Gardenia jasminoides (G. jasminoides) is traditionally used to treat insomnia, jaundice, emotional disorders, hepatic disease, and inflammatory disease. Previously, we found that geniposide and the water extract of G. jasminoides increased $Cl^-$ influx in neuroblastoma. Here we examined the sychopharmacological activities of G. jasminoides and its constituents. G. jasminoides extract was orally administered at 100 and 200 mg/kg, and genipin and geniposide were intraperitoneally injected at 2, 10, and 20 mg/kg. G. jasminoides extract (200 mg/kg) significantly decreased total open field activity but increased rearing activity in the center of the open field, suggesting an increase in exploratory activity. Genipin and geniposide did not change open field activity, but geniposide (20 mg/kg) increased rearing activity in the central area. The extract (200 mg/kg) significantly decreased rotarod and wire-balancing activity, but genipin and geniposide did not. No compounds influenced thiopental-induced sleeping or electroshock-induced seizures. The extract (200 mg/kg) significantly increased staying time in the open arms of the elevated plus maze and the entry ratio into the open arms, and geniposide (20 mg/kg) also increased open arm entry. Electroshock stress decreased open arm activity, but the extract and geniposide (20 mg/kg) significantly reversed that effect. This results indicate that G. jasminoides extract and geniposide alleviated anxiety with greater efficacy in stressed animals than normal animals.
The purpose of this study is to provide a basis for nursing intervention strategies to promote quality of life in cancer patients. Therefore the study is designed to evaluate the effectiveness of perceived health status, self-esteem, health locus of control, self-efficacy, perceived susceptibility /severity, health promoting behaviors, and hope for quality of life. The sample was composed of 164 stomach cancer patients who visited outpatient clinics at a university hospital in Seoul. The following instruments were used in the study after some adaptation : Lawstone and others' Health Self-rating Scale, Rosenberg's Self-esteem Scale, Wallston and others 'Multidimensional Health Locus of Control Scale, Sherer & Maddux's Self-efficacy Scale, Moon's Health Beliefs Scale, Walker and others' Health Promoting Lifestyle Profile, Nowotney's Hope scale and Noh's Quality of Life Scale. Data were analyzed using a SAS program for Pearson correlation coefficients, descriptive correlational statistics and stepwise multiple regression. The results are as follows : 1. The scores on the quality of life scale ranged from 115 to 243 with a mean of 177.84(SD : 25.35). The mean scores(range 1-5) on the different dimensions were : emotional state 3.37 : economic life 3.47 : physical state & function 3.52 : self-esteem 3.66 : relationship with neighbors 3.37 ; family relationships 3.80. 2. There was a significant correlation between all the predictive variables and the quality of life (r=.20-.65, p<.01). 3. Stepwise multiple regression analysis showed that : 1) Self-esteem was the main predictor of quality of life and accounted for 46.9% of the variance in quality of life. 2) Perceived health status, hope and perceived susceptibility/severity accounted for 11.8%, 8.3%, 1.5% of the variance in quality of life, respectively. 3) Self-esteem, perceived health status, hope & perceived susceptibility /severity combined accounted for 68.5% of the variance in quality of life. In conclusion, self-esteem, perceived health status, hope and perceived susceptibility / severity were identified as important variables in the quality of life of cancer patients.
