• Journal of Audiology & Otology
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• 제23권3호
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• pp.153-159
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• 2019

Background and Objectives: We aim to explore the effects of residual auditory steady state response (ASSR) on cochlear implantation (CI) outcomes in children lacking auditory brainstem responses (ABRs). Subjects and Methods: We retrospectively reviewed the data of child CI recipients lacking ABRs. All ears were divided into two groups: with residual ASSR and without ASSR. For each frequency, the T- and C-levels and the electrical dynamic ranges of postoperative 3-month and 1-year mappings were compared between the groups. To evaluate speech perception, patients who received simultaneous bilateral CIs were divided into two groups: group 1 exhibited responses at all frequencies in both ears; in group 2, at least one ear evidenced no response. The Categories of Auditory Perception (CAP) and Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS) scores were compared between the groups. Results: We enrolled 16 patients. At 2 kHz, the postoperative 3-month and 1-year T-levels of patients with residual hearing were lower than those of hearing loss group (p=0.001, p=0.035). In residual hearing group, the ASSR threshold correlated positively with the postoperative 1-year T-level (p=0.012, R²=0.276) and C-level (p=0.002, R²=0.374). Of 10 simultaneous bilateral CI recipients, 5 exhibited ASSRs at all frequencies and the other 5 showed no response at ≥1 frequency. The latter had higher CAP scores at the postoperative 1-year (p=0.018). Conclusions: In children exhibiting hearing loss in ABR testing, residual hearing at 2 kHz ASSR correlated positively with the post-CI T-level. Those with ASSRs at all frequencies had significantly lower CAP scores at the postoperative 1year. CI should not be delayed when marginal residual hearing is evident in ASSR.

• 대한청각학회지
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• 제23권3호
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• pp.153-159
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• 2019

Background and Objectives: We aim to explore the effects of residual auditory steady state response (ASSR) on cochlear implantation (CI) outcomes in children lacking auditory brainstem responses (ABRs). Subjects and Methods: We retrospectively reviewed the data of child CI recipients lacking ABRs. All ears were divided into two groups: with residual ASSR and without ASSR. For each frequency, the T- and C-levels and the electrical dynamic ranges of postoperative 3-month and 1-year mappings were compared between the groups. To evaluate speech perception, patients who received simultaneous bilateral CIs were divided into two groups: group 1 exhibited responses at all frequencies in both ears; in group 2, at least one ear evidenced no response. The Categories of Auditory Perception (CAP) and Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS) scores were compared between the groups. Results: We enrolled 16 patients. At 2 kHz, the postoperative 3-month and 1-year T-levels of patients with residual hearing were lower than those of hearing loss group (p=0.001, p=0.035). In residual hearing group, the ASSR threshold correlated positively with the postoperative 1-year T-level (p=0.012, R²=0.276) and C-level (p=0.002, R²=0.374). Of 10 simultaneous bilateral CI recipients, 5 exhibited ASSRs at all frequencies and the other 5 showed no response at ≥1 frequency. The latter had higher CAP scores at the postoperative 1-year (p=0.018). Conclusions: In children exhibiting hearing loss in ABR testing, residual hearing at 2 kHz ASSR correlated positively with the post-CI T-level. Those with ASSRs at all frequencies had significantly lower CAP scores at the postoperative 1year. CI should not be delayed when marginal residual hearing is evident in ASSR.

• Fibers and Polymers
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• 제6권3호
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• pp.219-223
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• 2005

Water-soluble chitin (WSC) was prepared by carefully deacetylating chitins to about $50\%$ of N-acetyl content. Topical formulations based on WSC were prepared and their effects on wound healing were evaluated on a rabbit ear model. Full-thickness, open skin wounds were made on the ears of rabbits and WSC ointments were embedded in the open wounds. The application of WSC ointments significantly accelerated wound healing and wound contraction. The areas of epithelial-ization and granulation tissues in WSC ointment group are remarkably larger than those in control group (no treatment) and in placebo group (treated with ointment-base materials). A large number of grown granulation tissues including dense fibroblast deposition were observed under the thickened epithelium of the wound treated with WSC ointments. The number of inflammatory cells in WSC ointment group was significantly decreased compared with those in control and placebo groups, indicating that WSC would give low stimuli to wounds and prevent excessive scar formation. Neovascularization was the most prominent in WSC ointment group. Wound contraction in WSC ointment group was much larger than those in control and placebo groups. Overall results demonstrate that the topical formulation based on WSC is considered to become an excellent dressing as a wound healing assistant.

