• Preventive Nutrition and Food Science
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• v.15 no.3
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• pp.189-195
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• 2010

Water extracts from 20 medicinal plants, traditionally used for postmenopausal symptoms in Korea, were examined for their vasorelaxant activity in isolated rat thoracic aorta rings precontracted with norepinephrine (NE). Among the 20 medicinal plants, Cornus officinalis (CoEx, 0.3 mg/mL), Schisandra chinensis (ScEx, 0.3 mg/mL), Erythrina variegate (EvEx, 0.3 mg/mL), and Epimedium koreanum (EkEx, 0.3 mg/mL) showed rapid relaxation of endothelium-intact aorta ($69\pm4%$, $40\pm3%$, $25\pm2%$, and $23\pm3%$ of active tone induced by NE, respectively). In contrast, the extracts of Erythrina variegata (EvEx), Angelica gigas (AgEx), Pueraria thunbergiana (PtEx), and EkEx lead to gradual (i.e., long-term) relaxation to baseline in endothelium-intact vessels. The time to complete relaxation was 20～40 min. These 6 plant extracts were selected for the investigation of possible underlying mechanisms. The CoEx-, ScEx-, or EkEx-induced rapid relaxations were virtually abolished by endothelium denudation, and were significantly inhibited by pretreatment with nitric oxide (NO) synthase inhibitor $N^G$-nitro-L-arginine (L-NNA, 10 ${\mu}M$), indicating that increased formation of NO might contribute to the endothelium-mediated relaxation. In long-term responses, the endothelium denudation did not affect PtEx-induced relaxation, whereas it delayed responses by EvEx and AgEx, and significantly inhibited the effect of EkEx. Among EvEx, AgEx, and PtEx, EvEx attenuated the $CaCl_2$-induced vasoconstriction in high-potassium depolarized medium, implying that EvEx is involved in inhibition of the extracellular calcium influx to smooth muscle through voltage dependent calcium channels. These results provide the scientific rationale for the interrelationships between the use of 20 medicinal plants and their effects on cardiovascular health in estrogen deficient conditions.

• Journal of the Korean Society of Food Culture
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• v.22 no.4
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• pp.454-461
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• 2007

Antioxidative and antimicrobial activities were carried out on the Citrus Unshju peel solvent extracts in order to discover new functional activities. The amounts of polyphenol in 70% metanol extract (MtEx) was measured as 836.8 mg% in Citrus Unshju peel. The EDA (electron donating ability) of 0.01, 0.02 and 0.1% MtEx in Citrus Unshju peel were measured as levels of 81.3, 86.0 and 89.6%. The nitrite scavenging effects of Citrus peel were also determined as the levels of 34.4% (pH 1.2) and 19.5% (pH 7.0). The pH of react solution was more acidic, the nitrite scavenging effect was more increased. The order of antioxidatives was shown as TBHQ > BHT > TOC > ChEx > EaEx > EtEx > WaEx > Control in corn germ oil and TBHQ > ChEx > EaEx > BHT > EtEx > WaEx > TOC > Control in canola oil. A number of the extracts were certified to have antimicrobial activities for a small number of micro-organisms, similar gram negative and positive micro-organisms. According to the results above, it was summerized that Citrus Unshju peel had the higher total polyphenol, EDA, nitrite scavenging effects and antimicrobial activities. Also isolated extract from ChEx and EaEx had high antioxidative, these effects were very similar to that of ${alpha}$-tocopherol and BHT. It would be proposed that Citrus peel can become a new natural source for antioxidative agents in future food industry.

