• Title/Summary/Keyword: Early action

Search Result 429, Processing Time 0.026 seconds

Relationship between Plasminogen Activity and Plasminogen Inhibitor during the Culture of Porcine Oviduct Epithelial Cells

  • Ahn, Shin-Hye;Cheong, Hee-Tae;Yang, Boo-Keun;Kim, Dae-Young;Park, Choon-Keun
    • Reproductive and Developmental Biology
    • /
    • v.33 no.4
    • /
    • pp.203-209
    • /
    • 2009
  • The present study was performed to identify changes of plasminogen activator (PA) and plasminogen activator inhibitor (PAI) in porcine oviduct epithelial cells (POECs) during the estrous cycle. POECs obtained from ovary in pre-ovulatory (Pre-Ov), early to mid-luteal stage (Early-mid L) and post-ovulatory stage (Post-Ov). For the examine of PA activity, $1{\times}10^5$ fresh cells of POECs were cultured in DMEM/Ham F-12 containing 10% FBS and 0.2% amphotericin under humidified atmosphere of 5% $CO_2$ in air and $38^{\circ}C$. The urokinase-type PA (uPA) was observed at 7 days of POECs culture. PA activity was measured with culture prolonged of 0, 3, 6, 12 and 24 h after culture of 7 days. The PA activity were high significantly (p<0.05) at 12 h of culture, but PA activity were decreased with culture periods increased. The PA activity in POECs of Post-Ov stage were higher significantly (p<0.05) than that of Early-mid L and Pre-Ov stage. When PAI-1 and PAI-2 were added during the POECs culture, the PA were observed significant low activity (p<0.05). The PA activity and protein expression were decreased by PA inhibitor. This results suggest that PAI-1 and PAI-2 have a suppressive action on change of PA activity during the estrous cycle of pigs. Specifically, this study using PA inhibitor was effect the PA activity and PAI expression in oviduct epithelial cells in pigs.

Evaluation of Engineering Properties in Early-Age Concrete with TDFA (TDFA를 혼입한 초기재령 콘크리트의 공학적 특성 평가)

  • Park, Jae-Sung;Park, Sang-Min;Kim, Hyeok-Jung;Kwon, Seung-Jun
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.20 no.5
    • /
    • pp.1-8
    • /
    • 2016
  • This paper presents an evaluation of engineering properties in TDFA(Tire Derived Fuel Ash)- based concrete in early age. Concrete containing 0.5 of w/b(water to binder) ratio and 20% of FA(Fly Ash) replacement ratio are prepared, and FA content are replaced with TDFA from 3% to 12% for evaluating the effect of TDFA on fresh and hardened concrete properties. With higher than 6% of TDFA replacement ratio, workability is significantly worsened but it is improved with more SP(Super plasticizer) and AE(Air Entrainer) agent. Concrete with 6~12% of TDFA shows reasonable strength development and better resistance to carbonation and chloride attack in spite of early-aged condition. However concrete with 6% TDFA shows poor resistance to freezing and thawing action due to insufficient air content. If air content and workability are obtained, replacement of TDFA to 12% can be used for concrete with FA.

Design and Implementation of Fuzzy Agent Based On the Early Warning Method (조기경고기법에 기반한 퍼지 에이전트 설계 및 구현)

  • Lee, Hyeong-Il;Choi, Hak-Yun
    • Journal of the Korea Society of Computer and Information
    • /
    • v.16 no.6
    • /
    • pp.31-39
    • /
    • 2011
  • In order to maintain clean environment in an interior space and an enclosed cattle pen, we have to measure and control environmental factors which are temperature, humidity and CO2, CH4 and so on. Although the measured values are within the normal range, those are increased or decreased sharply by the feces or environmental impacts. In order to take early an appropriate action, we propose an early warning method(EWarM) in this paper, which can recognize the rapidly changing time for the increasing or decreasing rate of the measured values. In addition, we developed fuzzy control system based on an EWarM. We verified that this system based on an EWarM is used for eliminating that impacts through performance evaluation in a variety of environmental situations.

