Browse > Article
http://dx.doi.org/10.7314/APJCP.2014.15.7.3253

Role of Household Exposure, Dietary Habits and Glutathione S-Transferases M1, T1 Polymorphisms in Susceptibility to Lung Cancer among Women in Mizoram India  

Phukan, Rup Kumar (Regional Medical Research Centre, ICMR (NE Region))
Saikia, Bhaskar Jyoti (Regional Medical Research Centre, ICMR (NE Region))
Borah, Prasanta Kumar (Regional Medical Research Centre, ICMR (NE Region))
Zomawia, Eric (Civil Hospital, Aizawl Upper Bazar)
Sekhon, Gaganpreet Singh (Regional Medical Research Centre, ICMR (NE Region))
Mahanta, Jagadish (Regional Medical Research Centre, ICMR (NE Region))
Publication Information
Asian Pacific Journal of Cancer Prevention / v.15, no.7, 2014 , pp. 3253-3260 More about this Journal
Abstract
Background: A case-control study was conducted to evaluate the effect of household exposure, dietary habits, smoking and Glutathione S-Transferases M1, T1 polymorphisms on lung cancer among women in Mizoram, India. Materials and Methods: We selected 230 newly diagnosed primary lung cases and 460 controls from women in Mizoram. Multivariate logistic regression analysis was performed to estimate adjusted odds ratio (OR). Results: Exposure of cooking oil fumes (p<0.003), wood as heating source for cooking (p=0.004), kitchen inside living room (p=0.001), improper ventilated house (p=0.003), roasting of soda in kitchen (p=0.001), current smokers of tobacco (p=0.043), intake of smoked fish (p=0.006), smoked meat (p=0.001), Soda (p<0.001) and GSTM1 null genotype (p=0.003) were significantly associated with increased risk of lung cancer among women in Mizoram. Significantly protective effect was observed for intake of bamboo shoots (p=<0.001) and egg (p<0.001). A clear increase in dose response gradient was observed for total cooking dish years. Risk for lung cancer tends to increase with collegial effect of indoor environmental sources (p=0.022). Significant correlation was also observed for interaction of GST polymorphisms with some of dietary habits. Conclusions: We confirmed the important role of exposure of cooking oil emission and wood smoke, intake of smoked meat, smoked fish and soda (an alkali preparation used as food additives in Mizoram) and tobacco consumption for increase risk of lung cancer among Women in Mizoram.
Keywords
Cooking oil fumes; lung cancer; Mizoram; women; bamboo shoots;
Citations & Related Records
Times Cited By KSCI : 5  (Citation Analysis)
연도 인용수 순위
1 Yu ITS, Chiu Y, Au JSK, Wong T, Tang J (2006). Dose-response relationship between cooking fumes exposures and lung cancer among Chinese non-smoking women. Cancer Res, 66, 4961-7.   DOI   ScienceOn
2 Wenzlaff AS, Cote ML, Bock CH, Land SJ, Schwartz AG (2005). GSTM1, GSTT1 and GSTP1 polymorphisms, environmental tobacco smoke exposure and risk of lung cancer among never smokers: a population-based study. Carcinogenesis, 26, 395-401.
3 Yang SC, Jenq SN, Kang ZC, Lee H (2000). Identification of benzo (a) pyrene 7, 8-diol 9, 10-epoxide N2-deoxyguanosine in human lung adenocarcinoma cells exposed to cooking oil fumes from frying fish under domestic conditions. Chem Res Toxicol, 13, 1046-50.   DOI
4 Ye Z, Song H, Higgins JPT, Pharoah P, Danesh J (2006). Five glutathione s-transferase gene variants in 23,452 cases of lung cancer and 30,397 controls: meta-analysis of 130 studies. PLoS Med, 3, 91.   DOI
5 Zhong L, Goldberg MS, Gao Y, Jin F (1999). Lung cancer and indoor air pollution arising from Chinese-style cooking among nonsmoking women living in Shanghai, China. Epidemiol, 10, 488-94.   DOI   ScienceOn
6 Shen M, Chapmanb RS, He X, et al (2008). Dietary factors, food contamination and lung cancer risk in Xuanwei, China. Lung cancer, 61, 275-82.   DOI
7 Sambrook J, Russel DW (2001). Purification of nucleic acid b Extraction with phenol chloroform: in molecular cloning. Vol 3. 3rd eds. Appendix 8. cold spring harbor NY, US: cold spring harbor laboratory press.
