• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 1999년도 Proceedings of International Symposium on Remote Sensing
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• pp.443-449
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• 1999

The investigation of the amount of the ecosystem damage on the shoreline due to the NAHODKA oil-spill accident, which occurred in the Sea of Japan, was attempted by using geoinformatics. At first, it was assumed that symbolical vegetation's distribution could be specified in the coast in Ishikawa Pref. where the heavy oil was washed, and surveyed the regional distribution. Then, the presumption result of those environmental capacities was arranged by GIS. In addition, the amount of the ecosystem damage was presumed as cost necessary though a symbolical living thing for the retreat because of the base line by the heavy oil drifting ashore was recovered. By comparing the vegetation line and the surveying data which shows environmental capacity, the retreat areas of the vegetation were 1100-1200 $m^2$. When the amount of damage on the ecosystem of the NAHODKA oil-spill accident was presumed based on the retreat area of this vegetation and the restoration cost, the amount of damage within Shioya beach which 150m in the surveying range became 2 to 2.5 million Yen. Because the extension distance from the Shioya beach to the Katano beach was about 3,500m, the amount of damage became about 46 to 65 million Yen. As a result of calculation for the amount of damage on the ecosystem of the NAHODKA oil-spill accident, it was estimated approximately 1,400 to 2,000 million Yen in the shoreline of Ishikawa Pref., because the total extension of beaches in Ishikawa Pref. is about 110km.

• Genomics & Informatics
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• 제13권3호
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• pp.81-85
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• 2015

Molecular characterization technology in genetically modified organisms, in addition to how transgenic biotechnologies are developed now require full transparency to assess the risk to living modified and non-modified organisms. Next generation sequencing (NGS) methodology is suggested as an effective means in genome characterization and detection of transgenic insertion locations. In the present study, we applied NGS to insert transgenic loci, specifically the epidermal growth factor (EGF) in genetically modified rice cells. A total of 29.3 Gb (${\sim}72{\times}coverage$) was sequenced with a $2{\times}150bp$ paired end method by Illumina HiSeq2500, which was consecutively mapped to the rice genome and T-vector sequence. The compatible pairs of reads were successfully mapped to 10 loci on the rice chromosome and vector sequences were validated to the insertion location by polymerase chain reaction (PCR) amplification. The EGF transgenic site was confirmed only on chromosome 4 by PCR. Results of this study demonstrated the success of NGS data to characterize the rice genome. Bioinformatics analyses must be developed in association with NGS data to identify highly accurate transgenic sites.

• 인터넷정보학회논문지
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• 제25권1호
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• pp.69-78
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• 2024

최근 소비자들은 환경, 사회, 지배구조 관련 정보를 확인하고 더 나은 사회적 가치와 환경 친화적인 제품을 선택하려는 경향이 증가되고 있다. 본 논문에서는 GraphSAGE와 GAT를 결합한 모델인 MultiSAGE를 활용하여 최근 소비 트렌드인 가치소비에 맞추어 ESG 지표를 적용한 상품 추천 시스템을 제안하였다. 이를 위하여 한국 ESG 기준원에서 수집한 2022년 1,033개 기업의 ESG 등급 데이터와 실제 N기업의 쇼핑의 상품 데이터를 Heterogeneous Graph 형식의 데이터로 바꾸는 데이터 처리 과정과 MultiSAGE를 적용하여 머신 러닝에 적용하고, 특정 상품을 입력하면 그 상품의 친환경 대체재를 추천해주는 추천 시스템을 구현하였다. 구현결과, 소비자들은 기업의 ESG지표를 적용한 제품을 쉽게 비교하여 구매할 수 있고, 이를 통해 사회적 가치와 환경친화적인 제품을 추천하는 시스템에 활용될 것으로 기대한다.

