• Title/Summary/Keyword: Epidemiologic methods

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No Effect of Energy Intake Overall on Risk of Endometrial Cancers: a Meta-analysis

  • Chu, Ke-Tan;Song, Yang;Zhou, Jian-Hong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10293-10298
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    • 2015
  • Background: Previous epidemiologic studies on the association between energy intake and endometrial cancer risk have only generated contradictory results. The role of energy intake in endometrial carcinogenesis thus remains unclear. To quantitatively assess the potential association between energy intake and endometrial cancer, a meta-analysis of case-control and cohort studies was here conducted. Materials and Methods: Eligible studies were retrieved via both computerized searches and review of references. Fixed-or random-effect models were used to summarize the estimates of OR with 95%CIs. Stratified analyses on study design, region and macronutrients' calorie were performed. Results: Sixteen studies met the inclusion criteria of the meta-analysis. No association between total energy intake and endometrial cancer was observed in either overall group (OR=1.11, 95%CI 0.92-1.30) or subgroups stratified by study design and region. In the specific macronutrients' calorie analysis, higher fat energy intake was found to be associated with increased endometrial risk (OR=1.72, 95%CI 1.12-2.32) while energy from carbohydrate and protein was not related to endometrial cancer risk. Conclusions: Our analysis did not support that total energy intake is related to endometrial cancer risk, in contrast to fat energy.

An Experience of Management of Homeless Neurosurgical Patients

  • Kim, Dae-Ki;Jwa, Cheol-Su;Kim, Gang-Hyeon;Kang, Jae-Kyu
    • Journal of Korean Neurosurgical Society
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    • v.42 no.3
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    • pp.191-194
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    • 2007
  • Objective : Homeless patients probably have epidemiologic features that are different from those of general population. However, there have been no published articles about clinical characteristics of neurosurgical homeless patients. The authors tried to assess the clinical characteristics and treatment outcome of homeless neurosurgical patients. Methods : We retrospectively reviewed the medical records and radiological films of 76 homeless patients and 72 non-homeless patients following head trauma who were admitted to our neurosurgical department between June 2001 and June 2005. We compared two groups of the patients with the demographics, the clinical and laboratory characteristics. Also, 3D-day mortality was determined according to Glasgow Coma Scale (GCS) score. Results : Age of homeless patients was younger than that of non-homeless patients. Homeless patients had previous craniotomy evidences in skull x-rays more frequently (10.5% vs. 1.4%). Acute subdural hematoma was the most common type of head injury in the two groups. Moderate and severe head injury, based on GCS score on admission was more frequent in homeless patients (64% vs. 39%). Fifty percent of homeless patients underwent operation for traumatic head injury. However, 3D-day mortality according to GCS score was not significantly higher in homeless patients. Conclusion : Most homeless neurological patients were relatively young men. Also, moderate or severe brain injuries were observed more frequently. However, mortality rate of homeless patients in neurosurgical field is not significantly higher in the present study.

Association between phytochemical index and metabolic syndrome

  • Kim, Minkyeong;Park, Kyong
    • Nutrition Research and Practice
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    • v.14 no.3
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    • pp.252-261
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    • 2020
  • BACKGROUND/OBJECTIVES: Although previous experimental studies reported the health benefits of foods rich in phytochemicals, few epidemiologic studies have investigated the associations between phytochemicals and metabolic disorders. This study aimed to calculate a phytochemical index (PI) and examine its association with metabolic syndrome in the Korean population. SUBJECTS/METHODS: Data of Korean adults aged ≥ 19 years who participated in the 2008-2016 Korea National Health and Nutrition Examination Surveys were analyzed. The PI was calculated using 24-hour intake recall data regarding whole grains, vegetables, fruits, legumes, nuts and seeds, and soybeans and soy products. Demographic and lifestyle data were obtained using self-administered questionnaires. A multivariable logistic regression was performed to calculate the adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the prevalence of metabolic syndrome and its components according to PI quintiles. RESULTS: Overall, 31,319 adults were evaluated. Compared with men, women had a higher median PI level (9.96 vs. 13.63) and significantly higher caloric intake levels from most PI components (P < 0.05), except for soy products. After adjusting for multiple confounding variables, participants in the highest PI quintile had significantly lower prevalences of abdominal obesity (OR: 0.90, 95% CI: 0.81-0.99), hyperglycemia (OR: 0.83, 95% CI: 0.74-0.94), high blood pressure (OR: 0.82, 95% CI: 0.73-0.93), hypertriglyceridemia (OR: 0.84, 95% CI: 0.75-0.94), and metabolic syndrome (OR: 0.78, 95% CI: 0.69-0.88). CONCLUSIONS: Higher intakes of phytochemical-rich foods are associated with a lower prevalence of metabolic dysregulation and consequently, cardiometabolic diseases.