• Journal of Nutrition and Health
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• v.39 no.1
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• pp.3-10
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• 2006

Effects of garlic powder supplementation on blood lipid profile and antioxidant system were investigated in rats with and without swimming exercise. Sprague-Dawley rats of four experimental groups were fed for 4 weeks diets containing $15\%$ beef tallow and $1\%$ cholesterol; control without garlic and exercise, Go with $2\%$ garlic alone, Ex with exercise alone, GoEx with $2\%$ garlic and exercise. Rats were trained 40 min a days a days a week. Group Ex and GoEx showed significant lowering in body weight gain and fat accumulation. In Go, Ex and GoEx, plasm TG and LDL-C were lower and HDL-C was higher, although not significantly, compared to levels in control. Total cholesterol was significantly reduced in group Go, and Ex and GoEx were lower than control. The total/HDL cholesterol ratio was also found to be significantly different, decreasing the ratios in Go, Ex and GoEx. The hepatic TBARS increased significantly in group Ex $(51.7{\pm}3.43nM/g\;liver)$, while TBARS in Go and GoEx were low $(35.68{\pm}3.61,\;39.30{\pm}5.55nM/g\;liver)$ and similar to control's one. The activity of hepatic SOD in Go and GoEx tended higher than control and Ex without garlic. The hepatic catalase showed significantly the highest activity in Go. Activity of GSH-px was significantly low in Ex with $0.14{\pm}0.03$ unit/mg protein, and control, Go and GoEx had higher activities of $0.23{\pm}0.08,\;0.20{\pm}0.07,\;0.22{\pm}0.01\;unit/mg$ protein, respectively. Lower activities of antioxidant enzymes in Ex are likely to associated with the highest level of TBARS. It seems that a decrease in TBARS in GoEx relative to Ex was related to the increase in GSHpx and SOD with garlic supplemented, which led to compensate the oxidative stress from exercise. The results suggests that exercise or garlic supplement exerts blood lipid attenuating effect. In adition, garlic supplementation could strengthen the antioxidant potential against exercise-induced oxidants, partly by modulating oxidant enzyme activity. These effects of garlic may make it a beneficial agent on CVD.

• Korean Journal of Food Science and Technology
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• v.36 no.2
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• pp.262-267
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• 2004

Processed foods were developed using amaranth starch and flours. Amaranth seeds were untreated (UT), defatted (DF), germinated (GM), roasted (RT), popped (POP), and extruded (EX1 and EX2). Amaranth flours showed A-type pattern on X-ray diffractograms, while crystallinity was not observed in POP, EX1, and EX2. POP and EX1 showed highest (740.3%) and lowest (38.5%) water-binding capacities, respectively. Transmittances of RT, POP, EX1, and EX2 flour suspensions were higher than those of others. Transmittance of amaranth starch and flours differed with processing methods. RT, POP, EX1, and EX2 showed higher transmittance at $60^{\circ}C$. Initial pasting temperature of amaranth flours by RVA were $68.1-73.0^{\circ}C$, and peak viscosities of GM and RT were 31.6 and 401.1 RVU, respectively. Melting endotherms of POP, EX1, and EX2 were not observed in DSC thermograms.

• The Korean Journal of Mycology
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• v.13 no.1
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• pp.27-40
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• 1985

Two-hundred fifty specimens of Discomycetes were collected, for the most part, at Gwangneung, Mt. Deokyu, Mt. Seulak, Mt. Sungsu, Mt. Paldal, from March, 1982 to July, 1984. These Discomycetes were identified and classified into 2 orders, 9 families, 18 genera and 23 species. Among them, Helvella pezizoides Afz. ex Fr., Peziza celtica (Boud.) Moser, Humaria hemisphaerica (Wiggers ex Fr.) Fuckel, Trichophaea gregaria (Rehm) Boud., Trichoglossum walteri(Berk.) Durand, Spathularia flavida Pers. ex Fr., Arachnopeziza aurelia (Pers. ex Fr.) Fuckel, Rutstroemia americana (Durand) White, Rutstroemia macrospora (Peck) Kanouse apud Wehmeyer forma gigaspora Korf, Ascocoryne cylichnium (Tul.) Korf, Bisporella citrina (Batsch. ex Fr.) Korf et Carpenter, Chlorosplenium chlora (Schw. ex Fr.) Curtis, Chlorociboria aeruginascens (Nyl.) Kanouse ex Ramamurthi, Korf et Batra subsp. aeruginascens, Hymenoscyphus scutula (Pers. ex Fr.) Phillips, Cyathicula cyathoidea (Bull. ex Fr.) de Thumen were new records in Korea. These species are described and their Korean names are designated.

