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Role of Household Exposure, Dietary Habits and Glutathione S-Transferases M1, T1 Polymorphisms in Susceptibility to Lung Cancer among Women in Mizoram India

  • Phukan, Rup Kumar;Saikia, Bhaskar Jyoti;Borah, Prasanta Kumar;Zomawia, Eric;Sekhon, Gaganpreet Singh;Mahanta, Jagadish
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.7
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    • pp.3253-3260
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    • 2014
  • Background: A case-control study was conducted to evaluate the effect of household exposure, dietary habits, smoking and Glutathione S-Transferases M1, T1 polymorphisms on lung cancer among women in Mizoram, India. Materials and Methods: We selected 230 newly diagnosed primary lung cases and 460 controls from women in Mizoram. Multivariate logistic regression analysis was performed to estimate adjusted odds ratio (OR). Results: Exposure of cooking oil fumes (p<0.003), wood as heating source for cooking (p=0.004), kitchen inside living room (p=0.001), improper ventilated house (p=0.003), roasting of soda in kitchen (p=0.001), current smokers of tobacco (p=0.043), intake of smoked fish (p=0.006), smoked meat (p=0.001), Soda (p<0.001) and GSTM1 null genotype (p=0.003) were significantly associated with increased risk of lung cancer among women in Mizoram. Significantly protective effect was observed for intake of bamboo shoots (p=<0.001) and egg (p<0.001). A clear increase in dose response gradient was observed for total cooking dish years. Risk for lung cancer tends to increase with collegial effect of indoor environmental sources (p=0.022). Significant correlation was also observed for interaction of GST polymorphisms with some of dietary habits. Conclusions: We confirmed the important role of exposure of cooking oil emission and wood smoke, intake of smoked meat, smoked fish and soda (an alkali preparation used as food additives in Mizoram) and tobacco consumption for increase risk of lung cancer among Women in Mizoram.

Characteristics of Non-premixed Synthetic Natural Gas-Air Flame with Variation in Fuel Compositions (합성천연가스의 조성변화에 따른 확산화염 연소특성)

  • Oh, Jeongseog;Dong, Sangeun;Yang, Jebok
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.9
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    • pp.829-836
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    • 2013
  • The combustion characteristics with variations in synthetic natural gas (SNG) compositions were studied in a lab-scale combustor. The objective of the current study is to investigate the flame stabilization, flame structure, and spectrometry in a non-premixed SNG flame with varying fuel compositions. For the analysis of light emission in SNG flames, we used a spectrometer. As experimental conditions, the fuel jet velocity at the nozzle exit $u_F$ was varied from 5 to 40 m/s and the coaxial air velocity $u_A$ was varies from 0 to 0.43 m/s. The experiments showed that the flame stability increased with the hydrogen component in SNG.

Effect Study of Fuel Specifications on Biofuels Policy in Transport Sector (수송용 바이오연료 정책에 따른 품질기준 영향에 관한 연구)

  • Park, Jo-Yong;Kim, Jae-Kon;Min, Kyong-IL;Park, Cheon-kyu;Ha, Jong-Han
    • Journal of the Korean Applied Science and Technology
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    • v.32 no.4
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    • pp.767-780
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    • 2015
  • Transport biofuels produced from biomass can be substituted for petroleum fuels due to GHG reduction, sustainability and environmental friendly. Mandates and targets of biofuels are announced in the European union, United states and other countries worldwide and promoted by the government policies. This paper reviewed current status of the national biofuels policies and fuel specifications in transport sector. EU biofuels policy shifted and GHG emission reduction became the main focus of the policy. There are specification requirements for biofuels in the U.S. under the RFS2, but there are other polices as well that serve to promote the uptake of biofuels both at the federal and state level. Korea government has allowed 2.3% oxygen in gasoline to come from oxygenates, increased the biodiesel blend mandate from B2 to B2.5 effective from Jul. 31, 2015.

A study on characteristics of each operation mode for hybrid electric propulsion ship by operation circumstances (선박 운전 환경에 따른 하이브리드 전기추진선박의 운전모드별 출력 특성에 관한 연구)

  • Kim, Jong-Su;Jeon, Hyeon-Min;Kim, Deok-Ki
    • Journal of Advanced Marine Engineering and Technology
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    • v.41 no.3
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    • pp.245-250
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    • 2017
  • Worldwide environmental regulations have been enhanced for emission reduction of greenhouse gases and air pollutants; accordingly, some measures were prepared. Furthermore, the need for effective and reasonable energy-saving methods is growing in accordance with that for environmental pollution minimization. In the case of marine engineering, techniques for the development of eco-friendly vessels have been actively studied, including reduction of exhaust gas emissions, development of alternative fuel, and development of a new propulsion system. In this study, we presented the basic concepts and analyzed the speed, current, voltage, and output power characteristics of each operating mode, i.e., operating mode of battery, generator, and full power.

