• 대한한방내과학회지
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• 제39권2호
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• pp.147-153
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• 2018

Objective: The purpose of this case report is to evaluate the effect of electroacupuncture on Pal-sa (EX-UE9) for unilateral motor disturbance of the hand after cerebral infarction. Methods: One patient with unilateral motor disturbance of the hand following cerebral infarction (right basal ganglion and corona radiata) was treated with acupuncture, herbal medication, and electroacupuncture on Pal-sa (EX-UE9) once daily from June 30, 2016 to July 4, 2016. We evaluated improvement using the Box and Block Test (BTT) and 10-seconds Test, including the Finger Individual Movement Test (FIMT), the Hand Pronation and Supination Test (HPST), and the Finger Tapping Test (FTT). Results: After five days of treatment, increase of FIMT and FTT scores was observed after electroacupuncture on Pal-sa (EX-UE9). However, no increase was observed in BBT or HPST scores. Conclusions: This study suggests that electroacupuncture on Pal-sa (EX-UE9) can help treat motor disturbance of the hand after cerebral infarction.

• 대한치과보철학회지
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• 제33권4호
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• pp.662-684
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• 1995

The purpose of this study was to evaluate the shear bond strength between various resin-bonded retainers and enamel according to the adhesive resins and retention types and observe the bond filure modes with scanning electron microscope(SEM). For this purpose, the followin eight sub-groups were tested in shear bond strength : 1) electrochemically etched group(Verabond) using Panavia EX and Superbond C&B 2) tin-plated group(PG-S) using Panavia EX and Superbond C&B 3) salt-treated group(Verabond) using Panavia EX and Superbond C&B 4) meshtreated group(Verabond) using Panavia EX and Superbond C&B. Thermocycling test was conducted on the condition of 15 second dwell time each in $5^{\circ}C$ and $55^{\circ}C$bath. Shear bond strength was measured by Instron Universal Testing Machine(medel 1125). The obtained results were as follows : 1. After thermocycling, the shear bond strengths of tin-plated group and electrochemically etched group were significantly greater than those of salt-treated group and mesh-treated group. And the shear bond strength of Panavia EX was greater than that of Superbond C&B with salt-treated group and tin-plated group(p<0.05). 2. Before thermocycling, electrochemically etched group using Superbond C&B produced the greatest shear bond strength(p<0.01). 3. The shear bond strength of electrochemically etched group using Superbond C&B was significantly decreased after thermocycling(p<0.01). 4. In observation of bond failure modes before thermocycling, Panavia EX highly exhibited enamel fracture. Tin-plated group using Superbond C&B adhesive failure between metal and resin and electrochemically etched group using Superbond C&B exhibited adhesive failure between enamel and rdsin. 5. In observation of failure modes after thermocycling, Panavia EX exhibited cohesive failure and Superbond C&B exhibited adhesive failure between resin and metal.

• Nutrition Research and Practice
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• 제11권2호
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• pp.97-104
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• 2017

BACKGROUND/OBJECTIVE: Although Angelica keiskei (AK) has widely been utilized for the purpose of general health improvement among Asian, its functionality and mechanism of action. The aim of this study was to determine the protective effect of ethanol extract of AK (AK-Ex) on acute hepatotoxicity induced by acetaminophen (AAP) in HepG2 human hepatocellular liver carcinoma cells and HepaRG human hepatic progenitor cells. MATERIALS/METHODS: AK-Ex was prepared HepG2 and HepaRG cells were cultured with various concentrations and 30 mM AAP. The protective effects of AK-Ex against AAP-induced hepatotoxicity in HepG2 and HepaRG cells were evaluated using 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide, lactate dehydrogenase (LDH) assay, flow cytometry, and Western blotting. RESULTS: AK-Ex, when administered prior to AAP, increased cell growth and decreased leakage of LDH in a dose-dependent manner in HepG2 and HepaRG cells against AAP-induced hepatotoxicity. AK-Ex increased the level of Bcl-2 and decreased the levels of Bax, Bok and Bik decreased the permeability of the mitochondrial membrane in HepG2 cells intoxicated with AAP. AK-Ex decreased the cleavage of poly (ADP-ribose) polymerase (PARP) and the activation of caspase-9, -7, and -3. CONCLUSIONS: These results demonstrate that AK-Ex downregulates apoptosis via intrinsic and extrinsic pathways against AAP-induced hepatotoxicity. We suggest that AK could be a useful preventive agent against AAP-induced apoptosis in hepatocytes.

