• Journal of Pharmaceutical Investigation
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• v.25 no.3
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• pp.249-264
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• 1995

Although liposome has many advantages as a pharmaceutical dosage form, its application in the industrial field has been limited because of some problems such as preparation method, reproducibility, scale-up, stability and sterilization etc. Liposomes prepared by microemulsification method had defined size, narrow size distribution, reproducibility and high entrapment efficiency. For enhancing the stability, the dry form of liposome was recommended. These types of liposome are proliposome and freeze-dried liposome. The liposome must have some properties for preparing of freeze-dried liposome; small size $(50{\sim}200\;nm)$, narrow size distribution and cryoprotectant. In this experiment, the liposomes containing 5-Fluorouracil(5-FU) and its prodrug(pentyl-5-FU-1-acetate; PFA, hexyl-5-FU-1-acetate; HFA) were made with soybean phosphatidylcholine, cholesterol, stearylamine(SA) and dicetyl phosphate(DCP) employing hydration method or microemulsification method using $Microfluidizer^{TM}$. Both or liposome types were MLV and MEL. After preparation, freeze drying and rehydration were performed. In the process of freezing, trehalose(Tr) was added as a cryoprotectant. Their evaluation methods were as follows; entrapment efficiency, mean particle size and size distribution, dissolution test, retain of entrapment efficiency and turbidity after freeze-drying. The results are summarized as belows. The entrapment efficiency of 5-FU was dependent on total lipid concentration and cholesterol content but that of PFA and HFA was decreased when cholesterol was added. When DCP and SA were added, entrapment efficiency was decreased. As the partition coefficient of drug was increased, entrapment efficiency was increased. Under the same condition, entrapment efficiency of MEL is similar to that of MLV. The mean particle size and size distribution of MEL were smaller than those of MLV. Dissolution rates of drug from both liposome types were comparatively similar. Dissolution rates of drugs with serum and liver homogenate were faster than without these material. After preparation of liposome, free drug was removed efficiency by Dowex 50W-X4. When liposome was freeze-dried and then rehydrated in the presence of Tr, characteristics of liposome were maintained well in MEL than MLV. Tr Was used successfully as a cryoprotectant in the process of freeze drying and the optimal ratio of Tr:Lipid was 4:1(g/g).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.7438-7442
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• 2014

An assessment of flocculation was performed by measuring the distribution of the floc size during sedimentation in water works. The size and number of flocs have a greater effect on an evaluation of the efficiency of flocculation rather than the turbidity. The data was collected in situ using particle image velocimetry and image analysis. The measurements were carried out at a water depth of 1m. The removal efficiency of the total organic compounds, UV absorbance and turbidity depended on the size and floc size distribution in flocculation as the G value. The G value of 50 sec-1, 30 sec-1 and 10 sec-1 showed the highest degree of efficiency in the case of an inlet water turbidity of 5 NTU, and the highest degree of efficiency was observed at a G value of 65 sec-1, 40 sec-1 and 10 sec-1 when the inlet water turbidity was 263 NTU. The number of flocs with a distribution of above $1,200{\mu}m$ was 14. The dynamics between two important growth mechanisms were investigated as the energy input changed. This is a certain method that makes use of the size and number of flocs as an efficiency assessment.

• Journal of the Korea Convergence Society
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• v.12 no.11
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• pp.19-26
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• 2021

A purpose of this study is to suggest distribution tariff regulation that encourages private investment on the energy efficiency industry of Ukraine. As the electricity market reform and the regulation introduction to encourage energy efficiency are ongoing in Ukraine, it is best time for Korean companies to enter to the market. Therefore, studies on the regulation and the market of Ukraine are required in advance. A simulation of private investment feasibility on AMI business is conducted on one of 32 DSOs in Ukraine. Through the simulation, the directions of RAB tariff regulation, which is the core of the distribution service tariff regulation, were derived. It is essential for DSOs to permit AMI lease assets, introduced by private investors, as regulated assets while other regulations are maintained as it is for investment. This study provides a practical basis by presenting objective data through simulation. It is expected to be helpful for overseas expansion of companies if the study is expanded to the various energy efficiency industries.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.12
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• pp.2059-2064
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• 2007

This paper analyzed distribution network reliability related with the increment of outages and duration time according to distribution facilities increasing. KEPCO introduced distribution automation system in 1998 which could recognize outage section by remotely monitoring the fault current and reduce the blackout area by remotely controlling distribution switches. As the result of this outage time reduction using distribution automation system, the minimum distribution automation rate was fined out in this paper on the base of analyzing diverse data and how many switches were used in distribution system to improve distribution network reliability at the situation of distribution facilities increasing. This result can be used as the model that an overseas utility company applies distribution automation system in the future.

• Journal of Communications and Networks
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• v.8 no.2
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• pp.169-174
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• 2006

In this paper, the algorithm of a methodology for the calculation of spectrum requirements was implemented. As well, the influence of traffic distribution ratio among radio access technology groups, spectral efficiency, and flexible spectrum usage (FSU) margin was analyzed in terms of the spectrum requirements, with a view toward for future development of international mobile telecommunication (IMT)-2000 and systems beyond IMT-2000. The calculated spectrum requirement in the maximum spectral efficiency case is reduced by approximately 40% compared to a minimum spectral efficiency case. The effect of the distribution ratio on the required spectrum is smaller than the effect of the spectral efficiency. As the flexible spectrum usage margin increases by 1.0 dB, the total spectrum requirement decreases by 0.9 dB. The required spectrum for the market input parameter, ${\rho}$ = 0.5 is 801.63 MHz, while the required spectrum for ${\rho}$ = 1.0 is 6295.4 MHz. This is equivalent to an increase of 785.32 %.