Factors Influencing Illness Intrusiveness of the Sexual Life in Women with Overactive Bladder (과민성방광 여성 환자의 성생활에 관한 지각된 질병의거변화의 영향요인)

  • Cho, Jeong Lim;Lee, Eun Nam
    • Journal of muscle and joint health
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    • v.20 no.1
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    • pp.62-71
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    • 2013
  • Purpose: This study was conducted to explore factors that influence illness intrusiveness of the sexual life in women with overactive bladder. Methods: Ninety-two women diagnosed with overactive bladder, from D University Hospital and three private urology hospitals in B region, participated in a survey between April 7 and August 7, 2012. The Overactive Bladder-questionnaire (OAB-q), the Marital Intimacy Tool, the Center for Epidemiologic Studies Depression (CES-D), and 1 question to ask illness intrusiveness of the sexual life were used in the study. Results: The illness intrusiveness score of the sexual life in women with overactive bladder was 2.22 out of 5. There were no significant differences of illness intrusiveness by demographic and disease related characteristics. The predictor were the clinical symptom score and depression, accounting for 13% of the variance of the illness intrusiveness of the sexual life in the women with overactive bladder. Conclusion: Effective nursing intervention to relieve clinical signs of overactive bladder and reduce depression can improve quality of sexual life in women with overactive bladder.

Hormone Replacement Therapy and Risk of Breast Cancer in Korean Women: A Quantitative Systematic Review

  • Bae, Jong-Myon;Kim, Eun Hee
    • Journal of Preventive Medicine and Public Health
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    • v.48 no.5
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    • pp.225-230
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    • 2015
  • Objectives: The epidemiological characteristics of breast cancer incidence by age group in Korean women are unique. This systematic review aimed to investigate the association between hormone replacement therapy (HRT) and breast cancer risk in Korean women. Methods: We searched electronic databases such as KoreaMed, KMbase, KISS, and RISS4U as well as PubMed for publications on Korean breast cancer patients. We also conducted manual searching based on references and citations in potential papers. All of the analytically epidemiologic studies that obtained individual data on HRT exposure and breast cancer occurrence in Korean women were selected. We restricted the inclusion of case-control studies to those that included age-matched controls. Estimates of summary odds ratio (SOR) with 95% confidence intervals (CIs) were calculated using random effect models. Results: One cohort and five case-control studies were finally selected. Based on the heterogeneity that existed among the six studies (I-squared=70.2%), a random effect model was applied. The summary effect size of HRT history from the six articles indicated no statistical significance in breast cancer risk (SOR, 0.983; 95% CI, 0.620 to 1.556). Conclusions: These facts support no significant effect of HRT history in the risk of breast cancer in Korean women. It is necessary to conduct a pooled analysis.

Effect of aquatic exercise on balance and depression of stroke patients (수중운동이 뇌졸중 환자의 균형과 우울에 미치는 효과)

  • Kim, Se-Hun;Lee, Dong-Kyu;Kim, Eun-Kyung
    • The Journal of Korean Physical Therapy
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    • v.26 no.2
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    • pp.104-109
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    • 2014
  • Purpose: The purpose of this study was to understand the effect of aquatic exercise on balance and depression of stroke patients. Methods: For 12 participants with stroke, six members of the experimental group and six members of the control group were randomly selected and arranged. Proprioceptive Neuromuscular Facilitation (PNF) lower extremity aquatic pattern exercise was applied to the experimental group. On the other hand, participants in the control group performed PNF lower extremity pattern exercise on the ground. Both exercises were performed 30 minutes per day, five times per week, for a period of six weeks. Balance was assessed using the Berg Balance Scale (BBS) and Timed Up to Go test (TUG). Depression was measured using the Center for Epidemiologic Studies depression scale (CES-D). Results: As a result of comparison within groups, the experimental group showed significant difference for balance and depression after the experiment (p<0.05). In comparison between the two groups, the experimental group in which aquatic exercise was applied showed more significant change in balance and depression than the control group (p<0.05). Conclusion: According to the results of this study, aquatic exercise was proven to enhance the balance and decrease the depression of stroke patients.

Cancer Mortality and Incidence in Cement Industry Workers in Korea

  • Koh, Dong-Hee;Kim, Tae-Woo;Jang, Seung-Hee;Ryu, Hyang-Woo
    • Safety and Health at Work
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    • v.2 no.3
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    • pp.243-249
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    • 2011
  • Objectives: Cement contains hexavalent chromium, which is a human carcinogen. However, its effect on cancer seems inconclusive in epidemiologic studies. The aim of this retrospective cohort study was to elucidate the association between dust exposure in the cement industry and cancer occurrence. Methods: The cohorts consisted of male workers in 6 Portland cement factories in Korea. Study subjects were classified into five groups by job: quarry, production, maintenance, laboratory, and office work. Cancer mortality and incidence in workers were observed from 1992 to 2007 and 1997-2005, respectively. Standardized mortality ratios and standardized incidence ratios were calculated according to the five job classifications. Results: There was an increased standardized incidence ratio for stomach cancer of 1.56 (27/17.36, 95% confidence interval: 1.02-2.26) in production workers. The standardized mortality ratio for lung cancer increased in production workers. However, was not statistically significant. Conclusion: Our result suggests a potential association between cement exposure and stomach cancer. Hexavalent chromium contained in cement might be a causative carcinogen.

