• Title/Summary/Keyword: End-to-end repair

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Surgical Repair of Type II Truncus Arteriosus Without a Extra-cardiac Conduct -A Case Report- (제2형 동맥간의 심장외 도관을 사용하지 않는 완전교정술 -1례 보고-)

  • 조은희
    • Journal of Chest Surgery
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    • v.28 no.6
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    • pp.619-622
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    • 1995
  • We report a successful surgical correction of type II truncus arteriosus without using a extra-cardiac conduit in an 2 month-old infant. The truncal root is transected, and the confluence of branch pulmonary arteries is brought anterior to the aorta by using Lecompte`s maneuver. The aorta is then reconstructed directly with an end-to-end anastomosis. The right ventricular outflow tract is reconstructed by anastomosing the posterior wall of the confluence directly to the upper part of the vertical right ventriculotomy. A monocusp ventricular outflow patch is then placed anteriorly to complete reconstruction of the right ventricular outflow tract. The patient had an uncomplicated postoperative course and was discharged on the 9th postoperative day.

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Estimation of Warranty Cost (품질하자보증비의 추정)

  • 최정호;이상용
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.20 no.43
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    • pp.357-364
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    • 1997
  • After the buyer purchases the product, the seller's role does not end. If the product fails to function properly before the end of the warranty period, the seller is responsible for its repair or replacement under the seller's warranty policy. There are two common types of warranty policies: the free replacement warranty and the rebate warranty. Under the free replacement warranty policy, replacement or repairs during the warranty period are provided by the seller free of charge to the buyer. Under the rebate warranty policy, a failed item is replaced by a new one or is repaired at a cost to the age of the failed item. The rebate warranty is most often used for items such as a battery or an automobile tire which wear out and must be replaced at failure. This paper proposes a easy way of estimating the warranty cost under the free replacement warranty policy assuming an exponential product failure function on repairable products.

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DNA damage repair is suppressed in porcine aged oocytes

  • Lin, Tao;Sun, Ling;Lee, Jae Eun;Kim, So Yeon;Jin, Dong Il
    • Journal of Animal Science and Technology
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    • v.63 no.5
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    • pp.984-997
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    • 2021
  • This study sought to evaluate DNA damage and repair in porcine postovulatory aged oocytes. The DNA damage response, which was assessed by H2A.X expression, increased in porcine aged oocytes over time. However, the aged oocytes exhibited a significant decrease in the expression of RAD51, which reflects the DNA damage repair capacity. Further experiments suggested that the DNA repair ability was suppressed by the downregulation of genes involved in the homologous recombination (HR) and nonhomologous end-joining (NHEJ) pathways. The expression levels of the cell cycle checkpoint genes, CHEK1 and CHEK2, were upregulated in porcine aged oocytes in response to induced DNA damage. Immunofluorescence results revealed that the expression level of H3K79me2 was significantly lower in porcine aged oocytes than in control oocytes. In addition, embryo quality was significantly reduced in aged oocytes, as assessed by measuring the cell proliferation capacity. Our results provide evidence that DNA damage is increased and the DNA repair ability is suppressed in porcine aged oocytes. These findings increase our understanding of the events that occur during postovulatory oocyte aging.

Intrasubstance Complete Rotator Cuff Tear with more than 1 cm of Remnant Attached to the Greater Tuberosity: 2 Case Reports (대결절에 1 cm 이상의 잔여 건이 부착된 회전근 개 실질 내 완전 파열 - 2례 보고 -)

  • Cho, Su-Hyun;Lee, Choon-Key;Cho, Hyung-Lae;Hwang, Tae-Hyok;Wang, Tae-Hyun
    • Journal of the Korean Arthroscopy Society
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    • v.13 no.1
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    • pp.77-81
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    • 2009
  • In patients with full-thickness tears of the rotator cuff, the tendon is usually detached from its bony insertion in the greater or lesser tuberosity. We experienced an unusual pattern of rotator cuff tear in two cases, in which complete rotator cuff tears occurred at the tendinous portion (i.e., intrasubstance tears) with more than a 1cm remnant attached to the greater tuberosity. Arthroscopic tendon-totendon repair was performed without remnant removal in both cases. Follow-up MRI at 6 months showed re-tear of the rotator cuff at the previous tear site in both of our patients. To prove the availability of arthroscopic tendon-to-tendon repair in such cases, a larger case follw-up and biomechanical studies are required.

