• Toxicological Research
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• v.13 no.3
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• pp.215-222
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• 1997

The features of seizure-related brain injuries in rats poisoned i.p. with diisopropylfiuorophosphate were investigated. Pyridostigmine bromide (0.1 mg/kg) and atropine methylnitrate (20 mg/kg), which are centrally inactive, were pretreated i.m. 30 min and 10 min, respectively. before diisopropylfluorophosphate (10 mg /kg, $2LD_50$) poisoning to reduce the mortality and eliminate peripheral signs. Diisopropylfluorophosphate induced severe limbic seizures, and early necrotic and delayed apoptotic brain injuries. The necrotic brain injury, which was closely related to seizure intensity, was exerted as early as 1 hr predominently in hippocampus and piriform cortex. showing spongiform change (malacia) of neurophils in severe cases, in contrast to a typical apoptotic (TUNEL-positive)pattern after 12 hr in thalamus, and a mixed type in amygdala. Nitric oxide content in cerebrospinal fiuid significantly increased after 2 hr, reaching a maximal level at 6 hr. Pretreatment with $_L-N^G$-nitroarginine, an inhibitor of nitric oxide synthase, reduced nitric oxide content and attenuated only apoptotic brain injury in all four brain regions examined without affecting seizure intensity and necrotic injury. Taken together, early necrotic and delayed apoptotic brain injuries induced by diisopropylfiuorophosphate poisoning in rats may be related to seizure intensity and nitric oxide production, respectively.

• Korean Journal of Child Studies
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• v.21 no.1
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• pp.283-294
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• 2000

The purpose of this study was to determine early childhood education(ECE) and early childhood special education(ECSE) teachers' perceptions of (a)important teacher competencies needed for working in inclusive early childhood programs and (b)current levels of these competencies. Sixty-two ECE teachers and 77 ECSE teachers responded to the survey developed for this study. There were no differences between the ECE teachers and ECSE teachers in the ratings of importance of the competency domains. However, the ECSE teachers had significantly higher perceptions than the ECE teachers of their self-proficiency on competencies related to child development, curriculum and instruction, assessment procedures, working with other adults, and professionalism. Both the ECE and ECSE teachers perceived the greatest need for further training in competencies related to assessment procedures and working with families and other adults.

• Journal of Environmental Impact Assessment
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• v.20 no.3
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• pp.269-279
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• 2011

Sustainability assessments tend to integrate ecological, social, and economic concerns. Sustainability assessment could be considered the highest rung in the assessment ladder. Broad strategies that seek to integrate individual SEA(Strategic Environmental Assessment) could be subjected to a sustainability assessment. Sustainability assessment could incorporate global and transboundary effects and priorities into SEA and project-level EIA(Environmental Impact Assessment). SEA could provide an environmental context and direction for project-level EIA. Procedural and substantive EIA requirements can be addressed through tiering such as sustainability assessment, SEA, project-level EIA. In Korea, PERS(Prior Environmental Review System) that has been utilized to evaluate administrative plans related with various kinds of development projects should be evolved not only to incorporate environmental impacts into early stage decision-making, but also to implicate sustainability assessments that include social equity and economic efficiency. Integration of SEA and sustainability assessment can be initiated through the application of DPSIR (Driving Force - Pressure - State - Impact - Response ) framework that was developed by European Environmental Agency.

• Korean Journal of Adult Nursing
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• v.25 no.2
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• pp.113-124
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• 2013

Purpose: Purposes of this study were to develop a reliable and valid checklist to assess and manage post-stroke dysphagia and to identify its utilization. Methods: The first step was to develop checklist through systematic literatures reviews, to test the content validity from 11 clinical experts, and to test the construct validity and the internal consistency from 97 patients with post-stroke dysphagia. The second step was to identify clinical use of the checklist from the same 97 patients. Results: A total of 18 items compromised the assessment checklist and 64 items for intervention checklist. Internal consistencies of assessment checklist and intervention checklist were .84 and .98, respectively. In both checklists, level of utilization of general appearance was the highest, while that of early signs of aspiration was the lowest. The utilization levels of two checklists were significantly higher among patients who were less than 60 years old, and had liquid diet, facial paralysis, and previous history of aspiration pneumonia. Conclusion: We found that the checklists were reliable and valid. Further study is needed to develop specific strategies to improve nurses' use of assessment and intervention checklists for post-stroke dysphagia.

• Korean Journal of Computational Design and Engineering
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• v.16 no.2
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• pp.146-155
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• 2011

As the seriousness of environmental pollution being on a rise, a low carbon and environment-friendly design for energy efficiency has been issued. With respect to energy in the construction industry, an adoption of BIM which is possible for the various energy performance assessments in the early design phase has been actively working on. In the most cases of energy performance assessment, the data compatibility from the lack of standard software and format became a problem and the improvement for data compatibility system has been needed. This study is to develop the IFC based IDF converter as a middleware which connects between BIM software and energy analysis software. For the building energy performance assessment, Energy Plus and IFC are selected for the standard energy analysis software and its file format. Parameters are organized by steps and the integrated material library is built so it is trying to reduce the existing problem of energy software interface as much as possible. The development of IDF Converter will promote the spread of related fields with increasing the BIM standard and the utilization of energy performance assessment.