• 대한한방내과학회지
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• 제21권3호
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• pp.487-493
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• 2000

Objective : This experimental studies were done to research the effects of Bojungikgi-tang added Magnoliae Flos on the pulmonary thromboembolism and delayed allergy response. Methods : Healthy rats were devided into each group. This test is to inject sodium arachidonic acid to one group, and ADP(adenocine diphophate) to the other one afterward to compare the survival rate between each other. Delayed allergy response test is to inject PC(picryl chloride) to one group and measure the thickness of their ears, to inject SRBC(sheep red blood cell) allergen to the other, and measure their foot edema, and compare the each other rates Results : The extract of the Bojungikgi-tang added Magnoliae Flos revealed significant effect on the pulmonary thromboembolism induced by sodium arachidonate, or adenocine diphophate(ADP). And the extract of the Bojungikgi-tang added Magnoliae Flos revealed significant effect on delayed type hypersensitivity induced by picryl chloride(PC), or sheep red blood cell(SRBC). Conclusions : According to the above findings it is suggested that the extract of the Bojungikgi-tang added Magnoliae Flos revealed significant effect on the delayed type hypersensitivity and effect on the pulmonary thromboembolism.

• Toxicological Research
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• 제24권3호
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• pp.189-194
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• 2008

The effects of DHU001, a mixed herbal formula consisted of 7 types aqueous extracts for treating respiratory disorders were observed on xylene-induced acute inflammation. The xylene was topically applied 60 min after administration of 500, 250 and 125 mg/kg of DHU001, and all animals were sacrificed 2 hrs after xylene application. The changes on ear weights, histolopathological analyses of ear were evaluated and compared to those of indomethacin and dexamethasone(15 mg/kg treated)-Both of drugs are well-known by anti-inflammatory agents. Xylene application resulted in marked increases in induced ear weights as compared with intact control ear. Severe vasodilation, edematous changes of ear skin and increase in the thickness of the ear tissues, neutrophil infiltration as acute inflammation were detected in xylene-treated control ears at histopathological observation. However, these xylene-induced acute inflammatory changes were dose-dependently decreased by oral treatment of DHU001. Therefore, it is concluded that DHU001 has favorable anti-inflammatory effects on xylene-applicated acute ear inflamed mice.

• 패션비즈니스
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• 제17권4호
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• pp.90-106
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• 2013

This study investigated the development of eyeglasses and design transition in materials and types through literature survey. The scope of this study on the basis of the 15th century, for this study survey reaches from the 15th century to modern. The result of this study were as follows. Real magnifying glasses was first mentioned by the Arab physicist al-Hazen who was famous of his treatise on optics. The oldest documents which explicitly refer to the art of making lenses for eyeglasses and magnifying glasses were the Venetian artisans of 1300. In the 15th century someone thought to remedy the unstability of glasses by securing the bridge on the forehead. But it was only in the 17th century that someone contrived to stabilize the frame by strapping it on the face by means of fine cords that reached behind the ears. Eventually in the early years of the 18th century the English optician Edward Scarlett invented the rigid earpieces which solved once and for all the problem of holding the eyeglasses firmly in place. In the 19th century, eyeglasses' fashion were monocle and pince-nez. In the 20th century, various lenses and frames were appeared. Therefore eyeglasses to correct defective sight, sun-glasses, as well as a most succesful item among modern fashion accessories.

• 한국전자통신학회논문지
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• 제5권3호
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• pp.251-255
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• 2010

본 연구에서는 단일 주파수에서의 선행음과 후속음이 음원의 방향지각에 미치는 영향을 조사하였다. 실험은 자극간격 시간과 레벨차를 가진 1kHz 순음을 사용하였으며 기준음의 제시시간은 10ms로 하였다. 좌우 귀에 도달하는 시간차는 0.5ms로 두었다. 하나의 자극간격 시간에 대하여 4종류의 레벨차를 두었으며 제시음이 제시된 후 음이 좌에서 들리는지 우에서 들리는지를 판단하도록 하였다. 그 결과 후속음보다는 선행음이 음상정위에 미치는 영향이 크다는 것을 알 수 있었다.

• Animal Bioscience
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• 제35권7호
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• pp.949-954
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• 2022

Objective: The present study is aimed at phenotypic characterization and mitochondrial d-loop analysis of indigenous "Diara" buffalo population, which are mostly confined to the villages on the South and North Gangetic marshy plains in the Bihar state of India. These buffaloes are well adapted and are best suited for ploughing and puddling the wet fields meant for paddy cultivation. Methods: Biometric data on 172 buffaloes were collected using a standard flexible tape measure. Animals are medium in size; the typical morphometric features are long head with a broad forehead and moderately long and erect ears. Genomic DNA was isolated from unrelated animals. The mtDNA d-loop 358-bp sequence data was generated and compared with 338 sequences belonging to riverine and swamp buffaloes. Results: Based on the mitochondrial d-loop analysis the Diara buffaloes were grouped along with the haplotypes reported for riverine buffalo. Sequence analysis revealed the presence of 7 mitochondrial D loop haplotypes with haplotype diversity of 0.9643. Five of the haplotypes were shared with established swamp breeds and with Buffalo population of Orissa in India. Conclusion: Morphometric analyses clearly shows distinguishing features like long and broad forehead which may be useful in identification. The germplasm of Diara buffalo is much adapted to the marshy banks of river Ganga and its tributaries. It constitutes a valuable genetic resource which needs to be conserved on priority basis.

