• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1994년도 춘계학술대회
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• pp.115-118
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• 1994

Three-dimensional steady and pulsatile flows in an end-to-side anastomosis were investigated using a finite difference method in order to understand the flow dynamics in the preferential development of distal anastomotic intimal hyperplasia or thrombosis. Steady flow results revealed that a double helical vortex was formed in the host artery and flow recirculations near tow and heel regions were limited due to the secondary flow. Oscillating wall shear stress with significant secondary flow might be the flow dynamic reason of developing intimal hyperplasia or thrombosis.

• 대한치과의사협회지
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• 제23권1호통권188호
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• pp.73-81
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• 1985

In the assessment of patency of a small vessel anastomosis, micro-arteriography using dental X-ray and film was used as a method of testing the patency of arterial anastomoses in the rat. Micro-arteriography could lead to an objective evaluation of the patency in End-to-End and End-to Side anastomoses. The method used in this study is easily accessible for Oral and Maxillo-facial surgeon to practice the microvascular anastomosis, and requires materials available in every dental clinic.

• 대한의용생체공학회:의공학회지
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• 제24권2호
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• pp.113-119
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• 2003

본 연구에서는 end-to-end 문합시 변형된 직경의 불일치로 인하여 발생하게 되는 혈관질환을 방지하기 위하여 기계역학적 거동을 유한요소 법을 이용하여 해석한 결과를 나타내었다. 이 연구에서는 서로 다른 직경을 가지는 동맥과 인공혈관인 PTFE의 문합시 봉합으로 인한 예변형을 고려하였으며, 봉합된 문합부에 수축기혈압인 120mmHg(16.0KPa)을 작용시켜 혈관의 변형을 분석하였다. 변형 후 최종 문합부의 형상은 동맥과 PTFE의 초기 직경비(R$_{I}$)와 PTFE의 두께에 대하여 분석하였다. 그리고 동맥과 PTFE의 초기 직경비가 문합부에서 발생되는 응력에 어떠한 영향을 미치는지에 대하여 해석하여 다음과 같은 결과를 얻었다. 1. 혈관내막의 증식등을 고려하지 않고 봉합으로 인한 예변형과 수축기 혈압만을 고려할 경우 가장 이상적인 초기 직경비(R$_{I}$)는 1.073이다. 2. 상당응력과 원주방향응력은 초기 직경비(R$_{I}$) 증가에 따라 증가하며 모두 접합부에서 PTFE측으로 0.4mm 떨어진 지점에서 최대값이 발생하였다.

• 대한의용생체공학회:의공학회지
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• 제18권3호
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• pp.253-259
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• 1997

Von Mises stress and compliance distribution was evaluated using a finite element analysis on the anastomosis of an artery with length of 20mm(z direction, along the horizental artery), inner diameter of 4mm, thickness fo 0.5mm and a PTFE graft with length of 5.7mm, inner diameter of 2mm, thickness of 0.2mm when anastomotic angle was $45^{\circ}$ and inner pressure of 1330 dyne/mm2 was applied inside the 2 conduits. From the analysis results were obtained as follows. (1) Artery diameter increased in both horizontal x(along the length of artery) and vertical y(perpendicular to the length of artery)directions and the magnitude of that in x direction was bigger than that in y direction. (2) The compliance was maximum on the anastomosis, especially on that with acute angle. The reduction of compliance was observed from the anastomosis area to the either right or left end. (3) The equivalent stress was maximum on top in the y direction and minimum on the nodes apart $110^{\circ}$ in circumferential direction from the top. (4) The equivalent stress was maximum in t도 vicinity of anastomosis with acute angle along the longitudinal direction of the artery. This trend was also observed along the PTFE graft.

• Journal of Korean Neurosurgical Society
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• 제60권4호
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• pp.417-423
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• 2017

Objective : Repair of sensorial nerve defect is an important issue on peripheric nerve surgery. The aim of the present study was to determine the effects of sensory-motor nerve bridging on the denervated dermatomal area, in rats with sensory nerve defects, using a neural cell adhesion molecule (NCAM). Methods : We compared the efficacy of end-to-side (ETS) coaptation of the tibial nerve for sural nerve defect repair, in 32 Sprague-Dawley rats. Rats were assigned to 1 of 4 groups : group A was the sham operated group, group B rats had sural nerves sectioned and buried in neighboring muscles, group C experienced nerve sectioning and end-to-end (ETE) anastomosis, and group D had sural nerves sectioned and ETS anastomosis was performed using atibial nerve bridge. Neurological evaluation included the skin pinch test and histological evaluation was performed by assessing NCAM expression in nerve terminals. Results : Rats in the denervated group yielded negative results for the skin pinch tests, while animals in the surgical intervention groups (group C and D) demonstrated positive results. As predicted, there were no positively stained skin specimens in the denervated group (group B); however, the surgery groups demonstrated significant staining. NCAM expression was also significantly higher in the surgery groups. However, the mean NCAM values were not significantly different between group C and group D. Conclusion : Previous research indicates that ETE nerve repair is the gold standard for peripheral nerve defect repair. However, ETS repair is an effective alternative method in cases of sensorial nerve defect when ETE repair is not possible.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제25권1호
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• pp.62-68
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• 2023

The treatment of complicated anterior cerebral artery aneurysms remains challenging. Here, the authors describe a case of ruptured complicated A3 aneurysm, which was treated with trapping and in-situ bypass. A 47-year-old man presented to the emergency department with severe headache and vomiting. Computed tomography illustrated acute intracerebral hemorrhage in the right frontal lobe. Digital subtraction angiography (DSA) confirmed a ruptured fusiform A3 aneurysm with lobulation and a daughter sac. Trapping of the ruptured fusiform A3 aneurysm and distal end-to-side A4 anastomosis was performed. DSA on postoperative day 7 showed mild vasospasm to the afferent artery. However, 2 months later, DSA demonstrated that the antegrade flow through the anastomosis site had recovered. Thus, surgeons should be aware of the possibility of postsurgical vasospasm of anastomosed arteries, especially in cases of ruptured aneurysms.

