• 제목/요약/키워드: Epileptic seizure

검색결과 127건 처리시간 0.033초

간질발작(癎疾發作)환자 치험 1예 (A Case Report of patient with epileptic seizure)

  • 이정은;황지호;임도희;한영주;배한호;정인철;박양춘
    • 대한한방내과학회지
    • /
    • 제26권2호
    • /
    • pp.453-458
    • /
    • 2005
  • Epilepsy is a neurological condition that from time to time produces brief disturbances in the normal electrical functions of the brain, Normal brain function is made possible by millions of tiny electrical charges passing between nerve cells in the brain and to all parts of the body. They may affect a person's consciousness, bodily movements or sensations for a short time. These physical changes are called epileptic seizures. These clinical data, gathered an epileptic seizure whose main symptom was convulsion, was analyzed. This clinical report pertains to a 51 year-old man who suffered an epileptic seizure and after effects of weakness. He was treated with ChongsimOndamTang(淸心溫膽湯). The cheif symptom, epileptic seizure, disappeared and general conditions improved after Korean medical treatments, so this is reported as a potential treatment.

  • PDF

지속적 간질 이후에 발생한 일측대뇌반구위축증 (Cerebral hemitrophy)이 의심되는 환아(患兒) 1례(例)에 대한 증례보고(症例報告) (A Case of Cerebral Hemiatrophy Developed after Continued Epileptic Seizure)

  • 조형준;신동길;이진용;김덕곤
    • 대한한방소아과학회지
    • /
    • 제16권1호
    • /
    • pp.75-80
    • /
    • 2002
  • A 10-year-old boy with a history of epileptic seizure for 3 years, showed ataxia and left side weakness. In Brain MRI, hemiatrophy of the right hemisphere was noted. So we considered that he had a cerebral hemiatrophy caused by continued epileptic seizure and treated him with herbal medicine, acupuncture and physical therapy. We report a case of a 10-year-old boy who showed symptoms of a cerebral hemiatrophy caused by maintained epileptic seizure.

  • PDF

간질 발작 환자의 화상 (Burns in Patients with Epileptic Seizure)

  • 박영규;이종욱;오석준;장영철
    • Archives of Plastic Surgery
    • /
    • 제32권2호
    • /
    • pp.250-254
    • /
    • 2005
  • Burns due to epileptic seizures are commonly deep and usually require operative treatment. The purpose of this study is to identify the characteristics of burned epileptic patients that could lead to the development of preventive programs to reduce the incidence of burn injuries. We analyzed epidemiological data for 34 patients acutely burned due to epileptic seizure admitted retrospectively. There were 15 male and 19 female subjects. The age distribution was from 6 years to 70 years with the mean age of 42.7 years. Seizures usually occurred while carrying out daily domestic chores. Scalding burns were the most common(38.2%) and most burns were above deep second degree(94.1%). The most common seizure type was generalized tonic-clonic, followed by absence and complex partial. The seizure mostly occurred in the morning because the therapeutic blood level of antiepileptic drugs was decreased extremely at that time by stopping drug arbitrarily or taking inadequately. So more frequent follow-ups at the neurology outpatient clinics for epileptics should be strictly reinforced to maintain the adequate therapeutic blood levels of antiepileptic drugs and fire protective implements should be prepared in the house.

난치성 간질환자에서 간질관련요인이 발작간 정신증상에 미치는 영향 (The Effect of Seizure-Related Variables on Interictal Psychiatric Symptoms in the Intractable Epileptic Patients)

  • 김종훈;한우상;이상건;류인균;하규섭
    • 정신신체의학
    • /
    • 제5권2호
    • /
    • pp.205-213
    • /
    • 1997
  • The aim of this study is to find the relationship between interictal psychiatric symptoms and seizure-related variables such as structural changes, regional interictal perfusion changes, the number of interictal epileptic discharges and the presence of accompanying generalized tonic clonic seizure(GTC). The subjects were 75 patients (47 males : mean age $28.3{\pm}7.7$) with intractable epilepsy, Interictal psychiatric symptoms were rated by Symptom Checklist-90-R(SCL-90-R). Each of 4 seizure variables was measured by MRI, $^{99m}TC-HMPAO$ SPECT and the prolonged EEG monitoring. The mean SCL-90-R subscale T-scores and the ratio of the patients with definite psychiatric symptoms(T-score > 65 at any one subscale of SCL-90-R) were compared among the groups with different seizure variables. Demographic variables and clinical variables were not statistically different among the groups with different seizure variables. The patients with right mesial temporal sclerosis had higher mean SCL-90-R scores for obsessive compulsive symptom, interpersonal sensitivity, depression, hostility and psychotic symptoms than the patients with left mesial temporal sclerosis, and they also showed higher ratio of definite psychiatric symptoms. The presence of interictal epileptic discharges was related with higher T-scores of paranoid subscale. The areas of hypoperfusion, the presence of the GTC, and other clinical seizure variables showed no significant influences on the mean SCL-90-R subscale T-scores. from these results, the authors speculated that interictal subictal epileptic dischrages may be related with psychiatric symptoms of the intractable epileptic patients, especially with right mesial temporal sclerosis.