Physiological studies on cell division by the technique of synchronous culture of chlorella (I) (클로렐라의 동조배양법에 의한 세포분열의 생리학적 연구 1)

  • 이영녹;이종삼
    • Korean Journal of Microbiology
    • /
    • v.7 no.1
    • /
    • pp.1-9
    • /
    • 1969
  • Changes in the phosphorylation of Chlorella cells during the life cycle the aulotrophic and micotrophic synchronous culture were followed under the light and dark. 1. In the autotrophic culture of Chlorella the amounts of esterified phosphate compounds of the algal cell under the light increased during the growing period and decreased strikingly in the ripening period showing a peak at the $L_1$ i/-cell stage. 2. TRhe amount of total esterified phosphate compounds of the cell under the dark, however, decreased during the growing period and then kept fairly constnat during the ripening nad division periods showing the greates activity of the oxidative phosphorylation in the early growing stage. 3. It is presumed that the energy requirement of the dividing algal cell in the autotrophic culture is fulfilled prior to the nuclear division mostly by the photosynthetic phosphorylation. 4. In the mixotrophic culture, the amount of esterified phosphate compounds of the algal cells under the light increased during the growing period and decreased during the late ripening and early division periods showing a peak in the $L_2$-cell stage as in the case of the phosphorylation under the dark. 5. The phosphorylation of the fell grown in the glucose medium is more active under the dark than under the light in the stages of the growing and early ripening periods. 6. It is considered that the excess glucose in the algal cell not only promotes the oxidative phosphorylation but also inhibits the photosynthetic phosphorylation of the cell. 7. It is presumed that the energy requirement of the dividing algal cell in the glucose medium is fulfilled prior to the nuclear division by the combined action of oxidative and photosynthetic phosphorylation, mostly by the oxidative phosphorylation.

  • PDF

Research on Variables Related with Early Childhood Education Freshmen' Academic Interest - The Relationship Among Academic Self-Efficacy, Character Strengths and Learning Motivation - (전문대학 유아교육과 신입생의 학업흥미 관련 변인 탐색 - 학업적 자기효능감, 성격강점, 학업동기 간의 관계 -)

  • Park, Eun-Ju
    • Journal of Korea Entertainment Industry Association
    • /
    • v.13 no.1
    • /
    • pp.185-197
    • /
    • 2019
  • This study intended to analyze the early childhood education freshmen's academic interest. For this study relationship among academic self-efficacy, character strength and learning motivation. The study subjects were 144 early childhood education freshmen at K-college in Deagu. They answered the survey regarding academic self-efficacy scale, VIA-IS(Values in action inventory of strength) short form scale, school learning motivation scale. The collected data were analyzed by frequency analysis, descriptive statistics, pearson correlation and multiple regression analysis using SPSS 18.0 program. The study finding are as follows. First, the average of academic self-efficacy, character strength and learning motivation of students were near at the intermediate-level. Second, academic self-efficacy, character strength and learning motivation were significantly positive correlated. Third, when examining the relative effect of early childhood education freshmen's academic self-efficacy and character strength on learning motivation, self regulatory efficacy among the sub-factors for academic self-efficacy and courage among the sub-factors for character strengths.

The Effect of the Cultural Competence in Multicultural Nursing Education by Action Learning (액션러닝 기반의 다문화 간호교육이 문화적 역량 증진에 미치는 효과)

  • Kim, Yeon-Soon;Kim, Jin-Young
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.15 no.11
    • /
    • pp.6527-6535
    • /
    • 2014
  • This research aims is to confirm the effects of cultural competence of an action learning based teaching method in multicultural nursing education. Cultural competence was composed of cultural knowledge, cultural awareness and cultural acceptance. A total of 118 college students were enrolled in this study. Both before and after learning, the students were guided to fill out a questionnaire regarding culture competence. The students from each group studied multicultural nursing by different teaching types: the Traditional Lecture-based Teaching method (TLT) and Action Learning based Teaching method (ALT). Data analysis was carried out by SPSS 21.0. A pre-post comparison within the group was performed using a paired t-test and the comparison between groups was performed using ANCOVA. The results showed that there was a significant difference in the culture competence in both teaching methods. In addition, ALT showed higher cultural acceptance results than TLT; however, there was no difference in cultural knowledge and cultural awareness between the two groups Therefore, ALT should be considered as a teaching method to enhance cultural competence in multicultural nursing education for Nursing students. Further studies on instructional design according to the task types, nursing performance, and the validity of ALT will be needed.

