• Title/Summary/Keyword: Economic efficacy

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Relationship Self-control, Stress, Loneliness among University Students (대학생의 자기통제력, 스트레스, 외로움 및 자살시도의 상관관계)

  • Lee, Young-Mee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.12
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    • pp.5541-5549
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    • 2011
  • The purpose of this study was to investigate the relationship self-control, stress, loneliness among University Students, to provide the basic data for prevention of suicide occurrence. Methods: The subjects of this study were 1,253 university students. The collected data was analyzed using descriptive statistics, $x^2$-test, t-test, Pearson correlation coefficient and stepwise multiple regression with SPSS 17.0 Program. Results: The degree of the suicide attempt was 13.6%. The reported scores for self-control, internet addiction, stress, self-efficacy, anxiety, loneliness were 69.9, 42.5, 86.4, 48.2, 46.2, 40.1, respectively. The degree of suicide attempt was significantly different according gender, religion, parents status, family economic status, living, friendship, exercise, alcohol drinking, loneliness, state anxiety, stress, self-control, and internet addiction. The influential factors affecting suicide attempt were parents status, internet addiction, gender, exercise, and loneliness, which explained about 5.5% of the variance. Conclusions: These result suggest that earlier screening and suicide prevention programs for university students will be helpful in preventing suicide attempt. Future studies need to be pursued to find various variances for suicide attempt for university students.

Efficacy of Flaxseed Flour as Bind Enhancing Agent on the Quality of Extended Restructured Mutton Chops

  • Sharma, Heena;Sharma, Brahma Deo;Mendiratta, S.K.;Talukder, Suman;Ramasamy, Giriprasad
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.2
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    • pp.247-255
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    • 2014
  • Consumers have become very conscious about their nutrition and well being due to changes in their socio-economic lifestyle and rapid urbanization. Therefore, development of technology for production of low cost and functional meat products is urgently required. One such approach is innovative restructuring technology in which binding of meat pieces still remains the main challenge and extension of product is generally associated with poor binding and texture. Thus, the present study was envisaged as an attempt to solve this problem by the incorporation of flaxseed flour (FF) as bind enhancing agent. The FF was used at three different levels viz., 0.5%, 1%, and 1.5% to replace lean meat in pre-standardized restructured mutton chops formulation. The products were subjected to analysis for physico-chemical, sensory and textural properties. Cooking yield, moisture percentage and fat percentage increased with increase in the level of incorporation of FF, however, protein percent and pH decreased with increase in the level of incorporation. Shear force value of product incorporated with 1.5% FF was significantly higher (p<0.01) than control and product containing 0.5% FF level. Among the sensory attributes, product with 1% flaxseed flour showed significantly higher values (p<0.05) for general appearance, binding, texture and overall acceptability. Hardness showed significant increasing (p<0.01) values with increasing levels of incorporation of flaxseed flour, however all other parameters of texture profile analysis showed a decreasing trend. On the basis of sensory scores and physico-chemical properties, the optimum incorporation level of FF was adjudged as 1%. Products incorporated with optimum level of flaxseed flour (1%) were also assessed for water activity and microbiological quality during the storage period of 15 days. It was found that the extended restructured product could be safely stored under refrigeration ($4^{\circ}C{\pm}1^{\circ}C$) in low density polyethylene (LDPE) pouches for 15 days without marked deterioration in sensory and microbiological quality. Thus, it was concluded that flaxseed flour can be used as a good bind enhancing agent in extended restructured meat products at an economic cost.

Mineral Medicine Described in the Oriental Medicine Book and Mineral Medicines Applicable to Atopic Dermatitis Treatment (한의서에 기재된 광물(鑛物) 약재 및 아토피피부염 활용 외용성 광물(鑛物) 약재)

  • Bak, Jiwon;Kim, Donghee
    • Economic and Environmental Geology
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    • v.48 no.3
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    • pp.231-240
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    • 2015
  • A total of 93 mineral medicines are mentioned in the Chinese Bonchodogam(本草圖鑑). In Donguibogam(東醫寶鑑), 77 mineral medicines are listed, where 18 are from soil origin, 4 from gem origin, and 55 mineral medicines were originated from stone. In the Herblogy(本草學), which is the textbook used in most oriental medicine colleges in Korea, a total of 23 mineral medicines are listed. Of those, Cinnabaris, Alumen, Melanteritum, Realgar, Orpimentum, Sulfur, Lime from Donguibogam, additional eight which are Talcum, Calomelas, Minium, Calamina, Stannum, Hydrargyrum, Lithargyrum, Hydrargyrum Chloratum from Bonchodogam and Gypsum, Natrii Sulfas, Talcum, Cinnabaris, Sulfur, Arsenicum Sublimatum, Realgar, Calomelas, Minium, Calamina, Borax, Aurum, Glauberitum from Herblogy were selected as the mineral medicine applicable as external atopic dermatitis treatment. Most of the mineral medicines were generally regarded as toxic materials, and therefore, they were elaborately processed to remove toxicity before use. In accordance, it is necessary to discuss how to effectively remove toxicity from toxic mineral medicines. In addition, detoxification can be applied to those mineral medicines classified based on the index material or high content compounds, and if efficacy can be evaluated through various analytical methods, this can be applied to diverse inflammatory diseases as well as atopic dermatitis.

