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Famine exposure in early life and type 2 diabetes in adulthood: findings from prospective studies in China

  • Feng Ning ;Jing Zhao ;Lei Zhang ;Weijing Wang ;Xiaohui Sun ;Xin Song ;Yanlei Zhang ;Hualei Xin ;Weiguo Gao;Ruqin Gao ;Dongfeng Zhang ;Zengchang Pang
    • Nutrition Research and Practice
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    • v.17 no.4
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    • pp.780-788
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    • 2023
  • BACKGROUND/OBJECTIVES: This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959-1961 Chinese Famine. SUBJECTS/METHODS: A total of 3,418 individuals aged 35-74 years free of diabetes from two studies in 2006 and 2009 were followed up prospectively in 2009 and 2012, respectively. Famine exposure was classified as unexposed (individuals born in 1962-1978), fetal exposed (individuals born in 1959-1961), child exposed (individuals born in 1949-1958), and adolescent/adult exposed (born in 1931-1948). A logistic regression model was used to assess the relationship between famine exposure and diabetes after adjustment for potential covariates. RESULTS: During a three-year follow-up, the age-adjusted incidence rates of type 2 diabetes were 5.7%, 14.5%, 12.7%, and 17.8% in unexposed, fetal-exposed, child-exposed, and adolescent/adult-exposed groups, respectively (P < 0.01). Relative to the unexposed group, the relative risks (95% confidence interval) for diabetes were 2.15 (1.29-3.60), 1.53 (0.93-2.51), and 1.65 (0.75-3.63) in the fetal-exposed, child-exposed, and adolescent/adult-exposed groups, after controlling for potential covariates. The interactions between famine exposure and obesity, education level, and family history of diabetes were not observed, except for the urbanization type. Individuals living in rural areas with fetal and childhood famine exposure were at a higher risk of type 2 diabetes, with relative risks of 8.79 (1.82-42.54) and 2.33 (1.17-4.65), respectively. CONCLUSIONS: These findings indicate that famine exposure in early life is an independent predictor of type 2 diabetes, particularly in women. Early identification and intervention may help prevent diabetes in later life.

Individual Exposure Characteristics according to the Humidifier Disinfectant Exposure Assessment Cycle - Focusing on Cycles I-to-V Applicants - (가습기살균제 피해구제 신청자들의 신청 차수별 노출 특성 변화 - 1차에서 5차 신청자를 중심으로 -)

  • Seula Lee;Eun-Kyung Jo;Habyeong Kang;Wonho Yang;Yoon-Hyeong Choi
    • Journal of Environmental Health Sciences
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    • v.49 no.3
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    • pp.159-168
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    • 2023
  • Background: An ongoing environmental exposure assessment of humidifier disinfectants (HDs) has been conducted since November 2011 among individuals who experienced HD exposure-related adverse health effects. It is being performed in order to determine and quantify exposure to humidifier disinfectants in victims and their families. To date, the assessment has encompassed Cycles I-to-V. There is no report summarizing the characteristics of the subjects from the overall cycles. Objectives: We intended to examine the individual characteristics related to demographics, HD usage, and HD exposure using integrated data from Cycles I-to-V of the environmental exposure assessment of HDs and the changes with the cycles. Methods: We included 7,543 individuals who participated in Cycles I-to-V of the environmental exposure assessment of HDs. We summarized the participants' characteristics regarding their demographics (e.g., sex, education level, and age), HD usage history (e.g., product name, ingredient, and frequency of HD use), and HD exposure (e.g., daily time of HD use, cumulative time of HD use, and exposure intensity). In addition, their characteristics were compared across the cycles of the exposure assessment. Results: Among the 7,543 participants from Cycles I-to-V, there were more male participants than females (51.05% overall), except for Cycles I and III. Across all cycles, a higher proportion of survivors was observed than deceased individuals. While PHMG was the most prevalent ingredient in HDs throughout all the cycles, its proportion gradually decreased over the course of the examination cycles. Participants in Cycle I reported longer daily times of HD use compared to those in the subsequent cycles. On the other hand, cumulative time of HD use was shorter in the earlier cycles than in the later cycles. Conclusions: Using the integrated data from the full cycles of the environmental exposure assessment, this study identified changes in demographic characteristics as well as the HD exposure characteristics between the participants across different cycles.

