• Molecules and Cells
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• v.40 no.10
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• pp.697-705
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• 2017

The maintenance of inorganic phosphate (Pi) homeostasis is essential for plant growth and yield. Plants have evolved strategies to cope with Pi starvation at the transcriptional, post-transcriptional, and post-translational levels, which maximizes its availability. Many transcription factors, miRNAs, and transporters participate in the Pi starvation signaling pathway where their activities are modulated by sugar and phytohormone signaling. Environmental stresses significantly affect the uptake and utilization of nutrients by plants, but their effects on the Pi starvation response remain unclear. Recently, we reported that Pi starvation signaling is affected by abiotic stresses such as salt, abscisic acid, and drought. In this review, we identified transcription factors, such as MYB, WRKY, and zinc finger transcription factors with functions in Pi starvation and other environmental stress signaling. In silico analysis of the promoter regions of Pi starvation-responsive genes, including phosphate transporters, microRNAs, and phosphate starvation-induced genes, suggest that their expression may be regulated by other environmental stresses, such as hormones, drought, cold, heat, and pathogens as well as by Pi starvation. Thus, we suggest the possibility of cross-talk between Pi starvation signaling and other environmental stress signaling pathways.

• Korea Trade Review
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• v.46 no.2
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• pp.121-140
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• 2021

The ship recycling or scrap is a phenomenon in the process of vessels life cycle has ended in the shipping industry. Scrap are greatly affected by freight rates due to ship demands. Not only that, environmental regulation and economic scale vessel demand are processes that must exist in the shipping industry as they obtain management for existing vessels. In the past, shipbreaking yard had tried to work without protection for poverty, without poor working conditions and facilities to prevent the emission of harmful substances. However, the issue of environmental pollution has been raised the Basel and Hong Kong Convention have been adopted, and a new replacement of the ship scrap that induces serious pollution is required. In this study, 165 countries were analyzed to confirm the importance of determining the ship solution. As a result of the analysis, it was found that the Environmental Performance Index, which is a measure of environmental regulation, is the most influential factor of ship scrapped volume. The determinant of whether lower labor cost can be secured is more correlated with population than GDP per capita. The implications of the results of the regression analysis mean that if environmental regulations for ship scrap of the future are strengthened, the status of Bangladesh and Pakistan, which currently account for half of the world's ship recycling, may change.

• Toxicological Research
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• v.29 no.3
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• pp.165-172
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• 2013

Acetaminophen (APAP) known as paracetamol is the main ingredient in Tylenol, which has analgesic and anti-pyretic properties. Inappropriate use of APAP causes major morbidity and mortality secondary to hepatic failure. Overdose of APAP depletes the hepatic glutathione (GSH) rapidly, and the metabolic intermediate leads to hepatocellular death. This article reviews the mechanisms of hepatotoxicity and provides an overview of current research studies. Pharmacokinetics including metabolism (activation and detoxification), subsequent transport (efflux)-facilitating excretion, and some other aspects related to toxicity are discussed. Nuclear factor erythroid 2-related factor 2 (Nrf2)-regulated gene battery plays a critical role in the multiple steps associated with the mitigation of APAP toxicity. The role of Nrf2 as a protective target is described, and potential natural products inhibiting APAP toxicity are outlined. This review provides an update on the mechanism of APAP toxicity and highlights the beneficial role of Nrf2 and specific natural products in hepatoprotection.

• Environmental and Resource Economics Review
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• v.9 no.5
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• pp.903-924
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• 2000

This paper examines the alternative method to measure the state of overall economic activity. The macroeconomic variables, used for business cycle, take more than a month after a period for collection and aggregation. The electricity generation data is compiled in mechanical ways just after the period. Based on this fact, we develop the two stage estimation method for coincident economic indicators in order to detect the business cycle in an earlier period, using Stock-Watson's Dynamic Factor Model. Using monthly data from 1970 to 1999, it is found that the experimental coincidence economic indicators are well-fitted to data and also that the estimates of two stage estimation method have good explanatory power, equivalent to the experimental coincidence economic indicators. While the RMSE of coincidence economic indicators is found to be 1.27%, that of the experimental coincidence economic indicators is found to be 1.31% and that of the two stage estimation method is around 1.44%. If we take consideration into the fact that it measures the business cycle in one month earlier, we come to the conclusion that the two stage estimation is of great use.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.15 no.1
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• pp.13-18
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• 2012

