• Korean Institute of Interior Design Journal
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• v.19 no.3
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• pp.13-21
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• 2010

Early mosque architecture is time that islam attempts fixing since hjira by Muhammad. Before Umayyad dynasty is established a country since islam occurrence, islamic influence was not extended much and stayed in Mecca area. Of course, when is Patriarchal Caliphate period, although there was part territorial expansion, was in existing islam influence still. Regular territorial expansion to Umayyad dynasty several influences and religious conflict happen. Change about islamic architecture occurred much fatally. Therefore, can find islamic archetype about islamic architecture until Prophet Muhammad period and Patriarchal Caliphate period. Also, Muhammad that is Islamic originator participated to mosque architecture directly in life. Can understand philosophy about islamic architecture that Muhammad seeks in mosque architecture. Was age that seek Muhammad's philosophy department religious succession strongly to Patriarchal Caliphate period. Therefore, can understand role of religion, mosque architecture's meaning and role that seek in Islam. It was just before that early mosque architecture receives effect of conquest area or the surrounding country. Therefore, characteristic of mosque received much effect of Prophet Muhammad and qur'an. Do construction according to qur'an's notice based on Prophet's house's function to early mosque. qur'an is no direct delineation as form or architecture element. qur'an refers thing about spiritual aspect or function about special quality of mosque, role etc..

• YAKHAK HOEJI
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• v.55 no.1
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• pp.22-31
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• 2011

This systematic review was conducted to assess the clinical effect of ocular fluoroquinolones used for the treatment of bacterial conjunctivitis. A literature search for randomized controlled clinical trials registered up to January 2010 based on PubMed database, using the following search terms: conjunctivitis and fluoroquinolones (besifloxacin, moxifloxacin, gatifloxacin, levofloxacin, lomefloxacin, ciprofloxacin and ofloxacin) were performed. Pooled data on the clinical resolution and bacterial eradication rates derived from selected 16 studies were reported as the relative risk (RR) and 95% confidence interval (95% CI) compared with placebo. Early clinical resolution and microbiological eradication rates in placebo were 28% and 62% respectively. Fluoroquinolones were significantly effective comparing to placebo: early RR 1.94 (95% CI 1.60~2.34) and late RR 1.30 (1.19~1.43) in clinical resolution rates, and early RR 1.75 (1.58~1.94) and late RR 1.28 (1.18~1.39) in microbiological eradication rates. Besifloxacin, ciprofloaxain and moxifloxacin in clinical resolution, and besifloxacin and levofloxacin in microbiological eradication showed higher RRs than pooled overall fluoroquinolones' RRs. New quinolones had higher antibacterial potencies for all pathogens isolated from bacterial conjunctivitis and resistant isolates than old generation quinolones. In conclusion, ocular 7 fluoroquinolones were all effective than placebo for bacterial conjunctivitis and there were differences between quinolones in early and late clinical resolutions and microbiological eradications, and no differences in safety comparing to placebo.

• PNF and Movement
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• v.12 no.3
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• pp.159-165
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• 2014

Purpose: The purpose of this study was to investigate the effect of early ankle exercise with functional electrical stimulation(FES) on spasticity, strength and active range of motion of ankle in patients with stroke. Methods: This study included 21 patients with stroke, who were performed early ankle exercise combined FES. The exercise program comprised 5 sessions of 30 minutes per week for 4 weeks. The spasticity, strength and active range of motion of ankle were evaluated before and after training. The spasticity was measured by modified ashworth scale(MAS), strength of ankle was measured by hand-held dynamometer and active range of motion of ankle dorsi-flexion was measured by goniometer. All data were analyzed using SPSS 18.0. Results: Significant differences were observed the subjects for strength of ankle and active range of motion. The results of the study were as follow: strength of ankle was significantly increased subjects(p<.001) and active range of motion was significantly increased subjects(p<.001). Conclusion: Ankle is very important part of body in stroke patients. early ankle exercise with FES is effective for improvement of strength of ankle and active range of motion in patients with stroke. ealry ankle exercise with FES about stroke patient is very useful and effective. It is effective in clinical practice.