Standardization Studies for the Oriental Mineral Medicine (광물성 약재(광물약)의 표준화에 관한 연구)

  • Kim, Seon-Ok;Park, Maeng-Eon
    • Economic and Environmental Geology
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    • v.48 no.3
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    • pp.187-197
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    • 2015
  • Oriental mineral medicines are single or mixture of more than one mineral species or rock/fossil which are used to treat disease. Mineral medicines remove harmful or useless substances to decrease toxicity and secondary effects, and cause the manufacture of medical compounds with increased efficacy. The extraction test is an accepted in vitro system to predict the bioaccessibility of major and minor elements from mineral medicine. It incorporates gastrointerstinal tract parameters representative of a human body that including stomach and small intestinal pH which are the same as digestion condition. The bioaccessibility of a mineral medicine is the fraction that is soluble in the gastrointestinal environment and is available for absorption. Reaction path modeling in the human body can predict digestion with gastric fluid as well as absorption in the small intestine, existence in body fluids and reaction progress of the exhaust process according to pH conditions in body. Also reaction path modeling can predict bioavailability, which is equal to existence rate in the body and the form and amount of a medicine in the body after intake. The study results from predicating the existence form mineral medicines in the body, and proving the effective ingredient using bioaccessibitily and human risk assessment, suggest these that should be necessary data for new medicine development.

The introduction of Traffic Inducement Security System in Korea - Centering on Curriculums - (한국의 교통유도경비 도입방안 -교과과정을 중심으로-)

  • Lee, Sang-Won;Lee,, Seung-Chal
    • Korean Security Journal
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    • no.25
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    • pp.147-164
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    • 2010
  • A variety of work zone including road single-sharing construction add surrounding disorder and increase inconvenience of vehicles and pedestrians and furthermore danger of traffic accidents, which sometimes result in human life damages. Traffic delay due to vehicles and users generating in the course of using large-scale multiplex facilities bring about a great economic loss. Now, a lot of regulations and laws related to traffic safety system on construction sites etc. are established, but can not display efficacy desirably. It brings about continuous economic loss due to human life accidents and delay. For the purpose of solving the problems, it is necessary to import systems such as traffic inducement Security (Japan) and traffic controller (CANADA, USA) This article suggest how improve civil safety and reduce Social cost. therefore This thesis aims at analyzing advanced cases of foreign countries, looking into Korean status, and presenting importing ways of traffic inducement Security appropriate to Korea. It is reasonable to grant grade1, grade2, and technical experts to traffic inducement Security who pass regulated educations and examinations. In addition, by reversing regulations and laws, it is necessary only those who have the licenses of traffic induction guarder etc. can establish construction sites and disordered places on roads. Theory educations for education time must include basic educations and expert educations. Basic educations must include understanding regulations and laws and understanding affairs. Expert educations must include traffic control, safety educations, understanding of traffic accidents, operation of traffic control facilities, and traffic accident settlements. Traffic affairs educations must include traffic induction affairs in sites (hand signals, safety material establishment, traffic accident settlements, and urgent treatments).

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Cost Effectiveness Analysis of Different Management Strategies between Best Supportive Care and Second-line Chemotherapy for Platinum-resistant or Refractory Ovarian Cancer