Journal of the Korean Society of Physical Medicine
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v.11
no.2
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pp.17-24
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2016
PURPOSE: This study aimed to evaluate the effects of health-promoting behaviors on the subjective well-being of a physical therapist. METHODS: Survey data were collected from 247 physical therapists in Daejeon city. The baseline for health-promoting behaviors was determined using Health Promoting Lifestyle Profile (HPLP), subjective well-being was determined using Positive Affect and Negative Affect Schedule (PANAS), quality of life was measured using the SF-36 (Short-Form 36), and pain level was determined using the Quadruple Visual Analogue Scale (QVAS). Health-promoting behaviors and related factors were analyzed using an average comparative analysis (t-test), and the factors relevant to subjective well-being and health-promoting behaviors were evaluated using correlation analysis (Pearson's correlation coefficient). Factors affecting health-promoting behaviors were evaluated using stepwise multiple regression analysis (stepwise multiple regression). RESULTS: The mean score for health-promoting behavior was 3.73, with emotional support having the highest score (3.90) and regular meals having the lowest score (3.16 points; p<0.01). Health-promoting behavior was significantly correlated with positive emotions and negative emotions are subjective well-being, negative emotions and pain were noted (p<0.01). Health-promoting behaviors showed a significant correlation with quality of life (r=0.04), positive emotions (r=0.21; p<0.01), negative emotions (r=0.16; p<0.05), and pain level (r=0.016). The results of this study showed that health-promoting behaviors are significant predictors of subjective well-being in physical therapists (p<0.01). CONCLUSION: Physical therapists have to maintain their health by avoiding infections. Regular exercise is the most important factor among all health-promoting behaviors.
Sohn, Jin-Hun;Estate Sokhadze;Lee, Kyug-Hwa;Imgap Yi
Proceedings of the Korean Society for Emotion and Sensibility Conference
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2000.04a
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pp.370-379
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2000
Autonomic responses were analyzed in 323 college students exposed to visual stimulation with Korean Affective Picture System (KAPS). Cardiac, vascular and electrodermal variables were recorded during 30 sec of viewing affective pictures. The same slides intended to elicit basic emotions (fear, anger, surprise, disgust, sadness, happiness) were presented to subjects in 2 trials with different experimental context. The first time slides were shown without any instructions (passive viewing), while during the second with instruction to exert efforts to magnify experienced emotion induced by pictures (active viewing). The aim of the study was to differentiate autonomic manifestations of emotions elicited by KAPS stimulation and to identify the role of instructed emotional engagement on physiological response profiles. The obtained results demonstrated reproducibility of responses in both trials with different contexts. Pairwise comparison of physiological responses in emotion conditions revealed the most pronounced differentiation for "ear-anger" and "fear-sadness" pairs (in electrodermal and HR variability parameters). "Fear-surprise" pair was also well differentiable. The typical response profile for all emotions included HR acceleration (except happiness and surprise), an increase of electrodermal activity, and a decrease of pulse volume. Higher cardiovascular and electrodermal reactivity to fear observed in this study, e.g., as compared to data with IAPS as stimuli, can be explained by cultural relevance and higher effectiveness of KAPS as stimuli, can be explained by cultural relevance and higher effectiveness of KAPS in producing certain emotions such as fear in Koreans.
Autonomic and EEG responses were analyzed in 32 college students exposed to visual stimulation with Korean Affective Picture System (KAPS) and 36 students exposed to the International Affective Picture System (IAPS). Cardiac, electrodermal, and electrocortical measures were recorded during 30 sec of viewing affective pictures. The slides intended to elicit basic emotions (fear, anger, surprise, disgust, and sadness) were presented to subjects via Kodak slide-projector. The aim of the study was to differentiate autonomic and EEG responses associated with the same negative valence emotions elicited by KAPS and IAPS stimulation and to identify the influence of cultural relevance on physiological reactivity. The analysis of obtained results revealed significant differences in physiological responsiveness to emotionally negative valence slides from KAPS and IAPS. The typical response profile for all emotions elicited by the KAPS included HR acceleration (except surprise), and increase of electrodermal activity, slow and fast alpha blocking and fast beta power increase in EEG, which was not associated with significant asymmetry (except fast alpha in sadness). Stimulation with the IAPS evoked HR deceleration, specific electrodermal responses with relatively high tonic electrodermal activation, alpha-blocking and fast beta increase, and was accompanied also by theta power increase and marked frontal asymmetry (e.g., fast beta, theta asymmetries in sadness, fast alpha in fear). Physiological responses to fear and anger-eliciting slides from the IAPS were significantly less profound and were accompanied by autonomic and EEG changes more typical for attention rather than negative affect. Higher cardiovascular and electrodermal reactivity to fear emotion observed in the KAPS, e.g., as compared to data with the IAPS as stimuli, can be explained by cultural relevance and higher effectiveness of the KAPS in producing certain emotions such as fear in Koreans.
