• Journal of Sericultural and Entomological Science
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• v.45 no.2
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• pp.108-111
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• 2003

A infectious fungus (J131) recently isolated from artificial cultivation farms of Paecilomyces tenuipes is known to cause a great yield loss and deterioration of products. In this study, its occurrence and characterization were made. The isolate (J131) was identified as Paecilomyces farinosus (Holm ex S. F. Gray) Brown ＆ Smith. Colonies of the isolate on PDA grew moderately fast, attaining a diameter of 19mm within 14 days at 24${\pm}$1$^{\circ}C$. Vegetative hyphae are smooth-walled and hyaline. Conidiophores mainly arose from the submerged mycelium, usually measuring 1.3-1.5$\mu\textrm{m}$ wide and consisted of verticillate branches with whorls of 2 to 4 phialides. Phialides of 3.8-5.8${\times}$1.5-1.8 $\mu\textrm{m}$, with a swollen basal portion tapered into a distinct neck of about 0.6-0.8 $\mu\textrm{m}$ wide. Conidia arisen from the phialides, were ellipsoidal to fusiform, smooth-walled, hyaline, 1.8-2.4${\times}$1.1-1.4$\mu\textrm{m}$. .When silkworm larvae were injected with concentration of 1${\times}$10$\^$8/ conidia/$m\ell$ of infectious fungus J131, infection rate was 41.3％ and synnemata formation rate was 23.6％. Black spots were appeared on the surface of silkworm larvae in 5-9 days after injection. The surface of larvae was covered with hyphae which were gradually turned into yellow from white color during the incubation period of 3-4 days. 1 to several 4-6mm long synnemata of yellow or orange color were formed on the surface. The matured synnemata were ramified from its end and produced much conidia of white color.

• Nuclear Engineering and Technology
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• v.53 no.10
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• pp.3367-3378
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• 2021

The design phase and safety assessment of Generation IV liquid metal-cooled fast reactors calls for the improvement of fuel pin performance codes, in particular the enhancement of their predictive capabilities towards uranium-plutonium mixed oxide fuels and stainless-steel cladding under irradiation in fast reactor environments. To this end, the current capabilities of fuel performance codes must be critically assessed against experimental data from available irradiation experiments. This work is devoted to the assessment of three European fuel performance codes, namely GERMINAL, MACROS and TRANSURANUS, against the irradiation of two fuel pins selected from the SUPERFACT-1 experimental campaign. The pins are characterized by a low enrichment (~ 2 wt.%) of minor actinides (neptunium and americium) in the fuel, and by plutonium content and cladding material in line with design choices envisaged for liquid metal-cooled Generation IV reactor fuels. The predictions of the codes are compared to several experimental measurements, allowing the identification of the current code capabilities in predicting fuel restructuring, cladding deformation, redistribution of actinides and volatile fission products. The integral assessment against experimental data is complemented by a code-to-code benchmark focused on the evolution of quantities of engineering interest over time. The benchmark analysis points out the differences in the code predictions of fuel central temperature, fuel-cladding gap width, cladding outer radius, pin internal pressure and fission gas release and suggests potential modelling development paths towards an improved description of the fuel pin behaviour in fast reactor irradiation conditions.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.4
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• pp.353-362
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• 2021

Cancer is a global health problem. There are diverse types of cancers, but there are several common pathways which lead to the development of cancer. Changes in gene expression might be the most common similarity found in almost all cancers. An understanding of the underlying changes in gene expression during cancer progression could lay a valuable foundation for the development of cancer therapeutics and even cancer vaccines. In this study, a well-known carcinogen, N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), was employed to induce changes in gene expression in normal stomach cells. MNNG is known to cause cancer by inducing damage to DNA in MNNG-treated mammalian cells and animals fed with this carcinogen. An analysis was performed by comparing the differentially expressed genes (DEGs) caused by MNNG treatment with DEGs in stomach cancer cell lines. To this end, methods of analysis for functional categorization and protein-protein interaction networks, such as gene ontology (GO), the database for annotation, visualization, and integrated discovery (DAVID), Kyoto encyclopedia of genes and genomics (KEGG) and search tool for the retrieval of interacting genes/proteins (STRING), were used. As a result of these analyses, MNNG-regulated specific genes and interaction networks of their protein products that contributed to stomach cancer were identified.