• Journal of Veterinary Clinics
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• v.25 no.2
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• pp.85-89
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• 2008

This study assessed the incidence of embryo and fetal loss following early pregnancy diagnosis using ultrasonography in dairy cows. A positive pregnancy was a recognition of the vesicle, embryo or fetus by ultrasonography. Seven hundreds and two pregnancies determined by ultrasonography following artificial insemination were divided into three groups according to the number of days diagnosed pregnant: early A group (27 to 40 days, n = 143), early B group (41 to 50 days, n = 172), or standard group (51 to 70 days, n = 387). Following a positive pregnancy diagnosis, embryo or fetal loss included all cows with observed abortions and cows found open after the positive pregnancy diagnosis. The incidence rate of embryo or fetal loss within 7 days after pregnancy diagnosis was 1.4, 0.6 and 0.3% for the early A, early B, and standard groups, respectively (P>0.05). The incidence of the embryo or fetal loss during 8 to 30 days after pregnancy diagnosis did not differ (P>0.05) among the early A (0%), early B (1.2%), and standard groups (1.0%). Furthermore, the cumulative incidence of the embryo or fetal loss before calving did not differ (P>0.05) among the early A (9.8%), early B (9.3%), and standard groups (5.9%). These results indicate that early pregnancy diagnosis using ultrasonography does not increase the risk of embryo and fetal loss compared with that of routine pregnancy diagnosis in dairy cows.

• Journal of Nutrition and Health
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• v.18 no.4
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• pp.318-327
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• 1985

This study was designed to investigate the effect of early protein undernutrition of rats on later susceptibility to lead poisoning. Weanling rats, weighing about 55 grams, were malnourished by feeding low protein diets ( 12% and 5% casein diet ) during the four weeks of protein deprivation period. For the following 5 weeks, the malnourished rats were fed with 25% casein diet as rehabilitation diet. After the rehabilitation period, all rats were fed with 25% casein diet and the drinking water containing 2000ppm-Pb during the four weeks. The results obtained were as follows ; 1 ) Feed intake, body weight gain and food efficiency ratio were reduced in all rats exposed to lead, especially in rats fed with 5% casein diet during the four weeks of weanling period. 2 ) Enlargement of kidney and spleen were observed in all rats exposed to lead and were more remarkable in rats fed with 5% casein diet. 3 ) In rats exposed to lead, activity of serum glutamic oxaloacetic transaminase ( S- GOT ) was significantly increased by increasing the degree of early protein deprivation, whereas hematocrit value was significantly decreased. Activity of serum glutamic pyruvic transaminase ( S- GPT ) was shown a tendency to increase by increasing the degree of early protein deprivation, but the difference was not significant. 4) In rats exposed to lead, the amount of lead accumulation in kidney was increased by increasing the degree of early protein deprivation. The significant increase was shown in rats fed with 5% casein diet during the four weeks of weanling period. The results of the experiment suggest that early protein undernutrition, even after some period of rehabilitation, may enhance the later susceptibility to lead poisoning.

• Journal of Korean Neurosurgical Society
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• v.58 no.1
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• pp.14-21
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• 2015

Objective : To study the effect of early intervention and rehabilitation in the expression of aquaporin-4 and ultrastructure changes on cerebral palsy pups model induced by intrauterine infection. Methods : 20 pregnant Wistar rats were consecutively injected with lipopolysaccharide intraperitoneally. 60 Pups born from lipopolysaccharide group were randomly divided into intervention group (n=30) and non-intervention group (n=30); intervention group further divided into early intervention and rehabilitation group (n=10), acupuncture group (n=10) and consolidate group (n=10). Another 5 pregnant rats were injected with normal saline intraperitoneally; 30 pups born from the normal saline group were taken as control group. The intervention group received early intervention, rehabilitation and acupuncture treatment. The motor functions of all pups were assessed via suspension test and modified BBB locomotor score. Aquaporin-4 expression in brain tissue was studied through immunohistochemical and western-blot analysis. Ultrastructure changes in damaged brain and control group were studied electron-microscopically. Results : The scores of suspension test and modified BBB locomotor test were significantly higher in the control group than the intervention and non intervention group (p<0.01); higher in the intervention group than the non-intervention group (p<0.01). The expression of Aquaporin-4 was lower in intervention and non intervention group than in the control group (p<0.01); also lower in non-intervention group than the intervention group (p<0.01). Marked changes were observed in ultrastructure of cortex and hippocampus CAI in brain damaged group. Conclusion : Early intervention and rehabilitation training can improve the motor function in offspring with brain injury and reduce the expression of aquaporin-4 in damaged brain.

• Magazine of the Korean Society of Agricultural Engineers
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• v.14 no.3
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• pp.2677-2684
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• 1972

This study was carried out to search for an effect on strengths of a pozzolan and a high-early strength cements due to accelerating the initial setting and a rate of strength development at early age, and to obtain the effects applicable for structural construction works safety in the cold winter weather. The results of the study were as follows: 1. The early strength of high-early strength cement was higher than an ordinary portland cement(Type I). 2. High-early strength cement had a characteristic suitable for construction works in the cold weather due to the rate of acceleration of the eary strength. 3. When using pozzolan cements, a weight proportion should be considered in mix design since the pozzolan cement has a lower specific gravity than other portland cements. 4. It was desirable for the pozzolan cement to shorten the storage period since particles of the pozzolan cement was so fine that it was likely to weathering.