Park, Young-Joo;Viau, Paula A.;Jung, Chun-Hee;Yoon, Ji-Won
Journal of Home Health Care Nursing
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v.8
no.1
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pp.85-95
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2001
This study was performed to explore the family support. the quality of marital relationship, and health promoting behaviors of the mature gravidas. and to validate the relationship between them. From November, 1999 to June. 2000. mature gravidas older than 35(N=82) were recruited from K University Hospital located in Seoul and Kyungki Province. Korea. Data was collected using a self-rating method and semi-structured interview. The questionnaires were: Perceived Social Support from Family developed by Procidano & Heller (1983). Quality of Marital Index by Norton (1983). and Health Promoting Life-style Profile by Walker, Sechrist, & Pender (1987), Interviews were conducted using the interview guide with open-ended questions related to health concerns and health promoting behaviors. Data was analyzed using a pc-SAS program for quantitative data. The levels of the perceived family support and the quality of marital relationship were relatively high. The relationship between perceived family support and quality of marital relationship, and health promoting life-style behaviors was statistically significant. Six themes emerged as primary concerns for the mature gravidas during childbearing: 'Concerns related to the fetal wellbeing', 'Concerns related to fetal education', 'Concerns related to the maternal physical health', 'Concerns related to the maternal emotional health', 'Concerns related to safe delivery' and 'Concerns related to child-rearing'. Nursing implications for practice include expanding prenatal assessment inventories to address the concerns and support system of mature gravidas.
The purpose of this study was to compare the difference between the adaptive and internalizing/externalizing maladaptive behaviors of the sensory processing problemtic group classified from non-disabled preschoolers and to confirms the effects of sensory processing sub-factors on adaptive and maladaptive behaviors. This study participated in 335, 3-6 years typical preschoolers, carried out Short sensory profile, Vineland-II adaptive behavior scales. The study result in the sensory processing showed a significant positive correlation with the adaptive behavior, and a significant negative correlations were found in the internalizing/externalizing maladaptive behaviors. In the t-test, the problemtic group had lower adaptive behavior scores than the typical group. This study confirmed that atypical sensory processing affected not only adaptive behavior, but also internalizing/externalizing maladaptive problems, that sensory processing difficulties were more related to emotional and behavioral issues.
Kim, Eun Sook;Jeong, Mi Jo;Kim, Sue;Shin, Hyun-A;Lee, Hyang Kyu;Shin, Kayoung;Han, Jee Hee
Women's Health Nursing
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v.20
no.1
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pp.14-28
/
2014
Purpose: This study was to identify relationships of maternal psychosocial factors including mother's mood state, childcare stress, social support and sleep satisfaction with breastfeeding adaptation and immune substances in breast milk, especially secretory immunoglobulin A (sIgA) and transforming growth factor-beta 2 (TGF-${\beta}2$). Methods: Data were collected from 84 mothers who delivered full-term infants by natural childbirth. Structured questionnaires and breast milk were collected at 2~4 days and 6 weeks postpartum. Data were analyzed using descriptive statistics, Pearson's correlation, multiple linear regression, and generalized estimating equation (GEE). Results: Scores for the breastfeeding adaptation scale were significantly related with child care stress, mood state and social support. Mother's anger was positively correlated with the level of sIgA in colostrum (p<.01). Immune substances of breastmilk was significantly influenced by time for milk collection (p<.001) and the type of breastfeeding (sIgA, p<.001, TGF-${\beta}2$, p=.003). Regression analysis showed that breastfeeding adaptation could be explained 59.1% by the type of breastfeeding, childcare stress, the Profile of Mood States, emotional support and sleep quality (F=16.67, p<.001). Conclusion: The findings from this study provide important concepts of breastfeeding adaptation program and explanation of psychosocial factors by immune substances in breast milk. Future research, specially, bio-maker research on breast milk should focus on the ways to improve breastfeeding adaptation.