• The Journal of the Korea Contents Association
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• v.19 no.8
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• pp.205-213
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• 2019

A number of small and medium design companies in Korea are making efforts to develop distinguished products with an aim to survive and prosper. However, it is quite difficult to succeed due to insufficient experience in product planning and the challenges in applying known methodologies, which are based on a large amount of data presented as best practices in designing process, in the actual small and medium enterprise operations. To this end, this study suggested the usefulness of the user participation process as the methodology for small and medium design companies and chose the user FGD method implemented by Company P which is a small design company as an empirical case study. The following are the processes used in the case study; First, the problems of existing baby bath were derived through user FGD. Second, opinions were collected from various classes of users through in-depth interviews. Third, the ideas derived were analyzed with the KJ method and grouped based on similar elements, through which six design directions and detailed design concepts covering size, material, safety, purchase factors of existing product, direction of improvement, additional elements were derived. Through the case study, this study verified that the FGD method of Company P could improve the practical verification, integration and promptness of the product planning process in small and medium enterprises. This is valuable as a realistic process that small and medium enterprises with limited capital and manpower may adopt.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.6
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• pp.113-125
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• 2019

This research aims to understand the common psychological features of consumer. And master the direction of the development of the network novels derivation by analysis the TV plays adapted from network novels in China's IP industry. To this end, This research determine to analyzed consumer adoption attitude the Behavior Intention of derivative products. The date were collected from 612 Chinese people, from October 15 to October 22 2018. Statistical analysis were through SPSS 21 after data coding and data cleanings process. This research performed frequency analysis exploratory factor analysis, Independent sample t-test, one-way ANOVA, post-analysis Duncan test, correlation analysis and mass regression analysis. The research results are as follows. Firstly, the characteristics(topicality, empathy and interest) of network novel TV play positively related role in the adoption attitudes(cognitive attitude and emotional attitude) of derivatives commodities. At the same time, identity has a more positively related influence than topicality and interest. Secondly, all the characteristics of network novels consisting of topicality, identity and interest play positive related roles in the behavioral intentions of derivative commodities. Thirdly, emotional attitude plays a more positively related role in purchasing intention and recommendation intention compared with cognitive attitude. It is hoped that the research results can play a fundamental role in the production and development of network novels derivatives.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.2
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• pp.151-159
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• 2019

Ergothioneine has been known as an excellent antioxidant and a cellular protector against oxidative damage in vivo. In the present study, ergothioneine was demonstrated to possess antioxidant and anti-glycation activities. The radical scavenging activity of ergothioneine enhanced the viability of human dermal fibroblasts (HDFs) exposed to ultraviolet (UV) light. The UVA irradiation increased the proportion of senescence-associated ${\beta}$-galactosidase (SA-${\beta}$-gal) positive cells in comparison with the normal control group. The treatment of UVA-irradiated HDFs with ergothioneine decreased the level of SA-b-gal (by approximately 45% at an ergothioneine concentration of $400{\mu}M$) compared with the UVA-irradiated HDFs. We also found that ergothioneine inhibited production of glyceraldehyde-derived advanced glycation endproducts (AGEs) in a concentration-dependent manner. The ergothioneine educed carboxymethyl-lysine (CML) expression in comparison to the glyoxal treatment. In addition, in the Western blot analysis, treatment of glyoxal-stimulated HDFs with ergothioneine resulted in a dose-dependent decrease in the expression level of the receptor for AGE (RAGE). These results suggest that ergothioneine may have potent anti-aging effects and could be used as a cosmetic material against cellular accumulation of AGEs.

• Korean Journal of Remote Sensing
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• v.34 no.6_1
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• pp.997-1007
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• 2018

Drought monitoring is the important system for disasters by climate change. To perform this, it is necessary to measure the precipitation based on satellite rainfall estimation. The data developed in this study provides two kinds of satellite data (raw satellite data and bias-corrected satellite data). The spatial resolution of satellite data is 10 km and the temporal resolution is 1 day. South Korea was selected as the target area, and the original satellite data was constructed, and the bias-correction method was validated. The raw satellite data was constructed using TRMM TMPA and GPM IMERG products. The GRA-IDW was selected for bias-correction method. The correlation coefficient of 0.775 between 1998 and 2017 is relatively high, and TRMM TMPA and GPM IMERG 10 km daily rainfall correlation coefficients are 0.776 and 0.753, respectively. The BIAS values were found to overestimate the raw satellite data over observed data. By using the technique developed in this study, it is possible to provide reliable drought monitoring to Korean peninsula watershed. It is also a basic data for overseas projects including the un-gaged regions. It is expected that reliable gridded data for end users of drought management.