  • Luealon, Phanida;Khempech, Nipon;Vasuratna, Apichai;Hanvoravongchai, Piya;Havanond, Piyalamporn
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.2
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    • pp.799-805
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    • 2016
  • Background: There is no standard treatment for patients with platinum-resistant or refractory epithelial ovarian cancer. Single agent chemotherapies have evidence of more efficacy and less toxicity than combination therapy. Most are very expensive, with appreciable toxicity and minimal survival. Since it is difficult to make comparison between outcomes, economic analysis of single-agent chemotherapy regimens and best supportive care may help to make decisions about an appropriate management for the affected patients. Objective: To evaluate the cost effectiveness of second-line chemotherapy compared with best supportive care for patients with platinum-resistant or refractory epithelial ovarian cancer. Materials and Methods: A Markov model was used to estimate the effectiveness and total costs associated with treatments. The hypothetical patient population comprised women aged 55 with platinum-resistant or refractory epithelial ovarian cancer. Four types of alternative treatment options were evaluated: 1) gemcitabine followed by BSC; 2) pegylated liposomal doxorubicin (PLD) followed by BSC; 3) gemcitabine followed by topotecan; and 4) PLD followed by topotecan. Baseline comparator of alternative treatments was BSC. Time horizon of the analysis was 2 years. Health care provider perspective and 3% discount rate were used to determine the costs of medical treatment in this study. Quality-adjusted life-years (QALY) were used to measure the treatment effectiveness. Treatment effectiveness data were derived from the literature. Costs were calculated from unit cost treatment of epithelial ovarian cancer patients at various stages of disease in King Chulalongkorn Memorial Hospital (KCMH) in the year 2011. Parameter uncertainty was tested in probabilistic sensitivity analysis by using Monte Carlo simulation. One-way sensitivity analysis was used to explore each variable's impact on the uncertainty of the results. Results: Approximated life expectancy of best supportive care was 0.182 years and its total cost was 26,862 Baht. All four alternative treatments increased life expectancy. Life expectancy of gemcitabine followed by BSC, PLD followed by BSC, gemcitabine followed by topotecan and PLD followed by topotecan was 0.510, 0.513, 0.566, and 0.570 years, respectively. The total cost of gemcitabine followed by BSC, PLD followed by BSC, gemcitabine followed by topotecan and PLD followed by topotecan was 113,000, 124,302, 139,788 and 151,135 Baht, respectively. PLD followed by topotecan had the highest expected quality-adjusted life-years but was the most expensive of all the above strategies. The incremental cost-effectiveness ratios (ICER) of gemcitabine followed by BSC, PLD followed by BSC, gemcitabine followed by topotecan and PLD followed by topotecan was 344,643, 385,322, 385,856, and 420,299 Baht, respectively. Conclusions: All of the second-line chemotherapy strategies showed certain benefits due to an increased life-year gained compared with best supportive care. Moreover, gemcitabine as second-line chemotherapy followed by best supportive care in progressive disease case was likely to be more effective strategy with less cost from health care provider perspective. Gemcitabine was the most cost-effective treatment among all four alternative treatments. ICER is only an economic factor. Treatment decisions should be based on the patient benefit.

Development of LCC-LCA Integrated Analysis Model for Efficiency (경제성 평가를 위한 LCC-LCA 종합분석 모델 개발 및 사례적용)

  • Ahn, Hye-Ryeon;Lim, Jin Ho;Huh, Young-Ki
    • Journal of the Korea Institute of Building Construction
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    • v.13 no.6
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    • pp.585-593
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    • 2013
  • For a successful construction project, systematic and objective decision-making is a prerequisite from the planning and designing stages. However, previous LCC analysis methods have focused only on simple cost savings and the accompanying economic efficacy while missing the environmental aspects of a structure. Although recently, a new approach of integrated $CO_2$ analysis has been introduced, which is more advanced than the existing simple LCC methods, it is difficult to collect all of the data necessary for each evaluation item since the product-specific cost is not presented under the LCC. In this research, cost evaluation items were selected by relatively high weights and items with heavy influence over a decision-making process in order to suggest an LCC-LCA integrated analysis model that is useful in comprehensively assessing the economic cost and environmental cost throughout the whole life cycle of a structure. The developed LCC-LCA integrated analysis model was applied to actual practices and compared with previous methods to test the model's effectiveness.

Discussions on the Efficacy, Phytotoxicity and Residue of Organo-Arsenic Fungicides (유기비소제의 약효 및 약해와 잔류에 관한 종합적 고찰)

  • Bai Daihan H.
    • Korean journal of applied entomology
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    • v.18 no.1 s.38
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    • pp.55-61
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    • 1979
  • Since rice high yielding practices with blast resistant varieties induced severe and earlier infestation of sheath blight recently, it is strongly suggested to spray at least 10 days earlier than the present recommendation and more than 2 sprays from early July to early August seems to be essential for the efficient control of sheath blight in the future. Among organo-arsenic fungicides, MAFe (Neo Asozin) is known as the most effective and economic as well as with the advantages of free phytotoxicity and safe residure on rice, and applications of the mixed formulation with other fungicide and insecticide is suitable for the one-hit control of rice diseases and insect pests in connection with cooperative mass control system. Present level of arsenic $(As_2O_3)$ residue in .ice is summarized as 0.2ppm to 0.65 ppm in highest average, and there are more possibilities of extensive MAFe fungicide uses for the efficient and economic control of this disease. During the past few years, the acreage of sheath blight control has been extended several times while the increase of the fungicides used for sheath blight showing about 10 times in quantity and mort than 15 times in amount, and also the fungicide cost estimated for the control is differ from 1 to 12 billion 1on by the use of MAFe or antibiotic fungicide in a year.