An Investigation on Employment Effect of Senior Job Training (준·고령자 직업훈련의 훈련생 및 훈련 특성이 재고용에 미치는 효과)

  • Lee, Kyung Hee;Lee, Yohaeng
    • 한국노년학
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    • v.31 no.3
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    • pp.527-538
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    • 2011
  • The purpose of this investigation is to analyze the effect of employment and quality of employment of senior job training. The questionnaire administered to 576 senior job trainees(over 50 years old) and 28 training institute before and after job training to survey job training characteristics, training institute characteristics and trainee characteristics. The results were as follows : First, independence test(X2) revealed that occupational category, period of training, type of institution, training history, location, and trainee's education level had significant difference on employment. Second, The probability of employment was higher in new and well-equipped public institution than private or old public institution. Third, compared with the prior wage, the wage after training decreased. This result suggested that the unemployed senior can hardly be reemployed in prior level job. The result of analysis on the cases of increased wage after training revealed that the trainees who was women, had a little dependent family, a shorter unemployed period, and a higher prior wage showed higher wage than prior wage after training.

A study of the Life-Course perspective - The exploratory analysis of Transitions to adulthood - (생애과정 관점에 대한 고찰과 적용 - 성인으로의 이행과정에 대한 탐색적 분석 -)

  • Moon, Hey jin
    • Korean Journal of Social Welfare Studies
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    • v.41 no.3
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    • pp.349-378
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    • 2010
  • The Life-Course perspective is a theoretical orientation that views the life-course as the age structure embedded in social institutions and history and understands the life-course of individual and group in the contextual perspective. The life-course perspective studies were developed in Germany and North America. They study social and historical effects and the effect of institutions and the state on the life-course, the pathway of the work career and differences of labour outcomes, and the inequality that is developed in the life-course. In Korea, the life-course perspective studies were tried in various fields and cumulated. However, it didn't established as a theoretical orientation. For applying the life-course perspective to connect the individual life-course with social and historical event, I describe the historical location of individuals born between 1930 and 1979 and analyse the change of their transitions to adulthood exploratorily. On results, the extension of education made the structural change of their life-course, and in young cohort the timing of leaving school, entering workforce, marriage and childbirth was delayed and transitions were made in narrower spread. It means the standardization of the life-course as appears in modern society. The 1970s birth cohort has the differenciated life-course pattern, however I cannot verify that change because of the right censoring.

A Case Study of the Utilization of Cultural Property in Border Areas led by Local Residents - Focusing on the Horogoru Tong-il Balagi Festival in Wondang-ri, Jangnam-myeon, Yeoncheon-gun - (지역 주민주도를 통한 접경지역 문화유산 활용사례에 관한 연구 - 연천군 장남면 원당리 호로고루 통일바라기 축제를 중심으로 -)

  • LEE Sejin;PARK Kyujin;CHOI Jongtaik;LEE Donghae;KANG Sangsik
    • Korean Journal of Heritage: History & Science
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    • v.56 no.4
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    • pp.270-286
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    • 2023
  • This article is about the conservation and use cases of Horogoru, a Goguryeo site located in Wondang-ri, Jangnam-myeon, Yeoncheon-gun in Gyoenggi Province. After Horogoru was excavated, it was decided to build a park around it as a way to prevent damage, and also to plant sunflowers to symbolize the sun. Naming the park 'Tong-il Balagi Park', which refers to the wish for unification, local residents and other related organizations jointly opened the site. Afterwards, they looked for ways to utilize the location and park, and chose to hold the 'Tong-il Balagi Festival'. The festival is an event held under the leadership of local residents, which has the effect of promoting both conservation and cultural property, as well as generating economic benefits. In other words, the Yeoncheon-gun, Jangnam-myeon Tong-il Balagi Festival can be said to be an exemplary example of successfully overcoming various disadvantages associated with the border area near the ceasefire line through local residents' own utilization of cultural property.

Efforts to Improve the E-Learning Center of the Korean Society of Radiology: Survey on User Experience and Satisfaction (대한영상의학회 이러닝 센터 발전을 위한 노력: 대한영상의학회 회원 설문조사)

  • Yong Eun Chung;Hyun Cheol Kim
    • Journal of the Korean Society of Radiology
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    • v.83 no.6
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    • pp.1259-1272
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    • 2022
  • Purpose As part of ongoing efforts to improve the current e-learning center, a survey was conducted regarding user experience and satisfaction to identify areas of improvement. Materials and Methods Radiologists (n = 454/617) and radiology residents (n = 163/617) of the Korean Society of Radiology were asked to answer a survey via email. The questionnaire asked for basic user information as well as user experiences relating to the e-learning center, such as workplace, frequency of use, overall satisfaction levels, reasons for satisfaction or dissatisfaction, and other suggestions for improvement. Results Annual members and all members of the e-learning center reported above average satisfaction levels of 67% and 42%, respectively. Approximately 30% of respondents viewed e-learning center lectures more than 5 times a month, with residents having a particularly high usage frequency. There was a high demand for additional lectures covering more diverse specialties (e-learning for annual members only: n = 28/97, e-learning for all members: n = 72/166), a smoother and more convenient searching platform/interface (n = 37/97 and n = 58/166, respectively), and regular content updates. In addition, many of the members suggested the addition of user-friendly functions such as playback speed control, a way to save viewing history, as well as requests for improved system stability. Conclusion Based on survey results, the educational committee plans to continue its efforts to improve the e-learning center by increasing the quality and quantity of available lectures, and increasing technical support to improve the stability and convenience of the e-learning digital system.

