• Proceedings of the KSME Conference
• /
• 2005.11a
• /
• pp.128.1-128.1
• /
• 2005

• Proceedings of the Korean Nuclear Society Conference
• /
• 2005.05a
• /
• pp.489-490
• /
• 2005

• Environmental Mutagens and Carcinogens
• /
• v.16 no.1
• /
• pp.13-18
• /
• 1996

One mechanism of free-radical production by ethanol is suggested to be through the intracellular conversion of XDH to XO by increased ratio of NADH to NAD. The major mechanism for physiological compensation of cytosolic NADH/NAD balance is the malate/aspartate shutfie. Therefore, it is important to develop the method to improve the efficiency of malate/aspartate shuttle in ethanol metabolism. In the present study, various amino acids and organic acid involved in the shuttle were tested for their functional efficiency in modulating shuttle in the ethanol-perfused rat liver. The rate of ethanol oxidation in the liver perfused with aspartate alone or aspartate in combination with pyruvate, respectively, was increased by about 10% compared to control liver, but not in the tissues perfused with glummate, cysteine or pyruvate alone. Though glummate, cysteine and pyravate did not affect the ethanol oxidation significanfiy, they showed some suppresive effect on the ethanol-induced radical generation monitored by protein carbonylation analysis. Among the tested components, aspartate is confirmed to be the most efficient as a metabolic regulator for both ethanol oxidation and ethanol-induced oxidative stress in our perfusion system. These effects of aspartate would result from NAD recycling by its supplementation through the coupled aspartate aminotransferase/malate dehydrogenase reactions and the malate-aspartate shuttle.

• The Journal of the Korea Contents Association
• /
• v.21 no.12
• /
• pp.803-815
• /
• 2021

As the world's aging population increases, the aging problem in China, which has a huge population, has reached a serious situation. Therefore, this study intends to present the CCRC model of smart home care. Seven application factors of CCRC of smart home care and problems of CCRC of smart home care in China were derived through theoretical review and case analysis. Based on this, this study presented a value proposition for the 7 application elements of smart home care CCRC tailored to China's aging status and future technology demand. First, it improves the environmental atmosphere and increases the comfort of the spatial environment. Second, we value the physical and environmental safety of the elderly. Third, online convenience services are provided. Fourth, we guarantee the health and psychological health of the elderly. Fifth, it increases the efficiency of responding to unexpected situations. Sixth, predict the physical condition and surrounding environment of the elderly. Seventh, add more recreational rides. Through this, we expect to improve the quality of life by providing a safe and comfortable smart service environment for the elderly.

• Journal of The Korea Institute of Healthcare Architecture
• /
• v.17 no.2
• /
• pp.7-16
• /
• 2011

The death toll of the elderly by accidents in 2007 takes 6.5% of total death toll. The lost income from this is estimated to be 17 trillion and 511 billion won. According to CISS of Korea Consumer Protection Board, the number of safety related accidents of the elderly at home in 2006 was 486 cases in 2006 and has gradually increased every year. This thesis created 115 guidelines at 14 spaces as facility evaluation index evaluating the aging friendliness of the facility and safety related accidents generated at elderly resident welfare facility, examined influence variables of safety related accidents with 191 elderly including demographic variable, physical skill variable, social psychological variable and facility environmental variables, and then verified relevance between safety accidents and each influence variable. As a result, it was verified through ANOVA test of SAS Package Program and $x^2$- test that facility environmental variable would be closely related to the accident. In this regard, this study newly proposes the facility standards of aging friendly facility by supplementing them with contents and guidelines of facility evaluation table as ways to reduce safety related facility of the elderly.

• Journal of Microbiology and Biotechnology
• /
• v.20 no.8
• /
• pp.1189-1191
• /
• 2010

In an ongoing investigation of compounds from natural products that exhibit anti-aging properties, hydroxyhibiscone A (1), a new furanosesquiterpenoid, together with hibiscone D (2), was isolated from the root bark of Hibiscus syriacus. Utilizing UV, IR, NMR, and MS spectroscopic analyses, these chemical structures were revealed. Compounds 1 and 2 were found to posses significant anti-aging properties on the human neutrophil elastase (HNE) assay, exhibiting HNE inhibitory activities with $IC_{50}$ values of 5.2 and 4.6 ${\mu}M$, respectively.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2009.11a
• /
• pp.443-446
• /
• 2009

In this study, a series of degradation test for structural adhesives was performed to investigate the possibility of replacement of the alternative adhesives to the conventional adhesives. Four types of the adhesives were exposed to combined environmental conditions over 1000 hours at an accelerated aging tester, which can simulate natural weather conditions such temperature, moisture and ultraviolet. Mechanical and chemical properties of the adhesives were evaluated through material testing system and FT/IR spectrometer. According to the results, the conventional adhesives can be replaced by the alternative adhesives because the alternative adhesives were more stable to environmental conditions rather than the conventional adhesives.

