• Title/Summary/Keyword: Ec

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Effect of Water Extract of Eucommiae cortex In RANKL-induced Osteoclast Differentiation (두충의 물 추출물이 파골세포의 분화에 미치는 영향)

  • Jung, Yeon-Tae;Choi, Yun-Hong;Song, Jeong-Hoon;Lee, Chang-Hoon;Lee, Myeung-Su;Jang, Sung-Jo;Cho, Hae-Joong;Kwak, Han-Bok;Oh, Jae-Min
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.3
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    • pp.613-618
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    • 2009
  • Although the effect of Eucommie umoides oliver in osteoporosis has been studied, direct action of Eucommis ulmoides Oliver on osteoclasts remains unknown. Here we examined whether Eucommiae cortex inhibits osteoclast differentiation and bone resorption, a process known to be involved in bone diseases such as osteoporosis. Water extract from Eucommiae cortex (WE-EC) inhibited differentiation of bone marrow macrophages (BMMs) into osteoclasts without causing cytotoxicity. WE-EC suppressed the phosphorylation of p38, ERK, and JNK in BMMs treated with RANKL. WE EC specifically suppressed the mRNA expression of NFATc1 induced by RANKL. However, WE-EC inhibited stability of c-Fos protein induced by RANKL. Furthermore, WE-EC inhibited osteoclast survival induced by RANKL and in turn suppressed bone resorption. Taken together, our results suggest that WE-EC may be better agents for therapeutic use in bone diseases.

A method of Securing Mass Storage for SQL Server by Sharing Network Disks - on the Amazon EC2 Windows Environments - (네트워크 디스크를 공유하여 SQL 서버의 대용량 스토리지 확보 방법 - Amazon EC2 Windows 환경에서 -)

  • Kang, Sungwook;Choi, Jungsun;Choi, Jaeyoung
    • Journal of Internet Computing and Services
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    • v.17 no.2
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    • pp.1-9
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    • 2016
  • Users are provided infrastructure such as CPU, memory, network, and storage as IaaS (Infrastructure as a Service) service on cloud computing environments. However storage instances cannot support the maximum storage capacity that SQL servers can use, because the capacity of instances provided by service providers is usually limited. In this paper, we propose a method of securing mass storage capacity for SQL servers by sharing network disks with limited storage capacity. We confirmed through experiments that it is possible to secure mass storage capacity, which exceeds the maximum storage capacity provided by an instance with Amazon EBS on Amazon EC2 Windows environments, and it is possible to improve the overall performance of the SQL servers by increasing the disk capacity and performance.

Weed Occurrence and Control in Simultaneous Wheat Sowing Culture with Rice Harvest under No-tilled Paddy Field (무경운(無耕耘) 벼 수확동시(收穫同時) 밀 파종에서 잡초(雜草)발생과 방제)

  • Kim, Dae-Ho;Kim, Su-Kyeong;Kim, Eun-Seok;Son, Beom-Young;Kang, Dong-Ju
    • Korean Journal of Weed Science
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    • v.18 no.3
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    • pp.186-190
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    • 1998
  • To establish weed control method in no-tilled and rice straw-covered wheat sown coincidentally with rice harvest using combine-attached drill seeder, several herbicides and their combination were tested for 2 years. Similar number of panicle to hand-weeding plot was secured at sprayed plot with Buta EC + Glyphosate SL mixture just after seeding. Water-foxtail(Alopeculus aequalis) and broadleaf weeds were controlled effectively by Buta EC + Glyphosate SL mixture, showing the control efficacy of 92 percent. In the 1st cropping year, weed species occurred was simple and water-foxtail predominated nearly half. However, weed species was diversified and water-foxtail predominated 83.5 percent in the 2nd cropping year. Wheat yield of Buta EC + Glyphosate SL plot showed no difference with hand-weeding plot. Dry weight of water-foxtail showed closer linear relationship with wheat yield reduction than that of broadleaf weed.

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Therapeutic Potential of Ethanolic Extract of Ecklonia cava on Inhibition of Inflammation

  • Kim, Moon-Moo;Lee, Sang-Hoon;Ngo, Dai-Nghiep;Jung, Won-Kyo;Kim, Se-Kwon
    • Journal of Marine Bioscience and Biotechnology
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    • v.2 no.2
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    • pp.86-93
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    • 2007
  • Chronic inflammation has been known to have a close relationship with several diseases including periodontitis, colitis, hepatitis and arthritis. Recently anti-inflammatory agents have been developed from marine natural resources. In this study, Ecklonia cava (EC) was found to have anti-inflammatory effect. Ethanolic extract of EC belonging to brown algae exhibited an excellent inhibitory effect on the production of inflammatory mediators such as tumor necrosis factor-${\alpha}$, interleukin-$1{\beta}$, interleukin-6 and prostaglandin $E_2$ by RA W264.7 cells. Furthermore, in reporter gene assay and western blot analysis, EC extract exerted anti-inflammatory effect via inactivation of NF-${\kappa}B$ transcription factor that regulates the expression of these inflammatory mediators in macrophages. In addition, EC extract inhibited the activity of matrix metalloproteinase that play an important role in chronic inflammation. These results suggest that EC extract may provide a pharmaceutical potential in inhibiting chronic inflammation.

