• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.576-582
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• 2017

The switching system in a maglev train is an indispensable element for distributing train routes, and it should be designed to ensure safe operation. Unlike conventional wheels on rails, the switching track in EMS-type maglev is supported by a group of 3 to 4 steel girders. When the vehicle changes its route, the segmented track allows the girders to change from a straight position to a curved one with a small radius of curvature. Hence, the structural characteristics of the segmented switching system may affect the levitation stability of the maglev vehicle. This study experimentally evaluates the dynamic interaction between maglev vehicles and a segmented switching system. The results may be helpful for improving the switching system. The measured levitation and lateral air gaps were evaluated at a vehicle speed of 25 km/h, and the ride quality of the Maglev vehicle was determined to be "comfortable" according to the UIC 513 standard.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.12
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• pp.5477-5485
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• 2011

This study comparatively analyzed the instrumentation and the voicing structure, which were shown in the film music titled "Star Wars-Main Title" by John Williams(1932~), with analytical technique that the writer mapped out, and aimed to discover the progression principle in orchestration based on the results. Also, it applied a functional part-division method that was classified and distributed into 3 functional parts according to auditory cognitive level as for each of functional elements such as the musical element. And, it made it pattern for the vertical structure and the voicing structure in musical instruments, which were distributed to each functional part based on this, and comparatively analyzed the standard point in a change which were shown according to progression of music, namely, the operating technique. As for the results of this study, first, each theme has specific instrumentation pattern. Unity was emphasized by consistently organizing those things in exposition, reprise, and recapitulation of each theme. To reinforce diversity, an attempt was made such as adding and reducing auxiliary instruments in the middle part and the rear part. Second, even in a change of instrumentation pattern by passage in accordance with a change in theme amid each part, the same instrumental group was organized in the middle part, thereby having maintained unity. Third, to strengthen diversity by clause, which is forming each theme, a continuous change in voicing pattern was created by adding or omitting a part. Fourth, the voicing concentration was maintained the structure of "thinness-thickness" in the whole musical piece. However, in part 2 that is repeated theme 3, diversity was pursued with a unique change of "thickness-thickness." Fifth, in part 4 that is indicated theme 4, the other diversity was intensified with the inverted range in the front part and the middle part. Accordingly, based on the conclusions that were indicated in this work, it is desired to be conducive to understanding the horizontal consideration and the progression principle of orchestration.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.9
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• pp.6345-6359
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• 2015

This study aims to clarify the concept of 'Low-carbon urban regeneration', to extract planning elements according to it, and to establish the planning system. In order to extract the elements, matrix analysis was conducted between planning elements of urban regeneration and Low-carbon cities, and the focus group interview(FGI) was used. Derived elements from this process were restructured for the new planning system. In addition, in-depth case analysis was performed to verify the suitability and effects of planning elements and system. The result showed that planning element of Low-carbon urban regeneration can be sorted in 37 elements in 5 categories. In-depth analysis indicated that established planning elements were importantly dealt in cases and played a significant role in urban regeneration and carbon reduction. Also, it showed that those elements had a significant relationship with adaptation and mitigation, the two responding strategies to the climate change. Elements highly contributing to urban regeneration were Urban Structure, Transportation, Policy while elements affecting carbon reduction were Transportation, Green & Blue space, Energy & Material field.

• Korean Journal of Applied Biomechanics
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• v.18 no.3
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• pp.61-69
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• 2008

The purpose of this study is to examine the success or failure on the balance beam in element group requirements posture which is bending salto side-ward tucked through kinetic analysis. The national team players were participated. The goal was to present training methods to coaches and athletes so as to provide scientifically useful information. The results from this study were summarized as below. When the performance was successful, the features of the body's center of gravity during the side somersault motion showed to spread from the center of the balance beam and the center of the gravity moved to the direction of the body's rotation. In the spring sections - event2 and 3, when the performance was successful, up/down fluctuation became more wider and increased air time. It supported the result that the projecting variable was higher than in failure trial. In addition, the right side hip joint angles and speed, and angular velocity as jumping up for a leap were larger than in failure trial. Those variables showed the optimal conditions for a leap. By increasing the speed of the upper limb from the shoulder and the speed of the shoulder joint angular velocity, the momentum was increased. Especially the right side shoulder joint angular velocity increased dramatically because the right leg was held. As to the side somersault motion, the angular momentum of successful trial with respect to x-axis was bigger than failed trial. It indicated that the increasing angular momentum with respect to x-axis was an important factor in flying motion. Besides, as to side somersault, the appropriate proportion of angular momentum with respect to y-axis and z-axis was a key to successful trails.

