• The Journal of Korean Physical Therapy
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• 제22권5호
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• pp.63-70
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• 2010

Purpose: In this study, children with cerebral palsy were treated for 8 weeks using horse riding trunk proprioception, stability and posture to investigate the effect of hippotherapy in the field of physical therapy. Methods: A total of 18 subjects were divided into an experimental group treated by horseback riding and a control group. Both groups were evaluated pre- and post-treatment. Trunk proprioception was measured three times in the sitting position with their eyes and ears closed to reach the target position the angle error of the mean was calculated. Trunk stability was measured using a forceplate and the data were used to calculate the postural sway path & postural sway velocity. Posture was evaluated using the Posture Assessment Scale (PAS). Results: After hippotherapy, the experimental group showed a significant improvement in trunk proprioception, stability and posture (p<0.05), but the control group improved in posture only (p<0.05). Trunk proprioception, stability and posture was significantly different between the two groups (p<0.05). Conclusion: Eight weeks of hippotherapy is effective in improving trunk proprioception, stability, and posture. Research using this therapy should be studied further as a possible new therapeutic approach in the field of physical therapy.

• Biomolecules & Therapeutics
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• 제5권1호
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• pp.12-22
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• 1997

Intravenous and oral acute toxicity tests in ICR mice and SD rats and percutaneous acute toxicity tests in SD rats and NZW rabbits were conducted to evaluate the toxicity of DA-5018 and DA-5018 cream, respectively Clinical signs observed in mice and rats after the administration of DA-5018 were similar regardless of administration route. The observed clinical signs were jumping, wild running, lacrimation, ataxia, reddening of extremities and ears, ventral or lateral recumbency, respiratory distress, cyanosis, convulsion and death. Pulmonary enlargement and hemorrhage were observed in the animals died immediately after the dosing of DA-5018. At terminal necropsy, pulmonary enlargement and hemorrhage, corneal opacity and focal scabbing and depilation around nose were seen. LD$_{50}$ Values of DA-5018 are 11.5 mg/kg (mice, male), 12.6 mg/kg (mice, female), 88.3 mg/kg (rat, male) and 73.2 mg/kg (rat, female) in oral toxicity tests and 11.0 mg/kg (mice, male), 18.7 mg/kg (mice, female), 0.12 mg/kg (rat, male) and 0.32 mg/kg (rat, female) in i.v. toxicity tests. In the percutaneous acute toxicity tests of DA-5018 cream, no deaths occured in all the tested groups during 14-day observation period. There were also no abnormalities in the general conditions, body weight changes and on necropsy findings in all groups. LD$_{50}$ values of 0.1 ~0.9% DA-5018 creams in male and female rats and rabbits are >2000 mg/kg./kg.

• 대한장애인치과학회지
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• 제4권1호
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• pp.12-16
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• 2008

Williams syndrome is a rare genetic disorder with a frequency of one per 20,000~50,000 live births. It is caused by a deletion of one elastin allele located within chromosome subunit 7q11.23(long arm). This syndrome is frequently accompanied by disorders such as congenital heart disease, facial anomalies, mental retardation, and so on. The characteristic facial appearance includes full lips, rounded cheeks, broad forehead, periorbital fullness, flattened bridge of nose, small nose with anteverted nostril, long filtrum and low-set ears. In oral features, hypodontia, high prevalence of dental caries, microdontia, enamel hypoplasia, delayed eruption, and malocclusions have been found. Most adult patients with Williams syndrome lack social adaptability and lead seclusive lives, however, young patients are rather very friendly and talkative, and seem smarter than their actual intellectual quotients. They also tend to favor staying with grown-ups rather than mixing with their peers, and tend to present problematic temper tantrum during dental treatment.

• Clinical and Experimental Pediatrics
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• 제49권12호
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• pp.1354-1357
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• 2006

영아 급성 출혈성 부종은 2세 이전에 발생하는 드문 혈관염의 일종이다. 영아 급성 출혈성 부종은 현저한 말단부 부종과 발열을 보이며 특징적으로 얼굴, 귀, 사지에 두드러지게 헤노호-쉔라인 자반증과 유사한 피부 병변이 발생한다. 이러한 피부 병변은 1주일에서 3주일 사이에 저절로 소실되며 헤노호-쉔라인 자반증과 달리 내부 장기의 침범은 거의 없다. 처음 헤노호-쉔라인 자반증으로 생각하였으나 특징적인 발진의 분포와 전신 증상의 부재 등의 차이로 영아 급성 출혈성 부종으로 진단하게 된 23개월 남아의 증례를 보고하는 바이다.

• Neonatal Medicine
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• 제16권1호
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• pp.89-93
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• 2009

저자들은 당뇨병이 임신 초기부터 진단된 산모에서 출생한 신생아에서 작은 악안면, 우측소이증, 오른손의 손가락다지증, 오른쪽 눈물샘의 위치 이상이 동반된 상검판 기형, 근위부 공장폐쇄증을 지닌 사례와 수술 후 공장 부위의 협착증을 중재적 방사선 시술로 치료하였기에 문헌 고찰과 함께 보고하는 바이다.