  • PDF

삼출건비탕가미방(蔘出健脾湯加味方)을 이용한 식간(食癎) 환아 치험 2례에 대한 증례보고 (A Case Report Regarding a Treatment Includes Lots of Different Version of Samchulkunbi-tang (蔘朮健脾湯) to Two Pediatric Patients Diagnosed as Sik-gan (食癎))

  • 김은진;민상연;김장현
    • 대한한방소아과학회지
    • /
    • 제27권4호
    • /
    • pp.1-9
    • /
    • 2013
  • Objectives The purpose of this study is to report the cases of two pediatric patients diagnosed as Sik-gan (食癎), a kind of epileptic seizure thought to be caused by uncontrolled consumption of food, treated by formula variation of Samchulkunbi-tang (蔘朮健脾湯). Methods Two pediatric patients diagnosed as Sik-gan (食癎) according to traditional Korean medical terms were administered by variety of Samchulkunbi-tangs (蔘朮健脾湯) while correcting unhealthy eating habit. To measure the degree of the patients' process, the number and exact symptoms of seizure events, and gastrointestinal symptoms were recorded. Results The treatment of various Samchulkunbi-tang (蔘朮健脾湯) was not only extended remission period of seizure, but also improved gastrointestinal symptoms on both of the patients. Conclusions Pediatric patients who have past medical conditions for epileptic seizure as well as unhealthy eating habits or gastrointestinal malfunctions are prone to have a specific form of seizure called the Sik-gan (食癎). In this report, we have proven that variety of Samchulkunbi-tang (蔘朮健脾湯) can considerably be effective in improving the patients' gastrointestinal symptoms and preventing recurring seizure events.

전신 근간대성 경련을 호소하는 정신성 비간질성 경련 환자에 대한 억간산 및 황련해독탕 병용 투여 치험 1례 (A Case of Psychogenic Non-epileptic Seizure Patient Complaining Myoclonic Seizure Treated with Ukgansan and Hwangnyeonhaedok-tang)

  • 배인후;하원정;서유나;이현규;김수현;조기호;문상관;정우상;권승원;진철
    • 대한중풍순환신경학회지
    • /
    • 제21권1호
    • /
    • pp.33-38
    • /
    • 2020
  • ■ Objectives This case report is reported to show the effect of Ukgansan and Hwangnyeonhaedok-tang on a patient who complaining myoclonic seizure due to psychogenic non epileptic seizure, occurred after traumatic stress event. ■ Methods A female patients with myolconic seizure was treated with Ukgansan and Hwangnyeonhaedok-tang during 5 days. Then we assessed dyskinesia severity by AIMS(Abnormal Involuntary Movement Scale) every two days til discharge. ■ Results Seizure decreased two days after hospitalization, then disappeared third day. There was no recurrence till discharge. When she revisited outpatients clinic, there was no symptom. ■ Conclusion This case showed the effect of Ukgansan and Hwangnyeonhaedok-tang on psychogenic epileptic seizure.

  • PDF

L1-norm Minimization based Sparse Approximation Method of EEG for Epileptic Seizure Detection

  • Shin, Younghak;Seong, Jin-Taek
    • 한국정보전자통신기술학회논문지
    • /
    • 제12권5호
    • /
    • pp.521-528
    • /
    • 2019
  • Epilepsy is one of the most prevalent neurological diseases. Electroencephalogram (EEG) signals are widely used for monitoring and diagnosis tool for epileptic seizure. Typically, a huge amount of EEG signals is needed, where they are visually examined by experienced clinicians. In this study, we propose a simple automatic seizure detection framework using intracranial EEG signals. We suggest a sparse approximation based classification (SAC) scheme by solving overdetermined system. L1-norm minimization algorithms are utilized for efficient sparse signal recovery. For evaluation of the proposed scheme, the public EEG dataset obtained by five healthy subjects and five epileptic patients is utilized. The results show that the proposed fast L1-norm minimization based SAC methods achieve the 99.5% classification accuracy which is 1% improved result than the conventional L2 norm based method with negligibly increased execution time (42msec).