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PATHWAYS AND GENES OF DNA DOUBLE-STRAND BREAK REPAIR ASSOCIATED WITH HEAD AND NECK CANCER (DNA 이중나선파손의 수복 과정과 이와 연관된 두경부암 발생 유전자)

  • Oh, Jung-Hwan;Lee, Deok-Won;Ryu, Dong-Mok
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.35 no.1
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    • pp.1-6
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    • 2009
  • DNA double-strand breaks (DSBs) occur commonly in the all living and in cycling cells. They constitute one of the most severe form of DNA damage, because they affect both strand of DNA. DSBs result in cell death or a genetic alterations including deletion, loss of heterozygosity, translocation, and chromosome loss. DSBs arise from endogenous sources like metabolic products and reactive oxygen, and also exogenous factors like ionizing radiation. Defective DNA DSBs can lead to toxicity and large scale sequence rearrangement that can cause cancer and promote premature aging. There are two major pathways for their repair: homologous recombination(HR) and non-homologous end-joining(NHEJ). The HR pathway is a known "error-free" repair mechanism, in which a homologous sister chromatid serves as a template. NHEJ, on the other hand, is a "error-prone" pathway, in which the two termini of the broken DNA molecule are used to form compatible ends that are directly ligated. This review aims to provide a fundamental understanding of how HR and NHEJ pathways operate, cause genome instability, and what kind of genes during the pathways are associated with head and neck cancer.

A Case of Chest Traumatic Bronchial Rupture, Manifested by Bronchial Web in Bronchoscopy (Web 양상으로 발현한 외상성 기관지 파열 1예)

  • Shim, Jae-Jeong;Han, Seung-Hwan;Lee, Jin-Goo;Cho, Jae-Yeun;In, Kwang-Ho;Kim, Kwang-Taek;Yoo, Sae-Hwa;Kang, Kyung-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.41 no.5
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    • pp.574-578
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    • 1994
  • The incidence of traumatic rupture of the tracheobronchial tree has been increased considerably with advent of widespread mechanization and high speed era. Rupture of the bronchus is an unusual result of nonpenetrating trauma to chest. Early diagnosis and primary repair not only restore normal lung function but also avoid difficulties and complications associated with delayed diagnosis and repair. These complications are pneumonia, atelectasis and lung abscess secondary to the bronchial obtruction. We experienced a case of partial rupture on left main bronchus caused by nonpenetrating blunt chest trauma with rib fractures 1 year ago. He was suffered from progressively developing dyspnea on exercise and treated as bronchial asthma at other hospital. Bronchoscopic finding was the narrowed lumen of left main bronchus at 1cm from carina by web-like membrane. We confirmed by bronchogram and repaired by end to end anastomosis, which is rare delayed finding in bronchial rupture without pulmonary complications. We report a case of nonpenetrating traumatic bronchial rupture, manifested by bronchial web in bronchoscopy.

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Spontaneous Achilles Tendon Rupture After Repeated Local Steroid Injention - A Case Report - (국소 스테로이드 반복 주사후 발생한 자발적 아킬레스건 파열 -증례 보고-)

  • Chung, Hyung-Jin;Choi, Jung-Yun
    • Journal of Korean Foot and Ankle Society
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    • v.8 no.2
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    • pp.218-220
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    • 2004
  • It is known that steroids increase the risk for tendon ruptures. Despite this local steroids are still used in the treatment of achilles tendinitis. 46-year-old women had occurred achilles tendon rupture after repeated local steroid injection. Intraoperatively, necrotic change were seen at both side of ruptured end. Like this, tendon rupture after repeated steroid injection often result in a large defect, which needed surgical repair. After debridement of ruptured end, tenorrhaphy with single Krackow method and plantaris tendon augmentation was done. The patient showed favorable result with return to range in a degree of activity levels.