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Effects of Iranian Economic Reforms on Equity in Social and Healthcare Financing: A Segmented Regression Analysis

  • Zandian, Hamed;Takian, Amirhossein;Rashidian, Arash;Bayati, Mohsen;Moghadam, Telma Zahirian;Rezaei, Satar;Olyaeemanesh, Alireza
    • Journal of Preventive Medicine and Public Health
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    • v.51 no.2
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    • pp.83-91
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    • 2018
  • Objectives: One of the main objectives of the Targeted Subsidies Law (TSL) in Iran was to improve equity in healthcare financing. This study aimed at measuring the effects of the TSL, which was implemented in Iran in 2010, on equity in healthcare financing. Methods: Segmented regression analysis was applied to assess the effects of TSL implementation on the Gini and Kakwani indices of outcome variables in Iranian households. Data for the years 1977-2014 were retrieved from formal databases. Changes in the levels and trends of the outcome variables before and after TSL implementation were assessed using Stata version 13. Results: In the 33 years before the implementation of the TSL, the Gini index decreased from 0.401 to 0.381. The Gini index and its intercept significantly decreased to 0.362 (p<0.001) 5 years after the implementation of the TSL. There was no statistically significant change in the gross domestic product or inflation rate after TSL implementation. The Kakwani index significantly increased from -0.020 to 0.007 (p<0.001) before the implementation of the TSL, while we observed no statistically significant change (p=0.81) in the Kakwani index after TSL implementation. Conclusions: The TSL reform, which was introduced as part of an economic development plan in Iran in 2010, led to a significant reduction in households' income inequality. However, the TSL did not significantly affect equity in healthcare financing. Hence, while measuring the long-term impact of TSL is paramount, healthcare decision-makers need to consider the efficacy of the TSL in order to develop plans for achieving the desired equity in healthcare financing.

Interaction of Breed-by-chitosan Supplementation on Growth and Feed Efficiency at Different Supplementing Ages in Broiler Chickens

  • Suk, Y.O.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.12
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    • pp.1705-1711
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    • 2004
  • Three experiments were conducted to investigate the interaction of breed-by-chitosan supplementation on the major economic traits in broiler chickens. In experiment 1, one-day-old broiler chicks were fed ad libitum on a basal diet (CON-group) or basal diet containing chitosan at an inclusion level of 10.5 mg/bird/day (EXP-group). The EXP-group birds in experiments 2 and 3 were supplemented from 15 day-old by the same amount of chitosan used in experiment 1. In experiment 1, the mean body weight of the EXP-group chickens was significantly (p<0.05) heavier in comparison with those of CON-group birds from day 21 of the experiment. Especially in 35 day-old mean body weight, the EXP-group birds of Arbor Acres, Peterson, and Ross were significantly (p<0.05) heavier by 121.8 g, 118.5 g, and 242.8 g than the CON-group birds, respectively. However, the mean body weights in experiments 2 and 3 did not significantly differ between the CON-group birds and the EXP-group birds fed with chitosan supplementation from day 15 post birth. In the comparisons among breeds on the mean body weight at 35 day-old, the birds of Arbor Acres were significantly (p<0.05) heavier than ones of Peterson or Ross; however, there were no significant differences between Peterson and Ross or Cobb and Ross birds in overall in the experiments. The mean 15-35 d FCR of the EXP-group birds in experiment 1 were significantly (p<0.05) lower at least in two of the three breeds (Arbor Acres and Ross breeds) than that of the CON-group birds. None of the mean 15-35 d FCR in either experiment 2 or 3 showed significant differences between groups within a breed. In all three experiments, the differences amongst breeds in the mean 15-35 d FCR were not great either. Significant differences were not generally shown in the mean percentage of abdominal fat deposition between groups within a breed in overall experiments except in the Cobb breed in experiment 3. The mean percentages of abdominal fat deposition were significantly (p<0.05) lower in Ross birds than in Arbor Acres or Peterson birds and in Cobb birds than in Ross birds. By the results of the analysis of variance, the interaction of breed-by-diet (chitosan) supplementation on any of the major economic traits including mean percentage of abdominal fat deposition was not significant in overall experiments. Results of these experiments indicate that dietary supplementation with chitosan for the improvement of growth or feed conversion ratio in broilers has an efficacy when the supplementation begins from day-old.