• 정보교육학회논문지
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• 제24권2호
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• pp.189-199
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• 2020

본 연구는 "디지털 환경권"이라는 새로운 권리 개념 정립을 통해 정보교과 강화의 필요성을 역설하고 정보교과 내 정보문화소양의 교육구성 모델 개선 제안을 목적으로 한다. 디지털 환경권 개념 도입을 통하여 정보교과를 필수교과목화 하기 위한 논리적 근거를 제공하고 정보 교과 내 정보문화소양의 구성을 재체계화함으로써 디지털 시민으로서 학생이 디지털 환경을 살아가는데 필요한 역량 제고에 기여하고자 한다. 이에 대한 연구로 디지털 환경에서 요구되는 권리 개념의 논리를 분석하고 디지털 환경권 개념을 정립한다. 그리고 디지털 환경 전환과 관련하여 미국, 호주, 일본 등의 주요국에서 실행하고 있는 관련 교육과정을 분석함으로써 정보교과의 교육구성 개선안을 도출한다. 연구 결과는 다음과 같다.: 첫째, 디지털 환경권은 '쾌적하고 안전한 디지털 환경을 누릴 권리' 이다. 둘째, 디지털 환경권의 세분화된 구성요소로는 디지털 환경을 위한 권리(사이버윤리), 디지털 환경의 권리(사이버안전), 디지털 환경에 대한 권리(사이버보안)가 있다. 셋째, 주요국에서는 정보 관련 교육 내용으로 디지털시민성, 코드 윤리, 그리고 신기술 보안에 대해 다양한 교육구성이 이루어지고 있다.

• 생태와환경
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• 제54권3호
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• pp.151-155
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• 2021

국내 생태계의 환경유전자 적용도 가속화되고 있으나 생산된 데이터를 처리하고 분석하는 데 한계를 느끼고 있으며, 분석 생산된 생물데이터의 신뢰성에 대한 의구심이 제기되기도 하고 시료 매체(대상 시료, 물, 공기, 퇴적물, 위내용물, 분변 등) 간의 방법에 따른 차이와 분석 방법의 정량화와 개선 등이 필요한 상태이기도 하다. 따라서 국내 생태계의 환경유전자를 활용한 생물다양성 연구의 신뢰성과 정확성을 확보하기 위해서는 생태분류학으로 축적된 데이터베이스를 적극적으로 활용하여 검증 절차를 거치고, 유전자 서열 분석으로 높아진 데이터의 해상력을 전문가들이 검증하는 과정이 반드시 필요하다. 환경유전자 연구는 분자생물학적인 기술 적용으로만 해결될 수 없으며, 생산된 데이터의 신뢰성을 확보하기 위한 생태-분류-유전학-인포메틱스 등 학제 간의 연구 협력이 중요하며, 다양한 매체를 다루는 연구자들이 함께 접근할 수 있는 정보 공유 플랫폼이 절실한 분야이며, 발전의 속도도 급격하게 진행될 것이고 축적되는 데이터는 수년 내에 빅테이터로서 성장할 수 있을 것으로 기대된다.

• Genomics & Informatics
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• 제8권4호
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• pp.177-184
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• 2010

The target of rapamycin (TOR) signaling pathway is a conserved pathway that regulates eukaryotic cell growth in response to environmental cues. Chemical genomic approaches that profile rapamycin sensitivity of yeast deletion strains have given insights into the function of TOR signaling pathway. In the present study, we analyzed the rapamycin sensitivity of yeast deletion library strains on synthetic medium. As a result, we identified 130 strains that are hypersensitive or resistant to rapamycin compared with wild-type cells. Among them, 36 genes are newly identified to be related to rapamycin sensitivity. Moreover, we found 16 strains that show alteration in rapamycin sensitivity between complex and synthetic media. We suggest that these genes may be involved in part of TOR signaling activities that is differentially regulated by media composition.