8 Sellappa S, Prathyumnan S, Joseph S, et al (2009). XRCC1399 and hOGG1326 polymorphisms and frequencies of micronuclei, comet and chromosomal aberrations among tobacco chewers: a south Indian population study. Asian Pacific J Cancer Prev, 10, 1057-62.
9 Senthilkumar KP, Thirumurugan R (2012). GSTM1 and GSTT1 allele frequencies among various Indian and non-Indian ethnic groups. Asian Pacific J Cancer Prev, 13, 6263-7.   과학기술학회마을   DOI   ScienceOn
10 Stołyhwo A, Sikorski ZE (2005). Polycyclic aromatic hydrocarbons in smoked fish-a critical review. Food Chem, 91, 303-11.   DOI   ScienceOn
11 Straif K, Baan R, Grosse Y, et al (2006). Carcinogenicity of household solid fuel combustion and of high-temperature frying. Lancet Oncol, 7, 977-8.   DOI
12 Viksna IS, Morozovs A, Bartkevics V, Kukare A (2008). Levels of benzo (a) pyrene (BaP) in fish, dmoked according to different procedures benzo (a) pirēna (BaP) saturs zivis, tas kupinot dazados apstaklos. LLU Raksti, 21, 24-9.
13 Wang A, Sun C, Li L, Huang J, Chen Q (2002). Relationship of tobacco smoking, CYP1A1, GSTM1 gene polymorphism and esophageal cancer in Xi'an. World J Gastroenterol, 8, 49-53.   DOI
14 Nosheen M, Ishrat M, Malik FA, Baig RM, Kayani MA (2010). Association of GSTM1 and GSTT1 gene deletions with risk of head and neck cancer in Pakistan: a case control study. Asian Pacific J Cancer Prev, 11, 881-5.
15 Miculis J, Valdovska A, Sterna V, Zutis J (2011). Polycyclic aromatic hydrocarbons in smoked fish and meat. Agronomy Research, 9, 439-42.
16 Murff HJ, Shu X, Li H, et al (2011). Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: a prospective cohort study. Int J Cancer, 128, 1434-41.   DOI
17 National Cancer Registry Programme (NCRP) (2010). Three-year report of the population based cancer registries 2006-2008. (First report of 20 PBCRs in India), Bangalore. Indian Council Med Res, 11, 70-90.
18 Phukan RK, Narain K, Zomawia E, Hazarika NC, Mahanta J (2006). Dietary habits and stomach cancer in Mizoram, India. J Gastroenterol, 41, 418-24.   DOI
19 Pisani P, Srivatanakul P, Randerson-Moor J, et al (2006). GSTM1 and CYP1A1 polymorphisms, tobacco, air pollution and lung cancer: a study in rural Thailand. Cancer Epidemiol Biomarkers Prev, 15, 667-74.   DOI
20 Phukan RK, Zomawia E, Narain K, Hazarika NC, Mahanta J (2005). Tobacco use and stomach cancer in Mizoram, India. Cancer Epidemiol Biomarkers Prev, 14, 1892-6.   DOI   ScienceOn
21 Reid BC, Ghazarian AA, DeMarini DM, et al (2012). Research opportunities for cancer associated with indoor air pollution from solid-fuel combustion. Environ Health Persp, 120, 1495-8.   DOI
22 Rothman N, Poirier MC, Baser ME, et al (1990). Formation of polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood cells during consumption of charcoal-broiled beef. Carcinogenesis, 11, 1241-3.   DOI
23 Ko Y, Cheng LS, Lee C, et al (2000). Chinese food cooking and lung cancer in women nonsmokers. Am J Epidemiol, 151, 140-7.   DOI   ScienceOn
24 Jourenkova-Mironova N, Wikman H, Bouchardy C, et al (1998). Role of glutathione s-transferase GSTM1, GSTM3, GSTP1 and GSTT1 genotypes in modulating susceptibility to smoking-related lung cancer. Pharmacogenetics, 8, 495-502.   DOI