An Empirical Approach for Gamer's Cognitive Model on Game Playing Experience : Towards Difference of Gamers' Expertise in World Warcraft Game (게임플레이 경험에 대한 게이머의 인지적 모형에 관한 실증적 접근 : World of Warcraft 게임에서 게이머의 전문성 차이를 중심으로)

  • Song, Seung-Keun
    • Journal of Korea Game Society
    • /
    • v.9 no.3
    • /
    • pp.23-33
    • /
    • 2009
  • This study aims to uncover the gamers' cognitive process during the gameplay and explore the differences between groups in the gamers' playing behavior according to their expertise: experts, intermediate players, and novices. To this end, the empirical experiment was conducted in 'World of Warcraft' game which is a good representative of MMO(Massively Multi-player Online) game currently. Verbal protocol and action protocol collected from the empirical experiment were analyzed according to the gamers' expertise. As a result of this study, we found that the different behavior patterns result from standardizing pattern of their actions for experts and forming the learning curves and the specific patterns of action for intermediate game players and novices. While three functional-actions as a collection action concentrates on the early stage of the game for experts, the novices' behavior pattern dispersedly appeared in all seven functional-action, such as search, combat, three type collections, avoid, and communication in the whole gameplay. This study represents the consistency and the difference derived from the comparison analysis between groups according to the expertise. This study is concluded with key implications to support game design guidelines according to experts, intermediate players, and novices. Consequently, the result of this study provides the basic to the development of MMO content for game novices.

  • PDF

Development of pushing force measuring system for coke oven machines using telemetry method (비 접촉원격 토오크 측정 시스템 개발)

  • 전종학;허윤기;최일섭
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 1997.10a
    • /
    • pp.1778-1781
    • /
    • 1997
  • The coke oven plant on a steel works has not, in the past, been regarded as a prime user of modern instrument technology. The reason for this perception may be due to the fact that the basic design of the coke battery has been changed little over the years. The recording and analysis of oven pushing force on a routine basis is seen as a means of monitoring plant operation. A torque sensor is set up at the shaft of the rotor for measuring pushing force. Pushing force data which is communicated form torque sensor to staor by telemetry method are shown on MMI(Man-Machine Interface) screen and stored in the database automatically. Perhaps the most important feature is that is allows a problem oven to be identified at an early stage and for corrective action to be taken before it develops into a refusal to push. In this way the mechanical loads imposed on the battery structlure can be held to a necessary minimum, so helping to prolong its service life.

  • PDF

Reinforcement learning Speedup method using Q-value Initialization (Q-value Initialization을 이용한 Reinforcement Learning Speedup Method)

  • 최정환
    • Proceedings of the IEEK Conference
    • /
    • 2001.06c
    • /
    • pp.13-16
    • /
    • 2001
  • In reinforcement teaming, Q-learning converges quite slowly to a good policy. Its because searching for the goal state takes very long time in a large stochastic domain. So I propose the speedup method using the Q-value initialization for model-free reinforcement learning. In the speedup method, it learns a naive model of a domain and makes boundaries around the goal state. By using these boundaries, it assigns the initial Q-values to the state-action pairs and does Q-learning with the initial Q-values. The initial Q-values guide the agent to the goal state in the early states of learning, so that Q-teaming updates Q-values efficiently. Therefore it saves exploration time to search for the goal state and has better performance than Q-learning. 1 present Speedup Q-learning algorithm to implement the speedup method. This algorithm is evaluated. in a grid-world domain and compared to Q-teaming.

  • PDF

Current Status of Knowledge, Attitude and Practice (KAP) and Screening for Cervical Cancer in Countries at Different Levels of Development

  • Raychaudhuri, Sreejata;Mandal, Sukanta
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.9
    • /
    • pp.4221-4227
    • /
    • 2012
  • Cancer of the uterine cervix is a worldwide menace taking innumerable womens' lives. The literature is vast and a large number of studies have been conducted in this field. Analyses have shown significant differences exist in terms of screening and HPV testing facilities among high income and low to middle income countries. In addition, acute lack of awareness and knowledge among the concerned population is particularly noted in rural areas of the low income countries. A detailed review of Indian case studies revealed that early age of marriage and childbirth, multiparity, poor personal hygiene and low socio-economic status among others are the principal risk factors for this disease. This review concludes that a two pronged strategy involving strong government and NGO action is necessary to minimize the occurrence of cervical cancer especially in low and medium income countries.