• 제목/요약/키워드: EX

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Extracellular RNAs and Extracellular Vesicles: Inception, Current Explorations, and Future Applications

  • Perumal, Ayyappasamy Sudalaiyadum;Chelliah, Ramachandran;Datta, Saptashwa;Krishna, Jayachandran;Samuel, Melvin S.;Ethiraj, Selvarajan;Park, Chae Rin
    • 한국식품위생안전성학회지
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    • 제35권6호
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    • pp.535-543
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    • 2020
  • 유전적 조절, 유전자 발현 그리고 환경적 단서, 화학적 신호에 대응하는 표현형 변이에서 세포 RNA는 ubiquitous 역할 이외에도 세포 외 RNA(exRNA)라 하는 새로운 형태의 RNA는 추후 연구의 방향을 제시한다. exRNA는 membrane vesicles 또는 세포 외 소포체(EV)로 알려진 membrane blebs를 통해 세포 외부로 운반된다. EV의 형성은 원핵생물, 진핵생물, 고세균을 포함한 모든 미생물군에 우세하게 보존되어있다. 본 리뷰는 세균 유래 exRNA에 관해 세가지 주제에 초점을 두었다. exRNA의 발견과 박테리아 유전자 배열에 대한 외부 RNA의 영향, b. exRNA의 분비기작을 통한 방출, c. 다른 그람음성 및 그람양성균에 의해 분비되는 exRNA로 고안될 수 있는 응용 가능분야이다. 본 리뷰에서 장내 미생물군의 probiotics 및 후성유전학적 규제에서 본 exRNA와 exRNA마커와 같은 EV파생 응용프로그램에 대한 의견을 제공할 것이다.

현대 주거건축에서 나타나는 탈정형적(脫定型的) 공간구성과 다의적(多義的) 표현 특성에 관한 연구 (A Study on Ex-formal Space Compositions and Polysemous Expressions Observed in Contemporary Residential Architecture)

  • 장훈익
    • 한국실내디자인학회논문집
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    • 제16권2호
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    • pp.163-171
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    • 2007
  • The present study approached the characteristics of various space compositions in contemporary residential architecture through the concept of ex-formality, and found that ex-formal spaces are composed through the variation of floor, wall, ceiling or roof and derived four types of ex-formal space composition - ex-cubic space composition using folding, plastic space composition using the plasticity of concrete, atypical space composition using geometric manipulation, and non linear space composition using digital technology. Based on this, additionally, we derived elements expressing the characteristics of ex-formal space composition, which are obliqueness, inclination, flexibility in ex-cubic space composition using folding, plasticity and fluidity in plastic space composition using the plasticity of concrete, ex-construction, dynamism and asymmetry in atypical space composition using geometric manipulation, and flexibility, fluidity, self similarity and plasticity in non linear space composition using digital technology. On the other hand, this study purposed to help understand various space expression patterns of contemporary residential architecture by analyzing how these types of ex-formal space composition and polysemous expression characteristics have been represented in contemporary residential architecture since the 1990s.

한국당귀(Angelicae gigantis Radix) 엑스가 흰쥐의 실험적 고지혈증에 미치는 영향 (Effect of Angelicae gigantis Radix Extract on Experimentally Induced Hyperlipemia in Rats)

  • 임종훈;오형수;정명현
    • 생약학회지
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    • 제29권4호
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    • pp.300-311
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    • 1998
  • This study was attempted to investigate the effects of "Angelicae gigantis Radix extract" (AG.EX.) on the activities of GOT and GPT, the contents of total lipid, triglyceride, total cholesterol, phospholipid and ${\beta}-lipoprotein$ in serum, and the weight change ratio of body, liver and spleen in the experimentally induced hyperlipemic rats by administering the extract of 300 and 500 mg/kg p.o.. Significant test was performed by comparision with the biochemical values between control group and experimentally hyperlipemic rats. In the activities of s-GOT and s-GPT inhibition effects were significantly appeared in all dose of AG.EX. (especially more excellent in ethanol extract) and Angelicae acutilobae Radix extract (AA.EX.) as compared with the control group. The content of total lipid was remarkably decreased in all sample group when compared with the control group, and AA.EX. showed more excellent decreasing effect than AG.EX. The contents of triglyceride and total cholesterol were significantly lowered in all sample group, and more significantly decreased in water extract of AG.EX. and ethanol extract of AA.EX. The content of phospholipid was significantly decreased in all sample group and AG.EX. was more significantly decreased than AA.EX. The increasing rate of body weight in all sample groups except AA.EX. 500 mg/kg was increased more than control group and more significantly remarkable in dose of 300 mg/kg than 500 mg/kg. The increasing rate of liver weight in all sample groups was increased more than control group, and AG.EX. was more increased than AA.EX.