• Journal of the Korean Applied Science and Technology
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• v.40 no.5
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• pp.925-935
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• 2023

It was investigated whether PPARα activator more effectively inhibits angiogenesis of white adipose tissue in exercise mice that ate high fat diet compared to non-exercise mice that ate high fat diet. Male mice were randomly divided into a control group not treated with a PPARα activator fenofibrate and exercise (Con), a group treated with fenofibrate alone (FF), a group treated with exercise alone (Ex), and a group treated with a combination of fenofibrate and exercise (Ex+FF). (Ex+FF). All mice was fed high-fat diet for 8 weeks. The weight of white adipose tissue and the size of white adipocytes decreased in FF, Ex, and Ex+FF compared to Con, and decreased more in Ex+FF Ex+FF compared to FF. In white adipose tissue, the gene expression of MMPs and angiogenic factors decreased in FF, Ex, and Ex+FF compared to Con, and more decreased in Ex+FF compared to FF. On the other hand, gene expression of angiogenic inhibitors increased in FF, Ex and Ex+FF compared to Con, and increased more in Ex+FF compared to FF. Therefore, this study revealed that the combined treatment of fenofibrate and exercise effectively inhibits the angiogenesis of white adipose tissue, reducing the increase in white adipose tissue and suppressing abdominal obesity, rather than the single treatment of fenofibrate.

• Journal of Information Technology Applications and Management
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• v.19 no.2
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• pp.59-78
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• 2012

The purpose of this longitudinal case study is to shed light on the reliability problems of IS performance evaluation by analyzing the discrepancy between ex ante evaluation in 2011 and ex post evaluation in 2012. Through an information system development project of a public enterprise, the gap between ex ante and ex post evaluation was ascertained and the causes as to why such gap occurs and the success factors that can solve the problems were derived. The ex ante evaluation of IS performance was performed based on both IS success model and BSC model and the ex post evaluation was carried out at the time after the target system has been built up by applying the evaluation measures and process that are similar to the ex ante evaluation. In the ex ante evaluation the business performance improved by the target system was estimated to 18.2%. On the other hand, it was seen as being low at 15.2% in the ex post evaluation and the differences were found to be statistically significant in 6 out of 10 measures. The reasons as to why such gap occurs were diagnosed as being of 2 types : (1) changes in the evaluation psychology according to the differences in the evaluation objectives; and (2) excessive expectation levels of the target system that is formed at the time of the ex ante evaluation. In other words, the users who have excessive expectations tend to overestimate in the ex ante evaluation and, in the ex post evaluation, tend to underestimate lower than the actual performance mainly due to disappointment on the results that do not meet the early expectations. As solutions to overcome the reliability problem of ex ante evaluation, 3 factors were derived : (1) the temperance of excessive expectation levels of the users; (2) a clear definition of the scope and functionality of the target system; and (3) actual commitments for the evaluations of IT performance.

• Journal of Korean Medicine for Obesity Research
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• v.17 no.2
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• pp.77-86
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• 2017

