• Title/Summary/Keyword: Ec

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Effects of Phenobarbital Pretreatment on Ethyl Carbamate-induced Embryotoxicity in Rats

  • Chung, Moon-Koo;Jiang, Cheng-Zhe;Kim, Jong-Choon;Yun, Hyo-In;Han, Sang-Seop;Roh, Jung-Koo
    • Toxicological Research
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    • v.13 no.1_2
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    • pp.95-101
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    • 1997
  • Ethyl carbamate (EC) is a potent teratogen in rodents and is present at low concentration in fermented foods and alcohol beverages. It has been well hypothesized that some metabolic products are responsible for the teratogenic effects of the compound. In the present study, the effects of phenobarbital (PB) on EC-induced embryotoxicity were investigated in SD rats. Six groups were constructed: EC 300 (EC 300 mg/kg/day), EC 600 (EC 600 mg/kg/day), EC 600+PB (EC 600 mg/kg/day and PB 80 mg/kg/day), PB (PB 80 mg/kg/day), DR (dietary restriction, 8 g/day/rat) and a control group. Rats of the EC 600+PB group were pretreated with phenobarbital intraperitoneally for three days to induce cytochrome P450 enzymes, followed by oral administration of EC for two consecutive days. The incidence of fetal deaths in the EC 600+PB group was higher than that of the EC 600 group(42.7 vs. 14.3%). The incidence of fetal realformations in the EC 600+PB group was higher than that of the EC 600 group (external; 7.0 vs. 4.1%, visceral; 31.4 vs. 11.3%, skeletal; 11.1 vs. 6.5%). There was no embryotoxicity in the control, EC 300, PB and DR groups. These results show that the pretreatment with phenobarbital augments EC-induced embryotoxicity in rats, indicating an evidence that metabolic activation by cytochrome P450 may be the major pathway of EC to its embryotoxic forms.

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Estimating Saturation-paste Electrical Conductivities of Rose-cultivated Soils from their Diluted Soil Extracts (절화장미 재배토양에서 희석된 토양 침출용액으로부터 포화반죽 전기전도도 추정)

  • Lee, In-Bog;Ro, Hee-Myong;Lim, Jae-Hyun;Yiem, Myoung-Soon
    • Korean Journal of Soil Science and Fertilizer
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    • v.33 no.6
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    • pp.398-404
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    • 2000
  • We examined the effect of soil:water ratio on the equivalent concentration of individual electrolyte species and the electrical conductivities (EC) of the diluted extracts of 24 soil samples (loam or silt loam) collected from rose-cultivated plastic houses to estimate the EC of saturated soil-paste extracts (ECe) from diluted soil extracts. With increasing volume ratio of water (higher dilution), the equivalent concentrations of each electrolyte species and their sum increased. The relative contribution to the EC, however, was highest for $NO_3{^-}$, irrespective of soil:water ratio. The measured ECe was 6.36 for loam and $8.09dS\;m^{-1}$ for silt loam soils and the corresponding soil:water ratio was 0.38 and 0.50, respectively. The EC_e estimated from the EC of diluted extracts at 1:1, 1:2, or 1:5 soil:water ratios using their corresponding uniform diluted factors was lower than the measured EC_e and this difference was greater with higher dilution and EC values. Therefore, the alternative diluted factors (y) for each soil: water ratio were obtained following the definition of diluted factor and were correlated significantly with volume ratios of added water (x): y=1.55x+0.5 for loam and y=1.21x+0.48 for silt loam soils. On the other hand, correlation analyses of the EC of soil extracts (y) to the volume ratio of added water (x) on log-log scale yielded linear models: logy = -0.805logx + logb, SD of slope=0.05, b=sample specific constant, n=24). With known saturation percentage of a sample representing a group and and the EC of diluted extract of a given soil, the EC_e could be predicted using the proposed logarithmic equation.

