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http://dx.doi.org/10.5713/ajas.17.0657

Immunomodulatory effects of phytogenics in chickens and pigs - A review  

Huang, C.M. (Department of Animal Science, National Chung Hsing University)
Lee, T.T. (Department of Animal Science, National Chung Hsing University)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.31, no.5, 2018 , pp. 617-627 More about this Journal
Abstract
Environmental stressors like pathogens and toxins may depress the animal immune system through invasion of the gastrointestinal tract (GIT) tract, where they may impair performance and production, as well as lead to increased mortality rates. Therefore, protection of the GIT tract and improving animal health are top priorities in animal production. Being natural-sourced materials, phytochemicals are potential feed additives possessing multiple functions, including: anti-inflammatory, anti-fungal, anti-viral and antioxidative properties. This paper focuses on immunity-related physiological parameters regulated by phytochemicals, such as carvacrol, cinnamaldehyde, curcumin, and thymol; many studies have proven that these phytochemicals can improve animal performance and production. On the molecular level, the impact of inflammatory gene expression on underlying mechanisms was also examined, as were the effects of environmental stimuli and phytochemicals in initiating nuclear factor kappa B and mitogen-activated protein kinases signaling pathways and improving health conditions.
Keywords
Phytogenics; Phytochemicals; Immune Response; Inflammatory Cytokines; Domestic Animals;
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