The pathogenesis of inflammatory bowel diseases is not very well understood; it is currently thought to be caused by the interaction between genetic factors, environmental factors, intestinal microbes, and immune factors. Biological agents such as anti-tumor necrosis factor (anti-TNF) are widely being used as therapeutic agents. Infliximab, a chimeric monoclonal IgG1 antibody against tumor necrosis factor, has been demonstrated to have an effect in the induction and maintenance of remission in Crohn's disease in children. The effects of biological agents, typified by anti-TNFs, in inflammatory bowel disease in children; the recent concern on the administration of biological agents in combination with immunomodulators; and 'Top-down' therapy are some of the topics covered in this review.

• Biotechnology and Bioprocess Engineering:BBE
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• v.8 no.6
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• pp.313-321
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• 2003

This review summarizes the recent advances in high-density algal cultures in the field of algal biotechnology. Photobioreactor engineering for economical and effective utilization of algae and its products has made impressive and promising progress. Bioprocess engineers have expedited the design and the operation of algal cultivation systems. Many of them in use today are open systems due to cost considerations, and closed photobioreactors have recently attracted a considerable attention for the production of valuable biochemicals or for special applications. For high-density cultures, the optimization of environmental factors in the photobioreactors have been explored, including light delivery, CO$_2$and O$_2$gas transfer, medium supply, mixing and temperature. It is expected that further advanced photobioreactor engineering will enable the commercialization of noble algal products within the next decade.

• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.1
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• pp.1-6
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• 2013

In this paper, we review an outline as premise for environmental analysis of green IT which has basic stage through the world in order to make knowledge map of green IT. We can analyze genuine environment for green IT based on this premise, and we expect that we can also use to analyse power of competition based on intellectual property after performing these environmental analysis.

• The Journal of the Korean dental association
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• v.50 no.8
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• pp.465-473
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• 2012

Prognosis is an anticipation of the probable response to periodontal therapy and a long-term prospect for maintaining a functional dentition. Hopeless cases or cases of simple gingivitis without systemic diseases generally have little problem to establish definite prognoses. However, it might become somewhat challenging to determine their prognoses in borderline cases. A risk factor for periodontal disease may be environmental, behavioral, or biologic factors that can be defined as an occurrence has been associated with destructive periodontitis. Some risk factors are modifiable, while others cannot be modified. Modifiable risk factors are environmental or behavioral in nature in contrast non-modifiable risk factors are usually intrinsic to the individual and therefore not easily changed. In this review, we will assess the various modifiable or non-modifiable risk factors for susceptibility 10 periodontal diseases.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.5
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• pp.617-627
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• 2018

Environmental stressors like pathogens and toxins may depress the animal immune system through invasion of the gastrointestinal tract (GIT) tract, where they may impair performance and production, as well as lead to increased mortality rates. Therefore, protection of the GIT tract and improving animal health are top priorities in animal production. Being natural-sourced materials, phytochemicals are potential feed additives possessing multiple functions, including: anti-inflammatory, anti-fungal, anti-viral and antioxidative properties. This paper focuses on immunity-related physiological parameters regulated by phytochemicals, such as carvacrol, cinnamaldehyde, curcumin, and thymol; many studies have proven that these phytochemicals can improve animal performance and production. On the molecular level, the impact of inflammatory gene expression on underlying mechanisms was also examined, as were the effects of environmental stimuli and phytochemicals in initiating nuclear factor kappa B and mitogen-activated protein kinases signaling pathways and improving health conditions.

• Development and Reproduction
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• v.17 no.3
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• pp.149-177
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• 2013

Living beings are surrounded by various changes exhibiting periodical rhythms in environment. The environmental changes are imprinted in organisms in various pattern. The phenomena are believed to match the external signal with organisms in order to increase their survival rate. The signals are categorized into circadian, seasonal, and annual cycles. Among the cycles, the circadian rhythm is regarded as the most important factor because its periodicity is in harmony with the levels of melatonin secreted from pineal gland. Melatonin is produced by the absence of light and its presence displays darkness. Melatonin plays various roles in creatures. Therefore, this review is to introduce the diverse potential ability of melatonin in manifold aspects in living organism.