• Parasites, Hosts and Diseases
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• 제48권2호
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• pp.121-126
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• 2010

To know the prevalence of Enterobius vermicularis infection and what are the most important risk factors, we evaluated the incidence and risk factors of enterobiasis among children attended in kindergartens in Busan metropolitan city, Republic of Korea. A total of 1,674 children from 21 kindergartens in 11 of 16 autonomous districts of Busan were evaluated for E. vermicularis infection by the cellotape anal swab technique. The overall egg-positive rate for E. vermicularis was 10.7% (179/1,674), and the prevalence of enterobiasis in each kindergarten ranged between 0% and 32.4%. There was an increasing tendency of the egg positive rate according to the population density; the higher the population density communities had, the higher egg-positive rate for E. vermicularis was detected (P = 0.001). Among personal hygiene factors involving children, thumb-sucking (P = 0.036) and fingernail-trimming (P = 0.024) were highly associated with enterobiasis. In addition, taking anthelmintic medications against E. vermicularis infection was strongly associated with enterobiasis (P = 0.014). Moreover, parents' knowledge of enterobiasis was correlated significantly with the incidence of enterobiasis of their children (P = 0.006). In conclusion, we need to consider not only personal hygiene but also parents' knowledge about enterobiasis as a factor in order to develop new strategies for elimination or to complete reduction of enterobiasis in Korea.

• Parasites, Hosts and Diseases
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• 제24권2호
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• pp.205-208
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• 1986

국민학교 학동에 있어서 요충감염율을 조사하기 위해 1985년 9월부터 11월까지 도시지역 국민학교 학동 326명, 농촌지역 학동 243명, 어촌지역 학동 291명을 대상으로 Graham 씨법으로 요충 충란 양성율을 조사하였다. 첫째 도시지역 학동의 요충 충란 양성율은 13.8%로써 농촌지역 학동에서의 55.6%, 어촌지역 학동 46.7%에 비해 월등히 낮았다. 둘째 남자학동의 요충 충란양성율 31.2%는 여자 학동에서의 43.5%에 비해 현저히 낮았다. 세째 국민학교 학동의 학년이 높아질수록 요충충란 양성율이 낮아졌으며, 이같은 성적은 남자와 여자학동 모두에서 공통적이었다.

• Parasites, Hosts and Diseases
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• 제51권1호
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• pp.139-142
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• 2013

Pinworm infection can occur through contact with contaminated surfaces followed by ingestion or even through inhalation of infective eggs. We have limited information regarding environmental contamination by eggs of Enterobius vermicularis. In order to determine environmental risk factors associated with the rate of E. vermicularis infection, we investigated possible environmental risk factors using a questionnaire from 46 kindergartens in 3 different cities of the southeast area of Korea. In total, using the cellotape anal swab technique, 3,422 children were examined for E. vermicularis infection. We evaluated E. vermicularis egg of books, educational materials, toys, room door handles, dusts of window edges, desks, chairs, tables, and dusts of classrooms. The overall egg-positive rate for E. vermicularis was 6.0%, and the prevalence of enterobiasis in each kindergarten ranged between 0% and 16.9%. We found that 78.9% of egg positive kindergartens were managed by private foundations, which was significantly higher, compared with kindergartens managed by public foundations or the nation. Compared with public or national kindergartens, most private kindergartens were located in residential areas and the number of children in these areas was significantly higher. In conclusion, numbers of children in kindergartens was found to be an environmental risk factor associated with transmission of enterobiasis in Korea.

• 대한약리학회지
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• 제12권1호
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• pp.69-73
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• 1976

A combined syrup preparation of pyrantel pamoate and oxantel pamoate containing 50mg/ml of respective anthelminthics was evaluated on the efficacy to treat the human intestinal nematodes. Total 24 cases were treated with oral administration of above preparation 10 mg/kg body weight by single dose. The results were summarized as follows: 1. Out of 21 cases of Ascaris lumbricoides infection, 19 (90.5%) turned to be egg negative on 21 days after treatment and egg-reduction rate was 99.7%. 2. 17 cases out of 19 cases infected with Trichocephalus trichiurus were egg negative after treatment (84.2%) and egg reduction rate was 60.6%. 3. As for Ancylostoma duodenale infection, egg negative conversion rate was 88.9% and egg reduction rate was 98.1% by single oral administration among 9 infected cases. 4. In Enterobius vermicularis infection, all of 17 cases gave negative anal swab on 21th day after the treatment. From the above results, it was assumed that the anthelminthic activities of pyrantel pamoate and oxantel pamoate were not potentiated by the mixture of two kinds of drugs but showed simple additive effect.