• The Journal of Industrial Distribution & Business
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• v.10 no.1
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• pp.9-17
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• 2019

Purpose - Urban agglomeration construction is one of national strategic plans to accelerate the development of industrialization and urbanization in China, which has threatened the eco-environmental quality at the same time. This paper selected the urban agglomeration in the middle reaches of the Yangtze River as the research area. Research design, data, and methodology - The the slack-based measurement (SBM) model considering undesirable outputs is applied to measure the eco-efficiency of this urban agglomerations during 2006-2015. Results - The empirical results show that average eco-efficiency of the urban agglomeration in the middle reaches of the Yangtze River is 0.595. Regional ecological development is unbalanced. The highest eco-efficiency is recorded at Wuhan Metropolitan Area, and the lowest one is at the Changsha-Zhuzhou-Xiangtan City Group. Energy consumption and waste dust emissions are the key factors led to ecological inefficiency. Based on this, potentials for energy saving and waste dust reducing are calculated. Conclusions - Finally, this study provides policy implications targeted to promote the coordinating development of economy and eco-environment under the construction of urban agglomeration.

• International Journal of Aeronautical and Space Sciences
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• v.4 no.1
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• pp.26-33
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• 2003

Recess is a geometrical configuration shape that the exit surface of an inner injector is located at a certain length inward from that of an outer injector. It is known to have the characteristics that it can augment mixing efficiency and flame stabilization through internal mixing of propellant in it. So, various experiments, such as backlit stroboscopic photography, phase Doppler particle analyzer(PDPA) and mechanical patternator, were performed at several recess lengths to grasp its effect on the spray characteristics of spray angle, breakup length, atomization and' mixing. Recess length was normalized to dimensionless recess number and two principal mechanisms of impingement and swirl recovery were introduced to explain its influence on the spray characteristics. The effect of recess on SMD doesn't appear significantly near the recess number where mixing efficiency attains to the maximum, whereas mass distribution and mixing efficiency are changed considerably. Thus, it can be inferred that a certain optimum recess number exists, where mixing efficiency becomes the maximum.

• The Journal of Industrial Distribution & Business
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• v.14 no.3
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• pp.19-26
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• 2023

Purpose: There is little emphasis on alternative forms of communication in psychotherapy, thus leaving a gap in research on the impact and effects of alternatives such as using artistic expressions. The current research, therefore, seeks to address the gap by investigating the effect of psychological counseling using Art Therapy on improving workers' job efficiency. Research design, data and methodology: The present author collected topic related to prior studies in terms of psychological counseling, art therapy, and employee job efficiency. And then, the author conducted clear procedure of the screening to eliminate inappropriate previous works including conference papers and dissertations so that this research could obtain only journal articles and books which have been proven by high degree of reliability and validity. Results: This research has concluded that psychological counselling using art therapy is pertinent to improving the worker's job efficiency in various ways, addressing properly mental health issues ranging from small to complicated or acute issues, thus promoting the well-being of employees to work at their optimum or best possible conditions. Conclusions: Psychological counseling using art therapy improves self-confidence, esteem, and awareness. Further, it enhances their social skills, expression capability, and general work ability. Elsewhere it improves coping with pain and reduces stress and depression.

• The Journal of Industrial Distribution & Business
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• v.8 no.5
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• pp.43-52
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• 2017

Purpose - The domestic liquor market is steadily increasing, but locally made liquor markets remain stagnant. The market opening due to the FTA and westernized eating habits are expanding the consumption of imported liquor by Koreans and the demand for beer and soju is still high. Therefore, we analyzed the scale efficiency of Korean locally made liquor companies. Research design, data, and methodology - Based on a translog-cost function, a scale efficiency analysis was conducted using the government's information survey on the liquor industry. Data from 541 liquor companies analyzed from 2013 to 2014 were used for analysis. Results - As a result of the scale efficiency analysis, the average sales of the mid-sized locally made liquor companies is 171 million won, but the appropriate sales amount is 1 million won. It is estimated that there is a need to increase sales. Conclusions - The gap between the actual sales and the appropriate sales of mid-sized locally made liquor companies with 3~10 employees is larger, so it is necessary to reduce the average cost by increasing the sales of locally made liquor companies. In order to do so, it is necessary to acquire customer strategies such as product differentiation, advertising and publicity.

• 한국정보디스플레이학회:학술대회논문집
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• 2005.07a
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• pp.744-747
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• 2005

The exploitable efficiency of UHP is very important in a projection system. We always use lens array for light shaping and energy distribution transformation in conventional projection system. Because of the limitation of arc gap and F/# of elements, the utilize efficiency is always dismal. In this paper we try to bring out a new method to reduce the sparkle formed on the PS converter and enhance the system efficiency.