• 제목/요약/키워드: Effective Way

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Novel 99mTc(CO)3 Complexes with WAY-100635 Moiety for the Development of 5-HT1A Receptor lmaging Agent

  • Choi, Kang-Hyuk;Pyun, Mi-Sun;Hong, Young-Don;Choi, Sun-ju
    • Bulletin of the Korean Chemical Society
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    • 제30권5호
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    • pp.1107-1112
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    • 2009
  • The aim of this study is to develop and synthesize $5-HT_{1A}$ receptor imaging agents with WAY-100635 moiety and $^{99m}Tc(CO)_3$ core. WAY-100635 is commonly known as $5-HT_{1A}$ antagonist and its labeled compound ([$^{11}C$] WAY-100635) has been used as effective radioligand for imaging brain $5-HT_{1A}$ receptors with PET(Positron Emission Tomography). However, there are several restrictions in using a radioisotope of C-11 and requires for more effective radioisotopes and ligands. In order to produce a structure most similar to WAY-100635, WAY-100635 derivatives containing a cysteine chelator were designed and confirmed by using in silico (Hyperchem). The novel compounds (7a, 7b, 7c) were prepared in five or 7 steps with yields of 16%, 36% and 42%, respectively and radiolabeled with $[^{99m}Tc(CO)_3(H_2O)_3]^{+}$. The labeling yield was 99% for all the newly synthesized compounds. [$^{99m}Tc(CO)_3$]- WAY-100635 derivatives show a neutral charge which were confirmed by paper electrophoresis.

Energy Saving Effect and Economy Feasibility of Office Building with regard to Geometries and Orientations

  • Koh, Jae-Yoon;Zhai, John
    • International Journal of Air-Conditioning and Refrigeration
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    • 제17권1호
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    • pp.15-24
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    • 2009
  • The energy usage and the economical feasibility of the typical two story office building in the three urban locations of South Korea are evaluated as the eight orientations. The smallest energy consume is shown at the true south. The ranges of the low energy consume are $-3l5^{\circ}{\sim}0^{\circ}\;and\;-135^{\circ}{\sim}-180^{\circ}$. There are obvious advantages of passive solar designs such as using a fully glazed facade at the true south in the building. The General Low voltage plan is the effective way for the office building when does not required the high voltage electricity. The energy cost of KEPCO is compared to that of XCEL ENERGY. The portion of the customer charge of XCEL ENERGY is about 10% but it is about 50% of the total tariff of KEPCO. The effective way to save the energy cost is by reducing the operating energy of XCEL ENERGY plane but the most effective way is reduce the contracting energy of KEPCO plane.

비슬산 진달래군락지의 생육활성화 방안 (Management Methods on the Growth Activation of Rhododendron mucronulatum Habitat in Mt. Biseul)

  • 박인환;조광진
    • 한국환경복원기술학회지
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    • 제16권2호
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    • pp.105-114
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    • 2013
  • This study was carried out to find growth increasing methods of Rhododendron mucronulatum in Mt. Biseul. 4 treatments(heavy pruning, light pruning, non-pruning+fertilization, non-pruning(control)) were used in the study area with different pruning methods. Growth characteristics of new shoot, number of creation of flower buds and leaf buds in new shoot were analysed. Significant differences were observed among the treatments and stem diameter degree. Diameter, length of new shoots and the number of flower buds, leaf buds per new shoots increased in the pruning treatments. But heavy pruning showed more effective growth increasing way than light pruning. Non-pruning and fertilization treatments were not effective to increase growth of Rhododendron mucronulatum. And pruning at the end of May was the most effective way for growth of new shoot.

산업재해 예방을 위한 효과적 안전교육방안 연구 - 인천지역 중소기업을 대상으로 - (A Study on the Effective Safety Education Plan to Prevent Industrial Disaster - Focused on to small and medium enterprises in Incheon area -)

  • 이백현;정수일
    • 대한안전경영과학회지
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    • 제9권2호
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    • pp.19-31
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    • 2007
  • If you examine the Industrial Disaster Analysis Content that occurs every year in the small and medium enterprise, industrial disaster occurs because of manager's lack of safety and worker's unprepared safety education. Therefore effective safety education systems are needed to offer adequate knowledge and technology to the workers. On this research, to give an effective education way to decrease industrial disaster we administered to the workers who are in charge of 300 workplace in Incheon area to search actual condition of industrial disaster and to disclose a link between industrial disaster and industrial safety education. We put in effect on frequency study and examined x2 using SPSSWIN 10.0. On the research, the results shows that the industrial safety education and training are in effect regularly and the satisfaction are low. But the manager's satisfactions are high through safety education. So it shows that we need to find a way to put in effect safety education to satisfy the workers.