• Parasites, Hosts and Diseases
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• 제26권3호
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• pp.215-220
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• 1988

국내 일부 지역 국민학교 학동에 있어서 요충 감염상태를 알아보고자 하였다. 즉, 1984년 10월 서을 지역의 한 국민학교와 경기도 양주군의 한 국민학교, 1986년 10월 경기도 의정부의 한 국민학교에 대하여 항문주위 도말검사를 오전 9시∼12시 사이에 1회 실시하였다. 한편 1988년 10월 상기 국민학교 3학년 학동들에게 요충감염에 영향을 미칠 것으로 생각되는 가정환경 요인들에 대하여 설문 조사를 시행하였다. 국민학교 학동의 요충란 양성률은 평균 16.0%(2,156명 조사)였고 남자가 14.5%(1,118명), 여자 가 17.6%(1,038명)로서 여자에서 약간 높았다. 또 저학년보다 고학년에서 낮은 양성률을 보였다. 지역별로는 서울의 유현국민학교 학동이 13.6%로 가장 낮은 양성률을 보였고 경기도의 호암국민학교가 17.5%, 덕산국민학교가 17.6%의 양성률을 각각 보였다. 학동의 요충 감염에 영향을 미칠 것으로 생각되는 여러 가정환경 요인들중 가장의 직업, 형제수, 어린이 방의 유무, 목욕실 유무 등이 유의한 요인으로(p<0.1) 나타났다. 이상의 결과는 학동의 요충 감염이 아직도 높은 상황임을 보이고 있으나, 과거 10연전의 성적과 비교해 볼 때 감소되고 있으며, 특히 생활수준과 가정환경 요인의 개선이 감염률의 감소에 영향을 미치고 있음을 알 수 있었다.

• Parasites, Hosts and Diseases
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• 제53권4호
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• pp.497-499
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• 2015

To determine whether pinworm infections and head lice infestations spread among children in orphanages, 117 children from 4 orphanages in Busan-si and Ulsan-si, Korea, were examined for enterobiasis and head lice infestation between January and February 2014. The overall rate of Enterobius vermicularis egg positivity was 0.85%, whereas none of the children had head lice infestations. The rate of pinworm infection was much lower among the orphanage children compared to the rates observed in previous studies among kindergarten and primary school students. Moreover, the risk factors for enterobiasis were less frequent among these subjects than previously reported. The personal hygiene and health of the orphanage children were supervised by a regular, employed nurse through a health education program. In conclusion, pinworm infection was efficiently controlled among the children in orphanages, and this might be related to good personal hygiene practices in Korea.

• Parasites, Hosts and Diseases
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• 제59권4호
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• pp.421-426
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• 2021

A 12-year nationwide survey (2008-2019) was performed to investigate the prevalence of Enterobius vermicularis infection among preschool children in Seoul, 4 large cites (Busan, Incheon, Daegu, and Ulsan), and 9 provinces (grouped into 5 localities) in the Republic of Korea (=Korea). The survey was carried out once a year by 16 regional offices of the Korea Association of Health Promotion. The cello-tape perianal swab method (1 smear per child) was applied to detect eggs of E. vermicularis and other helminths. According to the results, the egg positive rate of E. vermicularis infection in 2008-2009 was 1.8-2.0%, but it decreased gradually to 0.6% in 2019 (P<0.05). The prevalence was significantly higher in boys (0.7-5.0%, mean 1.8%) than in girls (0.5-2.8%, mean 1.3%) (P<0.05). The 2 most southern localities, Jejudo (Province) and Jeolla-do (inclusive of Jeollabuk-do and Jeollanam-do) and a mid-western province, Gyeonggi-do, revealed higher prevalences, whereas Seoul and Gangwon-do showed lower prevalences. The results indicate that a low-grade prevalence of E. vermicularis infection (less than 4%) has been maintained for the recent 12 years among preschool children in Korea. Continuous monitoring of enterobiasis in the child age group is necessary in Korea.

