Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Chemopreventive effect of Ginkgo biloba extract on breast cancer: Regulation of estrogen level

  • Oh, Seung-Min (Environmental and Preventive Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Kim, Yun-Hee (Environmental and Preventive Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Chung, Kyu-Hyuck (Environmental and Preventive Pharmacy, College of Pharmacy, Sungkyunkwan University)
  • Published : 2002.10.01
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Abstract

In situ and circulating estrogen is the most important endocrine hormone that promotes the growth of hormone-dependent breast cancer. Consequently. decrease of estrogen on in situ and circulation can inhibit breast cancer. Estrogen is mainly produced by the ovary in premenopausal women and by peripheral tissues such as adipose tissues in postmenopausal women. The cytochrome p450 (CYP19), aromatase. is a key enzyme in the synthesis of estrogen hormones. (omitted)

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