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운동으로 유발된 산화 스트레스와 마늘의 항산화 작용 (Antioxidant Effect of Garlic Supplement against Exercise-Induced Oxidative Stress in Rats)

  • 윤군애
    • Journal of Nutrition and Health
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    • 제40권8호
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    • pp.701-707
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    • 2007
  • This study was to investigate lipid peroxidation, antioxidant enzyme activity and DNA damage after exercise, and the protective effect of garlic against exercise-induced oxidative stress. Male Sprague-Dawley rats(4 weeks old) were randomly divided into three groups of 6 rats each; control group(Con) without garlic and exercise, Ex group with exercise alone, and Ex-G group with 2% garlic and exercise. For 4 weeks, rats were given diets containing 15% corn oil and 1% cholesterol with or without garlic. The swimming was selected as a model for exercise performance. Rats swam for 40 min a day, for 5 days a week. Group Ex and Ex-G showed significant lowering in body weight gain and fat accumulation compared to control. No significant changes were observed in levels of plasma cholesterol and triglyceride among three groups, demonstrating that exercise and garlic had no effects on changes of blood lipid. This finding of blood lipid seems to be due to higher plant sterol content in corn oil. The DNA tail moment of lymphocytes showed greater tendency in Ex and Ex-G than in control, but garlic supplements failed to suppress DNA damages. Compared to control, Ex had higher plasma TBARS which was lowered to the control's level in Ex-G with 2% garlic supplementation(p<0.05). Ex-G led to a higher hepatic superoxide dismutase(SOD) activity than control and Ex(p<0.05). Activity of hepatic catalase was also increased in Ex-G, while in Ex it was significantly low(p<0.05). It seemed that TBARS levels were related to the activities of SOD and catalase, and that garlic contributed to increasing the enzyme activities and led to decrease of TBARS. These results demonstrate that lipid peroxidation and DNA damage occur as a consequences of oxidative stress after exercise, and that antioxidant defense against oxidative stress could be enhanced by garlic supplementation through the induction of antioxidant enzymes. However, further investigations should be done on the garlic effect on DNA damage.

하천 제방의 영상 점군에서 식생 점 제거 필터링 기법 비교 분석 (Comparative Analysis of Filtering Techniques for Vegetation Points Removal from Photogrammetric Point Clouds at the Stream Levee)

  • 박희성;이두한
    • Ecology and Resilient Infrastructure
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    • 제8권4호
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    • pp.233-244
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    • 2021
  • 본 연구에서는 식생이 무성한 제방의 이상유무 점검을 위한 지상 LiDAR(Light Detection And Ranging) 측량의 적용성을 검토하였다. 지상 LiDAR 측량으로 생성된 제방의 영상 점군 자료에 색상필터 및 형태필터를 적용하여 각 기법별 정확성과 특성을 평가하였다. 임진강 제방의 영상 점군 자료를 이용하여 CIVE, ExG, ExGR, ExR, MExG, NGRDI, VEG, VVI, ATIN, ISL 등의 10가 식생 제거 필터를 적용하였다. 결과에 의하면 정확성은 ISL, ATIN, ExR, NGRDI, ExGR, ExG, MExG, VVI, VEG, CIVE 등의 순서로 나타났다. 색상필터는 지반 구분에 한계를 보였으며 풀꽃을 지반으로 구분하기도 했다. 형태필터는 지반 구분 정확도가 우수하나 거석을 식생으로 인식하는 한계도 보였다. 전체적으로 형태필터가 우수하나 계산 시간에서 10 배 정도 소요되었다. 정확도와 속도 향상을 위해서 형태필터와 색상필터를 결합한 복합필터에 대한 연구가 필요하다.

이동통신 통화품질의 지표화 - OECD 국가들을 중심으로 - (Making an Index of Mobile Telecommunications Service Quality - An Application to OECD Countries -)

  • 강임호;김용규
    • 정보화정책
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    • 제18권2호
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    • pp.85-98
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    • 2011
  • 이 논문에서는 OECD 주요국의 이동통신사업자 통계자료를 이용하여 이동통신 통화품질을 지표화하고자 하였다. 먼저 각국의 이동통신 1위 사업자의 최근 5년간의 자본지출(CapEx) 합계를 통화품질을 나타내는 대리변수로 설정하였다. 이 CapEx를 피설명변수로 하고 인구, 면적, 3G 커버리지, 이동통신시장의 허핀달-허쉬만 지수(HHI), 사업자평균 EBITDA 마진율, 1위사업자의 매출액점유율을 설명변수로 하여 회귀분석을 수행하였다. 이 회귀분석에서 CapEx 중 인구와 면적에 의해 설명되지 않는 부분을 통화품질지표로 간주하였다. 이렇게 구한 각국의 통화품질지표를 비교한 결과, 한국과 일본의 통화품질이 프랑스, 영국, 독일에 비해 높을 것이라는 점을 유추할 수 있었다.