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Reliability analysis of a complex system, attended by two repairmen with vacation under marked process with the application of copula

  • Tiwari, N.;Singh, S.B.;Ram, M.
    • International Journal of Reliability and Applications
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    • v.11 no.2
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    • pp.107-122
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    • 2010
  • This paper deals with the reliability analysis of a complex system, which consists of two subsystems A and B connected in series. Subsystem A has only one unit and B has two units $B_1$ and $B_2$. Marked process has been applied to model the complex system. Present reliability model incorporated two repairmen: supervisor and novice to repair the failed units. Supervisor is always there and the novice remains in vacation and is called for repair as per demand. The repair rates for supervisor and novice follow general and exponential distributions respectively and the failure time for both the subsystems follows exponential distribution. The model is analyzed under "Head of line repair discipline". By employing supplementary variable technique, Laplace transformation and Gumbel-Hougaard family of copula various transition state probabilities, reliability, availability and cost analysis have been obtained along with the steady state behaviour of the system. At the end some special cases of the system have been taken.

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A Crossover Node Discovery and Local Repair Mechanism for Reducing the Signaling Delay of Resource Reservation on HMIPv6 Networks (HMIPv6 네트워크에서 자원예약 시그널링 지연을 줄이기 위한 크로스오버 노드 발견 및 지역적 자원 갱신 방안)

  • Byun, Hae-Sun;Lee, Mee-Jeong
    • The KIPS Transactions:PartC
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    • v.15C no.1
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    • pp.37-44
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    • 2008
  • In order to minimize the signaling delay for a resource reservation on the new routing path after the handover of Mobile Node(MN) is completed, it is important to discover the crossover node where the old and new routing paths meet. With the 크로스오버 노드 being found, the signaling messages only need to be transferred on the changed part of the end-to-end path. The crossover node is generally discovered using the end-to-end Session ID(SID) of the established session between MN and Correspondent Node(CN). However, in the Hierarchical Mobile IPv6(HMIPv6) network, if the Mobile Anchor Point (MAP) reserves the resource by aggregate with the Home Agent(HA), the crossover node discovery cannot be performed in the general way since the aggregate SID that has established between the previous MAP and HA is different from the that of the current MAP and HA after MN's handover. In this paper, we propose a mechanism to discover the crossover node within the tunnel between the MAP and the HA in an HMIPv6 network, assuming that the Next Steps in Signaling(NSIS) is deployed for the resource reservation and the aggregate reservation is applied over the MAP and HA tunnel. The local repair required for the change of path is performed upon the crossover node discovery. The simulation results show that the proposed scheme reduces the signaling delay for the reservation and outperforms the existing scheme with respect to throughput during the handover.

Use of Cardiac Computed Tomography for Ventricular Volumetry in Late Postoperative Patients with Tetralogy of Fallot

  • Kim, Ho Jin;Mun, Da Na;Goo, Hyun Woo;Yun, Tae-Jin
    • Journal of Chest Surgery
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    • v.50 no.2
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    • pp.71-77
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    • 2017
  • Background: Cardiac computed tomography (CT) has emerged as an alternative to magnetic resonance imaging (MRI) for ventricular volumetry. However, the clinical use of cardiac CT requires external validation. Methods: Both cardiac CT and MRI were performed prior to pulmonary valve implantation (PVI) in 11 patients (median age, 19 years) who had undergone total correction of tetralogy of Fallot during infancy. The simplified contouring method (MRI) and semiautomatic 3-dimensional region-growing method (CT) were used to measure ventricular volumes. Results: All volumetric indices measured by CT and MRI generally correlated well with each other, except for the left ventricular end-systolic volume index (LV-ESVI), which showed the following correlations with the other indices: the right ventricular end-diastolic volume index (RV-EDVI) (r=0.88, p<0.001), the right ventricular end-systolic volume index (RV-ESVI) (r=0.84, p=0.001), the left ventricular end-diastolic volume index (LV-EDVI) (r=0.90, p=0.001), and the LV-ESVI (r=0.55, p=0.079). While the EDVIs measured by CT were significantly larger than those measured by MRI (median RV-EDVI: $197mL/m^2$ vs. $175mL/m^2$, p=0.008; median LV-EDVI: $94mL/m^2$ vs. $92mL/m^2$, p=0.026), no significant differences were found for the RV-ESVI or LV-ESVI. Conclusion: The EDVIs measured by cardiac CT were greater than those measured by MRI, whereas the ESVIs measured by CT and MRI were comparable. The volumetric characteristics of these 2 diagnostic modalities should be taken into account when indications for late PVI after tetralogy of Fallot repair are assessed.