• Title/Summary/Keyword: Early stopping

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The Effect of Platelet Rich Plasma Combined with Bovine Bone on the Treatment of Grade II Furcation Defects in Beagle Dogs (성견 2급 치근이개부 병변 치료시 이종골 이식 및 혈소판 농축 혈장의 골재생에 관한 효과)

  • Lim, Sung-Bin;Lee, Kwang-Soo;Park, Young-Chae;You, Hyung-Keun;Shin, Hyung-Shik
    • Journal of Periodontal and Implant Science
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    • v.30 no.2
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    • pp.257-277
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    • 2000
  • New techniques for regenerating the destructed periodontal tissue have been studied for many years. Current acceptable methods of promoting periodontal regeneration are basis of removal of diseased soft tissue, root treatment, guided tissue regeneration, graft materials, and biological mediators. Platelet Rich Plasma has been reported as a biological mediator which regulates activities of wound healing progress including cell proliferation, migration, and metabolism. The purpose of this study is to evaluate the effects of using the Platelet Rich Plasma as a regeneration promoting agent for furcation involvement defect. Five adult beagle dogs were used in this experiment. The dogs were anesthetized with Ketamin HCl(0.1 ml/kg, IV)and Xylazine hydrochloride($Rompun^{(R)}$, Bayer, 0.1 ml/kg, IM) and conventional periodontal prophylaxis were performed with ultrasonic scaler and hand instruments. With intrasulcular and crestal incision, mucoperiosteal flap was elevated. Following decortication with 1/2 high speed round bur, degree II furcation defect was made on mandibular third(P3), forth(P4) and fifth(P5) premolar, and stopping was inserted. After 4 weeks, stopping was removed, and bone graft was performed. Ca-P was grafted in P3(experimental group I), Combination of Ca-P and plasma rich platelet were grafted in P4(experimental group II), and P5 was remained at control group.Systemic antibiotics(gentamicin sulfate)and anlgesics(phenyl butazone) were administrated intramuscular for 2 weeks after surgery. Irrigation with 0.1% Chlorhexidine Gluconate around operate sites was performed during the whole experimental period except one day immediate after surgery. Soft diets were fed through the whole experiment period. After 4, 8 weeks, the animals were sacrificed by perfusion technique. Tissue block was excised including the tooth and prepared for light microscope with Gomori's trichrome staining. At 4 weeks after surgery, there were rapid osteogenesis phenomenon on the defected area of the Platelet Rich Plasma plus Ca-P BBP group and early trabeculation pattern was made with new osteoid tissue produced by activated osteoblast. Bone formation was almost completed to the fornix of furcation by 8 weeks after surgery. In conclusion, Platelet Rich Plasma can promote rapid osteogenesis during healing of periodontalregeneration.

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Lung Detection by Using Geodesic Active Contour Model Based on Characteristics of Lung Parenchyma Region (폐실질 영역 특성에 기반한 지오데식 동적 윤곽선 모델을 이용한 폐영역 검출)

  • Won Chulho;Lee Seung-Ik;Lee Jung-Hyun;Seo Young-Soo;Kim Myung-Nam;Cho Jin-Ho
    • Journal of Korea Multimedia Society
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    • v.8 no.5
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    • pp.641-650
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    • 2005
  • In this parer, curve stopping function based on the CT number of lung parenchyma from CT lung images is proposed to detect lung region in replacement of conventional edge indication function in geodesic active contour model. We showed that the proposed method was able to detect lung region more effectively than conventional method by applying three kinds of measurement numerically. And, we verified the effectiveness of proposed method visually by observing the detection Procedure on actual CT images. Because lung parenchyma region could be precisely detected from actual EBCT (electron beam computer tomography) lung images, we were sure that the Proposed method could aid to early diagnosis of lung disease and local abnormality of function.

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The Korean Fricatives in Acquisition: A Case Study