• Restorative Dentistry and Endodontics
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• 제10권1호
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• pp.31-42
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• 1984

The toxic effect of adhesive resins on the dog's pulp tissue was studied with 70 teeth from 5 dogs. The experimental materials were Clearfil, a mixture of Clearfil with calcium hydroxide powder, Panavia-EX, and a mixture of Panavia-EX with calcium hydroxide powder. As a control group, calcium hydroxide powder was used. Each material was placed on the pulpotomized tissue surface. After 3 days, 1, 2,4, and 6 weeks, the teeth and apical tissue were processed routinly and stained with hematoxylin and eosin. Pathological tissue changes due to the toxicity of adhesive resins were observed by light microscope, and the pH of Panavia-EX and the Bonding agent of Clearfil were measured. Following were the results; 1. In the group of calcium hydroxide powder, slight inflammatory change was observed in the pulpotomized surface and adjacent pulp tissue on 3 day. 1 week case showed incomplete dentin bridge. The remaining pulp tissue was normalized according to the days elapsed. 2. In the group of Clearfil, early inflammatory change revealed in the superificial portion of the remaining pulp tissue on 3 day. The inflammation spreaded over the total pulp tissue and partial necrosis was observed in 1 week and 2 week cases. Total necrosis of pulp tissue and moderate inflammatory change at the apical tissue was noticed in 4 week and 6 week cases. 3. In the group of Panavia-EX, moderate inflammatory change appeared in the superficial pulp tissue on 3 day, and severe inflammatory change over all pulp tissue found in 1 week case. Pulp necrosis was obvious in 2 week case. 4 week and 6 week cases were totally necrotized up to the periapical tissue. 4. In the groups of mixtures with calcium hydroxide powder, the pulp tissue destruction was retarded, compared with the groups of Clearfil and Panavia-EX. 5. Panavia-EX was more destructive than Clearfil. 6. The acidity of freshly mixed Bonding agent of Cleafil was pH 4.0, and that of Panavia-EX was pH 2.0.

• 한국의학물리학회지:의학물리
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• 제13권3호
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• pp.139-148
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• 2002

The measured attenuation correction with transmission (Tx) scans produced quantitatively accurate images. However, it was not clear for optimal emission (Ex) and Tx scan time in PET imaging. This study was to evaluate acceptable Ex and Tx scan time by simulating clinical situations using various phantoms. Cylindrical and NEMA phantom were used for $^{18}$ F-PET scan using 2D protocol in GE Advance PETTM scanner. Cylindrical phantom was filled with 136 MBq 18F, and five regions of interests (ROI) were drawn on 23 slices. NEMA phantom had three inserts containing water, air and polytetrafluoro-ethylene (PTFE). Outside of these inserts were filled with 309 MBq of $^{18}$ F, and total 12 ROIs were drawn on 23 slices. Scans were carried out according to five Ex scan times: 2, 5, 10, 15, and 30 min, and nine Tx scan times: 2, 3, 4, 5, 7, 10, 15, 20, and 30 min. Images were reconstructed using measured attenuation correction, and ROI analyses were performed for all images, and mean, standard deviation (SD), coefficient of variation and percent errors were calculated. For cylindrical phantom study, ROI mean and SD were decreased as Ex and Tx time increased. Coefficients of variation were kept constant, when Tx was greater than 10 min. The amount of error decreased for the increment of Ex time from 10 min to 15 min was almost the same to that from 15 min to 30 min. In NEMA phantom Tx 15 min showed the lowest er개r level when the percent errors for three inserts were summed for all of the Ex times. This study suggested that Ex 15 min and Tx 15 min were acceptable as optimal scan time for the scanning protocol and the dose of radiopharmaceuticals used in these phantom study.

