• Pediatric Infection and Vaccine
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• v.13 no.1
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• pp.63-70
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• 2006

Purpose : We hypothesized that mannose binding lectin gene(MBL2), a key molecule of innate immunity, may contirbute to the development and the outcome of respiratory syncytial virus(RSV) disease in early childhood. This study was performed to investigate the genetic basis of polymorphisms and haplotypes of MBL2 for RSV disease severity in Korean children. Methods : Cases with severe RSV diseases are 99 children with severe RSV lower respiratory tract infections, who were admitted to the Seoul National University Children's Hospital through 1993~2000. The control subjects consisted of 224 anonymous healthy Korean blood donors. The frequency of promoter variant(-221, X/Y) and structural variant(codon 54) were compared between the case patient group and the control subject group. Results : The mean age of patients was 11.8 months; 49% were <6 months, 39% were 6-24 months and 12% were >24 months. In the cohort of cases of severe RSV diseases, the genotypic frequencies of structural variant in codon 54 were 61% for AA, 34% for AB, and 5% for BB. Those of the promoter X/Y variant were 85% for YY and 15% for XY. There were no significant differences in overall distribution of both structural and promoter variants between the cases and the control subjects. We did not observe statistical difference in the haplotypic frequencies of MBL2. Conclusion : Common variants of MBL2 gene most likely do not contribute to the risk for severe RSV diseases in Korean children. Further genetic association studies should be conducted in a larger propsectively recruited cohort of children with RSV infection.

• Journal of Chest Surgery
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• v.32 no.5
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• pp.413-421
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• 1999

Background: Ischemia reperfusion injury is known to contribute to the major causes of the early graft failure in lung transplantation. Triiodothyronine (T3) has been suggested to ameliorate ischemia reperfusion injury from both in vivo and in vitro experiments of various organs. Prospecting its beneficial effect for pulmonary allograft preservation, we made a new solution by adding T3 into the extracellular type dextran solution. Material and Method: Twelve adult mongrel dogs underwent left lung allotransplantation. Six donor dogs were flushed with the new solution(Group 1, n=6), and the remaining six were flushed with Euro-Collins solution to serve as controls(Group 2, n=6). Allografts were stored in each preservation solution for 20 hours at 4$^{\circ}C$. Left single lung transplantations were performed. The right pulmonary artery and the right main bronchus were clamped at 15 minutes after the reperfusion and maintained throughout the experiment to evaluate the transplanted left lung function. Result: Arterial carbon dioxide tension was better in group 1 than in group 2 throughout the experiment period and the difference was statistically significant at 2 hours after reperfusion(28.0${\pm}$3.0 mmHg and 53.1${\pm}$17.4 mmHg, p<0.05). The differences of arterial oxygen partial pressure, peak airway pressure and pulmonary vascular resistance showed no statistical significance. The malondialdehyde(MDA) level, measured from tissue obtained at 120 minutes after reperfusion showed no statistically significant difference. The tissue wet/dry ratio of group 1(649${\pm}$27 %) was significantly lower than that of group 2(686${\pm}$71 %, p<0.05). The microscopic examination revealed varying degrees of injury represented mainly by findings such as perivascular neutrophil infiltration, capillary hemorrhage and interstitial congestion. These findings were less severe in group 1 than those in group 2. Conclusion: The new solution demonstrated superior allograft preservation after 20 hour ischemia compared to Euro-Collins solution in canine single left lung transplantation model, these results suggest that T3 might be a promising agent for pulmonary allograft preservation.

• Journal of Korean Home Economics Education Association
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• v.23 no.3
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• pp.185-200
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• 2011

The purpose of this study was to investigate if these factors affect the correlation between the female adolescent interest in appearance and appearance management behavior with self-concept and sexual maturity. To achieve this, a survey was conducted for the female students in elementary and middle school in the Seoul area. The results of this study were as follows. 1. The comparison of students' interest in appearance and appearance management behavior showed that the middle school students showed higher scores in both matters. 2. Elementary students generally held more positive self-concept, with domestic self value shown statistically high 3. Tanner Stage 2.3. the early puberty stage, for elementary school students, and Tanner Stage 3.4. the growth and development stage, for middle school students. The percentage of students who had already entered menstruating turned out to be only 33% for elementary students but 90% for middle school students. Their subjective views of sexual maturity were also different as elementary students had negative feeling when they thought their sexual maturity were maturity were earlier than their peers' while middle school students were just the opposite. 4. The study on the impact of self-concept and sexual maturity on the interest in appearance of female students in elementary and middle school showed that elementary students had a higher interest in appearance that corresponded to the lower domestic self-concept and a higher social self-concept. On the other hand, middle school students showed higher interest in appearance, corresponding to their higher social self-concept, lower domestic self-concept, more negative feeling of sexual maturity, and higher feeling of physical self-concept. The study on the impact of interest in appearance, self-concept, and sexual maturity on the appearance management behavior of elementary and middle school female students revealed that elementary students with a higher interest in appearance were more enthusiastic about appearance management. Middle school students' appearance management behavior turned out to be higher, corresponding to their higher interest in appearance, lower domestic self-concept, and higher social self-concept.