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아래아 한글 파일의 텍 파일로의 변환 소프트웨어 구현 (Implementation of Hangul to $T_EX$ conversion software)

  • 김성원;이한나;박상훈;오창혁
    • Journal of the Korean Data and Information Science Society
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    • 제21권1호
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    • pp.99-107
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    • 2010
  • 본 연구에서는 아래아 한글 형식으로 작성된 논문 파일을 $T_EX$ 형식의 파일로 변환하는 소프트웨어를 구현하였다. 아래아 한글은 문서작성 또는 출판의 도구로써 사용되는 국내에서 많은 사용자를 가진 워드프로세서이며, 이를 이용한 수식이 포함된 논문 원고의 편집은 상대적으로 수월한 것으로 알려져 있다. $T_EX$은 일반 텍스트 편집기로 작성된 문서를 컴파일하여 고품질의 문서를 얻는 수식 전문조판 프로그래밍 언어이다. 구현된 소프트웨어는 정해진 작성 형식에 따라 아래아 한글로 작성된 논문 원고의 본문, 표, 문단 형식, 수식, 특수문자 등을 지정된 스타일 파일에 맞춘 $T_EX$ 형식으로 변환 한다. 구현의 예제로써 한국데이터정보과학회지 (JKDISS)의 아래아 한글 논문 형식과 $T_EX$ 스타일 파일을 사용하였다.

Analysis of fluctuations in ex-core neutron detector signal in Krško NPP during an earthquake

  • Tanja Goricanec;Andrej Kavcic;Marjan Kromar;Luka Snoj
    • Nuclear Engineering and Technology
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    • 제56권2호
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    • pp.575-600
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    • 2024
  • During an earthquake on December 29th 2020, the Krško NPP automatically shutdown due to the trigger of the negative neutron flux rate signal on the power range nuclear instrumentation. From the time course of the detector signal, it can be concluded that the fluctuation in the detector signal may have been caused by the mechanical movement of the ex-core neutron detectors or the pressure vessel components rather than the actual change in reactor power. The objective of the analysis was to evaluate the sensitivity of the neutron flux at the ex-core detector position, if the detector is moved in the radial or axial direction. In addition, the effect of the core barrel movement and core inside the baffle movement in the radial direction were analysed. The analysis is complemented by the calculation of the thermal and total neutron flux gradient in radial, axial and azimuthal directions. The Monte Carlo particle transport code MCNP was used to study the changes in the response of the ex-core detector for the above-mentioned scenarios. Power and intermediate-range detectors were analysed separately, because they are designed differently, positioned at different locations, and have different response characteristics. It was found that the movement of the power range ex-core detector has a negligible effect on the value of the thermal neutron flux in the active part of the detector. However, the radial movement of the intermediate-range detector by 5 cm results in 7%-8% change in the thermal neutron flux in the active part of the intermediate-range detector. The analysis continued with an evaluation of the effects of moving the entire core barrel on the ex-core detector response. It was estimated that the 2 mm core barrel radial oscillation results in ~4% deviation in the power and intermediate-range detector signal. The movement of the reactor core inside baffle can contribute ~6% deviation in the ex-core neutron detector signal. The analysis showed that the mechanical movement of ex-core neutron detectors cannot explain the fluctuations in the ex-core detector signal. However, combined core barrel and reactor core inside baffle oscillations could be a probable reason for the observed fluctuations in the ex-core detector signal during an earthquake.

$T_EX$과 타이포그래피에 관한 소고 (Short Introduction to $T_EX$ and Typography)

  • 조진환
    • 한국수학교육학회지시리즈E:수학교육논문집
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    • 제19권4호
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    • pp.823-837
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    • 2005
  • [ $T_EX$ ] is a typesetting system created by Donald E. Knuth for producing publication-quality scientific books and journals. It is famous for the line breaking algorithm, the formatting of complex mathematical formula, and the powerful macro programming capability. Recently $T_EX$ plays a new role of an automatic typesetting engine. The paper describes $T_EX$ in the framework of typography by comparing with DTP softwares and word processors.

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