Epidemiological Investigation of an Outbreak of Salmonellosis in Gyeongju, Korea

  • Yoo, Seok-Ju;Lim, Hyun-Sul;Lee, Kwan
    • Journal of Preventive Medicine and Public Health
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    • v.47 no.3
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    • pp.177-181
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    • 2014
  • Objectives: A salmonellosis outbreak occurred within a community of Gyeongju residents who ingested catered food from a wedding in June 2009. We aimed to epidemiologically investigate the probable vehicle of the infection. Methods: We conducted a retrospective cohort study on 34 local residents who ingested the wedding food. Results: Among the 34 residents, 31 (91.2%) reported symptoms of infection after eating the food. Among all of the wedding foods, pan-fried foods were highly associated with the diarrheal attack rate. On bacteriological examination, Salmonella species were detected in the pan-fried foods among the leftover foods and in 17 of the 31 stool specimens from the cases. There were five different types of pan-fried foods, but the onset of symptoms was independent of the ingredients used. We found that the pan-fried food was prepared at a food store in Seoul and that eggs were a common ingredient. Conclusions: The major cause of the salmonellosis in this population was presumed to be the pan-fried food prepared with contaminated eggs. These food items might have been partially undercooked because of their irregular shape, which allowed the Salmonella species to survive and multiply before ingestion.

Relationships of Depression Symptom, Self-Esteem, and Stress to Health-Related Quality of Life in Patients with Hypertension Registered to a Community Health Center (보건소를 이용하는 고혈압 환자의 우울증상, 자아존중감, 스트레스 및 건강관련 삶의 질 관계)

  • Choi, Mi Ni;Lee, Eun-Hyun
    • Journal of Korean Public Health Nursing
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    • v.29 no.2
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    • pp.165-176
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    • 2015
  • Purpose: This study was conducted to examine the relationships of depression symptom, self-esteem, and stress with health-related quality of life(HRQOL) in patients with hypertension registered to a community health center. Methods: This study was a correlational survey using a convenience sampling. A total of 110 patients diagnosed with hypertension were recruited from a health center in Gyeonggi-do. The questionnaires used were the Cardiovascular Disease Specific-HRQOL questionnaire, Center for Epidemiologic Studies Depression, Rosenberg Self-Esteem Scale, and Perceived Stress Scale. The acquired data were analyzed using IBM SPSS version 22.0. Multiple linear regression analysis was performed. Results: Moderate depression symptom(${\beta}=-.368$, p<.001), severe depression symptom (${\beta}=-.450$, p<.001), stress(${\beta}=-.339$, p=.001), and gender(${\beta}=-.148$, p=.049) were significant predictors for the HRQOL. Multiple linear regression showed that 51.8% ($R^2=.518$) of the variance in the HRQOL was explained. Conclusion: Based on these results, development of an intervention or education program, to decrease depression symptoms and stress is recommended. This may improve the HRQOL in patients with hypertension registered to a community health center.

The Validity and Reliability of a Lifestyle Evaluation Tool for Patients with Metabolic Syndrome (대사증후군 대상자의 생활습관 평가 도구 개발을 위한 타당도와 신뢰도 검증)

  • Kang, Se-Won
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.17 no.4
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    • pp.487-497
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    • 2010
  • Purpose: This study examined the validity and reliability to develop a lifestyle evaluation tool for metabolic syndrome patients. Methods: A methodological research design was used. The construct factors and preliminary items were identified by reviewing previous researches and tools related to lifestyle and reviewed by ten experts. It was tested with 195 patients with metabolic syndrome in a university hospital. The data were analyzed with SPSS/WIN 14.0. Results: To test the validity, principal component analyses were used and resulted in the extraction of six components. The convergent validity resulted r= .72 (p<.001) with Health Promotion Lifestyle Profile. The discriminant validity with Center for Epidemiologic Studies Depression Scale resulted r= -.15 (p=.004). The Internal consistency of the tool had an Cronbach's a of .92. The self-report format Lifestyle Evaluation Tool for the patients with metabolic syndrome was developed with 36 items and four-rating scales:'physical activity and weight control' eight items, 'dietary habits' sixteen items, 'drinking and smoking' three items, 'sleep and rest' two items, 'stress' three items, 'drug and health management' four items. Conclusion: This Tool will evaluate health behaviors in patients with metabolic syndrome. Also, it will contribute to the development of nursing intervention to improve the metabolic syndrome patients' lifestyle.