• Korean Journal of Medicinal Crop Science
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• v.12 no.6
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• pp.500-507
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• 2004

The establishment of an efficient protocol of plant regeneration from leaf explant cultures of Perilla spp. is reported. Regenerated shoots were obtained from leaf explant cultures on solid MS medium containing different concentrations of cytokinins and auxin. The effect of cytokonin and auxin differed depending on each acession. The combination treatments of high level of cytokinin and low level of auxin was more effective for plant regeneration in Perilla frutescens. The best concentration of sucrose was 3% for regeneration. Of spermidine, spermin and putrescine. treatments, the most effective treatment for plant regeneration was $10\;mg/{\ell}$ spermidine.

• BMB Reports
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• v.53 no.3
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• pp.142-147
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• 2020

Lipid accumulation in white adipose tissue is the key contributor to the obesity and orchestrates numerous metabolic health problems such as type 2 diabetes, hypertension, atherosclerosis, and cancer. Nonetheless, the prevention and treatment of obesity are still inadequate. Recently, scientists found that brown adipose tissue (BAT) in adult humans has functions that are diametrically opposite to those of white adipose tissue and that BAT holds promise for a new strategy to counteract obesity. In this study, we evaluated the potential of sinapic acid (SA) to promote the thermogenic program and lipolysis in BAT. SA treatment of brown adipocytes induced the expression of brown-adipocyte activation-related genes such as Ucp1, Pgc-1α, and Prdm16. Furthermore, structural analysis and western blot revealed that SA upregulates protein kinase A (PKA) phosphorylation with competitive inhibition by a pan-PKA inhibitor, H89. SA binds to the adenosine triphosphate (ATP) site on the PKA catalytic subunit where H89 binds specifically. PKA-cat-α1 gene-silencing experiments confirmed that SA activates the thermogenic program via a mechanism involving PKA and cyclic AMP response element-binding protein (CREB) signaling. Moreover, SA treatment promoted lipolysis via a PKA/p38-mediated pathway. Our findings may allow us to open a new avenue of strategies against obesity and need further investigation.

• Journal of the Korean Institute of Landscape Architecture
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• v.44 no.6
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• pp.107-119
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• 2016

Currently, 230 domestic tourist destinations have been designated, established, and operated in accordance with the Tourism Promotion Act. According to the results of preceding research, more than 30% of them have been getting into the stagnation or decline stage. This is becoming a burden to local governments operating and managing tourist destinations, making it necessary to seek resolution measures. Thus, this study determined the activation elements of stagnant/declined tourist destinations regeneration to deal with problems of domestic stagnant or declined tourist destinations and also to regenerate rational and sustainable tourist destinations. This study conducted a survey with experts based on causes for stagnation and decline of domestic tourist destinations suggested by preceding research. Based on the survey results, the activation elements of stagnant/declined tourist destinations regeneration were drawn through the Delphi Technique and Analytic Hierarchy Process. And then the priority and weight of the drawn activation elements of stagnant/declined tourist destinations regeneration were drawn for the sake of reasonable project progress of tour site regeneration. In the results of the analysis, as activation elements of stagnant/declined tourist destinations regeneration, a total of seven upper-attributes, 23 sub-attributes, and 66 detailed-elements were drawn. It would be possible to raise the efficiency of projects and rational decision-making when executing future tourist destinations regeneration projects by using the activation elements drawn. Also, the drawn elements could be applied to the actual tourist destinations regeneration projects as measures for the stagnant/declined domestic tourist destinations' contribution to the vitalization of local economy based on sustainability, prohibition of thoughtless development of domestic tourism projects, and also efficient use of tourism resources.

• Journal of Korean Society of Environmental Engineers
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• v.27 no.8
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• pp.859-869
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• 2005

The commercial $V_2O_5-WO_3/TiO_2$ catalysts which had been exposed to the off gas from incinerator for a long time were regenerated by physical and chemical treatment. The catalytic properties and NOx conversion reactivity of those catalysts were examined by analysis equipment and NOx conversion experiment. The characterization of the catalysts were performed by XRD(x-ray diffractometer), BET, POROSIMETER, EDX(energy dispersive x-ray spectrometer), ICP(inductively coupled plasma), TGA(thermogravimetric analyzer) and SEM (scanning electron microscopy). NOx conversion experiment were performed with simulated off gas of the incinerator and $NH_3$ was used as a reductant of SCR reaction. Among the regeneration treatment methods which were applied to regenerate the aged catalysts in this study, it showed that the heat treatment method had excellent regeneration effect on the catalytic performance for NOx conversion. The catalytic performance of the regenerated catalysts with heat treatment method were recovered over than 95% of that of fresh catalyst. For the regenerated catalysts with the acid solution(pH 5) and the alkali solution(pH 12), the catalytic performance were recovered over than 90% of that of fresh catalyst. From the characterization results of the regenerated catalysts, the specific surface area was recovered in the range of $85{\sim}95%$ of that of fresh catalyst. S and Ca element, which are well known as the deactivation materials for the SCR catalysts, accumulated on the aged catalyst surface were removed up to maximum 99%. Among the P, Cr, Zn and Pb elements accumulated on the aged catalyst surface, P, Cr and Zn element were removed up to 95%. But the Pb element were removed in the range of $10{\sim}30%$ of that of fresh catalyst.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.52 no.7
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• pp.307-314
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• 2003

This paper presents a 3D shape optimization algorithm for electromagnetic devices using the design sensitivity analysis with finite element method. The structural deformation analysis based on the deformation theory of the elastic body under stress is used for mesh renewing. The design sensitivity and adjoint variable formulae are derived for the 3D finite element method with edge element. The results of sensitivity analysis are used as the input data of the structural analysis to calculate the relocation of the nodal points. This method makes it possible that the new mesh of analysis region can be obtained from the initial mesh without regeneration. The proposed algorithm is applied to the shape optimization of 3D electromagnet pole to net a uniform flux density at the target region.