• Food Science and Industry
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• v.52 no.3
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• pp.272-286
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• 2019

Cheesemaking is believed to have been first practiced in prehistoric times, about 9,500 years ago, in the area around the Fertile Crescent of Mesopotamia and they left legacy in the name of cheese. Father Chi Chong-Hwan(Didier Serstevens) started for his provost in Imsil Catholic church in 1964. In 1968, cheese was first produced Camembert in Korea by Father Chi Chong-hwan, and then made Mozzarella in 1970, Cheddar in 1972. Father Chi lay the foundation of a cheese industry in Korea. The processed cheese market was highly grown after putting on the market of sliced cheese in the late 1980s, and the various products that complied with wellbeing trends such as organic and high functional cheese produced in the 2000s. The natural cheese opens up a new domestic market after producing Camembert and Brie cheese in the end of 2004. At present, major trends in cheese are authenticity, bold flavor, snack sophistication and tradition. Mozzarella, Parmesan, Cheddar, Provolone, Feta cheese still top in foodservice. In Korea, production of natural cheese is decreasing by the influence of the imported cheese. Production of processed cheese is increasing and total consumption of cheese is also increasing year by year.

• Molecules and Cells
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• v.42 no.9
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• pp.672-685
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• 2019

Currently, liver transplantation is the only available remedy for patients with end-stage liver disease. Conservation of transplanted liver graft is the most important issue as it directly related to patient survival. Carbonyl reductase 1 (CBR1) protects cells against oxidative stress and cell death by inactivating cellular membrane-derived lipid aldehydes. Ischemia-reperfusion (I/R) injury during living-donor liver transplantation is known to form reactive oxygen species. Thus, the objective of this study was to investigate whether CBR1 transcription might be increased during liver I/R injury and whether such increase might protect liver against I/R injury. Our results revealed that transcription factor Nrf2 could induce CBR1 transcription in liver of mice during I/R. Pre-treatment with sulforaphane, an activator of Nrf2, increased CBR1 expression, decreased liver enzymes such as aspartate aminotransferase and alanine transaminase, and reduced I/R-related pathological changes. Using oxygen-glucose deprivation and recovery model of human normal liver cell line, it was found that oxidative stress markers and lipid peroxidation products were significantly lowered in cells overexpressing CBR1. Conversely, CBR1 knockdown cells expressed elevated levels of oxidative stress proteins compared to the parental cell line. We also observed that Nrf2 and CBR1 were overexpressed during liver transplantation in clinical samples. These results suggest that CBR1 expression during liver I/R injury is regulated by transcription factor Nrf2. In addition, CBR1 can reduce free radicals and prevent lipid peroxidation. Taken together, CBR1 induction might be a therapeutic strategy for relieving liver I/R injury during liver transplantation.

• Journal of the Korea Convergence Society
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• v.10 no.10
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• pp.153-160
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• 2019

In this study, The purpose of this study is to analyze how the rating scale and review contents attributes of social network-based services and products affect consumer purchasing patterns. information provided by screening the main factors. These analyzes are closely and quickly integrated between individuals and businesses, and enable to analyze the transaction that the impact of changing consumers on consumption and purchasing through the usefulness and a priori estimates of reviews and ratings at this time when networks and smart technologies are involved in a wide range of consumer activities. For this study, hierarchical analysis (AHP) and delphi (Delphi) methods applied to classify the high end variables into usefulness, technicality and value, Each subvariable was grouped into three factors and analyzed for importance through evaluation weights. As a result, we could analyze the importance of durability, usefulness, technological innovation, and cost and quality of value. Therefore, this study is expected to provide supplementary and additional useful information to consumers and companies participating in economic activities in various ways by simultaneously analyzing the review score and the reliability of posting information provided by verifying the main factors.