A Study on Prescription and Management of Medicines by School-Nurses (양호교사(養護敎師)의 투약(投藥) 및 의약품관리(醫藥品管理) 실태(實態))

  • Kim, Jung Hee;Park, Jae Yong;Cha, Byung Jun
    • Journal of the Korean Society of School Health
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    • v.11 no.2
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    • pp.297-307
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    • 1998
  • The purpose of this paper is to understand the prescription and management of medicines by school-nurses. A survey was mailed to 199 school-nurses in elementary and secondary schools in Pusan from February 10 to March 31, 1997. It was shown that 97.0% of the schools have visiting school-doctors and only 29.6% have visiting school-pharmacists. 36.7% of the respondents don't know the amount of this annual health-related budget. Concerning the annual budget of purchasing medicines, 50.4% of the elementary schools spend 210,000 won to 400,000 won and 45.0% of the secondary schools spend more than 610,000 won. 56.3% of the respondents said the budget was enough, but 5% said it was not. 70.9% of the schools purchase medicines twice a year. The average number of students visiting the nurse in a year are 1,892 in elementary schools, 1.6 times per student and 2,471 in secondary schools, 1.7 times per student, respectively. The annual average number of students who were prescribed medicine a year are 1,804 in elementary schools, 1.5 times per student, 2,372 in secondary schools, 1.7 times per student. The percentage of students who are prescribed internal medicines was 45.5% in elementary, schools and 61.3% in secondary schools, respectively. To the preralence sicknesses, the wound was the most common, accounting for 42.7% in elementary and 22.6% in secondary schools. Next was abdominal pain, indigestion, and headaches in elementary schools; and colds, indigestion, and abdominal pain in secondary schools, respectively. To the dirersity of medicines prescribed: internal medicines 29 for abdominal pain, 25 for indigestion, 8 for physiological pain, 13 for headaches, 30 for colds, and 10 for eye disease; external medicines 2 for skin disease, 10 for toothaches and 31 for other sicknesses. 42.7% of the respondents said the schools have enough medicines, but 7.6% said that schools need more. 50.8% of the respondents said they get information on medicines from TV advertisements or medicine-related books, 16.6% get information from visiting pharmacists. More experienced nurse-teachers are likely to get information from visiting pharmacists, but 37.5% of the respondents who have less then four year experience in school get information through other nurse-teachers before deciding to buy medicines. To the choice of medicines: 83.9% of the respondents said that they choose safe medicines with less side-effects. 40.7% responded that they write down the prescription history daily, but 6.1% said they do this only once in two or three months. To the confidence in prescriptions, 37.7% of the respondents said they are sure of the effectiveness of the medicines they prescribe. To what extent the nurse-teachers prescribe, 50.3% said they prescribe to the level of anagelics, and 21.1% prescribe to anti-histamines and antibiotics. 80.4% said that the details of illnesses and medicines to be prescribed in school should be regulated by a school health-care law. To the problems in prescription, 79.9% of the respondents worry about abuse by students who want prescriptions but have no serious illnesses, 57.8% worrg about the lack of information on medicines and dosage. And 55.8% said they can't tell the difference between medicines whose brands are different, but bare the same ingredients. The conclusion of this study is that a health education program is necessary to prevent the misuse or abuse by students and a continuing education program for school-nurses is needed to solve the problems related to the purchasing and prescription of medicines. The criteria of the prescription of medicines also should be regulated by a school health-care law or management acts.

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Research on the Improvement of the Law of Record Management (기록관리법의 개정과 관련한 제문제 연구)

  • Kim, Sung-Soo
    • Journal of Korean Society of Archives and Records Management
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    • v.4 no.2
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    • pp.41-75
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    • 2004
  • This research discusses how to improve the current environment for record management in relation to the Revision of the Law of Record Management in South Korea. Three major issues are: 1) Legal status of the National Archives & Records Service of Korea as the government institution in charge of managing centrally records, 2) System for the education and training of professionals who specialize in record management, and 3) Foundation of the national museum and archives of records. Findings are as follows: First, the existing 'National Office of Records' as the government institution in charge of managing records, should be promoted to the 'National Archives & Records Service of Korea' in order to be administered by the class of a vice-minister in the Ministry of Government Administration and Home Affairs. Second, the qualification criteria which currently requires the Master's degree of Record Management, should be modified to include the Bachelor's degree in the field in order to expand the pool of professional human resources. Also, to hire the public officials for record management, either the positions of 'researcher/record manager group' should be created, or the existing positions of librarian, archivist, and record manager should be integrated into the new position of 'record culture group'. Third, the most significant task for the office of record management of local governments is to inherit and further develop the traditional culture and documentary legacy which are unique to those local communities and governments at various levels, and a priority should be given to those tasks. Therefore, when the Law of Record Management will be later revised, the establishment of the office of record management for local governments at every level should be required, and the museum and archives of records should be also established as a significant part of the institution. Unique local culture and history of particular communities should be collected and preserved in systematically specialized and differentiated ways in those institutions of record management, and the names should be uniquely given to the institutions according to the characteristics of local governments.