Effects of TiN and ZrN Coating on Surface Characteristics of Orthodontic Wire (교정용 와이어의 표면특성에 미치는 TiN 및 ZrN 코팅영향)

  • Kim, W.G.;Kim, D.Y.;Choe, H.C.
    • Journal of the Korean institute of surface engineering
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    • v.41 no.4
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    • pp.147-155
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    • 2008
  • The dental orthodontic wire provides a good combination of strength, corrosion resistance and moderate cost. The purpose of this study was to investigate the effects of TiN and ZrN coating on corrosion resistance and physical property of orthodontic wire using various instruments. Wires(round type and rectangular type) were used, respectively, for experiment. Ion plating was carried out for wire using Ti and Zr coating materials with nitrogen gas. Ion plated surface of each specimen was observed with field emission scanning electron microscopy(FE-SEM), energy dispersive X-ray spectroscopy(EDS), atomic force microscopy(AFM), vickers hardness tester, and electrochemical tester. The surface of TiN and ZrN coated wire was more smooth than that of other kinds of non-coated wire. TiN and ZrN coated surface showed higher hardness than that of non-coated surface. The corrosion potential of the TiN coated wire was comparatively high. The current density of TiN coated wire was smaller than that of non-coated wire in 0.9% NaCl solution. Pit nucleated at scratch of wire. The pitting corrosion resistance $|E_{pit}-E_{rep}|$ increased in the order of ZrN coated(300 mV), TiN coated(120 mV) and non-coated wire(0 mV).

Development of Intermediate Temperature Fuel Cell Using a Solid Proton Conductor (고체 수소이온 전도체를 이용한 중온형 연료전지 개발)

  • Seo, Dong-Ho;Kim, Hong-Rok;Shakkthivel, P.;Shul, Yong-Gun
    • Journal of the Korean Electrochemical Society
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    • v.11 no.1
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    • pp.22-32
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    • 2008
  • Because of an emerging importance of clean energy, fuel cells are attract more attention due to their ability to produce high efficient power without any harmful emission. Fuel cells are energy conversion device with directly convert chemical energy into electrical energy by the chemical reactions, which have potential applications in automobile, spacecraft, stationary, industrial and home appliances. Recently there are gaining demand to develop an intermediate temperature fuel cell and available proton conductors at $200{\sim}500^{\circ}C$, which promising operating temperatures range for both material science and energy conversion processes. In this paper, we have reviewed electrochemical properties and current technology of solid state proton conductors. In addition, development of intermediate temperature fuel cell using the perovskite-type solid protonic conductor is also discussed.

An Aptamer-Based Electrochemical Sensor That Can Distinguish Influenza Virus Subtype H1 from H5

  • Lee, Jin-Moo;Kim, JunWon;Ryu, Ilhwan;Woo, Hye-Min;Lee, Tae Gyun;Jung, Woong;Yim, Sanggyu;Jeong, Yong-Joo
    • Journal of Microbiology and Biotechnology
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    • v.27 no.11
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    • pp.2037-2043
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    • 2017
  • The surface protein hemagglutinin (HA) mediates the attachment of influenza virus to host cells containing sialic acid and thus facilitates viral infection. Therefore, HA is considered as a good target for the development of diagnostic tools for influenza virus. Previously, we reported the isolation of single-stranded aptamers that can distinguish influenza subtype H1 from H5. In this study, we describe a method for the selective electrical detection of H1 using the isolated aptamer as a molecular probe. After immobilization of the aptamer on Si wafer, enzyme-linked immunosorbent assay (ELISA) and field emission scanning electron microscopy (FE-SEM) showed that the immobilized aptamer bound specifically to the H1 subtype but not to the H5 subtype. Assessment by cyclic voltammetry (CV) also demonstrated that the immobilized aptamer on the indium thin oxide-coated surface was specifically bound to the H1 subtype only, which was consistent with the ELISA and FE-SEM results. Further measurement of CV using various amounts of H1 subtype provided the detection limit of the immobilized aptamer, which showed that a nanomolar scale of target protein was sufficient to produce the signal. These results indicated that the selected aptamer can be an effective probe for distinguishing the subtypes of influenza viruses by monitoring current changes.