25 Kelsey KT, Spitz MR, Zuo ZF, Wiencke JK (1997). Polymorphisms in the glutathione s-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States). Cancer Causes and Control, 8, 554-9.   DOI   ScienceOn
26 Kiran B, Karkucak M, Ozan H, et al (2010). GST (GSTM1, GSTT1, and GSTP1) polymorphisms in the genetic susceptibility of Turkish patients to cervical cancer. J Gynecol Oncol, 21, 169-73.   DOI
27 Marchand JL, Luce D, Goldberg P, et al (2002). Dietary factors and the risk of lung cancer in New Caledonia (South Pacific). Nutr Cancer, 42, 18-24.   DOI   ScienceOn
28 Koo LC, Ho JH, Tominaga S, et al (1995). Is Chinese incense smoke hazardous to respiratory health? Indoor and Built Environ, 4, 334-43.   DOI
29 Lewis NM, Seburg S, Flanagan NL (2000). Enriched Eggs as a source of N-3 polyunsaturated fatty acids for humans. Poult Sci, 79, 971-4.   DOI
30 Lissowska J, Bardin-Mikolajczak A, Fletcher T, et al (2005). Lung cancer and indoor pollution from heating and cooking with solid fuels. Am J Epidemiol, 162, 326-33.   DOI
31 Metayer C, Wang Z, Kleinerman RA, et al (2002). Cooking oil fumes and risk of lung cancer in women in rural Gansu, China. Lung Cancer, 35, 111-7.   DOI   ScienceOn
32 Chongtham N, Bisht MS, Haorongbam S (2011). Nutritional properties of bamboo shoots: potential and prospects for utilization as a health food. Comper Rev Food Sci Food Saf, 10, 153-69.   DOI
33 Chaturvedi HK, Phukan RK, Zoramtharga K, Hazarika NC, Mahanta J (1998). Tobacco use in mizoram, India: sociodemographic differences in pattern. Southeast Asian J Trop Med Public Health, 29, 66-70.
34 China's Health Statistics Yearbook (2010). Ministry of health. China: Peking Union Medical College Press, 2010, pp 4625. available from: www.purpleculture.net/chinas-health-statistics-yearbook-2010-p-4625.
35 Cho H, Lee S, Ki C, Kim J (2005). GSTM1, GSTT1 and GSTP1 polymorphisms in the Korean population. Korean Med Sci, 20, 1089-92.   과학기술학회마을   DOI   ScienceOn
36 Gong J, Wu X, Lu B, Zhang Y (2010). Safety evaluation of polyphenol-rich extract from bamboo shavings. Afr J Biotech, 9, 77-86.
37 D'Souza ND, Murthy NS, Aras RY. (2013). Projection of cancer incident cases for India -till 2026. Asian Pac J Cancer Prev, 14, 4379-86.   과학기술학회마을   DOI   ScienceOn
38 Ferlay J, Shin HR, Bray F, et al (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127, 2893-917.   DOI   ScienceOn
39 Galati G, Brien PJO (2004). Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radical Bio Med, 37, 287-303.   DOI   ScienceOn
40 Hung HS, Wu WJ, Cheng YW, et al (2007). Association of cooking oil fumes exposure with lung cancer: involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro. Mutat Res, 628, 107-16.   DOI
41 IARC (International Agency for Research on Cancer). (2010). Household use of solid fuels and high-temperature frying. IARC monographs on the evaluation of carcinogenic risks to humans. lyon, France: IARC Press, 95, 1-430.
42 Tredaniel J, Boffetta P, Saracci R, Hirsch A (1994). Exposure to environmental tobacco smoke and risk of lung cancer: the epidemiological evidence. Eur Respir J, 7, 1877-88.   DOI   ScienceOn
43 Malakar M, Devi KR, Phukan RK, et al (2014). p53 codon 72 polymorphism interactions with dietary and tobacco related habits and risk of stomach cancer in Mizoram, India. Asian Pac J Cancer Prev, 15, 717-23.   과학기술학회마을   DOI   ScienceOn