• Environmental Analysis Health and Toxicology
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• v.25 no.1
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• pp.19-26
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• 2010

Discharged materials from the point or non-point source are released into the sea, and as the results, marine environment is directly affected. We must estimate the impacts of contaminants to marine pollution rapidly and accurately. Therefore, it is needed on early warning system for appreciating marine environmental impacts, and required a bioassay to evaluate abnormal changes. A bioassay test was developed to examine the effects of heavy metal contaminants on the early life stages of the marine annimals. We have studied the effects of metals on early development of a sea urchin species, Strongylocentrotus intermedius. S. intermedius embryos were tested with six metals (Cu, Ag, Zn, Cd, Cr, Ni) and showed the highest sensitivity to Cu as well as the lowest sensitivity to Cd. The order of biological impact for metals was Cu>Ag>Ni>Zn>Cr>Cd. In accordance with the results, sea urchins embryos can provide biological criteria for seawater quality assessment. The sensitivity of developmental bioassay whith S. intermedius is at intermediate level among marine organisms commonly used in aquatic bioassays. And this sea urchin can be routinely employed as a test organism for ecotoxicity assays.

• Journal of the korean academy of Pediatric Dentistry
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• v.40 no.1
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• pp.72-81
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• 2013

Early childhood caries prevalence has increased significantly in children ages 2~5 years. ECC disproportionately affects lower socioeconomic and minority groups, is a predictor for future decay, but is preventable and manageable. Caries risk assessment systematically derives a patient's caries risk and is important during an infant oral health visit beginning at age 1. Information obtained through a risk assessment can guide a disease management care path tailored to an individual's age and risk to effectively treat and manage one's caries disease process.

• Korean Journal of Radiology
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• v.25 no.1
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• pp.86-102
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• 2024

Early diagnosis, accurate assessment, and localization of peritoneal metastasis (PM) are essential for the selection of appropriate treatments and surgical guidance. However, available imaging modalities (computed tomography [CT], conventional magnetic resonance imaging [MRI], and 18fluorodeoxyglucose positron emission tomography [PET]/CT) have limitations. The advent of new imaging techniques and novel molecular imaging agents have revealed molecular processes in the tumor microenvironment as an application for the early diagnosis and assessment of PM as well as real-time guided surgical resection, which has changed clinical management. In contrast to clinical imaging, which is purely qualitative and subjective for interpreting macroscopic structures, radiomics and artificial intelligence (AI) capitalize on high-dimensional numerical data from images that may reflect tumor pathophysiology. A predictive model can be used to predict the occurrence, recurrence, and prognosis of PM, thereby avoiding unnecessary exploratory surgeries. This review summarizes the role and status of different imaging techniques, especially new imaging strategies such as spectral photon-counting CT, fibroblast activation protein inhibitor (FAPI) PET/CT, near-infrared fluorescence imaging, and PET/MRI, for early diagnosis, assessment of surgical indications, and recurrence monitoring in patients with PM. The clinical applications, limitations, and solutions for fluorescence imaging, radiomics, and AI are also discussed.

• Korean Journal of Child Education & Care
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• v.18 no.1
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• pp.193-216
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• 2018

The purpose of this study was to analyze the mediating and moderating effect of directors' transformational leadership or transactional leadership between early childhood teachers' emotional labor and their burn out. The subjects were 211 early childhood teachers in the kindergartens and day care centers located in Kyonggido. 'Emotional Labor Assessment for Early Childhood Teachers', 'Assessment of Directors' Transformational Leadership or Transactional Leadership', and 'Early Childhood Teachers' Burn Out Assessment' were used in the collection of data. It used Pearson's correlation and Multi-Regression Analysis to analyze the data. The results of this study are as follows; first, there were positive correlations between early childhood teachers' emotional labor and their burn out. And, there was negative correlations between early childhood teachers' burn out and directors' transformational leadership or transactional leadership. Second, it was revealed that early childhood teachers' emotional labor was found as the positive predict variable for effecting their burn out. Third, it was revealed that directors transformational leadership or transactional leadership was found as the negative predict variable for effecting early childhood teachers' burn out. Fourth, directors' transformational leadership was a mediating effect of job environment dissatisfaction which is a sub area of burn out. In addition, directors' transactional leadership was a mediating effect of physical-emotional exhaustion which is a sub area of burn out.

• Korean Journal of Remote Sensing
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• v.37 no.3
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• pp.503-514
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• 2021

Rice production with adequate level of area is important for decision making of rice supply and demand policy. It is essential to grasp rice cultivation areas in advance for estimating rice production of the year. This study was carried out to classify paddy rice cultivation in Gimje-si using sentinel-1 SAR (synthetic aperture radar) and UAV imagery in early July. Time-series Sentinel-1A and 1B images acquired from early May to early July were processed to convert into sigma naught (dB) images using SNAP (SeNtinel application platform, Version 8.0) toolbox provided by European Space Agency. Farm map and parcel map, which are spatial data of vector polygon, were used to stratify paddy field population for classifying rice paddy cultivation. To distinguish paddy rice from other crops grown in the paddy fields, we used the decision tree method using threshold levels and random forest model. Random forest model, trained by mainly rice cultivation area and rice and soybean cultivation area in UAV image area, showed the best performance as overall accuracy 89.9%, Kappa coefficient 0.774. Through this, we were able to confirm the possibility of early estimation of rice cultivation area in Gimje-si using UAV image.