• 한국자기학회지
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• 제27권1호
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• pp.30-34
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• 2017

본 연구에서는 교환 결합력을 갖는 강자성/반강자성(AF) 박막에서 단자구 모델을 사용하여 교환 바이어스($H_{ex}$)의 각도 의존성을 계산하였으며, NiFe/MnIr 박막에서 측정한 결과와 비교 분석하였다. AF층 두께가 임계 두께 이상에서($t_{AF}$ > $t_c$) 계산한 $H_{ex}$의 각도 의존성은 전형적인 일방 이방성 특성을 보였으나, $0.5t_c$ < $t_{AF}$ < $t_c$에서는 $90^{\circ}$ 근처의 특정한 각도에서 AF 스핀의 고정에 의한 독특한 $H_{ex}$의 각도 의존성을 보였다. NiFe/MnIr(20 nm) 박막에서 측정한 $H_{ex}$의 각도 의존성은 전형적인 일방 이방성 특성을 보였으나, NiFe/MnIr(4 nm) 박막에서는 일방 이방성 특성과 AF 스핀의 고정에 의한 특성이 혼합된 결과를 보였으며, 이는 다결정 구조를 갖는 MnIr의 입도 분포 특성으로 설명되어짐을 알 수 있었다.

• 한국전기전자재료학회논문지
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• 제16권7호
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• pp.604-610
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• 2003

The effects of sintering additives such as B $i_2$ $O_3$ and $V_2$ $O_{5}$ on the microwave dielectric and sintering properties of (Z $n_1$$_{-xM}$ $g_{x}$)Ti $O_3$ system were investigated. Highly dense samples were obtained for (Z $n_{0.8}$M $g_{0.2}$)Ti $O_3$ at the sintering temperature range of 870~90$0^{\circ}C$ with B $i_2$ $O_3$ and $V_2$ $O_{5}$ additions of 〈1 wt.%, respectively. The microwave dielectric properties of (Z $n_{0.8}$M $g_{0.2}$)Ti $O_3$ with 0.45 wt.%B $i_2$ $O_3$ and 0.55 wt.% $V_2$ $O_{5}$ sintered at 90$0^{\circ}C$ were as follows : Q$\times$ $f_{o}$ = 50,800 GHz, $\varepsilon$$_{r}$ = 22, and $\tau$$_{f}$ = -53 ppm/$^{\circ}C$. In order to improve temperature coefficient of resonant frequency, Ti $O_2$ was added to the above system. The optimum amount of Ti $O_2$ was 15 moi.% when sintered at 87$0^{\circ}C$, at which we could obtain following results: Q$\times$ $f_{o}$ = 32,800 GHz, $\varepsilon$$_{r}$ = 26, and$\tau$$_{f}$ = 0 ppm/$^{\circ}C$.EX>.EX>.EX>.EX>.EX>.EX>.EX>.

• 한국심리학회지 : 문화 및 사회문제
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• 제22권4호
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• pp.595-622
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• 2016