Stytsyuk, Rita Yurievna;Panova, Alexandra Georgievna;Zenin, Sergey;Kvon, Daniil Andreevich;Gorokhova, Anna Evgenievna;Ulyanishchev, Pavel Viktorovich
International Journal of Computer Science & Network Security
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v.22
no.6
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pp.39-44
/
2022
The advent, course, and possible consequences of the COVID-19 pandemic are now the focus of global attention. From whichever side the geopolitical centers of influence might view it, the problem of the coronavirus concerns all world leaders and the representatives of all branches of science, especially physicians, economists, and politicians - virtually the entire population of the planet. The uniqueness of the COVID-19 phenomenon lies in the uncertainty of the problem itself, the peculiarities and specifics of the course of the biological processes in modern conditions, as well as the sharp confrontation of the main political players on the world stage. Based on an analysis of scientific research, the article describes the profile of the emotional concept of "anxiety" in Russian linguoculture. Through monitoring the headlines of Russian media reports in the "COVID-19" section of Google News and Mail News news aggregators dated August 4-6, 2021, the study establishes the quantitative and qualitative characteristics of the alarm-generating news products on coronavirus in the Russian segment of the Internet and interprets the specifics of media information about COVID-19. The level of mass media criticism in Russia is determined through a phone survey. It is concluded that coronavirus reports in online media conceptualize anxiety about the SARS virus and the COVID-19 disease as a complex cognitive structure. The media abuse the trick of "magic numbers" and emotionally expressive words in news headlines, which are perceived by mass information consumers first and typically uncritically.
Kim, Eui-Joong;Lee, Sang-Ick;Jeong, Do-Un;Shin, Min-Sup;Yoon, In-Young
Sleep Medicine and Psychophysiology
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v.10
no.1
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pp.39-51
/
2003
Objectives: The Profile of Mood States (POMS) has been used broadly and frequently in various medical studies with various subjects. For the development and application of the Korean edition of POMS, called K-POMS, we translated POMS into Korean and then evaluated the reliability and validity of K-POMS. Methods: The subjects were 161 male students with a mean age of 18.1 years (15-30) and 244 female students with a mean age of 16.6 years (14-23). They were requested to perform K-POMS and SCL-90-R (Korean version) at the same time. Means, reliability coefficients, and test-retest correlations of K-POMS were calculated. Content validities, correlations with SCL-90-R, and discrimination validities in comparison with 76 depressive patients were obtained, and factor analyses were carried out. Results: Mean scores of Total Mood Disturbance (TMD) and some subscales (T, F, C, V factor) showed a significant difference between male and female students. The internal consistency coefficient ($\alpha$) of the total 65 items was 0.93, and ranged from 0.67 to 0.90 for subscales. Test-retest correlations of 43 subjects ranged from 0.27 to 0.63. Seven psychiatrists rated the properness of the content of each item as more than moderate degree (mean scale points=2.66, in the range of 0 to 4). Every subscale of KPOMS exhibited significant correlation with the matching subscale of SCL-90-R. Mean scores of K-POMS of the total 405 subjects were significantly different from those of the 76 depressive subjects after age correction. Six factors were extracted, accounting for 51.2% of total variance. Factor 6 consisted of 6 items which came from various subscales of POMS and represented "uncertainty and helplessness," which may be somewhat different to depression or sadness proper. Conclusion: The validity and reliability of K-POMS could be confirmed. The significant difference in K-POMS scores between depressive subjects and normal subjects suggests that K-POMS can be used clinically for the evaluation and screening of depression. The main structure of K-POMS is very similar to that of POMS, except the Confusion-Bewilderment factor which shows weak factor consistency in K-POMS. This may reflect some emotional characteristic of Koreans such as an undifferentiated aspect of cognitive efficiency. The sixth factor newly extracted from K-POMS also may be indicative of an unique emotional aspect of young Koreans.
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