  • Kang, Kyung-Shim
    • Speech Sciences
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    • v.11 no.2
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    • pp.71-87
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    • 2004
  • Korean has a pair of voiceless fricatives, whose laryngeal manifestation comes in parallel to stops and affricates with a three-way lexical contrast. Prior phonetic studies by Kagaya (1974), Iverson (1983), and Kang (1999, 2000) point out /s/ is associated with multiple characteristics of the larynx shared with not only the lax but also the aspirated series, whereas /s' / carries a laryngeal distinction typical of the tense consonants. The complex dual nature of /s/ is again supported by a psycholinguistic study by Kang (2004), as /s/ was found to interact with /$c^h$/ (17% of the time) as well as /c/ (57%) in speech errors. In addition, a recent work by Cho and Lee (2003) notes an interesting chain shift case in the acquisition of the fricatives. Although they observed a significant phonological pattern between child English and Korean, Cho and Lee's description of acquiring fricatives is far from being precise from the perspective of phonetics. From a longitudinal study of recorded tapes by two children at 1;7-3;8 and 1;7-2;1 respectively, I found that /s' / was usually substituted into tense noncontinuants in young children's early production as predicted, whereas /s/ having both lax and aspirated-like glottal properties revealed a complicated pattern of substitutions into lax, tense, and aspirated noncontinuants with a varying degree of preference relative to the subjects. The current acquisition study supports the previous claims concerning fricatives in other languages, showing that their acquisition comes after stops. Besides, it also notes that Korean fricatives are subject to a series of phonological processes called stopping, affricating, tensifying and palatalizing during the transitional period of phonological development by young children. Moreover, between the two voiceless types, /s/ was acquired earlier than /s'/ as the unmarked segment.

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Effects of Prohexadione-Ca, Ethephon, and Water Stress on Growth and Productivity of 'Golden Delicious'/M.9 Apple

  • Guak, Sunghee
    • Horticultural Science & Technology
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    • v.31 no.1
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    • pp.38-49
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    • 2013
  • Prohexadione-calcium (Pro-Ca), ethephon and transient water stress were evaluated in a factorial design, as potential inhibitors of early-season shoot growth of high density orchard management of apple (Malus domestica Borkh.) trees. In the experiment, water stress was imposed to one-half of the 7-year-old 'Golden Delicious'/M.9 apple trees in each of 5 blocks, by stopping irrigation for 3 weeks between 35 and 56 days after full bloom (AFB). Within each whole unit, the following Pro-Ca and ethephon treatments were randomly allocated at $2{\times}2$ factorial: a) 0 or 250 $mg{\cdot}L^{-1}$ a.i. Pro-Ca applied at 28 days AFB and b) 0 or 300 $mg{\cdot}L^{-1}$ a.i. ethephon applied twice (35 and 71 days AFB). All trees were hand thinned to king flowers prior to treatments. Vegetative shoot growth was markedly reduced by Pro-Ca, with its effect being obvious within 14 days after application, while ethephon and water stress treatments were less effective. Pro-Ca had no effect on fruit set and yield but slightly increased fruit size. Ethephon substantially reduced the fruit size and yield but had no effect on fruit set. Water stress reduced fruit set, fruit size and yield. With regard to fruit quality, Pro-Ca did not influence fruit shape, flesh firmness and soluble solids contents (SSC) but slightly reduced titratable acidity. Ethephon had no effect on fruit shape but increased firmness, SSC and acidity, while water stress did not influence these fruit quality attributes. Dry weight of dormant spur buds was reduced by both Pro-Ca and water stress, while increased by ethephon. The larger dormant buds led to the larger spur flowers at the tight cluster stage the following spring. Return flowering was promoted only by ethephon, especially on previous season's shoots. There were no significant interactions between Pro-Ca and ethephon or water stress on most variables observed in this study.

A Study on Influences of Waterproofing Admixtures for Concrete on Self-Healing Properties of Hardened Cement Paste (시멘트페이스트 경화체의 Self-Healing 특성에 미치는 구체방수재의 영향)

  • Kim, Jae-Young;Byun, Seung-Ho;Ma, Sang-Jun
    • Journal of the Korea Concrete Institute
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    • v.20 no.1
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    • pp.109-116
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    • 2008
  • This study was performed to get information of self-healing mechanism in cement system and the influence of waterproofing admixtures for concrete on self-healing property. For testing, cement paste specimens cured for 7, 14 and 28 days were prepared and crushed into plate-shape pieces. Screened specimens with thickness not more than 1mm were covered with wet rags and cured in a plastic container for 7 and 28 days. After stopping hydration process of the specimens by treatment with acetone, the surfaces of specimens have been contacted with wet rags were analyzed by XRD, DSC, SEM and EDX. The analysis results showed that cement paste has self-healing property and this property is mainly affected by water. Self-healing in cement system is more effective and faster at an early stage of hydration as there is enough content of unreacted cement to make an additional hydration in this period. The results of this study also showed that waterproofing admixtures for concrete have a considerable effect on self-healing of cement pastes; i.e., they improved self-healing effect of cement and, especially, the specimen using admixture C has shown a lot of needle-like or fibrous hydration products which are estimated as ettringite. It is supposed that these ettringite products are effective to enhance self-healing in cement system.