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Fabrication of SnO2-based All-solid-state Transmittance Variation Devices (SnO2 기반 고체상의 투과도 가변 소자 제조)

  • Shin, Dongkyun;Seo, Yuseok;Lee, Jinyoung;Park, Jongwoon
    • Journal of the Semiconductor & Display Technology
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    • v.19 no.3
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    • pp.23-29
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    • 2020
  • Electrochromic (EC) device is an element whose transmittance is changed by electrical energy. Coloring and decoloring states can be easily controlled and thus used in buildings and automobiles for energy saving. There exist several types of EC devices; EC using electrolytes, polymer dispersed liquid crystal (PDLC), and suspended particle device (SPD) using polarized molecules. However, these devices involve solutions such as electrolytes and liquid crystals, limiting their applications in high temperature environments. In this study, we have studied all-solid-state EC device based on Tin(IV) oxide (SnO2). A coloring phase is achieved when electrons are accumulated in the ultraviolet (UV)-treated SnO2 layer, whereas a decoloring mode is obtained when electrons are empty there. The UV treatment of SnO2 layer brings in a number of localized states in the bandgap, which traps electrons near the conduction band. The SnO2-based EC device shows a transmittance of 70.7% in the decoloring mode and 41% in the coloring mode at a voltage of 2.5 V. We have achieved a transmittance change as large as 29.7% at the wavelength of 550 nm. It also exhibits fast and stable driving characteristics, which have been demonstrated by the cyclic experiments of coloration and decoloration. It has also showed the memory effects induced by the insulating layer of titanium dioxide (TiO2) and silicone (Si).

A Study on Adsorption Characteristics of Natural Organic Matter and Taste & Odor Using Activated Carbon (활성탄 흡착지에서 응집조건에 따른 자연유기물질과 이·취미(Geosmin, 2-MIB) 파과특성에 관한 연구)

  • Kim, Sung-Jin;Hong, Seong-Ho;Shin, Heung-Sup
    • Journal of Korean Society of Water and Wastewater
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    • v.21 no.1
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    • pp.91-99
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    • 2007
  • It is well-known that the presence of NOM (natural organic matter) in water has a negative effect on removing taste and odor compounds by activated carbon adsorption. Therefore, various means such as enhanced coagulation are applied to reduce the NOM. The presence of taste & odor compounds in drinking water even parts per trillion, is enough to generate customer dissatisfaction. Therefore, the aim of this study was to evaluate carbon usage rate (CUR) for conventional coagulation (CC) and enhanced coagulation (EC) in order to improve the efficiency of adsorption of taste and odor compounds. Also, Effect of CC and EC on molecular weight fraction and the early stage breakthrough of 2-MIB and Geosmin are evaluated. When the enhanced coagulation was adapted for pretreatment for activated carbon adsorption the operation period could be prolonged by 3.5~4 times. CUR for CC was about 2 times greater than CUR for EC and this means that EC has more adsorption capacity than CC. To analyze effect of EC and CC on breakthrough of 2-MIB quantitatively, adsorbed NOM mass was calculated based on unit mass of activated carbon. In the early stage breakthrough of 2-MIB, total adsorbed NOM was 23.72mg/g for CC and 34.56mg/g for EC. Therefore, it is shown that the early breakthrough term of 2-MIB and Geosmin was improved due to increased adsorbability. The low-molecular-weight NOM (500~2000Da) compounds were the most competitive, participating in direct competition with 2-MIB for adsorption site.

Effects of Nutrient Solution on Growth and Amount of Ginsenoside of Two Year Old Ginseng Grown under Hydroponic Culture (수경재배 양액조건이 2년생 인삼의 생육 및 진세노사이드 함량에 미치는 영향)

  • Yu, Jin;Jang, In Bae;Suh, Soo Jung;Kweon, Ki Bum
    • Korean Journal of Medicinal Crop Science
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    • v.24 no.3
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    • pp.198-206
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    • 2016
  • Background: Electrical conductivity (EC) and pH are important features of nutrient solution, affecting both growth and quality of crops by altering nutrient uptake. Methods and Results: The pH values of nutrient solutions were controlled at 5.0, 5.5, 6.0, 6.5 and EC values were controlled at 0.68, 0.84, 1.23, 1.41 dS/m. Gingesng root weights were higher during the initial growth period when the plants were treated with low pH and low EC nutrient solutions. However, the higher pH and EC levels, the greater the increase in the rate of root weight between the initial and middle growth periods. The highest ginsenoside amount changed during growth period. The total ginsenoside amount was highest in the root, and the lowest in leaves at 45 and 90 days after treatment, respectively, with solution at a pH of 6.0. After 135 days of treatment, the highest total ginsenoside amount was detected in root treated with soluton with EC values of 1.23 dS/m. Conclusions: For the cultivation of ginseng using a nutriculture system, the pH and EC values of nutrient solutions should to be controlled based on the stage of growth and targeted plant organ (root or leaves).