• Korean Journal of Medicinal Crop Science
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• v.28 no.4
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• pp.276-286
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• 2020

Background: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease associated with multiple metabolic disorders. The medicinal plant Curcuma longa L. is widely distributed in Asia and has been used to treat a spectrum diseases in clinical practice. To date, there are inadequate reports of the effects of C. longa 50% EtOH extract (CE) on NAFLD. Therefore, in this study, we evaluate the CE on an NAFLD animal and elucidate the mechanism of action. Methods and Results: C57BL/6J mice fed a methionine-choline deficient diet (MCD) were treated with CE or milk thistle, and changes in inflammation and stetosis were assessed. Experimental animals were divided into six group (n = 10); Normal, MCD, MCD + CE 50 mg/kg/day (CE 50), MCD + CE 100 mg/kg/day (CE 100), MCD + CE 150 mg/kg/day (CE 150), and the Control, MCD + Milk thistle 150 mg/kg/day (MT 150). Body weight, liver weight, liver function, and histological changes were assessed in experimental animals. Quantitative real-time polymerase chain reaction and western blot analyses were performed on samples collected after 4 weeks of treatment. We observed that CE administration improved MCD-diet-induced lipid accumulation, and triglyceride (TG) and total cholesterol (TC) levels in serum. Treatment with CE also decreased hepatic lipogenesis through modulation of the sterol regulatory element binding protein-1 (SREBP-1), CCAAT-enhancer binding protein α (C/EBPα), fatty acid synthase (FAS), and peroxisome proliferator-activated receptor γ (PPARγ) expresion. In addition, the use of CE increased adenosine monophosphate-activated protein kinase (AMPK) phosphorylation and inhibited the up-regulation of toll-like receptor (TLR)-2 and TLR-4 signaling and the production of inflammatory mediators. Conclusions: In this report, we observed that CE regulated lipid accumulation in an MCD dietinduced NAFLD model by decreasing lipogenesis. These data suggeste that CE could effectively protect mice against MCD-induced NAFLD, by inhibiting the TLR-2 and TLR-4 signaling cascades.

• Resources Recycling
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• v.27 no.4
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• pp.50-56
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• 2018

For the purpose of optimizing the counter current extraction process for separation of [Pr, Nd, Sm] group and [La] in mixed solution using Cyanex 572 as an extractant, the theory of Xu Guangxian was derived for calculating the optimized extraction factors. From the basic batch test result, the separation factor was 16.80 at extraction process and 21.48 at scrubbing process, and the loading capacity of 1.0 M Cyanex 572 was 0.12 M of rare earth element. The process parameters such as the stage number at extraction and scrubbing process, the flow rate ratio of feed and solvent solution can be calculated using an equation of optimum extraction ratio proposed by Xu Guangxian. From the result of calculation, 7 extraction stages and 4 scrubbing stages were required for rare earth separation, and the flow rate ratio of feed solution, solvent solution, scrubbing solution was 25 : 5.67 : 12.27.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.1
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• pp.1-5
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• 2019

In this paper, the experimental study and finite elements analysis were conducted on homogeneous and dissimilar metals single lap-shear bonded joints to investigate the factor that affect the joint failure load. It was found that factors which have the significant effects on the failure load of the joint was stiffness of the adherends. And from experimental results, it can be confirmed that the failure load increases linearly with overlap length increases. And the failure load of dissimilar metal joints is approximately 1KN(10~17%) larger than homogeneous metal joints. In order to confirm this phenomenon, the stress distribution and strain distribution of the specimens were analyzed through the finite element analysis. The difference between homogeneous metals joints and dissimilar metals joints is that stress and strain in adhesive are concentrated at the end of the overlap zone close to aluminium which has lower rigidity than aluminium in case of dissimilar metals joints. From high rigidity of steel, the stress concentration in bonds are decreased and it cause increase of the failure strength at dissimilar metal joints.

