• Archives of Pharmacal Research
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• v.19 no.6
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• pp.581-585
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• 1996

A new formal total synthesis of (+)-6-oxo-3, 4, 4a, 5-tetrahydro-3-hydroxy-2, 2-dimenthylnaphtho-1, 2-pyran (1) which has been known to have bactericidal, bacteriostatic, fungicidal, fungistatic activities against Staphylococcus aureus and other microorganism, is described. The key reaction involves enantioselective prenylation of .alpha.-tetralone via chiral lithioenamine.

• Bulletin of the Korean Chemical Society
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• v.34 no.7
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• pp.1949-1950
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• 2013

• Proceedings of the PSK Conference
• /
• 2002.04a
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• pp.50-54
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• 2002

• Bulletin of the Korean Chemical Society
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• v.11 no.1
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• pp.81-82
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• 1990

• Bulletin of the Korean Chemical Society
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• v.18 no.2
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• pp.137-139
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• 1997

• Bulletin of the Korean Chemical Society
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• v.19 no.3
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• pp.386-390
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• 1998

• Bulletin of the Korean Chemical Society
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• v.16 no.12
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• pp.1138-1139
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• 1995

• Bulletin of the Korean Chemical Society
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• v.16 no.2
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• pp.191-193
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• 1995

• Journal of Life Science
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• v.15 no.5 s.72
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• pp.779-782
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• 2005

Cell-free expression is a powerful tool for rapid protein analysis, enabling an efficient identification of gene without cumbersome procedure of transformation and cell culture. Epoxide hydrolase (EH) gene of Rhodotorula glutinis was simply amplified by PCR, and the resultant gene was expressed in vitro using a coupled Transcription/translation system. The cell-free expressed EH protein mixture exhibited the enantioselective hydrolysis activity toward (R)-styrene oxide, representing that cell-free protein synthesis system can be used for the rapid expression of an enantioselective enzyme for an efficient identification of the chiral activity.

• Advances in materials Research
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• v.2 no.1
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• pp.51-64
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• 2013

Enantioselective macromer of trimesic acid was prepared using S(-) menthol with trimesoyl chloride on polyimide (PI) ultrafiltration membrane. The chemical composition of macromer as well as polyimide ultrafiltration membrane was determined by ATR-FTIR Spectroscopy. The optical resolution of chiral alcohols was performed in pressure driven process. The effect of monomer solutions concentration, effect of air-drying time of S(-) menthol solution, effect of reaction time, effect of operating pressure, effect of feed concentration of racemate on the performance of macromer was studied. The synthesised material exhibits separation of chiral alcohols (menthol ~23% and sobrelol ~21%).