• Journal of Korean Public Health Nursing
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• v.12 no.1
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• pp.132-146
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• 1998

This Study was attempted to provide the basic data necessary in the development and introduction of Home Health Nursing System by investigating the recognition and attitude level of Home Health Nursing System. The data were collected by means of questionaires presented to 74 patients who had been admitted in C general hospital in Chon Ju, from June 30, 1997. As the tool for this study, the questionares developed by Kim Yong. Soon, et al (1990) and Han Bok Hee(1993) were modified and supplemented for the aim of this study. The computer was used for data analysis. The items about the charateristics of the subjects and the attitude to the management plan of Home Health Nursing System were represented as the frequency and percentage. The standard deviation and calculation average were produced on the items related to definition, recognition, necessity, expected effect of the attitude of Home Health Nursing System and the items related to admission. The ANOVA test was .used according to the characteristics of variables to analyze the necessity and difference of Home Health Nursing System. The results of this study were as follows 1) The general characteristics of the subjects were as follows ; for sex, man, $58.1\%$ ; for age, 50-59 years, $29.7\%$ ; for the level of education, high school, $51.4\%$ ; $79.7\%$ of them were married; for the family forms, small family, $73.0\%$ ; and $68.9\%$ of them take the monthly income over 100 million won. 2) The characteristics related to admissions of the subjects were as follows ; for clinic, surgical department, $78.4\%$ ; addmission not more then 7days, $47.3\%$ ; for the operation-performance $71.6\%$ of them were experienced; for the admission route, via outpatients clinic, $54.1\%$ ; for waiting period to the admission day, 1-2 days, $71.6\%$. 3) The difficulties comming from the hospitalization were related mostly to the factor that they felt hospital life more inconvenient than home.(3.66) The reasons for the difficulties in the admission which was due to insufficient beds in the hospital was related to the concentration to the general hospital because of 'The Whole National Medical Insurance System'(4.05). 4) On the previous informations about the Home Health Nursing System, those who have heard of only the name were 42 $(56.8\%)$, and on the recognition of it, they thought that it is periodic treatment by the licenced nurses for the recovering pateints after early discharge(3.73). On the attitude about the necessity of Home Health Nursing System, they thought that it is necessary because of the increasing trend of a psychological disease by the change of environment and complexity of the social structure(4.24). On the expected effect of Home Health Nursing System, they answered that it is convinient for the family of the patient to take care of them(4.l8). 5) On the attitude to the management plan of the Home Health Nursing System, those who had intention to participate in the system in the case of systemic support were 42(56.8). In the visiting time, 'visit periodically' and 'visit when the patient needs' were $28(37.8\%)$ respectively. For the application of medical insurance, if possoble, they will use $(91.9\%)$; for the method of payment for the treatment, 'pay by the time required' was $23(31.1\%)$, for the subject of management, 'National public institute must operate' was $33(44.6\%)$. 6) The relationship between the general characteristics of the subjects and the necessity of Home Health Nursing System showed the notable difference in the age (F=3.508, P<0.05) and marrage state (F=5.402, P<.023).

• Clinical and Experimental Pediatrics
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• v.49 no.5
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• pp.507-512
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• 2006

Purpose : Early detection and intervention of hearing impairment is believed to improve speech and language development and behavior of children. The aim of this preliminary study was to determine the prevalence of hearing impairments, and to identify the association of risk factors relating to refer response in high risk neonates who were screened using distortion product otoacoustic emissions (DPOAE). Methods : The subjects included 871 neonates who were admitted to the neonatal intensive care unit of the Pediatric Department in Soonchunhyang University Bucheon Hospital from May, 2001 to December, 2004. They were screened using DPOAE. Based on DPOAE, we divided the neonates in two groups : 'Pass' and 'Refer'. The differences in risk factors between the pass group and the refer group were analyzed. Results : The incidence of the refer group was 12.1 percent(106 out of 871). The bilateral refer rate was 5.4 percent(47 out of 871). And the unilateral refer rate was 6.7 percent(59 out of 871). Gender, birth place, family history of hearing loss, small/large for gestational age, obstetrical factor, hyperbilirubinemia and use of gentamicin were not statistically related to the refer rate. Statistically related to refer rate were birth weight, resuscitated neonates, Apgar score, craniofacial anomaly, mechanical ventilator application, sepsis, using of vancomycin(P<0.05). The prevalence of hearing impairment (${\geq}60dB$) in this study was 2 percent(18 out of 871). Conclusion : This study showed a higher prevalence of hearing impairment in high-risk neonates. Thus neonatal hearing screening should be carried out in high-risk neonates.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.8 no.4
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• pp.9-23
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• 2013