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A Study on the Embedded Capacitor for High Frequency Decoupling (고주파용 디커플링 임베디드 캐패시터에 관한 연구)

  • Hong, Keun-Kee;Hong, Soon-Kwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.4
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    • pp.918-923
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    • 2008
  • We proposed an embedded capacitor with the unique electrode structure, which electrodes are located on the same plane and dielectric gap was formed by electrodes. We named it 'Gap type EC', and it was analyzed by the FEM(Finite element Method) program tool. The resonant frequency of Cap type EC was obtained at more higher frequency region. Also, resonant frequency was changed with the magnitude and thickness of electrodes. The Gap type EC with the dielectric gap of $50{\mu}m$ showed capacitance density of $55pF/cm^2$. This value is the higher than that of conventional EC. So, we concluded that the Gap type EC can be a good candidate for high frequency decoupling.

Effects of Initial EC Values on Seedling Growth and Utilization of Minerals in Hydroponic Rice Seedling Raising (벼 수경육묘에서 양액의 EC 초기 설정에 따른 묘 생육과 무기성분의 이용)

  • 김영광;홍광표;정완규;손길만;송근우;강진호
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.48 no.3
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    • pp.200-204
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    • 2003
  • This study was conducted to develop a technology for raising seedlings hydroponically using the bed in which the seedlings grew in nutrient solution without soil. In order to establish the optimum EC value of nutrient solution, six initial EC values (1, 2, 3, 4, 5 dS/m and control) of Yoshida's hydroponic solution were examined. Seedling height and dry weight increased with increasing below EC up to 3.0 dS/m, but showed no significant increase at higher than EC 3.0 dS/m. Nutrient solution with initial EC of 3.0 dS/m was good to be dropped down nearly to 1 dS/m after 15-day seedling culture. But those with initial EC of 4.0 and 5.0 dS/m were judged not appropriate because of high EC value in waste nutrient solution. Utilization efficiency of minerals of nutrient solution and rice endosperm was higher on the whole at initial EC of 2.0-3.0 dS/m. Considering seedling growth and utilization efficiency of supplied nutrient solution, initial EC is judged to be suitable at 3.0 dS/m.

A Study on EC Strategic Classification Scheme (EC 전략유형분류체계에 관한 연구)

  • 조선구;이국철
    • Proceedings of the Korea Database Society Conference
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    • 1999.10a
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    • pp.69-91
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    • 1999
  • EC의 도입이 국가 및 기업의 국제경쟁력향상을 확보하기 위한 필연적인 해결책이라는 인식하에서, EC의 경쟁력 향상을 위한 유형별 전략모형을 제시함으로서 EC 도입전략의 가이드라인 제공을 목적으로 한다. 구체적으로는 1) Developing strategically classified models and Modeling the structured service of EC to verify the models. (중략)

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Perceived Importance of B2B Electronic Commerce Success Factors: An Empirical Evidence of Enterprise′s IS and EC Characteristics (기업의 IS/EC 특성에 따른 B2B 전자상거래 성공요인의 중요도 분석에 관한 실증적 연구)

  • 정대율
    • The Journal of Information Systems
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    • v.11 no.2
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    • pp.47-72
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    • 2002
  • In the beginning of new millennium, Business-to-Business(B2B) Electronic Commerce(EC) is a hot issues of the world business and economic communities. The market of B2B EC is increasing rapidly, and become a more complex and competitive because many participants and intermediaries are play on their own objectives and strategies. To cope with the situation, participants of B2B EC market should make play with a competitive strategies. So, the participant enterprises must know the critical success factors of their own EC market. This study identifies B2B EC success factor measurement sets, and explores several success factors based on the perceived importance of B2B EC practitioner in the manufacturing enterprises. The study tests the differences of success factors by IS level, EC business model characteristics, and EC introduction and operating characteristics.

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The Effect of EC Utilization on Business Performance in SMEs(in the point of BSC) (중소기업의 전자상거래 활용수준과 경영성과간의 관계(BSC 관점에서))

  • Jun Byoung-Ho;Han Pil-Koo;Kang Byung-Goo
    • Journal of Information Technology Applications and Management
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    • v.13 no.2
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    • pp.99-113
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    • 2006
  • It is hardly achieved Electronic Commerce (EC) activation if there isn't any performance in spite of the estimation that EC would improve whole economic efficiency. Therefore, there should be a need for the research whether implementation and utilization of EC really improve companies' business performance. The primary purpose of this study is to investigate the level of EC utilization in Small and medium sized enterprises (SMEs) and analyze its effect on business performance in terms of BSC. The results indicate that EC utilization in various fields of business and the use of information created through EC are significantly related to higher business performance, but EC volume is not. This study examines facing problems of SMEs in utilizing EC as well.