Objectives: This study examined the effects of salvianolic acid B (SAB) on exhaustive exercise-induced cardiac muscle damage to rats. Methods: The study was carried out with 12-week-old young adult male Sprague-Dawley rats. Thirty-six rats were divided into 3 groups; normal (n=12), exhaustive exercise group (ExS, n=12) and exhaustive exercise with SAB (ExS+SAB, n=12). Five days before exhaustive exercise, SAB were medicated for 5 days in ExS+SAB group. Rats in ExS and ExS+SAB group were forced to swim for 150 minutes and then they were sacrificed, while rats in normal group were sacrificed at rest. After that, blood was collected and cardiac muscle tissue damage indices were analyzed. Results: Serum aspartate transaminase activity and lactate dehydrogenase activity were significantly lower in ExS+SAB group than in ExS group. Serum creatine phosphokinase activity of ExS+SAB was significantly lower than ExS group. However, the content of serum creatinine had no difference between ExS and ExS+SAB group. In the H&E stained left ventricle myocardium, ExS group showed signs of myocardial damage such as sporadic fragmentation of myocardial fibers, interstitial edema, cytoplasmic eosinophilia and neutrophils infiltration. However, ExS+SAB group alleviated the severity of the signs of myocardial damage. In the myocardial dihydroethidium staining, optical density was remarkably decreased in ExS+SAB group compared to ExS group. Furthermore, the up-regulation of Bax/Bcl-2 ratio was observed in ExS+SAB group compared with ExS group. Conclusions: The above results suggest that SAB may protect cardiac muscle damage via antioxidant activity and prevention of apoptosis.

• Journal of the Korean Society of Marine Environment & Safety
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• v.27 no.6
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• pp.875-882
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• 2021

To minimize occupational noise induced hearing loss, it is recommended that workers should not be exposed to noise levels exceeding 85 dBA for over 8 h. In the present study, noise exposure levels were measured for seven workers based on their tasks on a training ship. The A-weighted noise exposure level (L_ex,24h) was measured by taking into account the A-weighted equivalent continuous sound level (L_Aeq,i), duration (h) and noise contribution (L_ex,24h,i) from the workers' locations. Results are thus obtained for different job categories as follows: officer group L_ex,24h=56.1 dB, navigation crew L_ex,24h=58.9 dB, navigation cadet L_ex,24h=62.0 dB, ship's cook L_ex,24h=64.3 dB, engine cadet L_ex,24h=91.1 dB, engineer L_ex,24h=91.1 dB, and engine crew L_ex,24h=95.1 dB. It was determined that the engineers, engine crews, and engine cadets in charge of machinery must wear hearing protection devices. By wearing hearing protection devices when working in highly noisy engine rooms, it is estimated that the noise expose levels could be reduced by the following amounts: engineer L_ex,24h=23.1 dB, engine Crew L_ex,24h=24.4 dB, and engine cadet L_ex,24h=21.5 dB. Moreover, if the no. 2 lecture room and mess room bottom plates in the cadets accommodations were improved to the 64 mm A-60-class floating plates, then further reductions are possible as follows: navigation cadet L_ex,24h=4.3 dB and engine cadet L_ex,24h=1.8 dB.

• The Journal of Economics, Marketing and Management
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• v.3 no.4
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• pp.21-27
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• 2015

With the recent increasing interest in sustainability management, the latest environmental report tends to be substituted by the expanded sustainability management report. In this work, I would like to introduce the management pattern of a global enterprise that values environmental soundness (environmental friendly) and implements eco-friendly measures. The enterprise chosen in this study is FedEx. In this article, FedEx case is presented how companies can adopt environmental friendly management in their businesses. FedEx has maintained an eco-friendly management since the introduction of the company's eco-friendly transport trucks in 2003, following its development in 2000. In 2005, it installed a solar power plant that can supply up to 80% of the electricity consumed by Oakland Logistics Center in California, USA. FedEx has published the "Global Enterprise Citizenship Report," which contains its business developments in 2009. FedEx has worked hard to minimize the influence caused by packaging of goods to the environment and appealed to customers to use recycled products as much as they can. FedEx also encourages customers to use packaging materials efficiently. A considerable amount of energy has been expended in the eco-friendly programs of FedEx. Although thousands of FedEx vehicles and aircraft operate daily with using large amounts of electricity and fuel, FedEx focuses on energy savings and global environment protection.