대한의용생체공학회:의공학회지 (Journal of Biomedical Engineering Research)

  • 제13권4호
  • /
  • Pages.339-352
  • /
  • 1992
  • /
  • 1229-0807(pISSN)
  • /
  • 2288-9396(eISSN)
대한의용생체공학회 (The Korean Society of Medical and Biological Engineering)
권호 표지

Numerical Studies of Flow Across End-to-Side Distal Vascular Bypass Graft Anastomoses

  • Kim, Y.H. (School of Chemical Engineering) ;
  • Kim, J.H. (Mechanical Engineering Georgial Institute of Technology Atlanta) ;
  • Shin, J.W. (Mechanical Engineering Georgial Institute of Technology Atlanta)
  • 발행 : 1992.12.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A numerical simulation of the steady and pulsatile flow across the end-to-side anastomosis was performed In order to understand the role of flow dynamics in the preferential bevel opment of distal anastomotic intimal hyperplasla. The finite element technique was employed to solve two-dimensional unsteady pulsatile flow in that region. The results of the steady flow revealed that low shear stresses occur at the proximally occluded host artery and at the recirculation region in the Inner wall just distal to the toe region of the anastomosis. The nor- mal;zed wall shear rate was increased, as was the recirculation zone size in the host artery of the by-pass graft anastomosis, with increased anastomotic junction angle. In order to min imize the size of the low wall shear region which might result in the intimal hyperplasia in the by-pass graft anastomosis, a smaller anastomotic junction angle is recommended. The pulsatile flow simulation revealed flow that regions of low and ascillating mali shear do exist near the anastomosis as In the steady simulation. The shift of stagnation point depends on the pulsation of the flow. As the flow was accelerated at systole, the stagnation point moved downstream, disappered at early diastole and reappeared during late diastole. Low shear stress was also found along both walls of the occluded proximal artery. However, the diastolic flow behavior is quite different from the steady results. The vortex near the occluded artery moved downstream and inwardly during late systole, and disappeared during diastole. Recirculations proximal to the toe and heel regions were significant during diastole. Shear stress oscillation was found along the opposite wall. The results of the present study revealed that tow shear occurs at the proximally occluded host artery aud the recirculation region in the inner wall Just dlstal to the toe region of the anastomosis. The present study suggested that the regions of fluctuated wall shear stress wit flow separation is correlated with the preferential developing regions of anastomosis neointial fibrous hyperplasia.

키워드

참고문헌

  1. Am. J. Pathol v.118 Mechanisms of Arterial Graft Failure: I. Role of Cellular Proliferation in Early Healing of PTFE Prosthese Clowes,A.W.;Gown,A.M.
  2. Circulation Research v.22 Acute Vascular Endothelial Changes Associated with Increased Blood Velocity Gradients Fry,D.L.
  3. Proc. R. Soc. Lond. v.B117 Atheroma and Arterial Wall Shear: Observation, Correlation and Proposal of a Shear Dependent Mass Transfer Mechanism for Atherogenesis Caro,C.G.;Fitz-Gerald,J.M.;Schroter,R.C.
  4. Ann. Vas. Surg. v.1 Distal Anastomotic Intimal Hyperplasia: Histologic Character and Biogenesis Sottiuri,V.S.;Yao,J.S.T.;Batson,R.C.
  5. Circ. Res. v.42 Velocity Distribution and Intimal Proliferation in Autogenous Vein Grafts in Dogs Rittgers,S.E.;Karayannacos,P.E.;Guy,J.F.
  6. Surgery v.105 Mechanical Factors Predisposing to Intimal Hyperplasia and Medial Thickening in Autogeneous Vein Grafts Dobrin,P.B.;Littooy,F.N.;Endean,E.D.
  7. Archieves of Surgery v.114 Boundary Layer Separation in Models of Side-to-end Anastomosis Logerfo,F.W.;Soncrant,T.;Teel,T.;Dewey,C.F.
  8. J. Biomech. Eng. The Effect of Angle and Flow Rate upon Hemodynamics in Distal Vascular Graft Anastomoses: An In Vitro Model Study Keynton,R.S.;Shu,M.C.S.;Rittgers,S.E.
  9. Surgery Forum: Cong. Am. Coll. Sourg. Quantitative Inverse Correlation of Wall Shear Stress with Experimental Intimal Thickening Bassiouny,H.S.;Leiber,B.B.
  10. 35th ACEMB Flow Studies at Arterial Anastomoses Bharadvai,B.K.;Daddaria,D.M.
  11. Ph. D. Dissertation, University of Iowa Flow Dynamics in the Vicinity of End-to-end Anastomosis Kim,Y.H.
  12. Submitted to Biorheology Steady Flow Analysis in the Vicinity of an End-to-end Anastomosis Kim,Y.H.;Chandran,K.B.
  13. Archieves of Surgery v.115 Flow Disturbance at the Distal End-to-side Anastomosis Crawford,H.M.;Quist,W.C.;Serrallach,E.;Valeri,C.R.;Logerfo,F.W.
  14. J. Biomech v.19 Simulation of Coronary Artery Revascuarization Watts,K.C.;Marble,A.E.;Sarwal,S.N.;Kinley,C.E.;Watton,J.;Mason,M.A.
  15. J. Vasc. Surg. v.12 Steady and Pulsatile Flow studies in an End-to-side Arterial Anastomosis Model Ojha,M.;Ethier,C.R.;Johnston,K.W.;Cobbold,R.S.C.
  16. Third U.S.A.-China-Japan Conference on Biomechanics Exercise Flow Affects Hemodynamics of End-To-Side Vascular Graft Models Giddens,D.P.;Zarins,C.K.;Giddens,E.M.;Bassiuny,H.S.;Glagov,S.
  17. J. Vasc. Surg. v.5 Shear Stress Regulation of Artery Lumne Diameter in Experimental Atherogenesis Zarins,C.K.;Zatina,M.A.;Giddens,D.P.;Ku,D.N.;Glagov,S.
  18. J. Vasc. Surg. v.10 Optimal Graft Diameter: Effect of Wall Shear Stress on Vascular Healing Binns,R.L.;Ku,D.N.;Stewart,M.T.;Ansley,J.P.;Coyle,K.A.
  19. Circ. Res. v.66 Flow Patterns and Spatial Distribution of Atherrosclerotic Lesionsl in Human Coronary Arteries Asakura,T.;Karino,T.
  20. Microvasc. Res. v.17 Aggregation of Human Platelets in an Annular Vortex Distal to a Tubular Expansion Karino,T.;Goldsmith,H.L.
  21. Appl. Mech. Rev. v.43 Respons of Arteriec to Near Wall Fluid Dynamics Behavior Giddens,D.P.;Zarins,C.K.;Glagov,S.
  22. Arthe-rosclerosis v.5 Pulsatile Flow and Atherosclerosis in the Human Carotid BIfurcation: Positive Correlation Between Plaque Location and Low and Oscillating Shear Stress Ku,D.N.;Giddens,D.P.;Zarins,C.K.;Glagov,S.
  23. J. Vasc. Surg. v.2 Effect of Wall Shear Stress on Intimal Thickening of Arterially Traksplanted Autogenous Veins in Dogs Morinage,K.;Okadome,K.;Kuroki,M.;Miyazaki,T.;Muto,Y.;Inokuchi,K.
  24. Archs. Path. Lab. Med. v.112 Hemodynamics and Athero-scle-rosis: Insights and Perspectives Gained from Studies of Human Arteries Glagov,S.;Zarins,C.K.;Giddens,D.P.;Ku,D.N.