지역사회 건강관리담당자의 만성질환 관리실태:전라남도를 중심으로

  • Kim, Hye-Sook;Park, Jong;Jeong, Eun
    • Journal of agricultural medicine and community health
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    • v.34 no.3
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    • pp.334-345
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    • 2009
  • Objectives: This study was performed to investigate the management status of chronic disease at community health centers. Methods: The study subjects were 450 employed persons at community health centers in Jeonlanamdo. General characteristics, status of chronic disease management and health education were collected for statistical analysis. The differences on management status among working areas were assessed with chi-square test and ANOVA. Results: The mean values of work duration were 18.7 years in rural, 14.4 years in fishing village, and 17.4 years in urban-rural, respectively. The number of management registration was highest in hypertension. The ways of disease management were medication check-up, diet stopping smoking. The contents of group health education were exercise, diet and prohibition of smoking. The place of health education was town assembling hall. The fields which officials wanted to be educated were symptom, diagnosis, treatment and complication. The most important field was early detection of chronic disease patients and health education. Finally, the field requiring support was work standardization. Conclusions: Community health workers have worked positively in chronic disease management. The barriers to work were the lack of professional and preliminary data. The support system with other health organ and health education were needed for the improvement of working ability.

우리나라 농촌지역의 출산조절행태 및 출산조절행위의 결정요인 분석

  • Chung, Kyung-Hee;Han, Seung-Hyun;Bang, Sook
    • Korea journal of population studies
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    • v.11 no.2
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    • pp.33-53
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    • 1988
  • This study aimed at developing a desirable family planning policy and strategy by examining the current status of family planning practice in rural Korea and by indentifying the crucial factors which affect fertility control behavior. For this purpose, an analytical study was conducted, using the survey data collected in July 1985, on an interview basis, on 1, 440 married women living in the Soyi, Wonnam and Maingdong townships of Eumseong County(in North Chungcheong Province). This study population has the typical characteristics of rural areas, and the results of the analysis can be summarized as follows: 1. In regard to the demographic characteristics of the study population : their average age at marriage was 23.7, they had an average of 2.6 children( 1.3 boys, 1.3 girls) :10% experienced the death of their child (ren) :14% had spontaneous abortion(s) :4% weathered stillbirth(s) :35% went through induced abortion (s) : and 5.5% were currently pregnant. The average of their ideal numbers of children was 2.2, while 44% felt that they must have a son. 2. Looking at the contact rate with medical & health institutions, over the past 1 year, the visit rate to health subcenters was 43.7%, while 26.9% visited the (county) health center :59.6% had been to private clinics : and 41.5% went to the Soonchunhyang - Eumsung hospital : thus showing a relatively high rate of accessibility. 3. The utilization rate of family planning services was 76.5%, with tubectomy being the most prominent method at 52.3%, while the informants were health workers in 54.2% of the acceptors. Of the 8.4% who discontinued the use of contraceptive methods, only 26% did so due to want for pregnancy, natural infertility (meno - pause), or other reasons, while the remaining 74% stopped usage on account of side effects, failure in the methods themselves, and inconvenience of use, thus pointing to a situation where the proper choice of family planning methods have not yet been made. It can be noted that there is a strong motivation for early birth stopping as 35.3% practice family planning even with only one child, of which 38.3% have had sterilization operations. According to results of a multiple regression analysis, among the variables affecting contraception usage the most significant variable was the number of sons. 4. 34.8% experienced induced abortions. It was shown as a result of multiple regression analysis that the number of children and attitudes toward induced abortions extensively affected their frequency of abortions conducted. 5. In the regard to the relation between family planning and induced abortions, 33.7% of the women used both, while 52.0% of them used only the former(family planning), with only 1.4 % utilizing solely the latter(abortion), and 12.9% totally abstaining from fertility regulation : again, the discriminant analysis indicated that the choice of family planning and/or induced abortion was determined by the number of children and attitudes toward induced abortion. In view of the above mentioned results, the following are some comments and suggestions concerning problems related to the current family planning policies, in Korea : 1. It is difficult to expect a further quantitative expansion in family planning program operations, as there has been an excessive supply of target-oriented sterilization operations on women. From a maternal and child health care point of view, it will be desirable to have a diversification of service points in the future where family planning methods may be properly chosen, so that choices of methods which suit the mothers' characteristics and tastes may be made by the individuals themselves by strengthening their quality of family planning information services. 2. Along with the strengthening of the qualitative improvement of family planning services policies must be implemented to effectively promote the moral (ethical) deterrents to induced abortions and to preference for sons. From a maternal care standpoint, the social permissive norm toward induced abortion must be modified, and the bias towards son must be analyzed as the women with more daughters have a lower rate of family planning acceptance. Such changes in attitudes, however, can not be hoped to be accomplished with ad hoc policies, but will only be possible when an enhancement of the women's status(within the society) is brought about in a long - term perspective.

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