The earth mover's distance and Bayesian linear discriminant analysis for epileptic seizure detection in scalp EEG

  • Yuan, Shasha;Liu, Jinxing;Shang, Junliang;Kong, Xiangzhen;Yuan, Qi;Ma, Zhen
    • Biomedical Engineering Letters
    • /
    • 제8권4호
    • /
    • pp.373-382
    • /
    • 2018
  • Since epileptic seizure is unpredictable and paroxysmal, an automatic system for seizure detecting could be of great significance and assistance to patients and medical staff. In this paper, a novel method is proposed for multichannel patient-specific seizure detection applying the earth mover's distance (EMD) in scalp EEG. Firstly, the wavelet decomposition is executed to the original EEGs with five scales, the scale 3, 4 and 5 are selected and transformed into histograms and afterwards the distances between histograms in pairs are computed applying the earth mover's distance as effective features. Then, the EMD features are sent to the classifier based on the Bayesian linear discriminant analysis (BLDA) for classification, and an efficient postprocessing procedure is applied to improve the detection system precision, finally. To evaluate the performance of the proposed method, the CHB-MIT scalp EEG database with 958 h EEG recordings from 23 epileptic patients is used and a relatively satisfactory detection rate is achieved with the average sensitivity of 95.65% and false detection rate of 0.68/h. The good performance of this algorithm indicates the potential application for seizure monitoring in clinical practice.

Kainic acid로 유도된 생쥐의 간질 발작에 대한 천마 메탄올 추출물의 항경련 효과 연구 (Anti-convulsant Effects of Methanol Extract of Gastrodia Elata on Kainic Acid-induced Epilepsy Mouse Model)

  • 장정희;배창환;김형우;김승태
    • 동의생리병리학회지
    • /
    • 제28권6호
    • /
    • pp.614-620
    • /
    • 2014
  • Kainic acid (KA) is a excitatory agonist causing epileptic seizure and excitotoxicity in the hippocampus. Gastrodia Elata (GE) is known to have anti-convulsant and anti-oxidant effects. This study was investigated a possible role of GE in suppressing epileptic seizure using KA-induced epilepsy mouse model. Eight-week-old male C57BL/6 mice were administrated GE (50 or 500 mg/kg) once a day for 5 days, and then injected KA (30 mg/kg) intraperitoneally. Behavioral changes in mice by KA were evaluated for 90 minutes immediately after the KA administration. Six hours after the KA administration, their brains were harvested and the expressions of glutamate decarboxylase 67 (GAD-67) and K+-Cl- cotransporter 2 (KCC2) in the hippocampus of the mice were measured by immunohistochemistry.GE delayed the onset of epileptic seizure after KA administration, suppressed the severity of the seizure and decreased the number of severe seizures dose dependently. Moreover, GAD-67 and KCC2 expressions in the cornu ammonis (CA) 1 and CA3 of 500 mg/kg GE administrated mice were significantly increased compared to those in KA-treated mice.GAD-67 and KCC2 play an important role in regulating GABAergic system. Our results suggest that GE has anti-convulsant effect against KA-induced epileptic seizure through enhancing GABAergic system.

간질 동물 모델을 이용한 곡지(曲池) 및 족삼리(足三里)의 간질발작 및 해마 신경세포 보호 효과 비교 연구 (Acupuncture Stimulation at LI11 Suppresses Seizure and Apoptosis in Hippocampi on an Epilepsy Mouse Model)

  • 이종분;황경민;유태원;배창환;권선오;김승태
    • Korean Journal of Acupuncture
    • /
    • 제30권1호
    • /
    • pp.73-80
    • /
    • 2013
  • Objectives : LI11 has been known to suppress epileptic seizure. Using an mouse epilepsy model, we investigated whether acupuncture stimulation at LI11 can suppress kainic acid(KA)-induced epileptic seizure and apoptosis in the mouse hippocampus. Methods : Eight-week-old male C57/BL6 mice(20~25 g) were given acupuncture at LI11 or ST36 once a day for 3 days. After the last acupuncture stimulations, KA(30 mg/kg) was injected intraperitoneally and the degree of seizure was observed for 90 minutes. Twenty-four hours after KA administration, mice were sacrificed and the neural cell death, astrocyte activation and caspase-3 expression in their hippocampi were investigated. Results : Acupuncture stimulation at LI11 suppressed KA-induced epileptic seizure, neuronal cell death, astrocyte activation and caspase-3 expression. Conclusions : Acupuncture stimulation at LI11 decreases the KA-induced epileptic seizure and protects hippocampal cell death via regulating astrocyte activation and caspase-3 expression.