• 제목/요약/키워드: Environmental hormone

검색결과 286건 처리시간 0.024초

Regulation of hormone-related genes involved in adventitious root formation in sweetpotato

  • Nie, Hualin;Kim, Sujung;Lee, Yongjae;Park, Hyungjun;Lee, Jeongeun;Kim, Jiseong;Kim, Doyeon;Kim, Sunhyung
    • Journal of Plant Biotechnology
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    • 제47권3호
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    • pp.194-202
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    • 2020
  • The sweetpotatoes (Ipomoea batatas) generate adventitious roots (ARs) from cut stems that develop into storage roots and make for an important means of propagation. However, few studies have investigated the hormones involved in AR development in sweetpotato. In this study, the expression patterns of hormone-related genes involved in AR formation were identified using the transcriptome data. RNA-seq data from stems grown for 0 and 3 days after cutting were analyzed. In addition, hormone-related genes were identified among differentially expressed genes (DEGs) and filtered genes, and cluster analysis was used to characterize expression patterns by function. Most hormone-related regulated genes expressed 3 days after growing the cut stems were abscisic acid (ABA)-related genes, followed by ethylene- and auxin-related genes. For ABA, the biosynthesis genes (including genes annotated to NINE-CIS-EPOXYCAROTENOID DIOXYGENASE 3 (NCED3)) and signal transduction and perception genes (including genes annotated to PROTEIN PHOSPHATASE 2Cs (PP2Cs)) tended to decrease. Expression patterns of auxin- and ethylene-related genes differed by function. These results suggest that ABA, auxin, and ethylene genes are involved in AR formation and that they may be regulated in a hormone function-dependent manner. These results contribute to the identification of hormone functions during AR formation and may contribute to understanding the mechanism of AR formation in the sweetpotato.

유기주석화합물의 독성에 대한 홍삼의 방어효과 - 면역 및 성 호르몬물질 중심으로 - (The protective effect of Red Giseng on the organotin compounds(TBTO) poison : Focusing on the Immunity and sex hormone)

  • 최한영
    • 환경위생공학
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    • 제16권3호
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    • pp.8-13
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    • 2001
  • This study was carried out effect of red ginseng extract(1.0g/kg) on organotin compounds (10, 20 and 40 mg/kg) which poisons against some organs like thyroid gland, liver, kindey, testis, ovary, serum immuinty and sex hormone activity of rats were examinned by gastric tubing for 3 weeks. The weight of each organ in TBTO treated group were significantly increased other organs which excepted kinedy in males and only liver in females.(p<0.05, p<0.01). In case of Immunity activity of each sex, IgM level was small change comparsion with that of control group in all sex. but IgG level was significantly decreased females rather than males comparsion with that of control group.(p<0.05, p<0.01) In case of sex hormone activity, the testosterone activity of males and the estradiol activity of females were significantly decreased rather than the control group. on the other hand, red singsong treated group was only significantly increased estradiol activity.( p<0.05, p<0.01)

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Chemopreventive effect of Ginkgo biloba extract on breast cancer: Regulation of estrogen level

  • Oh, Seung-Min;Kim, Yun-Hee;Chung, Kyu-Hyuck
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.282.2-283
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    • 2002
  • In situ and circulating estrogen is the most important endocrine hormone that promotes the growth of hormone-dependent breast cancer. Consequently. decrease of estrogen on in situ and circulation can inhibit breast cancer. Estrogen is mainly produced by the ovary in premenopausal women and by peripheral tissues such as adipose tissues in postmenopausal women. The cytochrome p450 (CYP19), aromatase. is a key enzyme in the synthesis of estrogen hormones. (omitted)

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홍삼 투여가 TBTO의 성호르몬 활성에 미치는 영향 (Effect on Sex hormone activity of TBTO against injected red Ginseng extract)

  • 최한영
    • 환경위생공학
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    • 제21권2호
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    • pp.30-35
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    • 2006
  • The purpose of this study finds out the effect of red ginseng extract (1.0g/kg) on TBTO (10, 20, and 40mg/kg) which poisons against some organs like thyroids gland, liver, kidney, testis, ovary, sex hormone activity of rats are examined by gastric tubing for 3 weeks. The weight of each organ in treated group were increased, especially liver in female and those of testis in males were significantly increased at 10, 20 and 40mg/kg (P<0.05, P<0.01). In case of sex hormone activity of each sex, the estradiol activity of female and testosterone activity of males were significantly decreased rather than the control group (P<0.05, P<0.01) According to between the TBTO treated group and 10+ rGe group of the testosterone activity each sex were significantly increased (P<0.01).