• Journal of Preventive Medicine and Public Health
• /
• v.46 no.sup1
• /
• pp.50-54
• /
• 2013

Out-of-home mobility is necessary for accessing commodities, making use of neighborhood facilities, and participation in meaningful social, cultural, and physical activities. Mobility also promotes healthy aging as it relates to the basic human need of physical movement. Mobility is typically assessed either with standardized performance-based tests or with self-reports of perceived difficulty in carrying out specific mobility tasks. Mobility declines with increasing age, and the most complex and demanding tasks are affected first. Sometimes people cope with declining functional capacity by making changes in their way or frequency of doing these tasks, thus avoiding facing manifest difficulties. From the physiological point of view, walking is an integrated result of the functioning of the musculoskeletal, cardio-respiratory, sensory and neural systems. Studies have shown that interventions aiming to increase muscle strength will also improve mobility. Physical activity counseling, an educational intervention aiming to increase physical activity, may also prevent mobility decline among older people. Sensory deficits, such as poor vision and hearing may increase the risk of mobility decline. Consequently, rehabilitation of sensory functions may prevent falls and decline in mobility. To promote mobility, it is not enough to target only individuals because environmental barriers to mobility may also accelerate mobility decline among older people. Communities need to promote the accessibility of physical environments while also trying to minimize negative or stereotypic attitudes toward the physical activity of older people.

• Journal of Forest and Environmental Science
• /
• v.38 no.4
• /
• pp.290-301
• /
• 2022

Increasing life expectancy leads to a rise in the prevalence of aging-related mental diseases and a concomitant increase in the financial and societal pressures related to their prevention and management. This issue is attracting increasing attention from researchers. Therefore, this study aimed to determine whether a healing program in a forest environment is effective for improving cognitive function, depression, anxiety, and stress in elderly people. A nonequivalent control group pretest-posttest design was used. The experimental group consisted of 18 males and females aged 60 to 80 years who participated in a forest healing program for seven days, while the comparison group comprised 10 people with similar demographics. For the process of data analysis, this study performed a cross-analysis to determine the homogeneity of the data and carried out the Wilcoxon signed-rank test, a nonparametric statistical test, to verify the significance of each group. Participation in the forest healing program led to a significant improve-ment in cognitive function (p=0.030). The levels of depression decreased, but this result was not statistically significant. The levels of anxiety decreased significantly (p=0.004). The mean cortisol score, a measurement of stress, decreased, but it was not statistically significant. These findings confirmed the effectiveness of this program for improving certain mental conditions of elderly people, and affirmed that the use of long-term forest healing programs can be expected to alleviate national pressures created by aging societies.

• Journal of Korean Society of Water and Wastewater
• /
• v.36 no.3
• /
• pp.177-186
• /
• 2022

In this study, newly improved Ferron assay test haved on timed spectrometry was used for the determination of hyolrolytic Al species presented in PACl coagulant. The color development reagent ferron was prepared by using conventional method and two newly developed methods. Then the ferron assay test was used to compare and analyze the distribution of Al(III) hydrolyzed species presented in the prepared PACl and alum. The preparing method of reagent A required an aging period of 7 days by adding a hydroxylamine hydroxide and a 1,10-phenanthroline monohydrate reagent, whereas the preparing method of reagent B was used as a coloring agent immediately without aging time. The regression analysis between UV absorbance and Al concentrations of conventional method and newly developed method of ferron reagents in low-concentration aluminum solutions and high-concentration aluminum solutions, showed the correlation coefficients of 0.999 or higher, as showing high correlations of conventional method and newly developed method. Applying Ferron assay test, Al species in the PACls and alum were classified as Ala(monomeric Al), Alb (polymeric Al), and Alc (colloidal and precipitated Al). Distribution of Al(III) hydrolyzed species according to the preparation of ferron colorimetric reagents was similar.