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Determination of Optimum EC of Nutrient Solution by Season in Closed System of Rosa hybrida by Total Integrated Solar Radiation (장미 일사비례제어에 의한 순환식 양액재배시 계절별 급액 EC농도 구명)

  • Na, Taek-Sang;Choi, Kyong-Ju;Cho, Myoung-Soo;Gi, Gwang-Yeon;Yoo, Yong-Kweon
    • Journal of Bio-Environment Control
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    • v.14 no.4
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    • pp.245-253
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    • 2005
  • This study was carried out to determine the optimum EC supply by accumulation amount of solar radiation in closed system. EC concentration of drainage was higher than that of supply. The higher EC concentration of supply was, the lower pH of drainage was. It was no difference in the quality of cut rose 'Nobles' (Rosa hybrida), stem length, stem diameter, leaf number, petal length, and petal diameter by EC treatment by season. The yield was higher about $6\%$ in treatment of EC $1.3dS{\cdot}m^{-1}$ in April and May, about $10\%$ in treatment of EC $10dS{\cdot}m^{-1}$ in June, July and August, and about $10\%$ in treatment of EC 1.0 or $1.3dS{\cdot}m^{-1}$ in September and October than the others. In general, the yield of the cut rose was higher in treatment of (B) EC 1.3 mS/cm in spring, EC $1.0dS{\cdot}m^{-1}$ in summer, EC $1.3dS{\cdot}m^{-1}$ in autumn, and EC$1.6dS{\cdot}m^{-1}$ in winter.

Precise Control of Nutrient Solution and Analysis of Ionic Contribution to EC Reading (양액의 정밀 제어 및 이온의 EC 기여도 분석)

  • Son, Jung-Eek
    • Horticultural Science & Technology
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    • v.16 no.3
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    • pp.352-354
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    • 1998
  • A soilless culture system with the precise control of nutrient solution was developed and the time changes of ionic contribution to EC reading was analyzed. The measuring device designed was able to wash electrodes cleanly and to measure the pH and EC of nutrient solution stably in the box. The nutrient supply system using metering device was also able to control the EC and pH within ${\pm}0.05mS/cm$ and ${\pm}0.05$, respectively. Under the EC control, activity coefficients of all ions decreased with time as ionic concentrations of $SO_4$, Mg and Ca increased due to the selective nutrient absorption by plants. Time changes of ionic contribution to EC reading could be calculated using equivalent ionic conductivities and activity coefficients obtained by numerical analysis.

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Extracellular Superoxide Dismutase (EC-SOD) Transgenic Mice: Possible Animal Model for Various Skin Changes

  • Kim, Sung-Hyun;Kim, Myoung-Ok;Lee, Sang-Gyu;Ryoo, Zae-Young
    • Reproductive and Developmental Biology
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    • v.30 no.4
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    • pp.229-234
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    • 2006
  • We have generated transgenic mice that expressed mouse extracellular superoxide dismutase (EC-SOD) in their skin. In particular, the expression plasmid DNA containing human keratin K14 promoter was used to direct the keratinocyte-specific transcription of the transgene. To compare intron-dependent and intron-independent gene expression, we constructed two vectors. The vector B, which contains the rabbit -globin intron 2, was not effective for mouse EC-SOD overexpression. The EC-SOD transcript was detected in the skin, as determined by Northern blot analysis. Furthermore, EC-SOD protein was detected in the skin tissue, as demonstrated by Western blot analysis. To evaluate the expression levels of EC-SOD in various tissues, we purified EC-SOD from the skin, lungs, brain, kidneys, livers, and spleen of transgenic mice and measured its activities. EC-SOD activities in the transgenic mice skin were approximately 7 fold higher than in wild-type mice. These results suggest that the mouse overexpressing vector not only induces keratinocyte-specific expression of EC-SOD, but also expresses successfully functional EC-SOD. Thus, these transgenic mice appeared to be useful for the expression of the EC-SOD gene and subsequent analysis of various skin changes, such as erythema, inflamation, photoaging, and skin tumors.