The relationship between shift work pattern and thyroid stimulating hormone in female workers

  • Hun Jeong;Chang Ho Chae;Jun Ho Lee;Hyo Won Chong
    • Annals of Occupational and Environmental Medicine
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    • 제35권
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    • pp.14.1-14.10
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    • 2023
  • Background: Shift work is known to cause changes in the circadian rhythm of the human body and adversely affect not only physical health but also mental health. Some studies have demonstrated the correlation between shift work and thyroid stimulating hormone (TSH), a hormone that changes according to the diurnal rhythm, but few studies have reported the different TSH levels according to the shift work type. This study aimed to investigate changes in TSH according to the shift work type. Methods: This study included 1,318 female workers who had a medical checkup at a university hospital in Changwon from 2015 to 2019. Shift work types were classified as non-shift work, regular 2 shifts, and irregular three shifts, and a TSH ≥ 4.2 mIU/L was defined as abnormal. A general linear model (GLM) was used to compare the TSH levels and the risk of subclinical hypothyroidism in each year, and a binary logistic analysis was performed using a generalized estimation equation (GEE) to compare the risk of subclinical hypothyroidism over the 5-year period. Results: Of the 1,318 participants included in this study, 363, 711, and 244 were non-shift, two-shift, and irregular three-shift workers, respectively. In the GEE analysis, after adjusting for age, body mass index, smoking, and alcohol consumption, the odds ratios (ORs) were 1.81 (95% confidence interval [CI]: 1.15-2.86; p = 0.011) in 2 shifts and 2.02 (95% CI: 1.23-3.32; p = 0.006) in irregular three shifts, compared to non-shift. Conclusions: Our results showed that shift work had a higher risk of subclinical hypothyroidism than non-shift work and that there was a significant difference in the risk of subclinical hypothyroidism according to the shift work type. These findings suggest that the shift work type can be considered in future thyroid function tests and evaluations.

Bis(tributyltin) oxide가 랫드의 면역 및 성호르몬 활성에 미치는 영향 (Studies on Immunity and Sex Hormone Activity of Bis(tributyltin) oxide)

  • 최한영;나규환
    • 한국환경보건학회지
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    • 제25권3호
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    • pp.89-93
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    • 1999
  • The purpose of this study finds out the effect of red ginseng extract(1.0 g/kg) on bis(tributyltin)oxide(TBTO)(10, 20 and 40 mg/kg) which poisons against some organs like thyroid gland, liver, kidney, testis, ovary. Serum immunity and sex hormone activity of rats are examined by gastric tubing for 3 weeks. The weights of each in treated group were increased, especially liver in females and those of testis in males were signignificantly increased at 10, 20 and 40 mg/kg (P<0.05, P<0.01). In group treated with TBTO(10, 20 and 40 mg/kg) for females, the serum IgG level was significantly reduced in comparison with control group(P<0.05). The group of females which were poisonned by TBTO and rGe was significantly recovered in TBTO 10 mg/kg + rGe 1.0 g/kg and TBTO 20 mg/kg + rGe 1.0 g/kg. In case of sex hormone activity of each sex, the estradiol activity of females and testosterone activity of males were signignificantly decreased rather than the control group. And control group by bis(tributyltin) oxide and red ginseng extract is just increased estiradiol activity.

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Influence of Occupational Exposure to Bisphenol A on the Sex Hormones of Male Epoxy Resin Painters

  • Cha, Bong-Suk;Koh, Sang-Baek;Park, Jun-Ho;Eom, Ae-Yong;Lee, Kang-Myeung;Choi, Hong-Soon
    • Molecular & Cellular Toxicology
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    • 제4권3호
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    • pp.230-234
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    • 2008
  • Epidemiological studies demonstrate an adverse effect of several environmental and occupational exposures on male sex hormone. Bisphenol A (BPA) is a weak estrogen and a widely used industrial chemical. Epoxy resin painters may be continuously exposed to BPA at high concentrations. The effect of occupational exposure of BPA on male reproduction was examined by measuring the urinary BPA, testosterone and gonadotropic hormones of epoxy resin painters in the shipyard. The painters had significantly higher concentrations of urinary BPA (2.61${\pm}$1.08 ${\mu}g$/g creatinine) than controls (1.38${\pm}$0.5 9 ${\mu}g$/g creatinine). In serum, the testosterone level of painters was significantly decreased but the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels of painters were significantly higher than controls. Occupational exposure to BPA influences testosterone and gonadotropic hormones in male workers.

Analyse the interaction of Combined-pesticide

  • Song, Xiao Xiao
    • 한국환경보건학회:학술대회논문집
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    • 한국환경보건학회 2004년도 International Conference Current Challenges and Advances in Environmental Health
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    • pp.43-44
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    • 2004
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