• Journal of Ecology and Environment
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• v.48 no.2
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• pp.152-162
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• 2024

Background: Plant species of the alpine treeline ecotone are highly sensitive to climate change and may adjust their population dynamics, and functional traits in response to changing climate. This study examined regeneration patterns and leaf traits variations in an important treeline ecotone element Rhododendron campanulatum along the elevation gradient in western Nepal to assess its potential adaptive responses to climate change. The distribution range of R. campanulatum (3,400-3,800 m above sea level [a.s.l.]) was divided into five horizontal bands, each with a 100 m elevational range. Eight plots (10 m × 10 m) were sampled in each band, resulting into a total of 40 plots. In each plot, all R. campanulatum individuals and co-occurring tree species were counted. From each elevation, R. campanulatum leaf samples were collected to determine leaf dimensions, leaf density, specific leaf area (SLA), and stomatal density (SD). Results: The density-diameter curve indicated that R. campanulatum was regenerating well, with enhanced regeneration at higher elevation (3,800 m a.s.l.) than at lower. Tree canopy cover appeared to be the major determinant of R. campanulatum regeneration, as indicated by a higher number of seedlings in treeless stands. With increasing elevation, the leaf length, width, SLA, and stomata length decreased but leaf thickness and SD increased. Conclusions: Overall, a higher regeneration and lower SLA with the high SD in the leaves at the upper limit of the species distribution suggested that R. campanulatum is well adapted at its upper distribution range with the possibility of upslope range shift as temperature increases.

• BMB Reports
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• v.32 no.1
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• pp.45-50
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• 1999

We previously found three transcription factor-binding motifs in the rat p53 promoter. They are two recognition motifs of NF1-like protein (NF1-like element 1: -296 ~ -312, NF1-like element 2: -195 ~ -219) and a bHLH protein binding element (-142 ~ -146). In this study, we investigated the DNA-protein complex formation of the three elements with nuclear extracts from both normal and regenerating liver to find the element involved in the induced transcription of p53. The level of each DNA-protein complex on NF1-like and bHLH motifs was not changed. Instead, a new element located at -264 ~ -284 was detected in the DNase I footprinting assay with regenerating nuclear extract. This element has partial homology to the AP1 consensus motif. However, the competition studies with diverse oligonucleotides suggest that the binding protein is not AP1. An in vitro transcription assay shows that this element is important for the transcriptional activation of the rat p53 promoter. Therefore, for the induced transcription of the rat p53 promoter, the-264 ~ -284 region is required in addition to two NF1-like and one bHLH motif.

• Korean Institute of Interior Design Journal
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• v.23 no.3
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• pp.144-152
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• 2014

This study evaluated how folly is experimented in the contemporary architecture after 30 years when Bernard Tchumi first introduced it to the public by the modern transformation as a garden ornament. First, folly project has been carried out based on the general concept of energizing dwindling cities. However, it has changed to the direction of adding specific programs. Also, along urban regeneration that does not change deterioration of previous structures, Folly changed in the emphasis on readjust existing structure. Second, by having different designers presenting their own follies during the Osaka Expo, folly now has part on visual exhibition element. This has similarity with public art project, yet it could more actively intervene for urban regeneration compared to conventional environment sculpture. Third, folly is experimented as the event-installation art combined form of architecture and art where people could experience the space and enjoy art. Fourth, folly enabled the landscaping of architecture and expanding city planning. Recently Gwangju Folly invited various arts, social, and cultural professionals to converge city design with architecture, landscaping, and other diverse genres.

• Journal of Korea Planning Association
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• v.54 no.1
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• pp.108-117
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• 2019

The purpose of this study is to investigate whether the plan reflecting the place in cultural regeneration was implemented and whether it was a change of place in culture through culture analyze. Mullae-dong has changed its urban structure into a textile factory, a manufacturing industry, an ironworks+artistic complex, and the Mullae art factory has been organizing a festival that has been created by artists and residents alike in the Mullae creative village. However, prior to the creation of the Mullae art factory in the social element, self-sustaining programs of Mullae creative villages were derived, but now commercial space is mainly derived. Therefore, it is necessary to plan for coexistence of ironworks, cultural space and commercial space rather than expanding into commercial space. Geumcheon-gu Geumcheon-gu Geumcheon Art Factory has become an integrated complex where various industries coexist in industrial complex. Geumcheon Art Factory also holds an artist support program every year and actively works as an international creative exchange center in Seoul. However, programs that act as a mediator are not implemented since 2014, and the Open Studio stops once a year. Therefore, Geumcheon-gu needs to expand programs that can include local programs and programs that can be combined with local cultural media.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.9
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• pp.6345-6359
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• 2015

This study aims to clarify the concept of 'Low-carbon urban regeneration', to extract planning elements according to it, and to establish the planning system. In order to extract the elements, matrix analysis was conducted between planning elements of urban regeneration and Low-carbon cities, and the focus group interview(FGI) was used. Derived elements from this process were restructured for the new planning system. In addition, in-depth case analysis was performed to verify the suitability and effects of planning elements and system. The result showed that planning element of Low-carbon urban regeneration can be sorted in 37 elements in 5 categories. In-depth analysis indicated that established planning elements were importantly dealt in cases and played a significant role in urban regeneration and carbon reduction. Also, it showed that those elements had a significant relationship with adaptation and mitigation, the two responding strategies to the climate change. Elements highly contributing to urban regeneration were Urban Structure, Transportation, Policy while elements affecting carbon reduction were Transportation, Green & Blue space, Energy & Material field.