• 지역연구
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• 제31권1호
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• pp.21-42
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• 2015

본 연구는 도시규모 확장에 따른 최적인구규모를 추정하고 지역간 통행량 분포를 통해 도시규모의 변화를 1기 신도시 건설의 사례를 통해 검증하고자 한다. 이를 위해 수도권 지역의 소득 및 지출함수, 그리고 적정인구수준의 분석과 거리별 통행량 증감에 따른 도시규모 확장과 지역경제 활성화의 가능 여부를 계측하였다. 연구 결과로서 도시규모 확장과 지역경제 활성화는 기종점에 관계없이 통행목적의 기점과 통행량은 반비례 관계에 있음을 추정할 수 있다. 약 20~40km 지점을 전후로 한 지역을 중심으로 통행량이 증가하는 경향이 있는 것으로 도출되었다. 따라서 이 구역을 중심으로 신도시를 건설하는 것이 지리적, 기능적으로 효과적이라고 평가할 수 있다.

• 한국환경과학회지
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• 제24권10호
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• pp.1239-1251
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• 2015

Impervious areas have been expanded by urbanization and the natural structure of water circulation has been destroyed. The limits of centralized management for controlling storm water runoff in urban areas have been suggested. Low impact development (LID) technologies have been promoted as a crucial alternative, establishing a connection with city development plans to build green infrastructures in environmentally friendly cities. Thus, the improvement of water circulation and the control of nonpoint source were simulated through XP-SWMM (storm water and wastewater management model for experts) in this study. The application of multiple LID combination practices with permeable pavements, bioretention cells, and gutter filters were observed as reducing the highest runoff volume by up to 70%. The results from four different LID installation scenarios indicated that permeable paving is the most effective method for reducing storm water runoff. The rate of storm water runoff volume reduced as the rainfall duration extended. Based on the simulation results, each LID facility was designed and constructed in the target area. The LID practices in an urban area enable future studies of the analysis of the criteria, suitable capacity, and cost-efficiency, and proper management methods of various LID techniques.

• 대한산업공학회지
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• 제20권3호
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• pp.151-166
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• 1994

The manufacturing environment on which this research is focused is an FMS in which AGVs are used for material handling and each part type has one or more process plans. The research aims at developing a methodology whereby, given a part and volume mix for production during any production session, the best set of process plans including one plan per part type is selected and the best unidirectional AGV guidepath can be dynamically reconfigured in response to changes in parts and lot sizes combination. For the integrated PPS/FGD problem in which two functions of process plan selection (PPS) and flexible AGV guidepath design (FGD) are integrated, a zero-one integer programming model is developed. The integrated problem is decomposed into two subproblems, process plan selection given a directed AGV layout and AGV guidepath design with a fixed process plan per part type. A heuristic algorithm that alternately and iteratively solves these two subproblems is developed. The effectiveness of the heuristic algorithm is tested by solving various randomly generated sample problems and comparing the heuristic solutions with those obtained by an exact procedure. From the test results, the following conclusions are drawn: 1) For a reasonable size problem, the heuristic is very effective. 2) By integrating the two functions of PPS and FGD, a remarkable benefit in total production time for a given part and volume mix is gained.

• 한국광학회지
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• 제8권4호
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• pp.315-319
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• 1997

광편향은 광굴절결정내의 두 기록빔 간섭에 의해 유도된 동적 광굴절 부피격자를 이용한다. 본 논문에서는 외부 전기장을 인가할 필요가 없으며, 낮은 광세기에서도 쉽게 광굴절 부피격자가 유도되는 CeO$_{2}$가 0.05Wt.% 도핑된 Sr$_{0.6}$Ba$_{0.4}$Nb$_{2}$O$_{6}$(Ce-SBN:60)결정의 동적 특성을 이용하여 광편향기를 구현하고 해석하였다. 그리고, Ce-SBN:60결정의 광파결합특성을 조사하기 위해 2광파 혼합을 통해 결정의 최대결합계수, 유효전하밀도, 기록빔의 세기비에 따른 회절효율 및 회절효율의 시간응답특성을 측정하고 해석하였다.

• Journal of Periodontal and Implant Science
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• 제24권2호
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• pp.271-282
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• 1994

Active treatment of periodontal disease consists of plaque control by the patient, with root planing and surgery perfomed by the dental practitioner. Chlorhexidine rinse has been the most effective antiplaque agent available today and tetracycline has been the most favored antibiotics. Therefore, the purpose of this study was compared the different effect among groups(saline mouthrinse[group I], 0.125% chlorhexidine mouthrinse [groupII], and 0.125% chlorhexidine mouthrinse containing tetracycline[groupIII]) during the immediate post periodontal therapy. We assessed plaque index, gingival index, papillary bleediing index, gingival crevicular volume, periodontal attachment loss, and periodontal pocket depth in 3 sites per subject. The assessment was made at baseline. At 1 week after scaling, and at 2 weeks after curettage. All groups were clinically and statistically reduced plaque score, gingival score, papillary bleeding score, and gingival crevicular volume at 2 weeks after curettage. Group II was significantly reduced periodontal pocket depth.(P<0.05) At 1 week after scaling, al clinical index scores were reduced but not singificantly difference between the groups.(p>0.05) At 2 weeks after curettage, plaque score, gingival score and papillary bleeding score were significantly difference between the groups.(P<0.05) During the experimental period, gingiva was not damaged and stain of the tongue or teeth were not noted in all groups.