• Journal of Nutrition and Health
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• v.52 no.1
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• pp.17-25
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• 2019

Purpose: Obesity is a major health problem of global significance because it is clearly associated with an increased risk of health problems, such as nonalcoholic fatty liver disease (NAFLD), diabetes, cardiovascular diseases, and cancer. Lonicera caerulea (LC) originates from high mountains or wet areas and has been used as a traditional medicine in northern Russia, China, and Japan. LC contains a range of bioactive constituents, such as vitamins, minerals, and polyphenols. This study examined the anti-obesity effects of LC during differentiation in preadipocytes. Methods: The cell viability assay was performed after the differentiation of 3T3-L1 cells for 7 days. Oil Red O staining was used to visualize the changes in lipid droplets in 3T3-L1 cells and mouse adipose-derived stem cells (MADSCs). The mRNA expression of obesity-related genes was determined by quantitative real-time PCR. Results: According to the results of Oil Red O staining, the lipid levels and size of lipid droplets in the adipocytes were reduced and the LC extract (LCE, 0.25-1 mg/mL) markedly inhibited adipogenesis in a dose-dependent manner. The treatment of LCE also decreased the mRNA expression of peroxisome proliferator-activated receptor ${\gamma}$ ($PPAR{\gamma}$), CCAAT/enhancer binding protein-${\alpha}$ ($C/EBP{\alpha}$), and sterol regulatory element binding protein 1 (SREBP1) in 3T3-L1 cells. Western blot analysis showed that the $PPAR{\gamma}$, $C/EBP{\alpha}$, and SREBP1 protein levels in both 3T3-L1 and MADSC were reduced in a dose-dependent manner. Conclusion: These results suggest that LCE can inhibit adipogenic differentiation through the regulation of adipogenesis-related markers.

• Korean Journal of Medicinal Crop Science
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• v.28 no.6
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• pp.395-411
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• 2020

Background: This study investigated the anti-obesity effect of the flavonoid rich fraction (FRF) and its constituent, rutin obtained from the leaf of Morus alba L., on the lipid accumulation mechanism in 3T3-L1 adipocyte and C57BL/6 mouse models. Methods and Results: In Oil Red O staining, FRF (1,000 ㎍/㎖) treatments showed inhibition rate of 35.39% in lipid accumulation compared to that in the control. AdipoRedTM assay indicated that the triglyceride content in 3T3-L1 adipocytes treated with FRF (1,000 ㎍/㎖) was reduced to 23.22%, and free glycerol content was increased to 106.04% that of the control. FRF and its major constituent, rutin affected mRNA gene expression. Rutin contributed to the inhibition of Sterol regulatory element binding protein-1c (SREBP-1c) gene expression, and inhibited the transcription factors SREBP-1c, peroxisome proliferator-activated receptor gamma (PPAR-γ), CCAAT/enhancer binding protein α (C/EBPα), fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC). In addition, the effect of FRF administration on obesity development in C57BL/6 mice fed high-fat diet (HFD) was investigated. FRF suppressed weight gain, and reduced liver triglyceride and leptin secretion. FRF exerted potential anti-inflammatory effects by improving insulin resistance and adiponectin levels, and could thus be used to help counteract obesity. The mRNA expressions of PPAR-γ, FAS, ACC, and CPT-1 were determined in liver tissue. Quantitative real-time PCR analysis was also performed to evaluate the expression of IL-1β, IL-6, and TNF-α in epididymal adipose tissue. Compared to the control group, mice fed the HFD showed the up-regulation in PPAR-γ, FAS, IL-6, and TNF-α genes, and down-regulation in CPT1 gene expression. FRF treatement markedly reduced the expression of PPAR-γ, FAS, IL-6, and TNF-α compared to those in HFD control, whereas increased the expression level of CPT1. Conclusions: These results suggest that the FRF and its major active constituent, rutin, can be used as effective anti-obesity agents.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.420-430
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• 2021

This was an investigative study to identify the role expectations for clinical research related tasks that ward nurses can participate in and the awareness of cooperation between ward nurses and clinical research nurses (CRNs) and the obstacles for the same. The subjects were 66 ward nurses and 65 CRNs. The data were analyzed using descriptive statistics, the two-sample t-test, and the 𝑥² test on SAS 9.3. As a result of this study, 4.56±0.41 ward nurses and 3.83±0.60 CRNs were found to have high role expectations of each other and statistically significant role expectations for ward nurses (p<.001). Significant differences were seen in the five categories of cooperation recognition between the two groups. Among the factors for cooperative disabilities, excessive work and lack of awareness of clinical research were ranked high. High role expectation becomes an element of role conflict. To organize the role of ward nurses and clinical research nurses in the new clinical research nursing work, procedures, establishing of effective practices, and the proper operation of an official system are expected to be necessary. To promote cooperation between the two groups, a culture of mutual trust and cooperation should be formed to enable each group to think of the other as partners and to recognize their expertise.