• 한국작물학회지
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• 제37권5호
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• pp.413-418
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• 1992

질소시비수준과 추비방법이 율무의 생육과 종실수량에 미치는 영향을 구명하고자 애원종을 공시하여 시험한 결과를 요약하면 다음과 같다. 1. 시비량과, 추비 횟수가 증가할수록 초장, 엽수, 주당경수, 정립비율, 1$\ell$중, 100립중, 10a당 종실중의 수량형질은 질소 14kg / 10a의 적은 량을 기비로 40%, 1차 추비로 30%, 2차 추비로 20%, 그리고 3차로 10%를 시용했거나 180kg / 10a의 많은 량을 전량기비로 시용했을 때 모두 높게 나타났다. 3. 분산분석에서도 시비량간, 시비방법간, 시비량과 시비방법간의 교호작용에서도 유의차를 나타내었다.

• Journal of Ginseng Research
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• 제29권2호
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• pp.80-85
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• 2005

Antiallergic and antipsoriatic effects of korean Red Ginseng (KRG, steamed root of panax ginseng C.A. Meyer, Family Araliaceae) were measured. Orally administered KRG water extract potently inhibited passive cutaneous anaphylaxis (PCA). KRG water extract also showed the potent inhibition in oxazolone-induced mouse dermatitis, and suppressed mouse ear swelling by $39\%$ at 16 days at a dose of $0.1\%$. KRG water extract reduced the levels of mRNA of cyclooxygenase (COX)-2, $IL-1\beta$, $TNF-\alpha$ and $INF-\gamma$ increased in oxazolone-applied mouse ears, however, did not inhibit that of IL-4. KRG water extract also inhibited iNOS and COX-2 mRNA expression level of RAW264.7 cell induced by lipopolysaccharide. Based on these findings, we suggest that KRG can improve atopic and contact dermatitis by the regulation of $ IL-1\beta$ and $TNF-\alpha$ produced by macrophage cells and $interferon-\gamma$ produced by Th1 cells.

• 방송공학회논문지
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• 제11권4호
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• pp.448-457
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• 2006

일반적으로 3D 입체음향을 생성하기 위해서는 소리가 음원으로부터 청자의 두 귀에 이르는 정보를 포함하고 있는 머리전달함수를 사용한다. 그러나 HRTF의 비개인화적인 특성 때문에 양쪽 귀까지의 거리가 같아지는 혼돈원추상에서는 앞/뒤 방향지각에 대한 혼돈을 주게 됨으로써 입체감을 저하시키게 된다. 이에 본 논문에서는 인간의 청각특성에 따른 여기에너지를 이용하여 앞/뒤 음상정위의 특성을 개선하는 방법을 제안하고자 한다. 서로 대칭되는 각 HRTF의 여기 에너지를 계산하고 각 bark 대역에 따른 에너지의 비율을 추출하는 방식으로써 각 HRTF의 스펙트럼 특성을 부각시키는 방법을 제안하였으며 청감테스트를 통해서 제안한 방식이 기존 방법보다 방향감을 개선시킴을 확인할 수 있었다.

• Journal of Oral Medicine and Pain
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• 제20권2호
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• pp.257-267
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• 1995

An Epidemiologic study was carried out on 77 TMD patients with degenerative joint disease who had visited the Orofacial Pain Clinic in Pusan National University Hospital. Al subjects were interviewed and examined clinically and radiologically using a standardized examination form. As related to gender and duration, subjective and objective sysmptoms in DJD patients were studied. The obtained results were as follows : 1. There were much more patients in the twenties or thirties, women and histories such as chronic duration and microtrauma. 2. Most patients responded positively more often to the questions of jaw function, unilateral chewing in habits, poot appetite and depression in behavioral response and shoulder pain in worsening prognosis 3. While the most common reasons for treatment were pain, noise, and limitation of opening, the associated symptoms such as headache, neckache, earache, jaw dysfunction, neck dysfunction, acute bite change and dizziness, ringing or fullness in the ears as secondary CNS excitatory effects were complained. 4. Opening the mouth in 25 to 40mm, soft end feel and deflective incisal pathway were seen and more tenderness to lateral or dorsal capsule of joint than intra or extra oral muscles were complained. 5. While there appeared no click, crepitus and single click in acute group, in chronic group, crepitus, single click and no click appeared in order of sequence. 6. Tomogram or bone scan revealed more bony changes than panorama and transcranial view.

• Clinical and Experimental Pediatrics
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• 제57권6호
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• pp.292-296
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• 2014

The deletion of the distal long arm of chromosome 1 is associated with a characteristic facial appearance and a pattern of associated malformations. Characteristic manifestations include a round face with prominent 'cupid's bow' and downturned corners of the mouth, thin vermilion borders of lips, a long upper lip with a smooth philtrum, a short and broad nose, epicanthal folds, apparently low-set ears, micrognathia, microcephaly, abnormal hands and feet, variable cardiac or genital anomalies, moderate to severe mental retardation, and growth retardation. Using fluorescent in situ hybridization (FISH) analysis to map precisely the deletion, we present a case of chromosome 1q44 deletion with craniofacial characteristics, multiple congenital anomalies, and growth and psychomotor retardation. In comparison with other reported cases of 1q43-44 deletion, the subject does not show hydrocephalus, seizure, syn- or polydactyly of hands, and a urogenital anomaly. However, an arachnoid cyst, pinpoint dimple on the midline of the forehead, a right-sided supernumerary nipple and auricular pit, polydactyly of the right foot, adducted thumb, and flexion restriction of the proximal interphalangeal joint with a simian line in both hands were observed additionally.