• 한국토양비료학회지
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• 제3권1호
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• pp.1-10
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• 1970

수도(水稻)에 있어서 가리(加里)의 시용(施用)이 규회석(珪灰石)의 효과에 미치는 영향(影響)을 밝히기 위(爲)하여 Pot시험(試驗)을 실시(實施)하고 정조수량(精租收量)을 증가(增加)시킨 원인(原因)을 수량(收量) 및 수량구성요소(收量構成要素)와 수도(水稻)의 생육시기별(生育時期別) 토양(土壤) 및 식물체분석성적면(植物體分析成績面)에서 검토(檢討)한 결과(結果)를 요약(要約)하면 다음과 같다. 1. 가리(加里)의 효과는 규회석(珪灰石)이 시용(施用)되었을 때에 더 커지며 규회석(珪灰石)의 시용량(施用量)이 많을수록 가리(加里)의 요구량(要求量)도 많아진다. 2. 가리(加里)와 규회석(珪灰石)의 시용(施用)은 토양(土壤) 및 고중(藁中)의 가리(加里), 석회(石灰) 및 규산(珪酸)의 농도(濃度)를 증가(增加)시키며 $SiO_2/N$ 및 $K_2O/N$의 비율(比率)을 높여 정조수량(精租收量)을 증가(增加)시켰다. 3. 규회석(珪灰石)을 300kg/10a 이하(以下) 시용(施用)하였을 때에는 가리(加里)는 8kg/10a 에서 수량(收量)이 제일 높았으나 규회석(珪灰石)이 600kg/10a 시용(施用)되었을 때에는 가리(加里) 16kg/10a에서 수량(收量)이 제일 높았다. 4. 규회석(珪灰石)의 시용(施用)은 주당수수(株當穗數)와 수당립수(穗當粒數)는 감소(減少)시키고 등숙율(登熟率)과 천립중(千粒重)은 증가(增加)시키는 경향(傾向)이며 규회석(珪灰石) 시용(施用)으로 증가(增加)된 고중(藁中)의 CaO와 $SiO_2$는 주당수수(株當穗數)와 수당립수간(穗當粒數間)에는 부(負)의 상관(相關)이었으나 등숙율(登熟率)과 천립중(千粒重)과는 정(正)의 상관(相關)이 있었다. 5. 가리(加里)의 시용(施用)은 주당수수(株當穗數)와 수당립수(穗當粒數)를 증가(增加)시키는 경향(傾向)이며 가리시용(加里施用)으로 증가(增加)된 고중(藁中)의 $K_2O$와 수당립수(穗當粒數)와는 정(正)의 상관(相關)이 있었다. 6. 질소(窒素)의 흡수량(吸收量)은 가리(加里)와 규회석(珪灰石)의 시용(施用)이 증가(增加)함에 따라 감소(減少)하는 경향(傾向)이며 $SiO_2/N$ 비율(比率)은 가리(加里)와 규회석(珪灰石) 시용량(施用量)이 증가(增加)할수록 증가(增加)한다. 7. $K_2O/N$ 비율(比率)은 가리(加里)를 시용(施用)할수록 증가(增加)되며 가리무시용구(加里無施用區)에서는 규회석(珪灰石) 시용량(施用量)에 따라 감소(減少)하였다.

• 한국작물학회지
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• 제68권4호
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• pp.392-401
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• 2023

본 연구에서는 농업부산물인 옥수수 속대의 생리활성 화합물 공급원으로의 잠재적 활용 가능성을 탐색하기 위해 이삭의 성숙 단계에 따른 phytosterol 함량 변화를 측정하였다. 1. 옥수수 이삭의 crude fat 함량 변이는 속대가 3 DAS에서 54 DAS까지 2.51±0.06-0.33±0.04%, 종실은 9 DAS에서 54 DAS까지 1.84±0.04-4.91±0.28%로 나타났으며 종실은 성숙할수록 crude fat 함량이 증가하였고 속대는 반대의 경향을 나타내었다. 2. 옥수수 이삭의 등숙 기간 동안 속대와 종실에서 campesterol, stigmasterol, β-sitosterol은 주요 phytosterol로 검출되었으며, total phytosterol 함량은 속대가 3 DAS에서 54 DAS까지 134.84±4.58-48.86±0.89 mg/100g DW, 종실은 9 DAS에서 54 DAS까지 83.15±2.74-42.12±0.08 mg/100g DW로 생리적 성숙 초기 단계에 가장 높은 함량을 보인 뒤 점차적으로 감소하였다. 3. Hierarchical clustering heatmap analysis와 principal component analysis에서 옥수수 속대와 종실은 생리적 성숙 단계 및 조직 부위에 따라 구분이 되었다. 옥수수 속대를 새로운 phytosterol 공급원으로써 활용하기 위해 함량이 가장 풍부한 시기는 R1-R2 stage이며, 이삭 성숙 전체 단계에서 속대에는 종실보다 많은 phytosterol이 존재하므로 농업부산물인 속대를 새로운 phytosterol 공급원으로 활용할 수 있을 것이다.