• KSBB Journal
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• 제23권3호
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• pp.199-204
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• 2008

Culture conditions for biological hydrogen production were investigated in wastewater of Takju manufacturing factory. Rhodobacter spaeroides KCTC1425, photosynthesis bacteria, and Enterobacter cloacae YJ-1, anaerobic bacteria were used. The hydrogen production were $195.3m{\ell}{\cdot}H_2/{\ell}$ broth for Rhodobacter spaeroides KCTC1425 and $271.8m{\ell}{\cdot}H_2/{\ell}$ broth for Enterobacter cloacae YJ-1 during 36 h. The hydrogen production increased with light intensity, and were highest over 12000Lux. In mixed culture of Rhodobacter spaeroides KCTC1425 and Enterobacter cloacae Y J-1, the optimum mixing ratio of hydrogen production was 20 and 80. Adding volume of yeast extract for maximum hydrogen production was 15 $g/{\ell}$, but there was no effect over that. $Na_2MoO_4$ was most effective among the inorganic salts, and the optimum volume was 0.4 $g/{\ell}$. In semi-continuous culture, total hydrogen production was $13086m{\ell}{\cdot}H_2/{\ell}$ broth for 144 h with operating period of 24 h.

• 대한기계학회논문집B
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• 제31권7호
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• pp.635-643
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• 2007

An inverse radiation analysis is presented for the estimation of the radiation properties for an absorbing, emitting, and scattering media with diffusely emitting and reflecting opaque boundaries. In this study, a repulsive particle swarm optimization(RPSO) algorithm which is a relatively recent heuristic search method is proposed as an effective method for improving the search efficiency for unknown parameters. To verify the performance of the proposed RPSO algorithm, it is compared with a basic particle swarm optimization(PSO) algorithm and a hybrid genetic algorithm(HGA) for the inverse radiation problem with estimating the various radiation properties in a two-dimensional irregular medium when the measured temperatures are given at only four data positions. A finite-volume method is applied to solve the radiative transfer equation of a direct problem to obtain measured temperatures.

• Bioinformatics and Biosystems
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• 제1권1호
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• pp.51-60
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• 2006

The paradigm in biology is currently changing from that of conducting hypothesis-driven individual experiments to that of utilizing the results of a massive data analysis with appropriate computational tools. We present LayMap, an implemented visualization system that helps the user to deal with a high volume of the biomedical literature such as MEDLINE, through the layered maps that are constructed on the results of an information extraction system. LayMap also utilizes filtering and granularity for an enhanced view of the results. Since a biomedical information extraction system gives rise to a focused and effective way of slicing up the data space, the combined use of LayMap with such an information extraction system can help the user to navigate the data space in a speedy and guided manner. As a case study, we have applied the system to datasets of journal abstracts on 'MAPK pathway' and 'bufalin' from MEDLINE. With the proposed visualization, we have successfully rediscovered pathway maps of a reasonable quality for ERK, p38 and JNK. Furthermore, with respect to bufalin, we were able to identify the potentially interesting relation between the Chinese medicine Chan su and apoptosis with a high level of detail.

• Biomolecules & Therapeutics
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• 제13권2호
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• pp.113-117
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• 2005

Organosulfur compounds have been shown to exert an anti-cancer activity. In an attempt to develop novel chemopreventive and anti-cancer agents for liver cancer, we synthesized allylthiopyridazine derivatives. We have previously shown that allylthiopyridazine derivatives exert inhibitory effects on proliferation, invasion and migration of SK-Hep-1 hepatocarcinoma cells in vitro. The in vivo anti-tumor effect of 3-methvl-6-allylthiopy-ridazine, named as K6, was also reported. In this study, we further investigated the preclinical anti-cancer efficacy of K6 for hepatocarcinoma using nude mice xenografted with Hep-G2 hepatocellular carcinoma cells. K6(20-100 mg/kg, orally administered everyday for 30 days) markedly decreased the tumor volume of Hep-G2 cell-transplanted nude mice as evidenced by ultrasonographic and plethysmogranhic analyses. The inhibitory effect on tumor volume was lower than that exerted by doxorubicin (2 mg/kg), intravenously injected) which was used as a positive control. This study shows that K6 efficiently suppresses xenograft tumor growth, revealing K6 as apotential anti-cancer agent for suppressing in vivo progression of liver cancer. Given that hepatocarcinoma is among the most prevalent and lethal malignancies and there is no effective treatment to date, our study may contribute to the potential drug development for liver cancer.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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• pp.22-25
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• 2005

The 10 Year Implementation Plan for a Global Earth Observation System of Systems (GEOSS), which was endorsed at the Third Earth Observation Summit in Brussels in February, 2005, emphasizes the importance of data management facilities for diverse and large-volume Earth Observation data from inhomogeneous information sources. A three year research plan for addressing this key target of GEOSS has just approved as the first step by the Japanese government. The goals of this research are, (1) to develop a data management core system consisting of data integration and information fusion functions and interoperability and information service functions; (2) to establish data and information flows between data providers and users; (3) to promote application studies of data integration and information fusion, especially in the fields of weather forecasting, flood forecasting, agricultural management, and climate variability and changes. The research group involves leading scientists on information science and technology, who have been developing giant data archive servers, storage area networks, metadata models, ontology for the earth observations. They are closely cooperating with scientists on earth sciences, water resources management, and agriculture, and establishing an effective collaborative research framework.