Pressure Retarded Osmosis Process: Current Status and Future (염도차를 이용한 압력지연삼투 공정의 현황과 미래)

  • Kim, Jihye;Kim, Seung-Hyun;Kim, Joon Ha
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.11
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    • pp.791-802
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    • 2014
  • Energy shortage is being exacerbated due to the increase of energy consumption and depletion of fossil fuels. In order to release the energy crisis, new types of energy resources such as small hydropower, solar power, wind power and biomass have been already developed or actively researched. Recently, osmotic power, which harvests energy from salinity gradient between seawater and fresh water, is considered as a feasible candidate. Among the osmotic power processes, pressure retarded osmosis (PRO) is widely gaining attention because of no emission of carbon dioxide and less sensitivity to the external environmental conditions. However, PRO process is facing difficulties such as the lack of specialized PRO membrane and optimization technologies. Therefore, PRO was reviewed in this paper in terms of theoretical background, membrane development, process development and fouling mechanism to provide insights and suggest the future direction of PRO research.

Research on How to Set 3rd Phase Target Water Quality on the Boundary between Metropolitan Cities/Dos Specified in Nakdong River Basin (낙동강수계 3단계 광역시·도 경계지점 목표수질 설정 방법 연구)

  • Hwang, Ha Sun;Park, Ji Hyung;Kim, Yong Seok;Rhew, Doug Hee;Choi, Yu Jin;Lee, Sung Jun
    • Journal of Korean Society on Water Environment
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    • v.33 no.1
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    • pp.70-77
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    • 2017
  • Total Pollution Load Control (TPLC) is a system for managing the discharge load assigned by satisfying the Target Water Quality (TWQ) in Standard Flow Conditions (SFC). TWQ for a between Metropolitan Cities/Dos Specified (Cites/Dos TWQ) is very important to be the basis of each Unit Watershed TWQ. The purpose of this study was to establish a rational and scientific 'Calculation Metohd of Cites/Dos TWQ'. A methodology for the 3rd phase 'Cites/Dos TWQ' was proposed in this study based on review of the past phase (1rd and 2rd) 'Cites/Dos TWQ' in nakdong river. And utilized water quality model to estimate 3rd phase 'Cites/Dos TWQ' The allocation method of individual discharge sources are important for estimating 'Cites/Dos TWQ' In this case, the key point of the method of calculating the total allowable individual sources is the balance of the equity and the efficiency between individual sources of reduced pollutants. Thus, water quality shall be determined with regard to the current emission levels, the reduction capacity and the technical possibilities of individual sources. We estimate 3rd phase 'Cites/Dos TWQ' according to the 'Calculation Method of Cites/Dos TWQ'.

The present and future of SWRO-PRO hybrid desalination technology development (SWRO-PRO 복합해수담수화 기술의 현재와 미래)

  • Chung, Kyungmi;Yeo, In-Ho;Lee, Wonil;Oh, Young Khee;Park, Tae Shin;Park, Yong-gyun
    • Journal of Korean Society of Water and Wastewater
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    • v.30 no.4
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    • pp.401-408
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    • 2016
  • Desalination is getting more attention as an alternative to solve a global water shortage problem in the future. Especially, a desalination technology is being expected as a new growth engine of Korea's overseas plant business besides one of the solutions of domestic water shortage problem. In the past, a thermal evaporation technology was a predominant method in desalination market, but more than 75% of the current market is hold by a membrane-based reverse osmosis technology because of its lower energy consumption rate for desalination. In the future, it is expected to have more energy efficient desalination process. Accordingly, various processes are being developed to further enhance the desalination energy efficiency. One of the promising technologies is a desalination process combined with Pressure Retarded Osmosis (PRO) process. The PRO technology is able to generate energy by using osmotic pressure of seawater or desalination brine. And the other benefits are that it has no emission of $CO_2$ and the limited impact of external environmental factors. However, it is not commercialized yet because a high-performance PRO membrane and module, and a PRO system optimization technology is not sufficiently developed. In this paper, the recent research direction and progress of the SWRO-PRO hybrid desalination was discussed regarding a PRO membrane and module, an energy recovery system, pre-treatment and system optimization technologies, and so on.