'Entrepreneurship' spread like fashion, then it was a term that is no stranger to the youth. Entrepreneurship education for young people is being activated. Recently conducted many educational institutions, as well 'Bizcool' entrepreneurship education. Performance will be clear that the purpose of education and, where appropriate, external training. Currently operating business through 'Bizcool' homepage, 'Bizcool' budget is concentrated in high school. Entrepreneurship education are made aware of the need to equip the correct career awareness is spreading. Preliminary founder, as well as for students. Students will be more structured training support. And many more will be supported by the budget. Therefore, the present study is to analyze the impact of entrepreneurship education career awareness satisfaction. And try to give elementary school students, middle school students, high school students due to the difference in effective entrepreneurship education and ways to activate. The first result, entrepreneurship education training information satisfaction has a significant impact on the career awareness. Satisfaction of the second result, entrepreneurship education teaching methods have a significant impact on the career awareness. The third result, operating the way entrepreneurship education has a significant impact on the recognition of the career satisfaction. The difference between the fourth result, depending on the satisfaction of the entrepreneurship education, career awareness, depending on the level of education does not represent. This study, the results of entrepreneurship education has a positive impact on the career recognition. And have a positive 'Bizcool' education could help implication. However, did not differ according to the difference in student career awareness. So I think it would need more concrete preparation. Also want to provide entrepreneurship education opportunities to students based on the results of this study a little more evenly. Career awareness for students through entrepreneurship education from an early age who would establish the correct values. And students will have a huge impact on the development of the society. The purpose of this study was a survey of students who participated in the 2012 'Bizcool Camp'. This study derives meaningful results. But will need to be interpreted with caution. Some students are first surveyed who participated in the 2012 'Bizcool Camp'. Therefore, there is a limit to generalize the findings. Second, junior high school students surveyed rate is low. So there are limits to students representing the difference. Third, most survey respondents per participant. Therefore, the study subjects, as there is a limit. This study, the impact of career awareness, youth entrepreneurship education satisfaction were analyzed by student differences. The results of this study, more study will be needed for students.

• Parasites, Hosts and Diseases
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• v.23 no.1
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• pp.7-17
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• 1985

In order to determine the susceptible age of Enterobius vermicular is to anthelmintics and to observe the chronologie growth of female E. vermicularis in man, experimental infections were done. About 500 eggs were challenged to 19 volunteers. After 4, 8, 16, 20, 24, 28, 32 and 35 days of infection, each case was treated by either mebendazole or pyrantel pamoate. On the 40th day of infection all cases including control were treated again to terminate the experimental infection and to evaluate the effect of previous treatment. Each case collected 3-day stools to harvest the expelled worms. The results could be summarized as follows: 1. The infection rates of females were in range of 0.6~13.1 % in control cases. Because the collected worms showed comparable growth and development by day, the worms were concluded to be derived from experimental infection. 2. Cases that were treated with mebendazole on 4, 8 and 16 days after infection expelled 37.5%, 2.5% and 67.5% of the number expelled by a control case on the 40th day. Cases treated thereafter expelled no worms on the 40th day. 3. Cases that were treated with pyrantcl pamoates on 4, 8, 16, 24, 28, 32 and 35 days, expelled 90.7%, 25%, 45.3%, 8%, 2.7%, 5% and 29.3% of the number collected from control cases in respect. 4. All the worms collected were females. The total body length increased consistently and comparably from the 20th day of infection. Those collected on the 20th day were 2.5~3.0 mm long with vagina, sac-like structure and strands of ovaries; 24 day-old worms may have short uterus, 28 day-old worms had long uterus without eggs, 32 day-old worms began to produce eggs, 35 day-old worms showed wide variations in egg deposit in uterus, and 40 day-old worms had uterus filled with eggs from vulva to anal levels. From the above results, it was inferred that the life span of female Enterobius vermicularis was longer than 40 days, and the developmental stages of worms younger than 16 days resisted considerably to both mebendazole and pyrantel pamoate.