• Genomics & Informatics
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• 제14권4호
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• pp.241-254
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• 2016

Environmental microbes like Bordetella petrii has been established as a causative agent for various infectious diseases in human. Again, development of drug resistance in B. petrii challenged to combat against the infection. Identification of potential drug target and proposing a novel lead compound against the pathogen has a great aid and value. In this study, bioinformatics tools and technology have been applied to suggest a potential drug target by screening the proteome information of B. petrii DSM 12804 (accession No. PRJNA28135) from genome database of National Centre for Biotechnology information. In this regards, the inhibitory effect of nine natural compounds like ajoene (Allium sativum), allicin (A. sativum), cinnamaldehyde (Cinnamomum cassia), curcumin (Curcuma longa), gallotannin (active component of green tea and red wine), isoorientin (Anthopterus wardii), isovitexin (A. wardii), neral (Melissa officinalis), and vitexin (A. wardii) have been acknowledged with anti-bacterial properties and hence tested against identified drug target of B. petrii by implicating computational approach. The in silico studies revealed the hypothesis that lpxD could be a potential drug target and with recommendation of a strong inhibitory effect of selected natural compounds against infection caused due to B. petrii, would be further validated through in vitro experiments.

• Genomics & Informatics
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• 제5권4호
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• pp.152-160
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• 2007

Most common diseases are caused by multiple genetic and environmental factors. Among the genetic factors, single nucleotide polymorphisms (SNPs) are common DNA sequence variations in individuals and can serve as important genetic markers. Recently, investigations of gene-based and whole genome-based SNPs have been applied to association studies for marker discovery. However, SNPs are so population-specific that the association needs to be verified. Fifty-five genes and 384 SNPs were selected based on association with disease. Genotypes of 337 SNPs in candidate genes were determined using Illumina Sentrix Array Matrix (SAM) chips by an allele-specific extension method in 364 unrelated Korean individuals. Allelic frequencies of SNPs were compared with those of other populations obtained from the International HapMap database. Minor allele frequencies, linkage disequilibrium blocks, tagSNPs, and haplotypes of functional candidate SNPs in 55 genetic disease-associated genes were provided. Our data may provide useful information for the selection of genetic markers for gene-based genetic disease-association studies of the Korean population.

• Journal of Preventive Medicine and Public Health
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• 제50권4호
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• pp.274-277
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• 2017

Objectives: Legionnaires' disease (LD) is a severe type of pneumonia caused by inhalation of aerosols contaminated with Legionella. On September 22, 2016, a single case of LD was reported from a newly built apartment building in Gyeonggi province. This article describes an epidemiologic investigation of LD and identification of the possible source of infection. Methods: To identify the source of LD, we interviewed the patient's husband using a questionnaire based on the Legionella management guidelines from the Korea Centers for Disease Control and Prevention. Water samples from the site were collected and analyzed. An epidemiological investigation of the residents and visitors in the apartment building was conducted for 14 days before the index patient's symptoms first appeared to 14 days after the implementation of environmental control measures. Results: Legionella pneumophila serogroup 1 was isolated from the heated-water samples from the patient's residence and the basement of the apartment complex. Thirty-two suspected cases were reported from the apartment building during the surveillance period, yet all were confirmed negative based on urinary antigen tests. Conclusions: The likely source of infection was the building's potable water, particularly heated water. Further study of effective monitoring systems in heated potable water should be considered.

• Journal of Microbiology and Biotechnology
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• 제16권12호
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• pp.1961-1967
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• 2006

Levels of ethyl carbamate, a potential carcinogen produced naturally during fermentation, in major Korean fermented foods and alcoholic beverages were determined by GC/MS/SIM, and their average daily intake and excess cancer risk in Korean people were estimated. In GC/MS/SIM analysis n.d.-4.26, 1.40-58.90, n.d.-3.76, n.d.-1.87, and 0.40-10.07 $\mu$g/kg of ethyl carbamate were detected in kimchi, soy sauces, fermented pastes, fermented dairy products, and alcoholic beverages, respectively. The average daily intake of ethyl carbamate and excess cancer risk through major Korean fermented foods and alcoholic beverage consumption were 6.0 ng/kg bw/day and $3.0\times10^{-7}$, respectively for the average Korean person aged 3-64 years, and were mainly contributed by Chinese cabbage kimchi, soy sauces, and Soju.