본 연구는 상담자의 눈을 통해 성인출소자의 출소 후 가족 관계 회복 과정에 대한 이해를 목적으로 한다. 이를 위해 법무부 산하의 한국법무보호복지공단 서울, 인천, 부산, 대구, 경남 지부 및 법무보호복지공단과 가족상담 연계 서비스를 진행하는 건강가정지원센터에서 출소자와 그 가정을 대상으로 숙식 및 주거 지원, 심리 지원, 자녀 학업 지원을 담당하고 있는 상담 전문가 8명에게 심층 면접을 실시하고, 면접 자료를 합의적 질적 연구 방법(CQR)으로 분석하였다. 연구결과는 다음과 같다: 상담자들은 대부분의 출소자들이 가족이 부재한 어린 시절을 보내며 부모와의 유대나 신뢰관계가 형성되지 못한 구조적·기능적 결손을 경험하였다고 인식하였다. 둘째, 상담자가 인식한 출소자의 가족, 즉 배우자와 자녀의 전형적인 특징은 자녀에게 부모의 수감사실을 숨기는 가족의 비밀이 있다는 것이다. 셋째, 상담자들은 가족에 대하여 출소자가 갖는 책임감, 가족 간의 원활한 의사소통, 가족 구성원으로서의 역할 수행을 가족 복귀의 성공요인으로 인식하는 반면 가족에 대한 의존심, 출소자에 대한 가족의 거부와 회피, 가족구성원으로서의 존재감 상실을 가족 복귀의 실패요인으로 보고 있었다. 또한 강간이나 알코올 중독, 폭력, 살인 등에 비해 횡령, 사기 등과 같은 경제사범들의 가족복귀가 비교적 원활한 것으로 인식하고 있었다. 넷째, 출소자의 가족관계 회복을 위한 상담 및 심리지원에 있어 상담자들은 휴식의 개념을 매우 중요하게 인식하고 있었고, 출소자 및 그 가족에 대한 개입을 실시하기 전에 철저한 스크리닝이 이루어져야 한다는 점을 강조하였다. 본 연구는 출소자 및 그 가정에 대한 심리적·상담적 개입 방안을 모색하고, 출소자의 가정 복귀 및 가족관계 회복을 돕는 프로그램 개발의 토대를 마련했다는 데 그 의의가 있다.

• 교통기술과정책
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• 제13권4호
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• pp.57-61
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• 2016

• Nutrition Research and Practice
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• 제8권6호
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• pp.618-624
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• 2014

BACKGROUND/OBJECTIVES: Isoflavones are widely believed to be beneficial to human health, in relation to their antioxidant potentials. Exercise can cause an imbalance between reactive oxygen species (ROS) and antioxidants. This study was conducted in order to investigate the ability of isoflavones in amelioration of oxidative stress induced by exercise. MATERIALS/METHODS: Male Sprague-Dawley rats were assigned to one of four groups: isoflavone-free with no exercise (CON-sd), isoflavone-free with exercise (CON-ex), isoflavone-supplemented with no exercise (ISF-sd), and isoflavone-supplemented with exercise (ISF-ex). Animals exercised on the treadmill for 30 minutes per day, five days per week. TBARS as a marker of oxidative stress and antioxidant enzyme activity, including SOD, GSH-px, and catalase were determined in liver tissue. Serum lipid profile was also examined. RESULTS: A significant effect of isoflavone alone was observed on abdominal fat pad mass. ISF-ex had significantly less abdominal fat pad than CON-ex. Both exercise and isoflavone treatment had significant effects on lowering plasma triglyceride (TG), thus, the ISF-ex group had a significantly lower TG level than the CON-sd group, by 30.9%. However, no differences were observed in plasma cholesterol, HDL-C, and cholesterol/HDL-C ratio. Exercise, isoflavone, and exercise-isoflavone interaction effects were significant on thiobarbituric acid reactive substances (TBARS) (P = 0.001, 0.002, and 0.005, respectively). The CON-ex group showed a higher TBARS level than the other three groups. By contrast, in the ISF-ex group, TBARS was restored to the level of the ISF-sd or CON-sd group. Isoflavone had a significant effect on superoxide dismutase (SOD) (P = 0.022) and catalase activities (P = 0.049). Significantly higher SOD and catalase activities were observed in ISF-ex than CON-ex. SOD and catalase activities showed an inverse pattern of TBARS. Taken together, isoflavones increased the activities of SOD and catalase with concomitant decreases in TBARS, indicative of decreased oxidative stress. CONCLUSIONS: Isoflavone supplementation enhances antioxidant action with attenuation of exercise-induced oxidative stress, as measured by decreases in TBARS, and inhibits body fat accumulation and plasma TG increase. Antioxidative effects ascribed to isoflavones may be partially exerted via enhancement of antioxidant enzyme activities.