Effect of Condensed Tannins Prepared from Banana (Musa Sapientum L.) fruit on Digestive Enzyme In vitro (바나나 과실 함유탄닌이 소화효소 작용에 미치는 영향)

  • Chung, Chung-Han;Ryu, Chung-Ho;Cho, Young-Su
    • Applied Biological Chemistry
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    • v.39 no.6
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    • pp.477-481
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    • 1996
  • It has been shown that tannins have adverse effects on growth of animals and feed utilization. Tannins are usually classified into hydrolyzable and condensed types but the adverse effects are more marked in condensed tannin in hydrolyzable tannin. Furthermore, the principle condensed tannins found in banana fruits are pro types by the polymerization of flavan-3, 4-diols either alone or in combination with other flavonoids such as catechins. Tannin of the investigated banana(Banana; Musa sapientum LINN)fruits was fractionated into four or five molecular forms, according to the degree of polymerization by chromatography on a column of Sephadex LH-20. The protein-precitating capacity of the fraction noted tannins increased in degree polymerzation. The inhibitory effect of tannins on trypsin(EC 3. 4. 21. 4), ${\alpha}-amylase$(EC 3. 2. 1. 1) and lipase(EC 3. 1. 1. 3) activities in vitro also increased with the incraesed in degree of polymerization.

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Toxicity Assessment of Ocean Dumping Wastes Using Fertilization and Embryo Development Rates in the Sea Urchin (Strongylocentrotus nudus) (둥근성게(Strongylocentrotus nudus)의 수정 및 배 발생률을 이용한 해양배출 폐기물의 독성평가)

  • Hwang, Un-Ki;Rhee, Choong-Won;Kim, Kwang-Seop;Kim, Hyoung-Choul;An, Kyoung-Ho;Park, Seung-Youn
    • Environmental Analysis Health and Toxicology
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    • v.24 no.1
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    • pp.25-32
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    • 2009
  • Toxicity of ocean dumping wastes(dye waste, urban sewage, food waste) were examined by observing fertilization and embryo development rates of the Sea Urchin, Strongylocentrotus nudus. Spawning was induced by injecting 1 mL of 0.5 M KCl into coelomic cavity. Males released white or cream-colored sperms and females released yellow or orange-colored eggs. Experiments were began within 30 min after the collection of both gametes. The fertilization and embryo development rates tests were performed for 10 min and 48 h after fertilization, respectively. The fertilization and embryo development rates in the control condition(not including ocean dumping wastes sludge elutriate) were greater than 90%, but markedly decreased with increasing concentrations of ocean dumping waste sludge elutriate. The fertilization and normal embryogenesis rates were significantly inhibited in all waste sludge elutriate from dye waste($EC_{50}$=5.76; $EC_{50}$=4.53), urban sewage($EC_{50}$=9.82; $EC_{50}$=9.67) and food waste($EC_{50}$=3.90; $EC_{50}$=3.27), respectively. The NOEC(>3.13%) and LOEC(3.13%) of fertiliztion and normal embryogenesis rates very similar in all waste sludge elutriate. These results suggest biological assay using the fertilization and embryo development rates of S. nudus are very useful test method for the ecological toxicity assessment of ocean dumping wastes.

Seasonal Change Characteristics of Stream Water Quality in Planted Coniferous Forest (침엽수 인공림 계류수 수질의 계절변화 특성)

  • Kim, Jaehoon;Choi, Hyung Tae;Yoo, Jae Yun
    • Korean Journal of Environment and Ecology
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    • v.29 no.6
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    • pp.929-935
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    • 2015
  • This study was carried out to investigate pH, EC, solutes concentration and ANC characteristics in coniferous forest experiment watershed in Gyeonggi-do, Korea from 2005 to 2007. The average pH value was 6.87 and low at spring season due to deposition in crown. The average EC was $58.4{\mu}S/cm$ and was high at spring season due to high concentration of solutes. The cation and anion concentration was high at spring and fall season with low rainfall. When stream water quality was compared to different watershed, EC was relatively low due to high rainfall and $NO_3{^-}$ was high due to deposition and forest practice. pH and ANC was relatively constant at stream water