• Korean Journal of Psychosomatic Medicine
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• v.7 no.1
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• pp.124-133
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• 1999

Objective : Postpartum depression(PPD) was known to be caused by many factors including various psychosocial risk factors. This study was performed to identify the psychosocial risk factors for ppd, preliminarily in Korea. Methods : A group of 119 postpartum women, each of whom was at 6 to 8 weeks after delivery was identified at the time when they visited to the child health clinic or postnatal check-up clinic. The risk factors were surveyed by the self-reported questionnaire. The items of questionnaire were consisted of known risk factors in other studies and other possible stress-related factors. PPD was assessed by the Edinburgh Postnatal Depression Scale(EPDS) and the degree of postpartum depression was determined by its score. Results : 16 women(13.45%) in the high risk group were diagnosed as PPD among the 119 women. Risk factors including past experience of depressive symptoms and low level of marital satisfaction were founded more frequently in women in the high risk group than in the low risk group. The score of EPDS was significantly high in the group who experienced depressive symptoms in the past, anxiety or depression during pregnancy, stressful life event during the period of recent pregnancy and postpartum, and who had low level of marital satisfaction. There was a positive correlation between age and the score of EPDS. However, the postpartum depressive symptoms were not influenced by the level of education, job, retirement due to pregnancy and delivery, wanted or unwanted pregnancy, delivery method, feeding method, the hospitalization of infant, expected and real gender of infant. Conclusion : These results suggest that PPD is quite frequent at postpartum period. Various risk factors contribute to the development of PPD. If clinicians pay attention to the risk factors of PPD and give appropriate psychiatric intervention to the mothers during pregnancy and postpartum, it will be easy for the clinicians to recognize and treat PPD in the early stage.

• The Journal of Engineering Geology
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• v.28 no.2
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• pp.133-160
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• 2018

$CO_2$ storage is a very important technology for reduction of greenhouse gas emissions and has been considered as almost the only viable and effective option for immediate large-scale $CO_2$ sequestration. Small-scale demonstration project for offshore $CO_2$ storage in the Pohang Basin is the transitional stage R&D program for technological preparation of large-scale $CO_2$ storage project in Korea. Through the extensive exploration research for prospective $CO_2$ storage sites, the offshore strata in the Pohang Basin was recommended for the storage formation of the small-scale demonstration project. The Pohang Offshore Storage Project launched at 2013, and has accomplished the technical demonstration and technological independence in a wide range of $CO_2$ storage technology, such as geophysical exploration, storage site characterization, storage design, offshore platform construction, injection-well drilling and completion, deployment of injection facility, operation of $CO_2$ injection, and $CO_2$ monitoring. The project successfully carried out $CO_2$ test injection in early 2017, and achieved its final goal for technical development and demonstration of $CO_2$ storage in Korea. The realization of $CO_2$ injection in this project is the measurable result and has been recorded as the first success in Korea. The Pohang Offshore Storage Project has a future plan for the continuous operation of $CO_2$ injection and completion of $CO_2$ monitoring system. The project has provided in-house technical and practical expertises, which will be a solid foundation for the commercial-scale $CO_2$ storage business in Korea. Additionally, the project will help to secure national technical competitiveness in growing international technology market for $CO_2$ storage.

• Journal of The Korean Society of Grassland and Forage Science
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• v.8 no.2
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• pp.92-98
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• 1988

With a purpose of finding out the effects of magnesium and boron enriched organic-compound fertilizer application on the dry matter yield, yield components and changes in the botanical composition on the hilly pasture, a field experiment was arranged with five different treatments as a randomized block desigh and lasted from September, 1984 to the end of growing season in 1986. The results obtained are summarized as follows: 1. As a early plant growth and development, winter hardiness, growth vigour and coverate of grasses at the plots with organic-compound fertilizer application were better comparing to single dressing. 2. Average dry matter yields for two years were shown significantly high due to increasing amount of fertilizer. This trend was same both single and organic-compound fertilizer. And dry matter yields with organic-compound fertilizer application of low (8,693.1 kg/ha) and conventional level (12,758.7 kg/ha) were appeared to increase by 10 and 15% than those of single dressing of Low (7,930.6 kg/ha) and conventional level (11,122.6 kg/ha), respectively. But it was not significant difference. 3. Dry matter yield of grasses was significantly gained by increasing amount of fertilizer. The yield of legumes at the plots with organic-compound fertilizer application the yields of grasses were a litle more increased by 8-14%, and legumes were much more gained by 26-29% than those of the same species groups with single dressing, but it was not significant between the differnet kinds of fertilizer in the same fertilizing level. 4. At the grassland management, the rate of legumes tended to dominate at the plot without fertilization gradually. On the other hand, the botanical compositions and the rates of grasses were much better maintained at the plots with fertilization. But the rates of legumes with organic-compound fertilizer application tended to increase a little more than those of single dressing gradually. 5. All of the soil chemical properties after the experiment were much more improved comparing to before the experiment. But the average contents of soil organic matter and available $P_2O_5$ were slightly higher at the plot with organic-compound fertilization, on the other hand, pH and exchangeable cations tended to a little less than those of single dressing.