• 대한의용생체공학회:의공학회지
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• 제13권4호
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• pp.339-352
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• 1992

A numerical simulation of the steady and pulsatile flow across the end-to-side anastomosis was performed In order to understand the role of flow dynamics in the preferential bevel opment of distal anastomotic intimal hyperplasla. The finite element technique was employed to solve two-dimensional unsteady pulsatile flow in that region. The results of the steady flow revealed that low shear stresses occur at the proximally occluded host artery and at the recirculation region in the Inner wall just distal to the toe region of the anastomosis. The nor- mal;zed wall shear rate was increased, as was the recirculation zone size in the host artery of the by-pass graft anastomosis, with increased anastomotic junction angle. In order to min imize the size of the low wall shear region which might result in the intimal hyperplasia in the by-pass graft anastomosis, a smaller anastomotic junction angle is recommended. The pulsatile flow simulation revealed flow that regions of low and ascillating mali shear do exist near the anastomosis as In the steady simulation. The shift of stagnation point depends on the pulsation of the flow. As the flow was accelerated at systole, the stagnation point moved downstream, disappered at early diastole and reappeared during late diastole. Low shear stress was also found along both walls of the occluded proximal artery. However, the diastolic flow behavior is quite different from the steady results. The vortex near the occluded artery moved downstream and inwardly during late systole, and disappeared during diastole. Recirculations proximal to the toe and heel regions were significant during diastole. Shear stress oscillation was found along the opposite wall. The results of the present study revealed that tow shear occurs at the proximally occluded host artery aud the recirculation region in the inner wall Just dlstal to the toe region of the anastomosis. The present study suggested that the regions of fluctuated wall shear stress wit flow separation is correlated with the preferential developing regions of anastomosis neointial fibrous hyperplasia.

• Journal of Chest Surgery
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• 제27권7호
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• pp.603-609
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• 1994

Esophageal atresia is a rare congenital anomaly and it usually associated with tracheo-esophgeal fistula and other congenital anomalies. The first report of esophageal atresia with tracheo-esophageal fistula was done by Thomas Gibson in 1696. In 1941, Haight performed the first successful primary anastomosis for esophageal atresia. These accomplishments opened the gateway for clinical studies that have resulted in reinforcements and improvement in the care of infants born with this anomaly. From January 1986 to April 1994, 14 cases of esophgeal atresia with tracheo-esophgeal fistula were diagnosed in Kyung Hee Uinv. Hospital. There were 9 male and 5 female infants. 12 infants were Gross classification type C and 2 infants were type A. The average body weight was 2.7$\pm$0.4kg and Waterson Category A contained 4 infants, B contained 3 infants and C contained 7 infants. Among these infants, 9 infants were underwent anastomosis procedures. We performed retropleural approach in 6 infants, transpleural approach in 2 infants and 1 infant was performed colon interposition through substernal space.By the method of anastomosis, end-to-side anastomosis was performed in 5 infants, end-to-end anastomosis in 3 infants and esophagocologastrostomy in 1 infant.The former 8 infants were Gross classification type C and the latter was type A. Among the type C infants, 6 infants were anastomosed with one layer interrupted suture and 2 infants with 2 layer interrupted suture. Post- operative death was in 1 infant and 8 infants were discharged with good result and have been in good condition.

• Archives of Reconstructive Microsurgery
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• 제1권1호
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• pp.51-55
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• 1992

Problems of composite tissue transfer commonly arise when a single indispensable recipient vessel receives the graft vssel, and the graft vessel must be sutured in end-to-side fashion so as not todisturb the vascularity of the recipient vessel. The triangular flap in the recipient vessel wall gives an intact endothelial surface when the flow of blood stream is presented and may reduce the chance of anastomosis. We selected mature Wistar rats weighing over 450 grams to compare the conventional longitudinal slit from the triangular flap in the recipient carotid artery over bloood pressure and blood flow when the donor carotid artery was anastomosed in end-to-side fashion. In 30 minutes after anastomosis, maximum blood pressure measured in the donor carotid arterial side when the recipient arterial wall was fasioned with the longitudinal slit was recorded 114 mmHg and with the triangular flap 100mmHg. Minimum blood pressure with the longitudinal slit was 98mmHg and with the triangular flap 88mmHg. The amount of blood collected for 30 seconds in the conventional longitudinal slit was 1.18mg and in the triangular flap 0.78mg. Histology study in 30 minutes, the conventional longitudinal slit demonstrated the more hemorrhagic features around the suture material compared to that of the triangular. flap and, in the 7th day, the conventional longitudinal slit demonstrated the more prominent granulomatous reactions and vascular proliferations around the suture material compared to that of the triangular flap.

• 대한의용생체공학회:의공학회지
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• 제15권3호
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• pp.253-258
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• 1994

Three-dimensional steady and pulsatile flows in an end-to-side anastomosis were investigated using a finite difference method in order to understand the flow dynamics in the preferential development of distal anastomotic intimal hyperplasia or thrombosis. Steady flow results revealed that a double helical vortex was formed in the host artery and flow recirculations near toe find heel regions were restricted due to the secondary flow. Oscillating wall shear stress with significant secondary flow might be flow dynamic reason of developing intimal hyperplasia or thrombosis near the anastomotic region.