• 농촌의학ㆍ지역보건
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• 제12권1호
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• pp.94-101
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• 1987

Enterobiasis is common helminthic infections found in man. But control of this disease is still troublesome because of its difficulty in the d diagnosis and prevention of infection. Considering the difficulty of accurate diagnosis of pinworm infection, which is very common and somewhat pathogenic, reevaluation of cellotape anal swab method for the diagnosis of enterobiasis was performed. A total of 147 children ranging the ages of 1-12 years in 3 orphanages in the suburbs of Seoul, Korea was subjected for this study. Repeated cellotape anal swabs were carried out against 70 children, 7 times for 3 days interval, in the morning 6am. Finally 10 mg/kg body weight pyrantel pamoates were given to all children including egg negative cases and whole stools of 3 following successive days were collected for the confirmation of residual worm ourden at the time of treatment. Cellotape anal swabs were also performed to another 77 children at 6am, 3pm, 9pm, twice for 3 days interval. The resultant findings were summarized as follows; 1) While the each time average detection rate of Enterobius egg was 28.8% in this study group, the accumulative detection rate up to 7th examination was 62.8%. The accumulative detection rate rose continuously up to 6th examination. 2) After administration of pyrantel pamoate 10 mg/kg body weight, final infection rate was increased to 72.9% by adding worm positive cases who didn't show any evidence of infection in the cellotape anal swabs. 3) Although pinworms were detected in 35 among 70 children treated, 7 cases (20%) of them were egg negative cases in 7 consecutive cellotape anal swabs. 4) Pinworms were expelleded in 14 (87.5%) among 16 children whose swab result was positive in the last examination which was done concurrently with drug administration. 5) Estimated infection rate calculated by best asymptotically normal estimate of Neuman from Moriya's modification revealed 71.5% similar to 72.9% of present results. 6) The result of anal swab performed at 6am was higher than that of 3pm or 8pm. In conclusion, cellotape anal swab method for Enterobius vermicularis infection was considered as method having relatively high positive accuracy. However to gain the reliable infection rate, at least 6 examination is required in the group with 25-30% infection rate by single swab. Moriya's modification of Neuman could be used efficiently in the mass control of this diease for the estimation of true infection rate of E. vermicularis in the sampled population.

• Parasites, Hosts and Diseases
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• 제35권4호
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• pp.265-270
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• 1997

초등학생 요충의 집단 검사와 치료시 진단 방법의 한계로 인하여 다음과 같은 점을 고려하여야 한다 즉. 항문 주위 도말법 양성인 어린이와 같은 반의 어린이를 동시에 치료할 필요가 있는가\ulcorner 양성인 어린이의 가족을 동시에 치료할 필요가 있는가\ulcorner 일년에 한 번 검사 후 투약하는 것보다 검사 후 양성자는 치료를 6개월 후 한 번 더 반복하는 것이 나은가\ulcorner 이런 질문에 답하기 위하여 양성자만 치료. 전 급우와 양성자 가족 동시 치료. 양성자와 양성자 가족 동시치료 이 세 가지를 한 번만 치료하는 것과 6개월 후에 반복하는 것으로 학생 집단을 나누어 일년 후 추적 검사하여 결과를 비교하였다. 그 결과. 모든 대상자를 양성자의 가족과 동시에 치료하는 것이 일년 후 양성률의 감소에 가장 효과적임을 알 수 있었다. 또한 요충 치료에서 감염자의 유입과 더불어 가족 감염이 매우 중요한 재감염의 요인임을 다시 한 번 확인할 수 있었다. 그러나 양성률이 30% 미만으로 낮은 집단에서는 양성자만 치료하는 것도 일년 뒤의 집단의 양성률을 낮추는 데 기여함을 알 수 있 었다. 앞으로 대상 양성률이 낮을 때의 상황에 대한 조사가 더 필요하다.

• Parasites, Hosts and Diseases
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• 제53권6호
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• pp.771-775
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• 2015

In order to determine the status of Enterobius vermicularis infection among schoolchildren in suburban areas of Myanmar, 761 primary schoolchildren in 3 different townships around Yangon City were subjected to a survey using cello-tape anal swabs. The subjected schoolchildren were 383 boys and 378 girls who were 5-7 years of age. Only 1 anal swab was obtained from each child. The overall egg positive rate of E. vermicularis was 47.2% (359 positives), and sex difference was not remarkable (48.6% in boys and 45.8% in girls). However, the positive rate was the highest in South Dagon (54.6%) followed by Hlaing Thayar (43.8%) and North Dagon (34.8%). This difference was highly correlated with the living standards of the people in each township. Nucleotide sequence of the 5S rDNA from the eggs on the cello-tape (2 children) revealed 99.7% identity with that of E. vermicularis reported in GenBank. The results indicated that E. vermicularis infection is highly prevalent among primary schoolchildren around Yangon, Myanmar.