using GDP, per capita gross national income, value add, and domestic electricity consumption from 1999 to 2011. Genetic Algorithm is useful for finding optimal solutions in various fields. In this paper, genetic algorithm finds optimal parameters. The objective is to find the optimal value of the coefficients used to predict the electricity demand and to minimize the error rate between the predicted value and the actual power consumption values.

• Journal of Advanced Navigation Technology
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• v.19 no.6
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• pp.558-563
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• 2015

There have recently been various services that use indoor location estimation technologies. Representative methods of location estimation include fingerprinting and triangulation, but they lack accuracy. Various kinds of research which apply existing location estimation methods like AOA, TOA, and TDOA are being done to solve this problem. In this paper, we study the location estimation algorithm based on AOA using a RSSI difference in indoor environments. We assume that there is a single AP with four antennas, and estimate the angle of arrival based on the RSSI value to apply the AOA algorithm. To compensate for RSSI, we use a recursive averaging filter, and use the corrected RSSI and the Pythagorean theorem to estimate the angle of arrival. The results of the experiment, show an error of 18% because of the radiation pattern of the four non-directional antennas arranged at narrow intervals.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.9
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• pp.878-885
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• 2009

One of important factors in designing MEMS resonators for RF filters is obtaining a desired frequency response function (FRF) within a specific frequency range of interest. Because various array-type MEMS resonators have been recently introduced to improve the filter characteristics such as bandwidth, pass-band, and shape factor, the degrees of freedom (DOF) of finite elements for their FRF calculation dramatically increases and therefore raises computational difficulties. In this paper the Krylov subspace-based model order reduction using moment-matching with non-zero expansion points is represented as a numerical solution to perform the frequency response analyses of those array-type MEMS resonators in an efficient way. By matching moments at a frequency around the specific operation range of the array-type resonators, the required FRF can be efficiently calculated regardless of their operating frequency from significantly reduced systems. In addition, because of the characteristics of the moment-matching method, a minimal order of reduced system with a prearranged accuracy can be determined through an error indicator using successive reduced models, which is very useful to automate the order reduction process and FRF calculation for structural optimization iterations. We also found out that the presented method could obtain the FRF of a $6\times6$ array-type resonator within a seventieth of the computational time necessary for the direct method and in addition FRF calculation by the mode superposition method could not even be completed because of a data overflow with a half after calculation of 9,722 eigenmodes.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.9
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• pp.933-941
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• 2014

This paper provides a comparison between the Krylov subspace method (KSM) and modal truncation method (MTM), which are typical projection-based model order reduction methods. The frequency responses are compared to determine the numerical accuracies and efficiencies. In order to compare the numerical accuracies of the KSM and MTM, the frequency responses and relative errors according to the order of the reduced model and frequency of interest are studied. Subsequently, a numerical examination shows whether a reduced order can be determined automatically with the help of an error convergence indicator. As for the numerical efficiency, the computation time needed to generate the projection matrix and the solution time to perform a frequency response analysis are compared according to the reduced order. A finite element model for a car suspension is considered as an application example of the numerical comparison.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.17 no.2
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• pp.129-136
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• 1999

The quality of image classification results is not always uniform over entire image. Thus, this study proposes the concept of ISDd (Index of Spatial Distribution by distance) and ISDs (ISD by scatteredness) for the evaluation of unevenness of result quality, and spatial distribution of satellite image classification errors. The ISDd is indexed mean distance of misclassified pixels and the ISDs is statistical indicator of scatteredness of misclassified pixels. In this study, the ISDd and the ISDs are calculated and evaluated for some satellite images, then misclassified area is extracted and the reasons of misclassification are examined. As the result of this study, using both the ISDd and the ISDs, the basis of decision on adoption/rejection of classification results is offered at sub-image level by evaluation of the local aggregation of misclassified pixels. Using Index of Spatial Distribution. as well as overall classification accuracy, users can understand the spatial distribution of misclassified pixels, and can have the additional criterion of the judgement on suitability and reliability of classification results.

• Journal of Korean Tunnelling and Underground Space Association
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• v.18 no.3
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• pp.331-339
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• 2016

Real time location (RTL) system which can control the safety of laborers in the underground space is developed in this study. This innovative system can monitor the location and history of movement of multiple laborers in real time. To accommodate constrains of the underground space, the system is portable and composed with low-battery mode. Since conventional method to detect the location of laborer with radio signal strength indicator (RSSI) contains high errors, new measurement system using accelerometers and correction method are suggested in this study. Field test is performed to validate the developed system. The error for moving laborer was 0.4 m and for non-moving laborers was 0.2 m. Thus, it is found that the new RTL system can be used to monitor the location of laborers in the underground construction space.