• Human Ecology Research
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• v.52 no.5
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• pp.483-494
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• 2014

The purpose of this study was to investigate the causal relationship of early adolescents' personal variables and social support on their self-esteem by grade. Information on 226 6th graders from elementary schools and 226 1st year students from middle schools in Busan was collected. Early adolescents' prosocial behavior, academic achievement, social support, and self-esteem were assessed using their self-reports. For the data analysis, Cronbach's ${\alpha}$, t -test, Pearson's correlation coefficient, and multiple regression were used. The collected data were analyzed by the SPSS ver. 21.0 program for Windows. The major findings were as follows: first, early adolescents' prosocial behavior, academic achievement, social support demonstrated a significant difference between grades. Second, peers' social support was the most powerful determinant of self-esteem in both the 6th graders from elementary schools and the 1st year middle school students. Third, prosocial behavior had the greatest total effect on self-esteem in the case of both groups of students. The middle schoolers' academic achievement had no causal effect on their self-esteem. The findings from this study indicate that early adolescents' personal variables and social support are important elements that affect their self-esteem differently depending on their grade. Further, the findings of this study can be used as fundamental data to develop a teaching plan and provide counseling for early adolescents in order to increase their self-esteem.

• Development and Reproduction
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• v.21 no.2
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• pp.205-213
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• 2017

The aim of this study was to determine the effect of additional alpha-linolenic acid (ALA) supplementation during in vitro maturation (IVM) and culture (IVC) on nucleic maturation and embryo development of pigs. Cumulus-oocyte complexes (COCs) were incubated in IVM medium containing different concentration of ALA (25, 50 and $100{\mu}M$) for 44 h. After in vitro maturation, nuclear maturation of oocytes were evaluated by aceto-orcein stain. Mature oocytes with $50{\mu}M$ ALA were fertilized and cultured in IVC medium with ALA (25, 50 and $100{\mu}M$) during early-embryogenesis (48 hours after fertilization). Then, embryos were cultured with $25{\mu}M$ ALA during early embryogenesis and/or late embryogenesis (120 hours after early-embryogenesis). In results, oocyte maturation were significantly increased by $50{\mu}M$ ALA treatment groups compared with control groups (p<0.05). Treatment of $25{\mu}M$ ALA during early-embryogenesis enhanced cleavage rate of embryo compared with other groups (p<0.05), whereas formation and total cell number of blastocyst had no significant difference. Similarly, cleavage rate of embryos were increased by $25{\mu}M$ ALA supplement during early- or late-embryogenesis than ALA treatment both stage of embryogenesis (p<0.05), but did not influence to blastocyst formation. Interestingly, total cell number of blastocyst were enhanced in ALA treatment group during early-embryogenesis. These findings indicated that ALA supplement enhance the nuclear maturation of oocyte and embryo development, however, excessive ALA could negatively influence. Therefore, we suggest that ALA is used for improvement of in vitro production of mammalian embryo and further study regarding with functional mechanism of ALA is needed.

• Tuberculosis and Respiratory Diseases
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• v.83 no.2
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• pp.167-174
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• 2020

Background: The purpose of this study was to investigate the effect of early tracheostomy on clinical outcomes in patients requiring prolonged acute mechanical ventilation (≥96 hours). Methods: Data from 575 patients (69.4% male; median age, 68 years), hospitalized in the medical intensive care unit (ICU) of a university-affiliated tertiary care hospital March 2008-February 2017, were retrospectively evaluated. Early and late tracheostomy were designated as 2-10 days and >10 days after translaryngeal intubation, respectively. Results: The 90-day cumulative mortality rate was 47.5% (n=273) and 258 patients (44.9%) underwent tracheostomy. In comparison with the late group (n=115), the early group (n=125) had lower 90-day mortality (31.2% vs. 47.8%, p=0.012), shorter stays in hospital and ICU, shorter ventilator length of stay (median, 43 vs. 54; 24 vs. 33; 23 vs. 28 days; all p<0.001), and a higher rate of transfer to secondary care hospitals with post-intensive care settings (67.2% vs. 43.5% p<0.001). Also, the total medical costs of the early group were lower during hospital stays than those of the late group (26,609 vs. 36,973 USD, p<0.001). Conclusion: Early tracheostomy was associated with lower 90-day mortality, shorter ventilator length of stay and shorter lengths of stays in hospital and ICU, as well as lower hospital costs than late tracheostomy.