Reproduction Cycle and Litter Size of Red-tongued viper snake (Gloydius ussuriensis) (쇠살모사의 생식주기와 한배의 출산수)

  • Kim, Byoung-Soo;Oh, Hong-Shik
    • Korean Journal of Environment and Ecology
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    • v.28 no.5
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    • pp.531-541
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    • 2014
  • This research investigated the reproduction cycle, litter size, and the effects of factors of red-tongue viper snake inhabiting in Jeju Island, to delve into their life strategy. Field survey was conducted in Jeju Island from May 2006 to November 2008. Reproduction cycle was analyzed through measurements of testis and follicle sizes in laboratory from March 2009 to December 2010. According to the research results, the sizes of red-tongue viper snake's testis and follicle clearly changed seasonally. The number of eggs within the oviduct were greater on the right side ($2.6{\pm}1.0$ eggs, n=16) than on the left side ($1.8{\pm}0.5$ eggs, n=16) (t=-2,721, p<0.05). Average (${\pm}SD$) of survival litter size (SLS) was $4.4{\pm}1.7$ (1~9, range), while total litter size (TLS) was $4.7{\pm}1.5$ (3~9, range), which were not statistically significant. However, their litter sizes were similar to the number of eggs within the oviduct (t=0.039, P>0.05). Relative litter mass (RCM) was $0.42{\pm}0.13$ (0.18~0.79, n=33), and tended to increase, as maternal condition of pre-parturition (MCPPI) was getting better. The sexual ratio of delivered litters showed no significant difference between male and female red-tongue viper snakes (♂:♀ = 1.15:1, n=73 ; ${\chi}^2$=0.342, P>0.5). Average neonate mass showed a weak correlation with maternal mass of pre-parturition (MMPP1) (r=0.387, P<0.05, n=33). Average neonate Snout-vent length (SVL) also demonstrated a weak correlations with maternal SVL (r=0.399, P<0.05, n=33) and MMPP1 (r=0.344, P<0.05, n=33). Average neonate mass and maternal SVL approached significant probability (r=0.323, P=0.067, n=33). This indicates that mother snakes can bear bigger litter due to its larger size. In some cases, litter's weight decreases as mother snakes are bearing more litter; however, the red-tongued viper snake did not show such exchange relationship. From this, it can be conjectured that a red-tongued viper snake has peculiarity of its own species. The research results are predicted to be used as the basis to find a life history of red-tongued viper snake.

Exploration of Features of Korean Eighth Grade Students' Achievement and Curriculum Matching in TIMSS 2015 Earth Science (TIMSS 2015 중학교 2학년 지구과학 영역에 대한 우리나라 학생들의 성취 특성 및 교육과정 연계성 탐색)

  • Kwak, Youngsun
    • Journal of The Korean Association For Science Education
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    • v.37 no.1
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    • pp.9-16
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    • 2017
  • The result of TIMSS 2015 was announced at the end of 2016. In this research, we conducted test-curriculum matching analysis for 8th grade earth science and analyzed Korean students' percentage of correct answers and responses for TIMSS earth science test items. According to the results, Korean students showed high percentage of correct answers when the item topics are covered in the 2009 revised science curriculum, and Korean students revealed their weakness in constructed response items since the percentage for correct answers on constructed response items is half that of multiple choice items. Depending on the earth science topic, for 'solid earth' area, which includes earth's structure and physical features, as well as earth's processes and history, students showed high percentage of correct answers for multiple choice items. Students, however, showed low percentage of correct answers for items that require applying knowledge to everyday situations and connecting with other areas of science such as biology. For 'atmosphere and ocean' areas, which include earth's processes and cycles, students showed low percentage of scores for climate comparison between regions, features of global warming, etc. For the area of 'universe', students showed high percentage of scores for the earth's rotation and revolution, the moon's gravity, and so on because they have learned these topics since primary school. Discussed in the conclusion are ways to secure content connection between the primary and middle school earth science curriculums, ways to develop students' science-inquiry related competencies, and so on to improve middle school earth science curriculum as well as teaching and learning.