Effects of Voluntary Tutoring and Mandatory Tutoring on Academic Performance

  • Eun Hye KWON;John SMITH;Sukho LEE
    • Journal of Sport and Applied Science
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    • 제7권3호
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    • pp.27-35
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    • 2023
  • Purpose: Providing tutoring services may be one of the most effective practices for improving academic performance and student retention. However, there is little information on the difference between mandatory tutoring (MT) and voluntary tutoring (VT) on the impact of student academic performance. This investigation compared the effectiveness of VT and MT services in the three upper level undergraduate classes. Research design, data, and methodology: Baseline data were collected in a spring semester where no tutoring of any kind was offered (control group (CG), n=78). The MT (n=104) was required in the following fall semester, and in the next spring semester only VT (n=97) was offered. Descriptive statistics and One-way ANOVA using IBM SPSS v23 (Chicago, IL) were used to analyze the final grades of the courses to identify differences in final grades between semesters. Results: Although final grades averaged from three classes were highest in the MT group, there were no statistical differences between the MT and VT groups, F(2, 292) = 1.150, p =.318. Conclusion: This study indicates there was no significant difference in academic performance between the two tutoring types, but that both tutoring services can be effective.

An effective stiffness model for RC flexural members

  • Balevicius, Robertas
    • Structural Engineering and Mechanics
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    • 제24권5호
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    • pp.601-620
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    • 2006
  • The paper presents an effective stiffness model for deformational analysis of reinforced concrete cracked members in bending throughout the short-term loading up to the near failure. The method generally involves the analytical derivation of an effective moment of inertia based on the smeared crack technique. The method, in a simplified way, enables us to take into account the non linear properties of concrete, the effects of cracking and tension stiffening. A statistical analysis has shown that proposed technique is of adequate accuracy of calculated and experimental deflections data provided for beams with small, average and normal reinforcement ratios.

부분부하와 무부하에서의 가변 배기량기관의 성능특성 (Performance Characteristics of a Variable Displacement Engine at Part-Load and Idle)

  • 한성빈;이성열
    • 대한기계학회논문집
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    • 제18권1호
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    • pp.232-239
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    • 1994
  • This paper presents an effective way of improving fuel consumption for a variable displacement engine. The improvement of fuel consumption can be accomplished by means of deactivating inlet and exhaust valves, reducing the number of effective cylinders of a four-cylinder gasoline engine that is mounted on a domestic compact automobile.

Improved Method of Characteristics for Two way Subscriber Transmission Systems

  • Phetsomphou, Douangsamone;Tsuchiya, Naosuke;Tanaka, Kimio
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2004년도 ICCAS
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    • pp.1355-1359
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    • 2004
  • The two way subscriber transmission systems have tendency to spread its carrier frequency bandwidth or information bit rate and average bit error rate according to popularization of high speed information through the digital communication system, transmission medium and the Internet. This fact is an important incentive to realize new systems. These two way subscriber transmission systems usually use same cable or same carrier frequency bandwidth for up stream channel and down stream channel. In the systems, the disturbances of noise, crosstalk or fading affect the characteristics. Specifically, these disturbances cause the decrease of information bit rate and degradation of transmission quality. This paper proposes the improved method of their degradations using the particular feature of two way subscriber transmission systems and it makes clear proposed method is effective by theoretically and some numerical examples.

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변형된 삼원촉매에 의한 저온시동조건에서의 메탄올엔진 배가스 정화효과에 관한 연구 (Studies on the Emission control of methanol engine exhaust with modified 3-way catalyst at cold start condition)

  • 홍종성;정석진
    • 한국대기환경학회지
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    • 제9권2호
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    • pp.160-167
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    • 1993
  • As the major methanol fueled vehicle exhaust components, formaldehyde & methanol conversion over the existing commercial 3-way catalyst was examined in a labolatory tains different Ag loadings on commercial 3-way catalyst, and german commercial catalysts for methanol engine exhaust manufactured by a commercial manufacturer. Silver catalysts were prepared by the wet impregnation of silver nitrate solution on commercial 3-way catalyst. These catalysts were characterized with BET Surface area and pore size distribution. In general, the formaldehyde(HCHO) conversion of the tested catalysts was similar to that of methanol$(CH_3OH)$. At 100$^\circ$C, which is equivalent to the cold start condition, 5wt% Ag cat. showed the most excellent HCHO and $CH_3OH$ conversion. The order of activity for conversion of HCHO & $CH_3OH$ to carbon dioxide and water vapor was as follows ; 5wt% Ag/3-way cat.>2wt% Ag/3-way cat.>german cat. front(1) > german cat. rear(2) > 10wt% Ag/3-way cat.> commercial 3-wat catalyst. However there was no significant activity difference between those tested catalysts in the hot run condition of 400$^\circ$C. Therefore, it could be concluded that the Ag-modified 3-way catalyst was the most effective and practical catalyst system which could be capable of removal the HCHO and methanol at the special condition of low temperature such as cold start condition.

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